COPD trials in Italy

In Italy 37 Also abroad 557

37 trials · From ClinicalTrials.gov and EU CTIS (euclinicaltrials.eu), checked 10 November 2026. Ask the study team whether a trial fits you.

No phaseTaking people
Study on Impact of Maximal Strength Training in Patients With COPD
Where
Lumezzane
Age
50 years to 80 years
People
20
Run by
Istituti Clinici Scientifici Maugeri SpA
See details and how to joinNCT03799354
Phase 2Not yet taking people in Italy
The MAB Trial: A Study of Tozorakimab to Reduce Lung Inflammation and Promote Lung Healing in People with COPD.
Where
Milan
Age
18 years and over
People
60 worldwide
Run by
University Of Leicester
See details and how to join2025-522359-24-00 · EU 2025-522359-24-00
Phase 2Taking people
A Study to Investigate the Effect of AZD6793 in Participants With Moderate to Very Severe Chronic Obstructive Pulmonary Disease
Where
Busto Arsizio, Cuneo, Ferrara, Milan, Monza, Naples, Pavia, Roma, Statte, Telese Terme
Age
40 years and over
People
987 worldwide
Run by
AstraZeneca
See details and how to joinNCT07082738
Phase 2/3Taking people
A Study to Learn About the Study Medicine Called PF-07275315 in People With Moderate to Severe Chronic Obstructive Pulmonary Disease
Where
Bergamo, Catania, Ferrara, Milan, Naples, Reggio Emilia, Rome
Age
35 years to 80 years
People
1,156 worldwide
Run by
Pfizer
See details and how to joinNCT07363694 · EU 2024-518587-12-00
Phase 4Taking people
A Study to Investigate Airway Inflammation With Dupilumab Subcutaneously in Participants Aged ≥40 to ≤85 Years With Chronic Obstructive Pulmonary Disease.
Where
Cona, Giugliano in Campania, Orbassano, Siena
Age
40 years to 85 years
People
218 worldwide
Run by
Sanofi
See details and how to joinNCT07053423
Phase 3Taking people
Efficacy, Safety, and Tolerability Study of Lunsekimig Compared With Placebo in Adult Participants With Inadequately Controlled Chronic Obstructive Pulmonary Disease (COPD) Characterized by an Eosinophilic Phenotype
Where
Cona, Milan, Padova, Pavia, Reggio Emilia, Rozzano, Telese Terme, Tradate (Va)
Age
40 years to 80 years
People
942 worldwide
Run by
Sanofi
See details and how to joinNCT07190209 · EU 2024-518016-39-00
Phase 4Taking people
This After Market Study is Seeing if Dupilumab Plus Usual Standard of Care (SOC) is Better Than Usual Care Alone for Adult Participants After a Severe Chronic Obstructive Pulmonary Disease (COPD) Flare-Up Requiring Hospitalization
Where
Ferrara, Genoa, Rozzano
Age
40 years and over
People
754 worldwide
Run by
Regeneron Pharmaceuticals
See details and how to joinNCT07587658 · EU 2025-524392-23-00
Phase 2Not yet taking people in Italy
A Randomized, Double-Blind, Placebo-controlled, Parallel Arm, 52-week Study to Assess Efficacy, Safety, Tolerability, and Pharmacokinetics of Two Doses of EXPD-101 in Participants with COPD
Where
Bologna, Ferrara, Milan, Pisa
Age
18 years and over
People
183 worldwide
Run by
Expedition Therapeutics Inc.
See details and how to join2026-525216-34-00 · EU 2026-525216-34-00
Phase 3Taking people
Depemokimab as an Extended Treatment Duration Biologic in Adults With Chronic Obstructive Pulmonary Disease (COPD) and Type 2 Inflammation (ENDURA-2)
Where
Bari, Catania, Ferrara, Foggia, Genoa, Rome, Rozzano, Telese Terme
Age
40 years to 80 years
People
961 worldwide
Run by
GlaxoSmithKline
See details and how to joinNCT06961214 · EU 2024-520417-41-00
Phase 3Taking people
A Study Evaluating the Efficacy of Budesonide, Glycopyrronium and Formoterol Fumarate Metered Dosed Inhaler on Cardiopulmonary Outcomes in Chronic Obstructive Pulmonary Disease
Where
Ancona, Florence, Genoa, Mestre (VE), Milan, Modena, Naples, Pavia, Perugia, Rome, Siena, Varese
Age
40 years to 80 years
People
5,250 worldwide
Run by
AstraZeneca
See details and how to joinNCT06283966 · EU 2023-507407-59-00
No phaseTaking people
An Evaluation of the AeriSeal System for CONVERTing Collateral Ventilation Status in Patients With Severe Emphysema
Where
Brescia
Age
40 years to 80 years
People
200 worldwide
Run by
Pulmonx Corporation
See details and how to joinNCT06035120
Phase 3Taking people
A Study to Investigate the Efficacy and Safety of Tezepelumab in Adult Participants With Moderate to Very Severe COPD (D5241C00006)
Where
Ferrara, Florence, Montebelluna, Naples, Pavia, Rome, Sassari, Telese Terme, Tradate
Age
40 years to 80 years
People
990 worldwide
Run by
AstraZeneca
See details and how to joinNCT06883305 · EU 2024-517458-90-00
Phase 2Taking people
A study to investigate the effect of AZD6793 in participants with moderate to very severe chronic obstructive pulmonary disease
Where
Busto Arsizio, Cuneo, Ferrara, Monza, Naples, Pavia, Rome, Statte, Telese Terme
Age
18 years and over
People
307 worldwide
Run by
AstraZeneca AB
See details and how to join2025-520473-40-00 · EU 2025-520473-40-00
Phase 3Taking people
eValuating the Efficacy and Safety of InitiatinG depemokImab earLy therApy iN Chronic Obstructive Pulmonary Disorder (COPD) With Type 2 Inflammation
Where
Brescia, Ferrara, Naples, Rome, Taranto
Age
40 years to 75 years
People
1,196 worldwide
Run by
GlaxoSmithKline
See details and how to joinNCT07177339 · EU 2025-521108-23-00
No phaseTaking people
Identification of Diagnostic and Prognostic Biomarkers in the Pathological Continuum of Bronco Chronic Obstructive Pulmonary Disease, Idiopathic Pulmonary Fibrosis and Pulmonary Neoplasia
Where
Milan
Age
18 years and over
People
120
Run by
Fondazione Don Carlo Gnocchi ETS
See details and how to joinNCT07707245
No phaseTaking people
Effect of Combined Endurance Training on ADL and Walking in COPD Patients
Where
Lumezzane, Montescano, Tradate
People
36
Run by
Istituti Clinici Scientifici Maugeri SpA
See details and how to joinNCT05708443
No phaseTaking people
Effect of Simeox® on Residual Volume in COPD Patients With Pulmonary Hyperinflation
Where
Codogno
Age
18 years and over
People
23
Run by
Azienda Socio Sanitaria Territoriale di Lodi
See details and how to joinNCT07665931
No phaseTaking people
Effects of Oxygen Supplementation During the 6-Minute Walk Test in Chronic Respiratory Failure or Exertional Hypoxemia
Where
Bari, Lumezzane, Montescano, Pavia, Taranto, Veruno
Age
18 years and over
People
114
Run by
Istituti Clinici Scientifici Maugeri SpA
See details and how to joinNCT07451977
No phaseTaking people
The CATALINA Study
Where
Ferrara
Age
18 years and over
People
1,000 worldwide
Run by
Wim Janssens
See details and how to joinNCT05008081
No phaseTaking people
Clinical-ultrasonographic Assessment of Pulmonary Emphysema
Where
Acquaviva Delle Fonti, Naples, Rome, Trento
Age
18 years and over
People
1,628
Run by
Fondazione Policlinico Universitario Agostino Gemelli IRCCS
See details and how to joinNCT06533371
No phaseTaking people
Ultrasound and Respiratory Physiological Signals in Lung Diseases
Where
Rome
Age
18 years and over
People
25
Run by
Fondazione Policlinico Universitario Agostino Gemelli IRCCS
See details and how to joinNCT06068647
No phaseNot yet taking people in Italy
Effect on Bronchodilation Response and Ventilation Heterogeneity of Different Inhalation Volumes in COPD
Where
Milan
Age
40 years and over
People
30
Run by
University of Milan
See details and how to joinNCT05381415
No phaseEnrolling by invitation
The Italian Registry of Patients With Chronic Obstructive Pulmonary Disease
Where
Milan
Age
40 years and over
People
10,000
Run by
University of Milan
See details and how to joinNCT06652776
Phase 4Not yet taking people in Italy
Effect of add-on Doxofylline on Lung Function in Stable COPD
Where
Milan
Age
40 years and over
People
78
Run by
University of Milan
See details and how to joinNCT04238221
Phase 4Not yet taking people in Italy
Immuno-inflammatory Response of Erdosteine in COPD
Where
Milan
Age
45 years and over
People
30
Run by
Pierachille Santus, MD, PhD
See details and how to joinNCT07329946 · EU 2025-524821-42-00