COPD trials in Germany

In Germany 33 Also abroad 559

33 trials · From ClinicalTrials.gov and EU CTIS (euclinicaltrials.eu), checked 11 November 2026. Ask the study team whether a trial fits you.

Phase 2Taking people
A Study of Brenipatide (LY3537031) in Adult Participants With Moderate-to-Severe Chronic Obstructive Pulmonary Disease (COPD)
Where
Frankfurt, Frankfurt am Main, Hamburg, Landsberg Am Lech, Leipzig, Mainz, Rheine
Age
40 years to 75 years
People
606 worldwide
Run by
Eli Lilly and Company
See details and how to joinNCT07759245 · EU 2026-525480-41-00
Phase 3Taking people
A Non-inferiority Pharmacokinetic and Safety/Tolerability Study of Two Different Doses of Weekly SC Alpha1-PI 15% Compared With Corresponding Standard IV Alpha1-PI in Participants With Alpha1-Antitrypsin Deficiency (AATD)
Where
Freiburg im Breisgau
Age
18 years to 80 years
People
40 worldwide
Run by
Grifols Therapeutics LLC
See details and how to joinNCT07555483 · EU 2025-522792-29-00
Phase 2Taking people
A Study to Investigate the Effect of AZD6793 in Participants With Moderate to Very Severe Chronic Obstructive Pulmonary Disease
Where
Ahrensburg, Bendorf, Berlin, Darmstadt, Halle, Hanover, Landsberg, Leipzig, Lübeck, Marburg, Obertshausen, Rosenheim, Schleswig, Wiesbaden, Witten
Age
40 years and over
People
987 worldwide
Run by
AstraZeneca
See details and how to joinNCT07082738
Phase 3Taking people
Efficacy, Safety, and Tolerability Study of Lunsekimig Compared With Placebo in Adult Participants With Inadequately Controlled Chronic Obstructive Pulmonary Disease (COPD), Characterized by an Eosinophilic Phenotype
Where
Bamberg, Berlin, Bonn, Landsberg am Lech, Peine, Witten
Age
40 years to 80 years
People
942 worldwide
Run by
Sanofi
See details and how to joinNCT07190222 · EU 2024-518213-25-00
Phase 2/3Taking people
A Study to Learn About the Study Medicine Called PF-07275315 in People With Moderate to Severe Chronic Obstructive Pulmonary Disease
Where
Ahrensburg, Bendorf, Berlin, Delitzsch, Essen, Frankfurt am Main, Leipzig
Age
35 years to 80 years
People
1,156 worldwide
Run by
Pfizer
See details and how to joinNCT07363694 · EU 2024-518587-12-00
No phaseNot yet taking people in Germany
Upper Airway Morphology and Physiology During Graded Positive Pressure and Nasal High Flow: An MRI Study
Where
Dortmund
Age
18 years and over
People
20
Run by
Klinikum Dortmund Wirbelsäulenchirurgie
See details and how to joinNCT07886502
Phase 4Taking people
A Study to Investigate Airway Inflammation With Dupilumab Subcutaneously in Participants Aged ≥40 to ≤85 Years With Chronic Obstructive Pulmonary Disease.
Where
Berlin, Mainz
Age
40 years to 85 years
People
218 worldwide
Run by
Sanofi
See details and how to joinNCT07053423
No phaseTaking people
Bronchoscopic RElease of Air Trapped in Hyperinflated Emphysematous Lung - Study 3
Where
Heidelberg
Age
40 years to 84 years
People
250 worldwide
Run by
Apreo Health, Inc.
See details and how to joinNCT06891755
Phase 3Taking people
Efficacy, Safety, and Tolerability Study of Lunsekimig Compared With Placebo in Adult Participants With Inadequately Controlled Chronic Obstructive Pulmonary Disease (COPD) Characterized by an Eosinophilic Phenotype
Where
Ahrensburg, Augsburg, Bendorf, Berlin, Darmstadt, Frankfurt, Frankfurt am Main, Hamburg, Leipzig, Lübeck, Mainz, Munich
Age
40 years to 80 years
People
942 worldwide
Run by
Sanofi
See details and how to joinNCT07190209 · EU 2024-518016-39-00
No phaseTaking people
Induced Sputum Collection in COPD Patients With and Without a Vibroacoustic Device
Where
Hanover
Age
40 years and over
People
20
Run by
Fraunhofer-Institute of Toxicology and Experimental Medicine
See details and how to joinNCT07751705
Phase 2Not yet taking people in Germany
A Randomized, Double-Blind, Placebo-controlled, Parallel Arm, 52-week Study to Assess Efficacy, Safety, Tolerability, and Pharmacokinetics of Two Doses of EXPD-101 in Participants with COPD
Where
Berlin, Cologne, Essen, Frankfurt Am Main, Hamburg
Age
18 years and over
People
183 worldwide
Run by
Expedition Therapeutics Inc.
See details and how to join2026-525216-34-00 · EU 2026-525216-34-00
Phase 3Taking people
Depemokimab as an Extended Treatment Duration Biologic in Adults With Chronic Obstructive Pulmonary Disease (COPD) and Type 2 Inflammation
Where
Ahrensburg, Bad Berka, Berlin, Bonn, Cologne, Donaustauf, Essen, Frankfurt, Frankfurt am Main, Giessen, Kiel, Loewenstein, Mainz, München, Peine, Wiesbaden, Wuerzburg, Wuppertal
Age
40 years to 80 years
People
981 worldwide
Run by
GlaxoSmithKline
See details and how to joinNCT06959095 · EU 2024-520418-22-00
Phase 3Taking people
Depemokimab as an Extended Treatment Duration Biologic in Adults With Chronic Obstructive Pulmonary Disease (COPD) and Type 2 Inflammation (ENDURA-2)
Where
Bendorf, Berlin, Darmstadt, Essen, Fürstenwalde, Geesthacht, Giessen, Halle, Homburg, Immenhausen, Leipzig, Luebeck, München, Offenbach Am Main, Rheine, Schleswig
Age
40 years to 80 years
People
961 worldwide
Run by
GlaxoSmithKline
See details and how to joinNCT06961214 · EU 2024-520417-41-00
Phase 3Taking people
A Study Evaluating the Efficacy of Budesonide, Glycopyrronium and Formoterol Fumarate Metered Dosed Inhaler on Cardiopulmonary Outcomes in Chronic Obstructive Pulmonary Disease
Where
Ahrensburg, Augsburg, Bamberg, Berlin, Cottbus, Darmstadt, Essen, Frankfurt am Main, Hamburg, Hannover, Hanover, Ibbenbüren, Landsberg Am Lech, Leipzig, Luebeck, Mainz, Marburg, Moers, Munich, Offenbach Am Main, Peine, Rheine, Riesa, Rosenheim, Solingen, Wallerfing, Wermsdorf, Wiesbaden, Witten
Age
40 years to 80 years
People
5,250 worldwide
Run by
AstraZeneca
See details and how to joinNCT06283966 · EU 2023-507407-59-00
Phase 4Taking people
A Study to Investigate the Effect of Budesonide/Glycopyrronium/Formoterol Fumarate Metered Dose Inhaler (BGF MDI) Compared With Placebo MDI on Heart and Lung Function in Participants With Chronic Obstructive Pulmonary Disease (COPD) and Hyperinflation
Where
Ahrensburg, Berlin, Frankfurt am Main, Hanover
Age
40 years to 80 years
People
56 worldwide
Run by
AstraZeneca
See details and how to joinNCT07073950 · EU 2025-521987-37-00
No phaseTaking people
An Evaluation of the AeriSeal System for CONVERTing Collateral Ventilation Status in Patients With Severe Emphysema
Where
Essen, Halle, Hamburg, Heidelberg, Hemer
Age
40 years to 80 years
People
200 worldwide
Run by
Pulmonx Corporation
See details and how to joinNCT06035120
Phase 3Taking people
A Study to Investigate the Efficacy and Safety of Tezepelumab in Adult Participants With Moderate to Very Severe COPD (D5241C00006)
Where
Bendorf, Berlin, Hanover, Immenhausen, Marburg, Rosenheim, Wiesbaden
Age
40 years to 80 years
People
990 worldwide
Run by
AstraZeneca
See details and how to joinNCT06883305 · EU 2024-517458-90-00
Phase 1Taking people
A Study to Evaluate the Safety and Activity of an Inhaled Investigational Drug (RO7616605) in Healthy Volunteers and Participants With COPD
Where
Berlin, Hanover
Age
18 years and over
People
104
Run by
Genentech Inc.
See details and how to join2025-525042-22-00 · EU 2025-525042-22-00
Phase 2Taking people
A study to investigate the effect of AZD6793 in participants with moderate to very severe chronic obstructive pulmonary disease
Where
Bendorf, Berlin, Darmstadt, Halle, Hanover, Landsberg Am Lech, Leipzig, Luebeck, Marburg, Obertshausen, Rosenheim, Schleswig, Wiesbaden, Witten
Age
18 years and over
People
307 worldwide
Run by
AstraZeneca AB
See details and how to join2025-520473-40-00 · EU 2025-520473-40-00
Phase 3Taking people
eValuating the Efficacy and Safety of InitiatinG depemokImab earLy therApy iN Chronic Obstructive Pulmonary Disorder (COPD) With Type 2 Inflammation
Where
Ahrensburg, Bendorf, Berlin, Bonn, Essen, Frankfurt, Frankfurt am Main, Hamburg, Heidelberg, Leipzig, Loewenstein, Mainz, Marburg, München, Wuppertal
Age
40 years to 75 years
People
1,196 worldwide
Run by
GlaxoSmithKline
See details and how to joinNCT07177339 · EU 2025-521108-23-00
Phase 4Taking people
Molecular Signatures Associated With Response to ICS Treatment in Patients With COPD Stratified by Eosinophil Levels
Where
Marburg
Age
40 years and over
People
135 worldwide
Run by
Maria Joyera Rodríguez
See details and how to joinNCT06334575
No phaseTaking people
The CATALINA Study
Where
Großhansdorf, Itzehoe, Kiel, Marburg
Age
18 years and over
People
1,000 worldwide
Run by
Wim Janssens
See details and how to joinNCT05008081
No phaseNot yet taking people in Germany
Investigation of the Effects of Oxidized Antigens on the T-Cell Response and the Epigenetic Reprogramming of Neutrophils in Lung Diseases - OXIGENE -
Where
Borstel, Kiel
Age
18 years and over
People
100
Run by
Research Center Borstel
See details and how to joinNCT07386912
No phaseTaking people
Sympathetic Nerve Activity Predictors in Patients With Chronic Obstructive Pulmonary Disease
Where
Aachen
Age
18 years and over
People
135
Run by
RWTH Aachen University
See details and how to joinNCT04849806
No phaseTaking people
Diaphragmatic Function as a Biomarker
Where
Aachen
Age
18 years and over
People
800
Run by
RWTH Aachen University
See details and how to joinNCT05903001