Amyloidosis trials in United States

In United States 69 Also abroad 184

69 trials · From ClinicalTrials.gov, checked 12 November 2026. Ask the study team whether a trial fits you.

Phase 2Taking people
DapagliFLOzin in Renal AL Amyloidosis (FLORAL)
Where
Detroit
Age
18 years and over
People
20
Run by
Barbara Ann Karmanos Cancer Institute
See details and how to joinNCT06420167
No phaseTaking people
Analysis of Lumbar Spine Stenosis Specimens for Identification of Transthyretin Cardiac Amyloidosis
Where
Beverly Hills, Boston, Cleveland, New York, Rochester
Age
50 years and over
People
1,663
Run by
Columbia University
See details and how to joinNCT06034405
Phase 1Taking people
Repeat PET/CT Imaging in People With CAPS and Anakinra-Induced Amyloidosis Using an Amyloid-Reactive Peptide to Measure Changes in Organ-Specific Amyloid Load
Where
Bethesda
Age
18 years to 120 years
People
30
Run by
National Institute of Allergy and Infectious Diseases (NIAID)
See details and how to joinNCT06974877
Phase 1/2Taking people
A Study to Assess Change in Disease Activity and Adverse Events (AE)s in Adult Participants With Immunoglobulin Light Chain (AL) Amyloidosis Receiving Etentamig (ABBV-383) as an Intravenous (IV) Infusion
Where
Boston, Charlotte, Miami, Milwaukee, Nashville, New York, Portland, Rochester, Seattle, Winston-Salem
Age
18 years and over
People
76 worldwide
Run by
AbbVie
See details and how to joinNCT06158854 · EU 2023-503429-20-00
Phase 3Taking people
Comparing Dara-VCD Chemotherapy Plus Stem Cell Transplant to Dara-VCD Chemotherapy Alone for People Who Have Newly Diagnosed AL Amyloidosis
Where
Ankeny, Ann Arbor, Atlanta, Aurora, Aventura, Baytown, Bellevue, Bethesda, Boston, Brownstown, Charlotte, Chicago, City of Saint Peters, Cleveland, Clinton Township, Clive, Collierville, Columbus, Commack, Coon Rapids, Coral Gables, Coral Springs, Creve Coeur, Cypress, Danville, Dearborn, Deerfield Beach, Derby, Des Moines, Detroit, Duarte, Durham, Edina, Effingham, Farmington Hills, Goodyear, Green Bay, Greenwich, Guilford, Harrison, Hartford, Hollywood, Houston, Huntersville, Irvine, Jackson, Kansas City, La Crosse, Lansing, Madison, Mattoon, Maywood, Memphis, Miami, Middletown, Milwaukee, Minneapolis, Montvale, Mooresville, Nassau Bay, Newberg, New Haven, New York, North Haven, North Miami, Novi, Oconto Falls, Omaha, Orange, Oregon City, Oxford, Philadelphia, Plantation, Portland, Rochester, Saint Louis Park, Saint Paul, Sheboygan, Southhaven, Stamford, St Louis, Sturgeon Bay, Sugar Land, The Woodlands, Trumbull, Tucson, Urbana, Washington D.C., Waukee, West Bloomfield, Westwood, Wilkes-Barre, Winston-Salem, Wyandotte
Age
18 years and over
People
338
Run by
SWOG Cancer Research Network
See details and how to joinNCT06022939
Phase 3Enrolling by invitation
An Extension Study to Assess Long-Term Safety of Eplontersen in Adults With Transthyretin-Mediated Amyloid Cardiomyopathy (ATTR-CM)
Where
Atlanta, Aurora, Baltimore, Beverly Hills, Boston, Chapel Hill, Charleston, Chicago, Cincinnati, Cleveland, Columbus, Dallas, Detroit, Durham, Fayetteville, Houston, Indianapolis, Kansas City, La Jolla, Lancaster, Madison, Maywood, Minneapolis, Nashville, New York, Philadelphia, Portland, Richmond, Rochester, Salt Lake City, San Francisco, Scottsdale, Seattle, Stanford, St Louis, Washington D.C., Weston
Age
18 years and over
People
1,400 worldwide
Run by
Ionis Pharmaceuticals, Inc.
See details and how to joinNCT05667493
No phaseTaking people
A Study Of Deep Learning For Echo Analysis, Tracking, And Evaluation
Where
Rochester
Age
18 years and over
People
10,040,000
Run by
Mayo Clinic
See details and how to joinNCT07308704
Phase 2Taking people
Characterizing Iodine-124 Evuzumitide (AT-01) in Systemic Amyloidosis
Where
Portland
Age
40 years to 90 years
People
150
Run by
Oregon Health and Science University
See details and how to joinNCT05758493
No phaseTaking people
Ohio State University Multiple Myeloma and Amyloidosis Data Registry and Sample Resource
Where
Columbus
Age
18 years and over
People
5,000
Run by
Ohio State University Comprehensive Cancer Center
See details and how to joinNCT01408225
No phaseTaking people
Determining the Association of TTR Stabilizing Therapy With Circulating TTR Amyloid Aggregates Over Time in Patients With ATTR-CM: Longitudinal Biomarker Study
Where
Dallas
Age
30 years to 80 years
People
50
Run by
University of Texas Southwestern Medical Center
See details and how to joinNCT07196839
Phase 2Taking people
Minimal Residual Disease Response-adapted Deferral of Transplant in Dysproteinemia (MILESTONE)
Where
Birmingham
Age
18 years and over
People
40
Run by
University of Alabama at Birmingham
See details and how to joinNCT04991103
No phaseTaking people
A Study Of Myocardial Stiffness In Amyloidosis With Magnetic Resonance Elastography
Where
Rochester
Age
20 years and over
People
20
Run by
Mayo Clinic
See details and how to joinNCT07216469
No phaseTaking people
A Study Of MCG In Cardiac Amyloidosis
Where
Rochester
Age
18 years and over
People
500
Run by
Mayo Clinic
See details and how to joinNCT07218705
No phaseTaking people
Cancer and Aging Resilience Evaluation in Older Adults With Hematologic Malignancies: The CARE-Heme Registry
Where
Birmingham
Age
50 years and over
People
5,000
Run by
University of Alabama at Birmingham
See details and how to joinNCT05556928
No phaseTaking people
Collection of Samples and Clinical Data From Patients With Amyloid Diseases
Where
Boston
Age
18 years and over
People
10,000
Run by
Boston Medical Center
See details and how to joinNCT00898235
No phaseTaking people
Registry for Adults With Plasma Cell Disorders (PCD's)
Where
Chapel Hill
Age
18 years and over
People
2,000
Run by
UNC Lineberger Comprehensive Cancer Center
See details and how to joinNCT03717844
No phaseTaking people
Molecular Imaging of Primary Amyloid Cardiomyopathy
Where
Boston
Age
18 years to 99 years
People
171
Run by
Brigham and Women's Hospital
See details and how to joinNCT02641145
No phaseTaking people
US Benchmarking Clinical Study
Where
Boston
Age
60 years and over
People
150
Run by
eMyosound SAS
See details and how to joinNCT07215715
No phaseTaking people
Exercise Training in Transthyretin Cardiac Amyloidosis
Where
Boston
Age
60 years to 90 years
People
40
Run by
Brigham and Women's Hospital
See details and how to joinNCT05797857