Brain metastases trials in China

In China 56 Also abroad 221

56 trials · From ClinicalTrials.gov, checked 15 November 2026. Ask the study team whether a trial fits you.

Phase 1/2Taking people
A Study to Evaluate Safety and Efficacy of WSD0922-FU Combo With Osimertinib for NSCLC
Where
Fuzhou, Shanghai, Tianjin
Age
18 years and over
People
48
Run by
Wayshine Biopharm, Inc.
See details and how to joinNCT07206498
Phase 2Taking people
BrAin Metastasis in tripLe Negateive Breast Cancer: IvoneScimab and Trop2 ADC
Where
Shanghai
Age
18 years to 70 years
People
39
Run by
Fudan University
See details and how to joinNCT06793332
No phaseTaking people
ePRO in Advanced Lung Cancer: Emotional Distress, Symptom Burden, Brain Metastasis
Where
Hubei
Age
18 years and over
People
200
Run by
Qian Chu
See details and how to joinNCT07912190
Phase 1/2Taking people
Phase I/II Study of Intrathecal/Ommaya T-DXd in HER2-Expressing Breast Cancer With Leptomeningeal/Brain Metastases
Where
Shanghai
Age
18 years and over
People
139
Run by
Fudan University
See details and how to joinNCT07134153
Phase 1/2Taking people
Phase 1/2 Trial of S241656 in Selected RAS/MAPK Mutation- Positive Malignancies
Where
Beijing, Jinan, Shanghai, Suzhou
Age
18 years and over
People
554 worldwide
Run by
Institut de Recherches Internationales Servier
See details and how to joinNCT05786924 · EU 2025-523474-16-00
Phase 2Taking people
A Single-arm, Prospective Phase Ⅱ Clinical Study of Utidelone Combined With Capecitabine in the Treatment of Active Brain Metastasis of TNBC
Where
Zhengzhou
Age
18 years and over
People
48
Run by
Henan Cancer Hospital
See details and how to joinNCT06598046
Phase 2Taking people
Trastuzumab Rezetecan Combined With Radiotherapy Versus Trastuzumab Rezetecan in the Treatment of HER2-positive Advanced Breast Cancer With Brain Metastases
Where
Zhengzhou
Age
18 years and over
People
224
Run by
Henan Cancer Hospital
See details and how to joinNCT07100600
Phase 3Taking people
SRS/SRT/Hypo-RT Versus HA-WBRT for No More Than 10 Brain Metastases in SCLC
Where
Beijing
Age
18 years to 80 years
People
340
Run by
Cancer Institute and Hospital, Chinese Academy of Medical Sciences
See details and how to joinNCT06457906
Phase 2Taking people
T-DXd With or Without Neratinib for HER2 Positive Breast Cancer With Brain Metastasis
Where
Shanghai
Age
18 years to 70 years
People
202
Run by
Fudan University
See details and how to joinNCT07152782
Phase 2Taking people
T-DXd With or Without Bevacizumab for HER2-low Breast Cancer With Brain Metastasis
Where
Shanghai
Age
18 years to 70 years
People
140
Run by
Fudan University
See details and how to joinNCT07150208
Phase 2Taking people
Study of Radiotherapy Combined With Cisplatin/Carboplatin, Adebrelimab and Bevacizumab in the Treatment of TNBC-BM.
Where
Shanghai
Age
18 years to 70 years
People
58
Run by
Fudan University
See details and how to joinNCT07638852
Phase 2Taking people
TY-9591 in the Patients With EGFR Mutations in Advanced NSCLC With Brain Metastases
Where
Beijing
Age
18 years to 80 years
People
420
Run by
TYK Medicines, Inc
See details and how to joinNCT05948813
Phase 3Taking people
A Study Evaluating Furmonertinib Plus Platinum-based Doublet Chemotherapy Versus Osimertinib in Patients With Epidermal Growth Factor Receptor (EGFR) Sensitizing Mutation-Positive Non-squamous Non-Small Cell Lung Cancer (NSCLC) and Brain Metastases
Where
Guangdong
Age
18 years and over
People
380
Run by
Allist Pharmaceuticals, Inc.
See details and how to joinNCT06970639
Phase 2Not yet taking people in China
Culmerciclib Plus Anlotinib and Endocrine Therapy for HR-Positive/HER2-Negative Metastatic Breast Cancer With Brain Metastases
Where
Anyang, Chengdu, Dalian, Guangzhou, Hangzhou, Nanchang, Nanjing, Shijiazhuang, Zhengzhou
Age
18 years to 80 years
People
40
Run by
Sun Yat-sen University
See details and how to joinNCT07745257
Early phase 1Not yet taking people in China
QH101 Cell Injection in Patients With Brain, Brain (Spinal) Meninges, and Spinal Cord Metastatic Malignant Solid Tumors
Where
Beijing
Age
18 years and over
People
7
Run by
Cancer Institute and Hospital, Chinese Academy of Medical Sciences
See details and how to joinNCT07656103
No phaseTaking people
A Prospective, Multicenter, Observational Cohort Study to Evaluate the Efficacy and Safety of a Novel Anti-tumor Drug as a Radiosensitizer in Patients With Advanced Breast Cancer Brain Metastasis.
Where
Beijing
Age
18 years and over
People
100
Run by
Cancer Institute and Hospital, Chinese Academy of Medical Sciences
See details and how to joinNCT06839547
Phase 2Taking people
Evaluating the Efficacy and Safety of PD-L1 Monoclonal Antibody Combined With VEX Metronomic Chemotherapy and Concurrent or Delayed Radiotherapy in Patients With Advanced HER2-Negative Breast Cancer With Brain Metastasis
Where
Beijing
Age
18 years and over
People
102
Run by
Cancer Institute and Hospital, Chinese Academy of Medical Sciences
See details and how to joinNCT06839560
No phaseNot yet taking people in China
Impact of Radiotherapy-Immunotherapy Timing in NSCLC Brain Metastases
Where
Changsha
Age
18 years and over
People
150
Run by
Xiangya Hospital of Central South University
See details and how to joinNCT07638709
Phase 2Taking people
Sac-TMT Combined With Bevacizumab in TNBC With Brain Metastases
Where
Shanghai
Age
18 years and over
People
24
Run by
Fudan University
See details and how to joinNCT07623577
Phase 2Taking people
Efficacy and Safety of SPH4336 in Combination With Endocrine Therapy in Breast Cancer Patients With Brain Metastases.
Where
Anyang, Beijing, Bengbu, Changchun, Chongqing, Guangzhou, Hangzhou, Harbin, Hefei, Liuzhou, Luoyang, Nanjing, Nanning, Neijiang, Shijiazhuang, Tianjin, Ürümqi, Wuhan, Xi'an, Xiangyang, Yinchuan, Zhengzhou
Age
18 years to 75 years
People
52
Run by
Shanghai Pharmaceuticals Holding Co., Ltd
See details and how to joinNCT05872347
Phase 2Not yet taking people in China
Brain Radiotherapy Combined With Dalpiciclib and Endocrine Therapy in HR-Positive/HER2-Negative Advanced Breast Cancer With Brain Metastases
Where
Guangzhou
Age
18 years to 75 years
People
46
Run by
Nanfang Hospital, Southern Medical University
See details and how to joinNCT07539753
No phaseTaking people
NK Cell Therapy for Malignant Solid Brain Tumors
Where
Beijing, Qinhuangdao, Zhengzhou
Age
18 years to 70 years
People
27
Run by
Peking University Third Hospital
See details and how to joinNCT07552233
Phase 2/3Not yet taking people in China
Comparison of the Therapeutic Effects of Methylprednisolone and Dexamethasone on Peritumoral Edema During Radiotherapy for Brain Metastases:
Where
Haikou
Age
18 years to 75 years
People
400
Run by
The Second Affiliated Hospital of Hainan Medical University
See details and how to joinNCT07542288
Phase 3Taking people
Bevacizumab Plus FSRT Versus Hippocampus-Avoidant WBRT in Lung Adenocarcinoma With Extensive Brain Metastases
Where
Chongqing, Guangzhou
Age
18 years and over
People
220
Run by
Sun Yat-sen University
See details and how to joinNCT07481786
Phase 2Taking people
Study of SHR-A1811 in HER2-expression Advanced Breast Cancer With Brain Metastases
Where
Zhengzhou
Age
18 years to 75 years
People
150
Run by
Henan Cancer Hospital
See details and how to joinNCT05769010