Childhood cancers trials in Canada

In Canada 154 Also abroad 2481

154 trials · From ClinicalTrials.gov, checked 13 November 2026. Ask the study team whether a trial fits you.

Phase 3Taking people
A Study Comparing Higher Dose Chemotherapy Over a Shorter Amount of Time to Lower Dose Chemotherapy Plus Maintenance Over a Longer Amount of Time in Patients With Newly Diagnosed Intermediate-Risk Rhabdomyosarcoma (IR RMS)
Where
Montreal
Age
Up to 50 years
People
342 worldwide
Run by
Children's Oncology Group
See details and how to joinNCT07466316
Phase 1/2Taking people
A Study of REC-1245 in Participants With Unresectable, Locally Advanced, or Metastatic Cancer
Where
Québec, Toronto
Age
12 years and over
People
170 worldwide
Run by
Recursion Pharmaceuticals Inc.
See details and how to joinNCT06678659
Phase 2Taking people
DFMO as Maintenance Therapy for Molecular High/Very High Risk and Relapsed Medulloblastoma
Where
Québec
Age
Up to 21 years
People
118 worldwide
Run by
Giselle Sholler
See details and how to joinNCT04696029
Phase 2Taking people
Naxitamab Added to Induction for Newly Diagnosed High-Risk Neuroblastoma
Where
Montreal, Québec, Sherbrooke
Age
12 months to 21 years
People
93 worldwide
Run by
Giselle Sholler
See details and how to joinNCT05489887 · EU 2025-524140-35-00
Phase 1Enrolling by invitation
Adoptive Cell Therapy Long-term Follow-up (LTFU) Study
Where
Montreal, Toronto
People
250 worldwide
Run by
USWM CT, LLC
See details and how to joinNCT03391778
Phase 4Taking people
A Study of Toripalimab in Combination With Cisplatin and Gemcitabine in Participants With Recurrent Metastatic Nasopharyngeal Cancer
Where
Toronto
Age
12 years and over
People
100 worldwide
Run by
Coherus Oncology, Inc.
See details and how to joinNCT06457503
Phase 2Taking people
A Study to Assess the Efficacy and Safety of FORE8394 in Participants With Cancer Harboring BRAF Alterations
Where
Montreal, Toronto
Age
8 years and over
People
254 worldwide
Run by
Fore Biotherapeutics
See details and how to joinNCT05503797 · EU 2024-513578-23-00
Phase 3Taking people
Brentuximab Vedotin in Early Stage Hodgkin Lymphoma
Where
Halifax, Hamilton, Ottawa, Saint John, Toronto, Vancouver, Winnipeg
Age
16 years to 69 years
People
1,042 worldwide
Run by
University College, London
See details and how to joinNCT04685616 · EU 2022-500031-37-00
No phaseTaking people
Enhancing the Patient Journey to Clinical Trial Enrolment With Navigation to Optimize Accrual
Where
Thunder Bay, Windsor
People
300
Run by
Windsor Regional Hospital
See details and how to joinNCT06905002
Early phase 1Taking people
Lorlatinib for Newly-Diagnosed High-Grade Glioma With ROS or ALK Fusion
Where
Montreal, Toronto
Age
1 year to 21 years
People
15 worldwide
Run by
Nationwide Children's Hospital
See details and how to joinNCT06333899
No phaseTaking people
Childhood Cancer Survivor Study
Where
Toronto
People
50,000 worldwide
Run by
St. Jude Children's Research Hospital
See details and how to joinNCT01120353
Phase 1/2Taking people
CANnabinoids in Pediatric ONCology
Where
Halifax, Toronto, Vancouver
Age
4 years to 18 years
People
60
Run by
University of Manitoba
See details and how to joinNCT05754840
No phaseTaking people
Blastic Plasmacytoid Dendritic Cell Neoplasm (BPDCN) International Registry
Where
Calgary, Ottawa
People
200 worldwide
Run by
Immune Oncology Research Institute
See details and how to joinNCT05430971
Phase 2Taking people
Study of Ribociclib and Everolimus in HGG and DIPG or Ribociclib and Temozolomide in DHG, H3G34-mutant
Where
Montreal, Toronto
Age
12 months to 39 years
People
120 worldwide
Run by
Nationwide Children's Hospital
See details and how to joinNCT05843253
Phase 1/2Taking people
A Study of Repotrectinib (TPX-0005) in Patients With Advanced Solid Tumors Harboring ALK, ROS1, or NTRK1-3 Rearrangements
Where
Edmonton, Ontario, Ottawa, Toronto, Vancouver
Age
12 years and over
People
500 worldwide
Run by
Turning Point Therapeutics, Inc.
See details and how to joinNCT03093116 · EU 2024-512606-25-00
Phase 2Taking people
68Ga-DOTATATE Neuroblastoma Imaging Pilot
Where
Montreal, Sherbrooke
Age
Up to 21 years
People
20
Run by
Centre de recherche du Centre hospitalier universitaire de Sherbrooke
See details and how to joinNCT04559217
Phase 1/2Taking people
Study of Onivyde With Talazoparib or Temozolomide in Children With Recurrent Solid Tumors and Ewing Sarcoma
Where
Montreal, Toronto, Vancouver
Age
12 months to 30 years
People
90 worldwide
Run by
St. Jude Children's Research Hospital
See details and how to joinNCT04901702
No phaseTaking people
Effects of Dexrazoxane Hydrochloride on Biomarkers Associated With Cardiomyopathy and Heart Failure After Cancer Treatment
Where
Calgary, Hamilton, Montreal, Ottawa, Québec, Toronto
People
420 worldwide
Run by
Children's Oncology Group
See details and how to joinNCT01790152
Phase 2Taking people
68Ga-HA-DOTATATE Imaging of Suspected Somatostatin Receptor Positive Tumors
Where
Edmonton
People
600
Run by
University of Alberta
See details and how to joinNCT04888481
Phase 2Taking people
Liquid-biopsy Informed Platform Trial to Evaluate CDK4/6-inhibitor Resistant ER+/HER2- Metastatic Breast Cancer
Where
Calgary, Halifax, Hamilton, Kelowna, Kingston, Montreal, Ottawa, Toronto, Vancouver
People
484
Run by
Canadian Cancer Trials Group
See details and how to joinNCT05601440
Phase 1Enrolling by invitation
Molecular-Functional Imaging of Hypoxia in Childhood Sarcomas
Where
Toronto
Age
6 years to 18 years
People
18
Run by
The Hospital for Sick Children
See details and how to joinNCT03054792
Phase 2Taking people
ACTEMRA® for the Treatment of Pediatric Adamantinomatous Craniopharyngioma
Where
Edmonton, Montreal, Toronto
Age
1 year to 39 years
People
30 worldwide
Run by
Nationwide Children's Hospital
See details and how to joinNCT05233397
No phaseTaking people
Retinoblastoma Patient Clinical Database and Tissue Repository
Where
Toronto
Age
0 years to 18 years
People
800 worldwide
Run by
Children's Hospital Los Angeles
See details and how to joinNCT04959097
Phase 3Taking people
ONC201 in H3 K27M-mutant Diffuse Glioma Following Radiotherapy (the ACTION Study)
Where
Calgary, London, Montreal, Ottawa, Toronto, Vancouver
People
510 worldwide
Run by
Jazz Pharmaceuticals
See details and how to joinNCT05580562 · EU 2022-502051-56-00
No phaseTaking people
Hypersight and Ethos In Pediatric Radiotherapy
Where
Toronto
Age
Up to 18 years
People
20
Run by
University Health Network, Toronto
See details and how to joinNCT07528547