Instituto do Coração - HCFMUSP

Running trials

• Not yet recruiting

  A Research Study to Investigate How Well the Medicine CagriSema Lowers High Blood Pressure in People Living With High Blood Pressure and Obesity

  NCT07919405· Phase 3· Novo Nordisk A/S· Source

• Not yet recruiting

  A Research Study to Look at How Well Zenagamtide Works Compared to Placebo in People With Established Atherosclerotic Cardiovascular Disease and Either Overweight or Obesity

  NCT07861100· Phase 3· Novo Nordisk A/S· Source

• Recruiting

  AMBITION 7: A Research Study Investigating How Well Zenagamtide Lowers Blood Sugar and Body Weight Compared to Insulin Glargine in People With Type 2 Diabetes and Increased Risk of Diseases That Affect the Heart and Blood Vessels Treated With 1-3 Other Diabetes Medications

  NCT07797335· Phase 3· Novo Nordisk A/S· Source

• Recruiting

  A Research Study to Look at How Well NNC0487-0111 Works Compared to Placebo in People With Heart Failure and Obesity

  NCT07567001· Phase 3· Novo Nordisk A/S· Source

• Active, not recruiting

  Evaluating the Impact of Maridebart Cafraglutide on Cardiovascular Outcomes in Participants With Atherosclerotic Cardiovascular Disease and Overweight or Obesity

  NCT07037433· Phase 3· Amgen· Source

• Recruiting

  Maridebart Cafraglutide in Heart Failure With Preserved or Mildly Reduced Ejection Fraction and Obesity

  NCT07037459· Phase 3· Amgen· Source

• Recruiting

  Effect of Point-of-care Analysis of Ultrasensitive Troponin I on Length of Hospital Stay in Patients With Cardiac Chest Pain (POC Troponina)

  NCT06861582· University of Sao Paulo· Source

• Recruiting

  FAPO-2: Cardiac Patient Monitoring Tool for Clinical Observation and Arrhythmia Detection

  NCT07174206· University of Sao Paulo· Source

• Recruiting

  ATTR Amyloid Cardiomyopathy: Characterization of Extracellular Vesicles as Potential Disease Stratifiers and Prognostic Biomarkers

  NCT07314268· University of Sao Paulo General Hospital· Source

• Active, not recruiting

  ADVENT Post Approval Study

  NCT06431815· Boston Scientific Corporation· Source

• Recruiting

  Open-label Extension Study of Seralutinib in Adult Subjects With PAH (PROSERA-EXT)

  NCT06274801· Phase 3· Gossamer Bio USA, Inc.· Source

• Recruiting

  Isolated Resistance Training and Neuromuscular Electrical Stimulation in Patients With Femoral Intra Aortic Balloon Pump.

  NCT06316349· University of Sao Paulo General Hospital· Source

• Recruiting

  Effect of Resistance Training in Patients on the Waiting List for Heart Transplant

  NCT06426173· University of Sao Paulo General Hospital· Source

• Recruiting

  Inotropic Effects of Vasopressin Versus Noradrenaline In Patients With Vasoplegic Syndrome After Cardiac Surgery

  NCT06934798· Phase 4· University of Sao Paulo· Source

• Recruiting

  Frailty, Physical Capacity and Lung Function in Postoperative Pulmonary Endarterectomy Patients

  NCT06286891· University of Sao Paulo General Hospital· Source

• Active, not recruiting

  Association Between GalectiN-3 and pOSt-operative atrIal Fibrillation After Coronary Artery bypaSs Graft

  NCT06768528· University of Sao Paulo General Hospital· Source

• Enrolling by invitation

  An Extension Study to Assess Long-Term Safety of Eplontersen in Adults With Transthyretin-Mediated Amyloid Cardiomyopathy (ATTR-CM)

  NCT05667493· Phase 3· Ionis Pharmaceuticals, Inc.· Source

• Active, not recruiting

  Open-Label Safety Study of Acoramidis (AG10) in Symptomatic ATTR Participants

  NCT04988386· Phase 3· Eidos Therapeutics, a BridgeBio company· Source

• Active, not recruiting

  A Clinical Study of Sotatercept (MK-7962) in People With Pulmonary Arterial Hypertension (MK-7962-038)

  NCT07218029· Phase 3· Merck Sharp & Dohme LLC· Source

• Enrolling by invitation

  A Study Evaluating the Long-Term Efficacy and Safety of Ralinepag in Subjects With PAH Via an Open-Label Extension

  NCT03683186· Phase 3· United Therapeutics· Source

Recruiting at the same time

How many trials recruit for the same indication here at once. A count, not a rating.

• Heart failure4 recruiting
• High blood pressure4 recruiting
• Obesity4 recruiting
• Pulmonary arterial hypertension3 recruiting
• Amyloidosis2 recruiting
• Coronary artery disease2 recruiting
• Atrial fibrillation1 recruiting
• Type 1 diabetes1 recruiting
• Type 2 diabetes1 recruiting

Closed trials

• Completed

  Frailty, Physical Capacity and Lung Function in Postoperative Cardiac Surgery Patients

  NCT06247358· University of Sao Paulo General Hospital· Source

• Completed

  Assessment of Smartwatch SAMSUNG to Monitor Sleep Quality: an Observational Prospective Study - SleepEx2 Protocol

  NCT06363656· University of Sao Paulo General Hospital· Source

• Completed

  Efficacy and Safety of Seralutinib in Adult Subjects With PAH (PROSERA)

  NCT05934526· Phase 3· GB002, Inc.· Source

• Completed

  SELECT-LIFE: A Research Study Looking at Long-term Effects of Semaglutide in People Who Took Part in the SELECT Cardiovascular Outcomes Trial

  NCT04972721· Novo Nordisk A/S· Source

• Completed

  A Study to Evaluate Astegolimab in Participants With Chronic Obstructive Pulmonary Disease

  NCT05595642· Phase 3· Hoffmann-La Roche· Source

• Completed

  ZEUS - A Research Study to Look at How Ziltivekimab Works Compared to Placebo in People With Cardiovascular Disease, Chronic Kidney Disease and Inflammation

  NCT05021835· Phase 3· Novo Nordisk A/S· Source

• Completed

  POST-CABGDM: Empagliflozin in Perioperative CABG

  NCT04523064· Phase 4· University of Sao Paulo General Hospital· Source

• Completed

  CARDIO-TTRansform: A Study to Evaluate the Efficacy and Safety of Eplontersen (Formerly Known as ION-682884, IONIS-TTR-LRx and AKCEA-TTR-LRx) in Participants With Transthyretin-Mediated Amyloid Cardiomyopathy (ATTR CM)

  NCT04136171· Phase 3· Ionis Pharmaceuticals, Inc.· Source

• Completed

  Optimal Blood Pressure for the prevenTIon of Major vAscuLar Events in Patients With DIABETES Mellitus (OPTIMAL-DIABETES)

  NCT04040634· Hospital Israelita Albert Einstein· Source

• Completed

  Effect of Evolocumab in Patients at High Cardiovascular Risk Without Prior Myocardial Infarction or Stroke

  NCT03872401· Phase 3· Amgen· Source

• Completed

  A Study Evaluating the Efficacy and Safety of Ralinepag to Improve Treatment Outcomes in PAH Patients

  NCT03626688· Phase 3· United Therapeutics· Source

• Completed

  Impact of Interval Training on Sympathetic Hyperactivity and Vascular Function

  NCT04248894· University of Sao Paulo General Hospital· Source

Conditions

Diseases this institution publishes on or runs trials for.

• Coronary artery disease41 works · 4 trials
• Pulmonary arterial hypertension23 works · 6 trials
• Obstructive sleep apnoea20 works · 0 trials
• Amyloidosis18 works · 4 trials
• Hypertrophic cardiomyopathy17 works · 0 trials
• Ventricular tachycardia12 works · 0 trials
• Familial hypercholesterolaemia11 works · 0 trials
• Dilated cardiomyopathy10 works · 0 trials
• Myocarditis9 works · 0 trials
• High blood pressure6 works · 8 trials
• Fabry disease4 works · 0 trials