Amyloidosis trials in United States

In United States 69 Also abroad 185

30 of 69 trials · From ClinicalTrials.gov, checked 15 November 2026. Ask the study team whether a trial fits you.

No phaseTaking people
Long-term Safety of Eplontersen Treated aTTR Patients and in Liver Transplant and Severely Hepatic Impaired Subpopulations
Where
Los Angeles
Age
18 years and over
People
320 worldwide
Run by
AstraZeneca
See details and how to joinNCT07654855
No phaseCompleted
Multicenter Study for the Validation of an AI-based ECG Platform for Early Cardiac Amyloidosis Diagnosis
Where
Evanston
Age
18 years and over
People
2,200 worldwide
Run by
Idoven 1903 S.L.
See details and how to joinNCT06978660
No phaseNot yet taking people in United States
Southeastern ATTR Amyloidosis Consortium: SEATTRAC Family Registry
Where
Richmond
Age
18 years and over
People
1,000
Run by
Virginia Commonwealth University
See details and how to joinNCT05974644
No phaseNot yet taking people in United States
PET/CT Imaging in Carriers of TTR Mutations
Where
Dallas
Age
30 years to 80 years
People
80
Run by
University of Texas Southwestern Medical Center
See details and how to joinNCT07591038
No phaseTaking people
Tissue, Blood, and Body Fluid Sample Collection From Patients With Hematologic Cancer
Where
Chapel Hill
Age
18 years to 120 years
People
15,000
Run by
UNC Lineberger Comprehensive Cancer Center
See details and how to joinNCT01137643
No phaseTaking people
CCM OPEN HF Registry
Where
Ann Arbor, Boston, Browns Mills, El Paso, Germantown, Hackensack, Haddon Heights, Kansas City, Londonderry, Lynchburg, Mesa, Milwaukee, Minneapolis, Newark, Novi, Oklahoma City, Orlando, Phoenix, Portland, Surprise, Tampa, Tyler, Vancouver, West Reading, Ypsilanti
Age
18 years and over
People
5,500
Run by
Impulse Dynamics
See details and how to joinNCT07112924
No phaseTaking people
Screening for AL Amyloidosis in Smoldering Multiple Myeloma
Where
Birmingham, Boston, Charlotte, Columbus, Dallas, Durham, Los Angeles, New York, Richmond, Salt Lake City, San Francisco, Weston
Age
40 years and over
People
400
Run by
Tufts Medical Center
See details and how to joinNCT06365060
No phaseNot yet taking people in United States
PET Imaging Study Using Evuzamitide to Detect Cardiac Amyloidosis in Patients With Inconclusive Nuclear Scans and Elevated TAD1 Levels
Where
Boston, Dallas, New York
People
25
Run by
Lorena Saelices
See details and how to joinNCT07538518
No phaseTaking people
ConTTRibute: A Global Observational Study of Patients With Transthyretin (TTR)-Mediated Amyloidosis (ATTR Amyloidosis)
Where
Austin, Baltimore, Boston, Columbus, Durham, Houston, Iowa City, Jacksonville, Kansas City, La Jolla, Los Angeles, New York, Philadelphia
People
1,500 worldwide
Run by
Alnylam Pharmaceuticals
See details and how to joinNCT04561518
No phaseTaking people
DemonsTTRate: A Global, Observational, Multicenter, Long-term Study of Patients With ATTR-CM in a Real-World Setting
Where
Beverly Hills, Boston, Charlotte, Dallas, Honolulu, Kansas City, La Jolla, Memphis, Naples, New Brunswick, Philadelphia, St Louis, Tucson
Age
18 years and over
People
2,000 worldwide
Run by
Alnylam Pharmaceuticals
See details and how to joinNCT07358078
No phaseTaking people
Patisiran-Lipid Nanoparticle (LNP) Pregnancy Surveillance Program
Where
Iowa City
People
10 worldwide
Run by
Alnylam Pharmaceuticals
See details and how to joinNCT05040373
No phaseTaking people
SMS-Based Remote Symptom Monitoring for Patients With Plasma Cell Disorders
Where
Rochester
Age
18 years and over
People
150
Run by
Mayo Clinic
See details and how to joinNCT07850284
No phaseTaking people
Non-interventional Study of Patients With Transthyretin (ATTR) Amyloidosis
Where
Baltimore, Boston, Chicago, Dallas, Danville, Durham, Germantown, Greenville, Houston, Indianapolis, Kansas City, La Jolla, Los Angeles, Manhasset, Milwaukee, Nashville, New Brunswick, New Haven, New York, Philadelphia, Portland, Richmond, Rochester, San Francisco, Seattle, St Louis, Washington D.C.
Age
18 years to 130 years
People
1,850 worldwide
Run by
AstraZeneca
See details and how to joinNCT06465810
No phaseCompleted
OverTTuRe: Characteristics, Treatment Patterns and Outcomes of Patients With ATTR Amyloidosis
Where
Eden Prairie
People
52,121 worldwide
Run by
AstraZeneca
See details and how to joinNCT06355934
No phaseTaking people
Subclinical Transthyretin Cardiac Amyloidosis in V122I TTR Carriers
Where
Cleveland, Dallas, New York
Age
30 years to 80 years
People
500
Run by
University of Texas Southwestern Medical Center
See details and how to joinNCT05489549
No phaseNot yet taking people in United States
Retinal Fundus Imaging and OCT Imaging for Ocular Detection of ATTR-CM
Where
Boston, Chicago, Germantown, Jacksonville, Palo Alto, Portland
Age
18 years and over
People
500 worldwide
Run by
AstraZeneca
See details and how to joinNCT07690436
No phaseEnrolling by invitation
Prospective Evaluation of Artificial Intelligence-enabled Screening for Transthyretin Amyloid Cardiomyopathy (ATTR-CM)
Where
New Haven
Age
18 years and over
People
150
Run by
Yale University
See details and how to joinNCT07398950
No phaseTaking people
Cardiovascular Multimodality Imaging Study
Where
The Bronx
Age
18 years and over
People
10,000
Run by
Montefiore Medical Center
See details and how to joinNCT06610019
No phaseTaking people
Artificial Intelligence Guided Echocardiographic Screening of Rare Diseases (EchoNet-Screening)
Where
Los Angeles
Age
18 years and over
People
300
Run by
Cedars-Sinai Medical Center
See details and how to joinNCT05139797
No phaseTaking people
Registry of Older Patients With Cancer
Where
Boone, Chapel Hill, Greenville, Hendersonville, Morehead City, New Bern, Raleigh
Age
65 years and over
People
3,000
Run by
UNC Lineberger Comprehensive Cancer Center
See details and how to joinNCT01137825
No phaseTaking people
Analysis of Lumbar Spine Stenosis Specimens for Identification of Transthyretin Cardiac Amyloidosis
Where
Beverly Hills, Boston, Cleveland, New York, Rochester
Age
50 years and over
People
1,663
Run by
Columbia University
See details and how to joinNCT06034405
No phaseTaking people
A Study Of Deep Learning For Echo Analysis, Tracking, And Evaluation
Where
Rochester
Age
18 years and over
People
10,040,000
Run by
Mayo Clinic
See details and how to joinNCT07308704
No phaseTaking people
Ohio State University Multiple Myeloma and Amyloidosis Data Registry and Sample Resource
Where
Columbus
Age
18 years and over
People
5,000
Run by
Ohio State University Comprehensive Cancer Center
See details and how to joinNCT01408225
No phaseTaking people
Determining the Association of TTR Stabilizing Therapy With Circulating TTR Amyloid Aggregates Over Time in Patients With ATTR-CM: Longitudinal Biomarker Study
Where
Dallas
Age
30 years to 80 years
People
50
Run by
University of Texas Southwestern Medical Center
See details and how to joinNCT07196839
No phaseTaking people
A Study Of Myocardial Stiffness In Amyloidosis With Magnetic Resonance Elastography
Where
Rochester
Age
20 years and over
People
20
Run by
Mayo Clinic
See details and how to joinNCT07216469