Coronary artery disease trials in United States

In United States 181 Also abroad 1313

181 trials · From ClinicalTrials.gov, checked 12 November 2026. Ask the study team whether a trial fits you.

No phaseEnrolling by invitation
Blood Collection for Research Related to Certain Diseases Involving Blood Vessels
Where
Bethesda, Fairfax
Age
18 years to 100 years
People
2,000
Run by
National Heart, Lung, and Blood Institute (NHLBI)
See details and how to joinNCT00047996
Phase 3Not yet taking people in United States
Cilostazol for Prevention of Recurrent Stroke Trial
Where
Akron, Ann Arbor, Atlanta, Baltimore, Birmingham, Boston, Brooklyn, Carbondale, Chandler, Charleston, Charlottesville, Cincinnati, Columbia, Durham, Erie, Flint, Fontana, Grand Junction, Iowa City, Jacksonville, Kansas City, La Jolla, Los Angeles, Madison, Memphis, Minneapolis, Mobile, Morgantown, Murray, New Haven, New York, Oklahoma City, Philadelphia, Pomona, Portland, Richmond, Saint Paul, Salt Lake City, San Antonio, Seattle, Stanford, St Louis, Wilmington, Winston-Salem
Age
40 years and over
People
2,000
Run by
Stanford University
See details and how to joinNCT07174414
No phaseTaking people
Safety and Effectiveness of the Sphere-9™ Catheter and Affera™ Ablation System for the Treatment of Ventricular Tachycardia (Sphere VT)
Where
Austin, Columbus, Indianapolis, Littleton, Manhasset, New York, Winston-Salem
Age
18 years to 85 years
People
260
Run by
Medtronic Cardiac Ablation Solutions
See details and how to joinNCT07585968
No phaseTaking people
Virtue® SAB in the Treatment of Coronary ISR Trial
Where
Asheville, Atlanta, Baltimore, Cincinnati, Gainesville, Greenville, Hollywood, Indianapolis, Kyle, Milwaukee, Nashville, New York, Pensacola, Philadelphia, Phoenix, Roslyn, Royal Oak, Springfield, Tupelo, Wichita, York
Age
18 years and over
People
740
Run by
Orchestra BioMed, Inc
See details and how to joinNCT07045194
No phaseNot yet taking people in United States
Rapid Inflation/Deflation Compared With Prolonged High-Pressure Balloon Inflation
Where
Little Rock
Age
19 years and over
People
40
Run by
Central Arkansas Veterans Healthcare System
See details and how to joinNCT01952873
No phaseTaking people
Prevail Global Study
Where
Allentown, Anderson, Ann Arbor, Atlanta, Birmingham, Buffalo, Camden, Charleston, Chicago, Cincinnati, Clearwater, Cleveland, Columbus, Dallas, Edgewood, Edina, Fort Wayne, Gainesville, Grand Rapids, Greensboro, Harrisburg, Houston, Huntsville, Kansas City, La Crosse, Little Rock, Louisville, Loveland, Manhasset, Miami, Minneapolis, Missoula, Naperville, Nashville, New York, Overland Park, Paramus, Philadelphia, Plano, Portland, Providence, Roslyn, Saint Cloud, Seattle, Stanford, Tucson, Washington D.C., Wichita, Wilmington, Ypsilanti
Age
18 years and over
People
1,205 worldwide
Run by
Medtronic Vascular
See details and how to joinNCT06535854
No phaseTaking people
Product Surveillance Registry
Where
Albany, Albuquerque, Aliso Viejo, Allentown, Ann Arbor, Aurora, Austin, Bay City, Bay Shore, Bethlehem, Birmingham, Boston, Bradenton, Bremerton, Burlington, Camden, Chandler, Chapel Hill, Charleston, Charlottesville, Chicago, Chula Vista, Clearwater, Cleveland, Colorado Springs, Colton, Columbia, Columbus, Coon Rapids, Dallas, Danville, Darien, Davie, Dayton, Durham, Edenton, Edgewood, Erie, Evansville, Fairfax, Falls Church, Fort Worth, Fredericksburg, Gainesville, Germantown, Grapevine, Hartford, Holyoke, Houston, Huntington, Huntsville, Hyattsville, Indianapolis, Iowa City, Jackson, Jacksonville, Kansas City, Kyle, La Jolla, Lakewood, Lancaster, Lansing, Lebanon, Little Rock, Los Angeles, Louisville, Madison, Manhasset, Marlton, Mechanicsburg, Memphis, Minneapolis, Morgantown, Morristown, Mount Kisco, Mount Orab, Napa, Naples, Nashville, New Haven, New Hyde Park, New Orleans, New York, Ocean Township, Omaha, Orangeburg, Panama City, Philadelphia, Phoenix, Pinehurst, Pittsburgh, Plano, Port Jefferson, Portland, Poughkeepsie, Raleigh, Redwood City, Reno, Riverhead, Robbinsdale, Rochester, Rochester Hills, Roslyn, Safety Harbor, Saint Cloud, Salinas, Salisbury, Salt Lake City, San Antonio, San Diego, Sarasota, Seattle, Sewickley, Silver Spring, Sioux Falls, Spartanburg, Spokane, Stanford, Staten Island, St Louis, Stony Brook, Tampa, Teaneck, Temecula, Torrance, Tyler, Utica, Ventura, Washington D.C., West Des Moines, Weston, Wilkes-Barre, Ypsilanti
People
100,000 worldwide
Run by
Medtronic
See details and how to joinNCT01524276
No phaseTaking people
AGENT DCB STANCE: Safety and Effectiveness Study of AGENT Drug-Coated Balloon Compared to Standard of Care Percutaneous Coronary Intervention (PCI) Treatment for de Novo Coronary Lesions
Where
Ann Arbor, Atlanta, Austin, Bellevue, Boston, Brooklyn, Charleston, Charlotte, Charlottesville, Cincinnati, Cleveland, Columbia, Columbus, Coon Rapids, Dallas, Detroit, Evanston, Falls Church, Gainesville, Glenview, Grand Rapids, Houston, Humble, Jonesboro, Kansas City, La Jolla, Littleton, Los Angeles, Marietta, Mechanicsburg, Miami Beach, New York, Plano, Portland, Providence, Roslyn, San Antonio, San Francisco, Scottsdale, Stanford, The Bronx, Thousand Oaks, York
Age
18 years and over
People
1,616 worldwide
Run by
Boston Scientific Corporation
See details and how to joinNCT06959524
No phaseTaking people
The Canadian CABG or PCI in Patients With Ischemic Cardiomyopathy Trial (STICH3C)
Where
Baltimore, Cleveland, Los Angeles, Louisville, New Haven, Rochester
Age
18 years and over
People
754 worldwide
Run by
Sunnybrook Health Sciences Centre
See details and how to joinNCT05427370
No phaseNot yet taking people in United States
ProActive Athlete Heart Program: Proposal for Cardiac Risk Screening in Former High-Intensity Athletes
Where
Plano
Age
30 years and over
People
100
Run by
Baylor Research Institute
See details and how to joinNCT07460583
Phase 2Taking people
Dose-finding Study of YMI024 to Assess Efficacy, Safety, and Tolerability in Adults With Stable Coronary Artery Disease and Elevated hsCRP
Where
Amarillo, Coral Gables, Fairhope, Foley, Ft. Washington, Los Angeles, Oxon Hill, Wichita, Winchester
Age
18 years to 80 years
People
180 worldwide
Run by
Novartis Pharmaceuticals
See details and how to joinNCT07830719 · EU 2026-525974-21-00
Phase 2Taking people
Prevent Cardiac Surgery Associated AKI Trial
Where
Washington D.C.
Age
18 years to 70 years
People
242
Run by
George Washington University
See details and how to joinNCT06620523
No phaseTaking people
Abbott Vascular Medical Device Registry
Where
Birmingham, Chicago, Columbus, Kingsport, Lincoln, Little Rock, Los Angeles
Age
18 years and over
People
3,784 worldwide
Run by
Abbott Medical Devices
See details and how to joinNCT04573660
No phaseTaking people
Evaluating New Radiation Techniques for Cardiovascular Imaging
Where
Bethesda
Age
18 years to 100 years
People
5,000
Run by
National Heart, Lung, and Blood Institute (NHLBI)
See details and how to joinNCT01621594
Phase 4Taking people
Dual Antiplatelet Therapy Escalation From Standard-dose Clopidogrel to Low-Dose Prasugrel in Patients With High Bleeding and Ischemic Risk Undergoing PCI: A Prospective, Randomized Pharmacodynamic Study (TAILOR-BLEED-2)
Where
Jacksonville
Age
18 years and over
People
40
Run by
University of Florida
See details and how to joinNCT07025148
No phaseTaking people
Technical and Translational Development of Cardiovascular Magnetic Resonance (CMR) Imaging
Where
Bethesda
Age
7 years to 100 years
People
5,000
Run by
National Heart, Lung, and Blood Institute (NHLBI)
See details and how to joinNCT03581318
Phase 3Taking people
Low Dose ColchicinE in pAtients With Peripheral Artery DiseasE to Address Residual Vascular Risk
Where
Ann Arbor, Boston, Chapel Hill, Chicago, Columbus, Dallas, Detroit, Durham, El Paso, Gainesville, Greensboro, McKinney, Milwaukee, Nashville, Newark, New Haven, New York, Norfolk, Raleigh, Rochester, Seattle, Tampa
Age
18 years and over
People
6,150 worldwide
Run by
Population Health Research Institute
See details and how to joinNCT04774159
No phaseTaking people
ASCVD Management Using CCTA in Prostate Cancer Patients on ADT
Where
Carmel, Indianapolis
Age
40 years and over
People
100
Run by
Indiana University
See details and how to joinNCT05879913
No phaseTaking people
ANDREAS Registry (Assessment of Novel Drug-coated Balloon Revascularization: Effectiveness, Angiographic Outcomes, and Safety)
Where
Atlanta, Boston, Charlotte, Cleveland, Durham, Fort Lauderdale, Johns Creek, Minneapolis, Nashville, New York, Phoenix, Roslyn
Age
18 years and over
People
5,000 worldwide
Run by
Emory University
See details and how to joinNCT07559903
No phaseNot yet taking people in United States
REFINE-CAC Protocol: Risk Evaluation With AI-CPA + HCS For Patients IN Whom Calcium is confirmEd to Improve Coronary Artery Disease Care
Where
New York
Age
40 years to 79 years
People
500
Run by
HeartFlow, Inc.
See details and how to joinNCT07853716
No phaseTaking people
Assessment of Coronary Microvascular Dysfunction After STEMI Using Continuous Saline Thermodilution
Where
Cleveland
Age
18 years and over
People
35
Run by
The Cleveland Clinic
See details and how to joinNCT06795035
No phaseTaking people
Efficacy of the COronary SInus Reducer in Patients With Refractory Angina II
Where
Ann Arbor, Atlanta, Austin, Boston, Carmel, Charlotte, Charlottesville, Chicago, Cincinnati, Cleveland, Columbus, Detroit, Fort Worth, Gainesville, Gainsville, Grand Rapids, Hackensack, Houma, Houston, Jackson, Jacksonville, Kansas City, Littleton, Long Beach, Los Angeles, Louisville, Madison, Marietta, Miami Beach, Milwaukee, Minneapolis, Munster, Naples, Nashville, New Haven, New York, Norfolk, Pensacola, Phoenix, Pittsburgh, Plano, Portland, Rochester, Roslyn, San Antonio, San Diego, San Francisco, Scottsdale, Southfield, Springfield, Tallahassee, Tampa, Thousand Oaks, Tucson, Tulsa, Tupelo, Washington D.C., Wichita
Age
18 years and over
People
380 worldwide
Run by
Shockwave Medical, Inc.
See details and how to joinNCT05102019
No phaseTaking people
CARE-CP (Testing a Cardiovascular Ambulatory Rapid Evaluation for Patients With Chest Pain)
Where
Charlotte, Detroit, Winston-Salem
Age
21 years and over
People
502
Run by
Wake Forest University Health Sciences
See details and how to joinNCT05897632
No phaseNot yet taking people in United States
Clinical Evidence With Biomarker Confirmation for PPMI in PCI Clinical Trials Study
Where
Boston
Age
18 years and over
People
1,000
Run by
Baim Institute for Clinical Research
See details and how to joinNCT07848529
No phaseTaking people
A Randomized Comparison of Stage-Based Care Versus Risk Factor-Based Care for Prevention of Cardiovascular Events
Where
Abilene, Akron, Augusta, Aurora, Beaumont, Beverly Hills, Boca Raton, Boston, Bowie, Brooklyn, Camp Hill, Canoga Park, Chandler, Chapel Hill, Charleston, Chicago, Chula Vista, Cleveland, Columbia, Cross City, Denver, Detroit, Dunwoody, Durham, Edgewood, Everett, Fargo, Fayetteville, Flemington, Glenview, Granada Hills, Greenville, Hialeah, Houston, Huntington Park, Indianapolis, Indian Wells, Jackson Heights, Jacksonville, Kalispell, Knoxville, La Jolla, Lake Success, Lancaster, Laredo, Las Vegas, Lewisville, Lincoln, Lithia Springs, Loma Linda, Long Beach, Louisville, Macon, Marlton, McKinney, Meridian, Mesquite, Miami, Miami Beach, Minneapolis, Missoula, Monterey Park, Morehead City, Mount Kisco, Nashville, New Brunswick, Newhall, New Orleans, New York, Norcross, Northridge, Oklahoma City, Orange, Palo Alto, Paramus, Pensacola, Pompano Beach, Powder Springs, Richmond, Riverdale, San Fernando, San Marcos, Savannah, Scottsdale, Seattle, Stephenville, St Louis, Sun City, Tampa, Tarzana, Teaneck, Thomasville, Torrance, Tucson, Tulsa, Valencia, Valley Village, West Des Moines, West Valley City, Winston-Salem, Ypsilanti
Age
55 years and over
People
7,500
Run by
Cleerly, Inc.
See details and how to joinNCT06112418