Acute lymphoblastic leukaemia trials in United States

In United States 232 Also abroad 564

232 trials · From ClinicalTrials.gov, checked 11 November 2026. Ask the study team whether a trial fits you.

No phaseTaking people
Cancer Experience Registry (CER) for Cancer Patients and Caregivers
Where
Washington D.C.
Age
18 years and over
People
15,000
Run by
Cancer Support Community, Research and Training Institute, Philadelphia
See details and how to joinNCT02333604
Phase 1Taking people
Testing the Addition of an Anti-cancer Drug, Lenalidomide, to the Usual Combination Chemotherapy Treatment ("EPOCH") for Adult T-Cell Leukemia-Lymphoma (ATLL)
Where
Atlanta, Basking Ridge, City of Saint Peters, Columbus, Commack, Creve Coeur, Harrison, Middletown, Mineola, Montvale, New York, Richmond, St Louis, Uniondale
Age
18 years and over
People
30
Run by
National Cancer Institute (NCI)
See details and how to joinNCT04301076
No phaseTaking people
Pharmacokinetic Study of Venetoclax Tablets Crushed and Dissolved Into a Solution
Where
Atlanta, Aurora, Cincinnati, Houston, Milwaukee, Philadelphia
Age
0 years to 38 years
People
30
Run by
Children's Hospital Medical Center, Cincinnati
See details and how to joinNCT06131801
Phase 1Taking people
Prophylactic DLI-X for Leukemia Relapse After HCT
Where
Tucson
Age
Up to 65 years
People
180
Run by
University of Arizona
See details and how to joinNCT07254793
No phaseNot yet taking people in United States
my.naviGATE: A Guide to After-Treatment Effects for Adolescents and Young Adults
Where
Boston
Age
15 years to 24 years
People
143
Run by
Dana-Farber Cancer Institute
See details and how to joinNCT07516353
Phase 1Taking people
A Study of LP-118 In Combination With Ponatinib, Dexamethasone And Blinatumomab For Adults With Newly-Diagnosed, BCR::ABL1-Positive Acute Lymphoblastic Leukemia (ALL)
Where
Charlotte, Winston-Salem
Age
18 years and over
People
26
Run by
Wake Forest University Health Sciences
See details and how to joinNCT07614022
No phaseTaking people
Tissue, Blood, and Body Fluid Sample Collection From Patients With Hematologic Cancer
Where
Chapel Hill
Age
18 years to 120 years
People
15,000
Run by
UNC Lineberger Comprehensive Cancer Center
See details and how to joinNCT01137643
Phase 2Taking people
Inotuzumab Ozogamicin and Blinatumomab With or Without Ponatinib in Treating Patients With Newly Diagnosed, Recurrent, or Refractory CD22-Positive B-Lineage Acute Lymphoblastic Leukemia
Where
Aberdeen, Allentown, Alton, Anchorage, Ankeny, Ann Arbor, Arroyo Grande, Atlanta, Ballwin, Baltimore, Bellevue, Bellingham, Bend, Bethlehem, Birmingham, Bloomington, Boise, Bolivar, Branson, Brighton, Buffalo, Burbank, Burr Ridge, Canton, Cape Girardeau, Carbondale, Caro, Carson City, Carterville, Carthage, Centralia, Chadds Ford, Chapel Hill, Chelsea, Chicago, Cincinnati, City of Saint Peters, Clackamas, Clarkston, Clive, Clovis, Columbus, Coos Bay, Creve Coeur, Decatur, Des Moines, Detroit, Dixon, Duarte, Durham, East China Township, East Stroudsburg, Eau Claire, Edmonds, Effingham, Eureka, Evanston, Everett, Farmington, Flint, Fort Lauderdale, Fort Smith, Fruitland, Galesburg, Garden City, Glenview, Great Bend, Greenville, Grosse Pointe Woods, Hazleton, Henderson, Highland Park, Homer Glen, Irvine, Issaquah, Jefferson City, Joplin, Jupiter, Kansas City, Kennewick, Kewanee, Kingman, Lacey, La Jolla, Lake Forest, Lake Success, Lansing, Las Vegas, Lewes, Livonia, Longview, Macomb, Madison, Manhasset, Marlette, Marshfield, Maywood, Melrose Park, Menomonee Falls, Meridian, Millville, Milwaukee, Minocqua, Missoula, Morgantown, Mount Vernon, Nampa, Newark, Newberg, New Berlin, New Hyde Park, New Lenox, New Orleans, New York, Oak Creek, O'Fallon, Oklahoma City, Omaha, Orange, Oregon City, Orland Park, Ottawa, Pahrump, Palo Alto, Pekin, Peoria, Peru, Philadelphia, Pontiac, Portland, Princeton, Redmond, Rehoboth Beach, Reno, Renton, Rice Lake, Richmond, Rochester, Rochester Hills, Rolla, Saginaw, Sainte Genevieve, Saint Joseph, Seaford, Seattle, Sedro-Woolley, Shelton, Springfield, Sterling Heights, Stevens Point, St Louis, Stony Brook, Sullivan, Tawas City, Twin Falls, Vancouver, Walla Walla, Warren, Washington, Washington D.C., Waukee, West Bend, West Branch, West Chester, Weston, Westwood, Wilmington, Winston-Salem, Yakima, Yelm, Ypsilanti
Age
18 years and over
People
84 worldwide
Run by
National Cancer Institute (NCI)
See details and how to joinNCT03739814
No phaseTaking people
A Multi-site Study to Evaluate the Persistence of Protective Immunity to Routine Childhood Vaccinations in Participants With B-ALL/Ly Who Have Received Blinatumomab
Where
Little Rock, Springdale
Age
1 year to 23 years
People
300
Run by
Arkansas Children's Hospital Research Institute
See details and how to joinNCT07422337
Phase 1Taking people
Alpha/Beta CD19+ Depleted Haploidentical Transplantation + Zometa for Pediatric Hematologic Malignancies and Solid Tumors
Where
Madison
Age
7 months to 21 years
People
22
Run by
University of Wisconsin, Madison
See details and how to joinNCT02508038
Phase 2Taking people
A Study Testing the Combination of Dasatinib or Imatinib to Chemotherapy Treatment With Blinatumomab for Children, Adolescents, and Young Adults With Philadelphia Chromosome Positive (Ph+) or ABL-Class Philadelphia Chromosome-Like (Ph-Like) B-cell Acute Lymphoblastic Leukemia (B-ALL)
Where
Akron, Albany, Albuquerque, Allentown, Ann Arbor, Asheville, Atlanta, Augusta, Aurora, Austin, Baltimore, Bethesda, Birmingham, Boise, Boston, Buffalo, Burlington, Chapel Hill, Charlotte, Charlottesville, Chicago, Cincinnati, Cleveland, Columbia, Columbus, Corpus Christi, Dallas, Dayton, Des Moines, Detroit, Downey, Durham, El Paso, Falls Church, Fargo, Fort Myers, Fort Worth, Gainesville, Grand Rapids, Green Bay, Greenville, Hackensack, Hartford, Hershey, Hollywood, Honolulu, Houston, Indianapolis, Iowa City, Jackson, Jacksonville, Kalamazoo, Kansas City, Knoxville, Las Vegas, Lebanon, Lexington, Little Rock, Loma Linda, Long Beach, Los Angeles, Louisville, Lubbock, Macon, Madera, Madison, Miami, Milwaukee, Mineola, Minneapolis, Morristown, Nashville, Neptune City, New Brunswick, New Haven, New Hyde Park, New Orleans, New York, Norfolk, Oakland, Oak Lawn, Oklahoma City, Omaha, Orange, Orlando, Palo Alto, Park Ridge, Paterson, Pensacola, Peoria, Philadelphia, Phoenix, Pittsburgh, Providence, Richmond, Roanoke, Rochester, Sacramento, Salt Lake City, San Antonio, San Diego, San Francisco, Savannah, Scarborough, Seattle, Sioux Falls, Spokane, Springfield, St Louis, Stony Brook, St. Petersburg, Syracuse, Tacoma, Tampa, Temple, The Bronx, Toledo, Tucson, Valhalla, Washington D.C., West Palm Beach, Wilmington, Winston-Salem, Worcester
Age
366 days to 46 years
People
222 worldwide
Run by
National Cancer Institute (NCI)
See details and how to joinNCT06124157
Phase 2Taking people
Testing the Addition of the Anti-cancer Drug Venetoclax and/or the Anti-cancer Immunotherapy Blinatumomab to the Usual Chemotherapy Treatment for Infants With Newly Diagnosed KMT2A-rearranged or KMT2A-non-rearranged Leukemia
Where
Akron, Albany, Allentown, Anchorage, Ann Arbor, Atlanta, Aurora, Austin, Baltimore, Birmingham, Boise, Boston, Buffalo, Chapel Hill, Charlotte, Charlottesville, Chicago, Cincinnati, Cleveland, Columbia, Corpus Christi, Dallas, Danville, Dayton, Des Moines, Durham, El Paso, Fargo, Fort Worth, Gainesville, Grand Rapids, Green Bay, Greenville, Hackensack, Hartford, Hershey, Hollywood, Honolulu, Houston, Indianapolis, Jackson, Jacksonville, Kalamazoo, Kansas City, Knoxville, Las Vegas, Lebanon, Lexington, Little Rock, Loma Linda, Long Beach, Louisville, Memphis, Mesa, Miami, Milwaukee, Minneapolis, Morristown, Nashville, New Brunswick, New Haven, New Hyde Park, New Orleans, New York, Norfolk, Oakland, Oak Lawn, Oklahoma City, Omaha, Orange, Orlando, Park Ridge, Paterson, Pensacola, Peoria, Philadelphia, Pittsburgh, Providence, Richmond, Roanoke, Rochester, Sacramento, San Antonio, San Francisco, Scarborough, Seattle, Sioux Falls, Spokane, Springfield, St Louis, St. Petersburg, Syracuse, Tampa, Temple, The Bronx, Toledo, Valhalla, Washington D.C., West Palm Beach, Wilmington, Winston-Salem, Worcester
Age
Up to 365 days
People
153 worldwide
Run by
National Cancer Institute (NCI)
See details and how to joinNCT06317662
Phase 2Taking people
Ruxolitinib Maintenance Post-Hematopoietic Stem Cell Transplant T-Cell Lymphoma
Where
Columbus, Houston
Age
18 years and over
People
44
Run by
Ohio State University Comprehensive Cancer Center
See details and how to joinNCT07356245
Phase 1/2Taking people
CD19/CD22 Bicistronic Chimeric Antigen Receptor (CAR) T Cells in Children and Young Adults With Recurrent or Refractory B Cell Malignancies
Where
Bethesda
Age
3 years to 39 years
People
130
Run by
National Cancer Institute (NCI)
See details and how to joinNCT05442515
Phase 2Taking people
Cord Blood Transplant, Cyclophosphamide, Fludarabine, and Total-Body Irradiation in Treating Patients With High-Risk Hematologic Diseases
Where
Seattle
Age
6 months to 65 years
People
54
Run by
Fred Hutchinson Cancer Center
See details and how to joinNCT06013423
Phase 1/2Taking people
Gene Therapy for CD19-Positive Hematologic Malignancies (SENTRY-CD19)
Where
Chapel Hill, Columbus, Denver, Duarte, Houston, Jacksonville, Los Angeles, Nashville, Portland, Rochester, Valhalla
Age
13 years to 90 years
People
32
Run by
Vironexis Biotherapeutics Inc.
See details and how to joinNCT06533579
Phase 2Taking people
CD22 CAR T-cells to Extend Remission Following Commercial CD19 CAR T-cells in Children, Adolescents, and Adults With Relapsed/Refractory B-cell Acute Lymphoblastic Leukemia
Where
Bethesda
Age
3 years to 65 years
People
20
Run by
National Cancer Institute (NCI)
See details and how to joinNCT07328503
Phase 1Not yet taking people in United States
Metabolically Fit CD19 CAR T Cells With CD34 Selection Markers in Adults With CD19-Positive B-Cell Acute Lymphocytic Leukemia
Where
Charleston
Age
18 years and over
People
18
Run by
Medical University of South Carolina
See details and how to joinNCT07896213
Phase 2Taking people
CMV-MVA Triplex Vaccination in HLA-Matched Related Stem Cell Donors for the Prevention of CMV Infection in Patients Undergoing Hematopoietic Stem Cell Transplant
Where
Atlanta, Boston, Duarte
Age
18 years to 75 years
People
216
Run by
City of Hope Medical Center
See details and how to joinNCT06059391
Phase 1Taking people
A Vaccine (CMV-MVA Triplex Vaccine) for the Enhancement of CMV-Specific Immunity and the Prevention of CMV Viremia in Patients Undergoing Haploidentical Hematopoietic Stem Cell Transplant
Where
Atlanta, Boston, Duarte
Age
18 years to 75 years
People
46
Run by
City of Hope Medical Center
See details and how to joinNCT07020533
Phase 1/2Taking people
Study of AZD3632 Monotherapy or in Combination With Anticancer Agents in Participants With Advanced Haematologic Malignancies With KMT2Ar, NPM1m, or Other Genotypes Associated With HOX Overexpression
Where
Chapel Hill, Decatur, Durham, Houston, New York, Portland
Age
16 years and over
People
85 worldwide
Run by
AstraZeneca
See details and how to joinNCT07155226 · EU 2025-521299-76-00
No phaseNot yet taking people in United States
Weight Gain in Pediatric Leukemia Survivors
Where
St Louis
Age
6 years and over
People
80
Run by
Washington University School of Medicine
See details and how to joinNCT07374315
No phaseNot yet taking people in United States
Real World Asparaginase Therapy Toxicity
Where
Memphis
People
200
Run by
St. Jude Children's Research Hospital
See details and how to joinNCT07008027
No phaseNot yet taking people in United States
Prevention of Oral Mucositis in Adults in With Hematologic Malignancy
Where
Milwaukee, Oak Lawn, Park Ridge
Age
18 years and over
People
206
Run by
Wake Forest University Health Sciences
See details and how to joinNCT07809984
No phaseEnrolling by invitation
Biology Studies of Hematologic Cancers
Where
Bethesda
Age
1 year to 120 years
People
550
Run by
National Cancer Institute (NCI)
See details and how to joinNCT00923442