Alzheimer disease trials in Canada

In Canada 57 Also abroad 815

57 trials · From ClinicalTrials.gov, checked 12 November 2026. Ask the study team whether a trial fits you.

Phase 2Taking people
Cannabidiol Medication Intervention Trial
Where
Calgary, London, Toronto, Whitby
Age
55 years and over
People
40
Run by
Sunnybrook Health Sciences Centre
See details and how to joinNCT06014424
Phase 2Taking people
Levetiracetam for Persons at Risk for Alzheimer's Disease
Where
Toronto
Age
55 years to 85 years
People
40
Run by
Sunnybrook Health Sciences Centre
See details and how to joinNCT07477431
Phase 2/3Taking people
A Study of Potential Disease Modifying Treatments in Individuals at Risk for or With a Type of Early Onset AD Caused by a Genetic Mutation
Where
Québec, Toronto, Vancouver, Verdun
Age
18 years and over
People
280 worldwide
Run by
Washington University School of Medicine
See details and how to joinNCT05552157
Phase 2/3Taking people
A Study of a Potential Disease Modifying Treatment in Individuals at Risk for or With a Type of Early Onset AD Caused by a Genetic Mutation
Where
Québec, Toronto, Vancouver, Verdun
Age
18 years and over
People
280 worldwide
Run by
Washington University School of Medicine
See details and how to joinNCT06647498
No phaseTaking people
Brain Wave Informed Non-invasive Brain Stimulation: Improving Neural Networks of Working Memory in Dementia: a Proof-of-concept Study
Where
Hamilton
Age
55 years and over
People
30
Run by
McMaster University
See details and how to joinNCT07673770
Phase 3Taking people
A Study to Evaluate Safety and Efficacy of KarXT + KarX-EC as a Treatment for Psychosis Associated With Alzheimer's Disease (ADEPT-5)
Where
Montreal, Toronto, Whitby
Age
55 years to 90 years
People
325 worldwide
Run by
Bristol-Myers Squibb
See details and how to joinNCT06947941
No phaseTaking people
The Brain Health PRO Online Risk Factor Reduction Study to Prevent Dementia
Where
Vancouver
Age
50 years to 80 years
People
700
Run by
University of British Columbia
See details and how to joinNCT07364019
No phaseTaking people
Aerobic Exercise for Older Adults at Increased Risk of Alzheimer's Disease and Related Dementias
Where
Calgary
Age
50 years to 80 years
People
264
Run by
University of Calgary
See details and how to joinNCT03035851
No phaseTaking people
Development of a Database to Investigate Digital and Blood-Based Biomarkers and Their Relationship to Tau and Amyloid PET Imaging in Older Participants Who Are Cognitively Normal (CN), Have Mild Cognitive Impairment (MCI), or Have Mild-to-Moderate AD Dementia
Where
Toronto
Age
60 years to 90 years
People
1,200 worldwide
Run by
GAP Innovations, PBC
See details and how to joinNCT06584357
No phaseTaking people
rTMS for Apathy Clinical Trial
Where
Toronto
People
10
Run by
Sunnybrook Health Sciences Centre
See details and how to joinNCT05561205
No phaseTaking people
TACS to Engage Theta-Gamma Coupling and Enhance Working Memory in Patients With MCI (tACS-MCI)
Where
Toronto
Age
60 years and over
People
20
Run by
Centre for Addiction and Mental Health
See details and how to joinNCT06783283
No phaseTaking people
Radialis PET Imager for the Assessment of Neuritic Amyloid Plaque Burden
Where
Toronto
Age
18 years and over
People
160
Run by
University Health Network, Toronto
See details and how to joinNCT06757569
Phase 2Taking people
Open-label Extension Study in Participants With Early Alzheimer's Disease
Where
Greenfield Park, Ottawa, Peterborough, Sherbrooke, Toronto
Age
50 years to 85 years
People
220 worldwide
Run by
GlaxoSmithKline
See details and how to joinNCT07105709
No phaseTaking people
Comprehensive Assessment of Neurodegeneration and Dementia
Where
Calgary, Edmonton, Halifax, Hamilton, London, Montreal, Ottawa, Peterborough, Québec, Sherbrooke, Toronto, Vancouver, Victoria, Waterloo
Age
50 years to 90 years
People
1,573
Run by
McGill University
See details and how to joinNCT03402919
Phase 2Taking people
Daridorexant for Alzheimer Disease Prevention
Where
Montreal
Age
50 years to 90 years
People
240
Run by
Douglas Mental Health University Institute
See details and how to joinNCT07213349
Phase 2Taking people
Combined Brain Stimulation and Methylphenidate Treatment for Apathy in Dementia
Where
Toronto
People
12
Run by
Sunnybrook Health Sciences Centre
See details and how to joinNCT07279740
No phaseTaking people
Infrared Light for Memory Loss in Mild Cognitive Impairment (MCI)
Where
Toronto
Age
50 years and over
People
60
Run by
Unity Health Toronto
See details and how to joinNCT06618807
No phaseTaking people
Longitudinal Study to Investigate Different Transcranial Electrical Stimulation
Where
Winnipeg
Age
50 years to 95 years
People
200
Run by
University of Manitoba
See details and how to joinNCT06877312
No phaseTaking people
Improving Prognostic Confidence in Neurodegenerative Diseases Causing Dementia Using Peripheral Biomarkers and Integrative Modeling
Where
North York, Toronto
Age
30 years to 95 years
People
500
Run by
University Health Network, Toronto
See details and how to joinNCT06529744
No phaseTaking people
Deep TMS for Comorbid Depression and Cognitive Impairment in Older Adults
Where
Toronto
Age
60 years and over
People
28
Run by
Rotman Research Institute at Baycrest
See details and how to joinNCT03665831
No phaseTaking people
dTMS for Subjective Cognitive Decline
Where
Toronto
Age
55 years to 70 years
People
30
Run by
Rotman Research Institute at Baycrest
See details and how to joinNCT06095063
Phase 2Not yet taking people in Canada
Evaluation of the Safety and Efficacy of NeuroEPO in Subjects With Mild to Moderate Alzheimer's Disease
Where
Saskatoon
Age
50 years and over
People
90
Run by
University of Saskatchewan
See details and how to joinNCT07178678
No phaseTaking people
Screening for Anti-amyloid Treatment Eligibility Using Digital Cognition and Blood-based Biomarkers
Where
Greenfield Park
Age
55 years to 90 years
People
500
Run by
MoCA Clinic and Institute
See details and how to joinNCT07041450
No phaseTaking people
Deep Brain Stimulation of the Pedunculopontine Nucleus for Alzheimer's Disease
Where
Toronto
Age
60 years and over
People
6
Run by
University Health Network, Toronto
See details and how to joinNCT06936124
No phaseTaking people
Investigating Genetic Status in Patients Presenting to Clinic
Where
London
Age
18 years and over
People
1,000
Run by
London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
See details and how to joinNCT05911932