Ventricular tachycardia: who works on it

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Terminated, withdrawn and suspended trials with the reason the sponsor gave in the registry, quoted word for word.

• Terminated

  Effectiveness of CRD-4730 in Participants With Catecholaminergic Polymorphic Ventricular Tachycardia (CPVT)

  NCT06005428· Cardurion Pharmaceuticals, Inc.· Updated 27 May 2026

  “The early termination of the clinical trial is due to an internal administrative and business decision, the study is not being terminated for safety reasons.”Registry text, quoted unchanged. Source

• Terminated

  Defining the Risk of Ventricular Tachycardia in Genetic Forms of Early-onset Atrial Fibrillation

  NCT06647459· Vanderbilt University Medical Center· Updated 6 May 2026

  “Grant proposal was sent to NIH 3 times but did not score well enough to receive funding”Registry text, quoted unchanged. Source

• Terminated

  Effect of Sodium Zirconium Cyclosilicate on Arrythmia-related Cardiovascular Outcomes in Participants on Chronic Hemodialysis With Recurrent Hyperkalemia (DIALIZE-Outcomes)

  NCT04847232· AstraZeneca· Updated 18 Jun 2025

  “The event rate observed in the study continued to be below primary assumptions, so that the completion of the study within a reasonable timeframe was deemed very unlikely.”Registry text, quoted unchanged. Source

• Terminated

  Study of Cardiac PET/CT Imaging to Guide Ablation Treatment of Ventricular Tachycardia

  NCT02962076· Khaled Awad, MD· Updated 24 Dec 2024

  “Investigator departing institution and enrollment not met.”Registry text, quoted unchanged. Source

• Terminated

  Treatment of an Inherited Ventricular Arrhythmia

  NCT05122975· RyCarma Therapeutics, Inc.· Updated 19 Sept 2024

  “Due to challenges in recruiting patients.”Registry text, quoted unchanged. Source

• Terminated

  Catheter Ablation of Ventricular Arrhythmia Reduces Skin Sympathetic Activity

  NCT04837183· Mayo Clinic· Updated 3 Jul 2024

  “This study was closed before its planned primary completion date because early data indicated that VT ablation had little impact on sympathetic nerve activity in short-term follow up.”Registry text, quoted unchanged. Source

• Withdrawn

  TcMS to Treat Ventricular Tachycardia

  NCT05016921· University of Pennsylvania· Updated 4 Apr 2024

  “Alternate study pursued”Registry text, quoted unchanged. Source

• Withdrawn

  Phase I/II Randomized Study of Stereotactic Ablative Radiotherapy (SABR) Versus Standard of Care for Refractory Structural Cardiac Arrhythmias (SABR-HEART)

  NCT05084391· M.D. Anderson Cancer Center· Updated 13 Feb 2024

  “0 participant accrual”Registry text, quoted unchanged. Source

• Withdrawn

  Noninvasive Cardiac Radioablation for Ventricular Tachycardia Refractory to Medication and Catheter Ablation

  NCT04757688· John Stahl· Updated 9 Nov 2022

  “Difficulty with accrual”Registry text, quoted unchanged. Source

• Suspended

  Effect of Multielectrode Versus Point-by-Point Mapping on Recurrence of Ventricular Tachycardia in Ischemic Heart Disease

  NCT05203484· Helios Health Institute GmbH· Updated 19 Aug 2022

  “Principal investigator left Heart Center Leipzig.”Registry text, quoted unchanged. Source

Trials whose registry record says individual participant data (IPD) will be shared.

• A Study Assessing Arrhythmia Mapping With a Multi-Electrode Mapping Catheter

  NCT07116525· Biosense Webster, Inc.· Source

• Dynamic Voltage Mapping to Personalise the Ventricular Tachycardia Substrate

  NCT07573579· Liverpool Heart and Chest Hospital NHS Foundation Trust· Source

• Using Non-Invasive Mapping To Eliminate Structural Heart Disease Ventricular Tachycardia

  NCT07759427· University of Warwick· Source

• Study Evaluating Dexmedetomidine in the Acute Treatment of Electrical Storm

  NCT06281977· Ottawa Heart Institute Research Corporation· Source

• To Evaluate the Delivery Timing Safety and Efficacy of AntiTachycardia Pacing (BIO|ATP)

  NCT05426785· Biotronik SE & Co. KG· Source

• Optimised Decrement Evoked Potential (DeEP) Mapping to Guide Ventricular Tachycardia (VT) Ablation in Patients With Structural Heart Disease VT

  NCT06937983· University Hospitals Coventry and Warwickshire NHS Trust· Source

• AI-guided Prediction and Treatment of Cardiac Arrest

  NCT07452016· MetroHealth Medical Center· Source

• Improving Patient Reported Outcome Measures in Catheter Ablation

  NCT04499326· Barts & The London NHS Trust· Source

• Predicting Severe Cardiac Arrhythmias in the Perioperative Period Using AI-ECG

  NCT07348991· I.M. Sechenov First Moscow State Medical University· Source

• Sympathetic Denervation by Video-assisted Thoracoscopy in Control of Cardiac Arrhythmias in Patients With Chagas Disease

  NCT04239144· University of Sao Paulo General Hospital· Source

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