Columbus

The trials here

What the 12 trials at this site are about, from their registry records.

Conditions

• Amyloidosis4 trials
• High blood pressure4 trials
• Chronic kidney disease1 trial
• Crohn's disease1 trial
• Metastatic breast cancer1 trial
• Neuromyelitis optica (NMOSD)1 trial
• Prostate cancer1 trial

Phase

• Phase 35 trials
• Phase 24 trials
• Phase 11 trial

Status

• Completed5 trials
• Recruiting5 trials
• Enrolling by invitation1 trial
• Not yet recruiting1 trial

Lead sponsor

• Alnylam Pharmaceuticals8 trials
• Alexion Pharmaceuticals, Inc.1 trial
• Arvinas Androgen Receptor, Inc.1 trial
• Olema Pharmaceuticals, Inc.1 trial
• Shattuck Labs, Inc.1 trial

Running trials

• Recruiting

  A Study of SL-325 in Crohn's Disease Patients

  NCT07753850· Phase 2· Shattuck Labs, Inc.· Source

  Contact: Shattuck Medical Director

• Recruiting

  Palazestrant in Combination With Ribociclib for the First-line Treatment of ER+/HER2- Advanced Breast Cancer

  NCT07085767· Phase 3· Olema Pharmaceuticals, Inc.· Source

  Contact: Olema Pharmaceuticals, Inc.

• Recruiting

  Zilebesiran in Patients With Hypertension Not Adequately Controlled and With Either Established Cardiovascular Disease or High Risk for Cardiovascular Disease

  NCT07181109· Phase 3· Alnylam Pharmaceuticals· Source

• Recruiting

  TRITON-CM: A Study to Evaluate Nucresiran in Patients With Transthyretin Amyloidosis With Cardiomyopathy

  NCT07052903· Phase 3· Alnylam Pharmaceuticals· Source

• Enrolling by invitation

  A Study to Evaluate Vutrisiran in Patients With Transthyretin Amyloidosis With Cardiomyopathy

  NCT06679946· Phase 3· Alnylam Pharmaceuticals· Source

• Recruiting

  Registry of Patients With AQP4+ NMOSD Treated With Alexion C5 Inhibitor Therapies

  NCT05966467· Alexion Pharmaceuticals, Inc.· Source

  Contact: Jacqueline Nicholas

• Recruiting

  ConTTRibute: A Global Observational Study of Patients With Transthyretin (TTR)-Mediated Amyloidosis (ATTR Amyloidosis)

  NCT04561518· Alnylam Pharmaceuticals· Source

Recruiting at the same time

How many trials recruit for the same indication here at once. A count, not a rating.

• Amyloidosis3 recruiting
• Crohn's disease1 recruiting
• High blood pressure1 recruiting
• Metastatic breast cancer1 recruiting
• Neuromyelitis optica (NMOSD)1 recruiting

Closed trials

• Completed

  Zilebesiran as Add-on Therapy in Patients With High Cardiovascular Risk and Hypertension Not Adequately Controlled by Standard of Care Antihypertensive Medications (KARDIA-3)

  NCT06272487· Phase 2· Alnylam Pharmaceuticals· Source

• Completed

  Trial of ARV-110 and Abiraterone in Participants With Metastatic Prostate Cancer

  NCT05177042· Phase 1· Arvinas Androgen Receptor, Inc.· Source

• Completed

  Zilebesiran as Add-on Therapy in Patients With Hypertension Not Adequately Controlled by a Standard of Care Antihypertensive Medication (KARDIA-2)

  NCT05103332· Phase 2· Alnylam Pharmaceuticals· Source

• Completed

  A Study to Evaluate Efficacy and Safety of ALN-AGT01 in Patients With Mild To-Moderate Hypertension

  NCT04936035· Phase 2· Alnylam Pharmaceuticals· Source

• Completed

  HELIOS-A: A Study of Vutrisiran (ALN-TTRSC02) in Patients With Hereditary Transthyretin Amyloidosis (hATTR Amyloidosis)

  NCT03759379· Phase 3· Alnylam Pharmaceuticals· Source