Crohn's disease trials in United States

In United States 125 Also abroad 422

125 trials · From ClinicalTrials.gov, checked 11 November 2026. Ask the study team whether a trial fits you.

No phaseTaking people
A Randomized Crossover Trial of Bright Light Therapy in Crohn's Disease on Intestinal Barrier Homeostasis
Where
Charleston, Chicago
Age
18 years and over
People
30
Run by
Rush University Medical Center
See details and how to joinNCT05579392
Phase 4Taking people
A Study of Vedolizumab in Adults With Ulcerative Colitis (UC) or Crohn's Disease (CD) in the Community Setting
Where
Albuquerque, Atlanta, Baton Rouge, Bellevue, Birmingham, Bridgeton, Brooksville, Carmel, Cedarhurst, Chandler, Charlotte, Chevy Chase, Cincinnati, Clearwater, Colorado Springs, Columbia, Crestview Hills, Dayton, Decatur, Downers Grove, Elmhurst, El Paso, Escondido, Framingham, Fresh Meadows, Georgetown, Gilbert, Glen Burnie, Glenview, Greenville, Hialeah, Houston, Hutchinson, Kansas City, Katy, Kingsport, Kingwood, Kissimmee, Lafayette, Lake Barrington, Lake Success, Liberty Township, Little Rock, Littleton, Lubbock, Mentor, Metairie, Miami, Mobile, Murrieta, Naperville, New Bedford, Newport Beach, New York, Oak Lawn, Ogden, Orange, Orlando, Pensacola, Pinehurst, Pinellas Park, Plymouth, Portland, Providence, Reno, Roanoke, Rochester, Rockford, San Diego, Seaford, Sioux Falls, Southaven, Springboro, Springfield, Statesville, Suffolk, Summerville, Sun City, Syracuse, Tomball, Utica, Waco, Webster, Weldon Spring, Westfield, Westlake, West Nyack, Williamsburg, Wilmington, Wyoming, Ypsilanti
Age
18 years to 80 years
People
200
Run by
Takeda
See details and how to joinNCT06581328
Phase 2Taking people
Study of Advanced Therapies for the Treatment of Adult Participants With Moderately to Severely Active Crohn's Disease or Ulcerative Colitis
Where
Anaheim, Asheville, Beavercreek, Bellaire, Bellevue, Boise, Bradenton, Colorado Springs, Coronado, Des Plaines, Dothan, Flowood, Fort Worth, Garland, Georgetown, Glenview, Greenville, Gurnee, Houston, Kissimmee, Knoxville, Lancaster, Lansdowne Town Center, Largo, Las Vegas, Los Alamitos, Louisville, Lubbock, Macon, Mandeville, Mansfield, Memphis, Metairie, Miami, Milwaukee, New Albany, New Bedford, New Port Richey, New York, Oak Lawn, Orlando, Oxford, Phoenix, Providence, Rialto, Richmond, Roswell, San Antonio, Shenandoah, Shreveport, Southlake, St Louis, Sun City, Tacoma, Tampa, Tyler, Vancouver, Webster, Westlake, Wyoming
Age
18 years to 75 years
People
2,000 worldwide
Run by
AbbVie
See details and how to joinNCT07697456 · EU 2026-525959-86-00
No phaseTaking people
Immune Regulation in Ulcerative Colitis or Crohn s Disease
Where
Bethesda
Age
1 day to 75 years
People
1,000
Run by
National Institute of Allergy and Infectious Diseases (NIAID)
See details and how to joinNCT00001184
Phase 3Taking people
A Study to Assess the Efficacy and Safety of Induction Therapy With Afimkibart (RO7790121) in Participants With Moderately to Severely Active Crohn's Disease
Where
Atlanta, Baltimore, Baton Rouge, Beavercreek, Brooklyn, Charlotte, Chevy Chase, Chicago, Cleveland, Colorado Springs, Columbia, Cordova, Dallas, Doral, Dothan, Flowood, Fort Worth, Fresh Meadows, Garland, Glendale, High Point, Houston, Huntington, Kansas City, Lakeland, Lake Success, Lancaster, Lebanon, Lehigh Acres, Louisville, Lubbock, Miami, Miami Beach, Miramar, Moorestown, Nashville, New Brunswick, Newport Beach, North Worcester, Orlando, Philadelphia, Pomona, Port Orange, Providence, Redwood City, Richmond, San Antonio, San Diego, Santa Clarita, Seattle, Shreveport, St Louis, Tacoma, Tampa, The Bronx, Tyler, Utica, Webster, Weston, Wyoming
Age
16 years to 80 years
People
425 worldwide
Run by
Hoffmann-La Roche
See details and how to joinNCT06819891 · EU 2024-513054-30-00
Phase 4Taking people
Open-label Single-arm Study to Assess the Efficacy of Mirikizumab in Patients With Inflammatory Strictures Due to CD
Where
Chicago, Miami, Orlando, Salt Lake City
Age
18 years and over
People
60 worldwide
Run by
Alimentiv Inc.
See details and how to joinNCT06997965
No phaseNot yet taking people in United States
Online Pain Education for Crohn's Disease and Ulcerative Colitis
Where
Los Angeles
Age
18 years and over
People
60
Run by
Cedars-Sinai Medical Center
See details and how to joinNCT07671313
Phase 3Taking people
An Induction Study to Investigate the Efficacy and Safety of Duvakitug in Participants With Moderately to Severely Active Crohn's Disease
Where
Atlanta, Aurora, Baltimore, Baton Rouge, Baytown, Bellevue, Boston, Canoga Park, Canton, Chapel Hill, Charlotte, Chicago, Clermont, Cleveland, Clive, Colorado Springs, Columbia, Columbus, Cordova, Coronado, Dallas, Dayton, Denver, Des Plaines, Durham, East Orange, Escondido, Fargo, Fayetteville, Folsom, Freehold, Gainesville, Glenview, Gurnee, Harlingen, Hershey, Houma, Idaho Falls, Jackson, Kansas City, Kingsport, Kingwood, Kissimmee, Lake Jackson, Lancaster, Las Vegas, Laurel, Lexington, Liberty, Little Rock, Los Angeles, Lubbock, Lynchburg, Mandeville, Marrero, Maspeth, Mesquite, Metairie, Miami, Milwaukee, Monroe, Morristown, Murrieta, New Albany, New Haven, New Iberia, New York, Norman, Novi, Orlando, Oxnard, Palmetto Bay, Peoria, Philadelphia, Pittsburgh, Portland, Providence, Raleigh, Rancho Cucamonga, Richmond, Sacramento, San Antonio, San Diego, Sandy Springs, Scottsdale, Snellville, Somers Point, Southlake, Sparta, Springboro, St Louis, Sunrise, Suwanee, Tampa, Tarzana, The Bronx, Thousand Oaks, Toledo, Tomball, Tucson, Tyler, Valencia, Vancouver, Victorville, Waterloo, West Jordan, Westlake, Worcester, Wyoming
Age
16 years to 80 years
People
980 worldwide
Run by
Sanofi
See details and how to joinNCT07184931
Phase 3Taking people
A Maintenance Study to Investigate the Efficacy and Safety of Duvakitug in Participants With Moderately to Severely Active Crohn's Disease
Where
Baton Rouge, Chapel Hill, Colorado Springs, Columbus, Fayetteville, Gurnee, Kissimmee, Liberty, Lubbock, Mandeville, Maspeth, Mesquite, Metairie, Miami, Monroe, New Albany, New York, Orlando, Philadelphia, Pittsburgh, Providence, San Antonio, Southlake, St Louis, Tampa, Tyler, Vancouver, Westlake, Wyoming
Age
16 years to 80 years
People
751 worldwide
Run by
Sanofi
See details and how to joinNCT07184944
Phase 1Taking people
Safety of Cultured Allogeneic Adult Umbilical Cord or Placental Derived Mesenchymal Stem Cell Intravenous Infusion for Crohn's Disease or Ulcerative Colitis
Where
Naples
People
15 worldwide
Run by
The Foundation for Orthopaedics and Regenerative Medicine
See details and how to joinNCT05003947
Phase 3Taking people
A Study to Assess Adverse Events, Change in Disease Activity, and How Intravenous and Subcutaneous Risankizumab Moves Through the Body of Pediatric Participants With Moderately to Severely Active Crohn's Disease
Where
Aurora, Cleveland, Indianapolis, Little Rock, Minneapolis, Morristown, New York, Oakland, Orlando, Phoenix, Waltham
Age
2 years to 17 years
People
110 worldwide
Run by
AbbVie
See details and how to joinNCT05995353 · EU 2022-502050-14-00
Phase 3Taking people
A Study to Assess the Efficacy and Safety of Induction and Maintenance Therapy With Afimkibart (RO7790121) in Participants With Moderately to Severely Active Crohn's Disease
Where
Arlington, Atlanta, Beavercreek, Boston, Brooksville, Brunswick, Charleston, Charlotte, Chesapeake, Chicago, Cincinnati, Clearwater, Cleveland, Columbus, Coral Gables, Crestview Hills, Dothan, El Paso, Farmington Hills, Fuquay-Varina, Garden Grove, Georgetown, Germantown, Glenview, Greenville, Gurnee, Harlingen, Hershey, Hialeah, Houston, Idaho Falls, Indianapolis, Inglewood, Kissimmee, La Jolla, Lakewood Rch, Lancaster, Lansdowne Town Center, Liberty Township, Littleton, Lone Tree, Los Alamitos, Louisville, Lynchburg, Macon, Mansfield, Mesquite, Miami, Monroe, Nashville, New Albany, New York, Norman, North Las Vegas, North Massapequa, Orlando, Oxford, Phoenix, Providence, Queens Village, Richmond Hill, Roanoke, Rochester, San Antonio, San Diego, San Francisco, Seattle, Southaven, Southlake, Sun City, Tampa, Temple, Temple Terrace, Tucson, Tyler, Uniontown, Vancouver, Westlake, Weston, Wichita, Williamsburg, Zephyrhills
Age
16 years to 80 years
People
600 worldwide
Run by
Hoffmann-La Roche
See details and how to joinNCT06819878 · EU 2024-513053-69-00
Phase 3Taking people
A Long-Term Extension Study of Vedolizumab in Children and Teenagers With Ulcerative Colitis (UC) or Crohn's Disease (CD)
Where
Charleston, Cleveland, Detroit, Hershey, Loma Linda, Morristown, New York, Oklahoma City, Orange, Park Ridge, Phoenix, Tacoma
Age
2 years to 17 years
People
70 worldwide
Run by
Takeda
See details and how to joinNCT06405087 · EU 2023-508804-39-00
No phaseTaking people
Study of Efficacy and Adherence to Subcutaneous vs. Intravenous Vedolizumab in Patients With Inflammatory Bowel Disease Using a Novel Remote MONITORing Intervention
Where
Chapel Hill, Chevy Chase, Cincinnati, Nashville, New Orleans, New York
Age
18 years and over
People
200
Run by
Mercy Medical Center
See details and how to joinNCT06750731
Phase 3Taking people
A Master Protocol (AMAZ): A Study of Mirikizumab (LY3074828) in Pediatric Participants With Ulcerative Colitis or Crohn's Disease (SHINE-ON)
Where
Atlanta, Boston, Fairfax, Fort Worth, Hartford, New York, Philadelphia, San Francisco, St Louis, Waltham
Age
2 years to 19 years
People
150 worldwide
Run by
Eli Lilly and Company
See details and how to joinNCT04844606
Phase 3Taking people
A Study of Mirikizumab (LY3074828) in Pediatric Participants With Crohn's Disease
Where
Atlanta, Boston, Burlington, Dayton, Fort Worth, Hartford, Indianapolis, Los Angeles, Morristown, New York, Philadelphia, Seattle
Age
2 years to 17 years
People
90 worldwide
Run by
Eli Lilly and Company
See details and how to joinNCT05509777 · EU 2024-511472-32-00
No phaseTaking people
Family Members at INcreased-risk for Developing Inflammatory Bowel Disease
Where
Boston
Age
14 years and over
People
50
Run by
Massachusetts General Hospital
See details and how to joinNCT06655415
Phase 1Taking people
Testing an Immunotherapy Anti-cancer Drug, Nivolumab, for Advanced Cancers in Patients With Autoimmune Disorders, AIM-NIVO
Where
Atlanta, Baltimore, Bethesda, Birmingham, Boston, Chicago, City of Saint Peters, Columbus, Creve Coeur, Dallas, Detroit, Fairway, Fort Worth, Hays, Houston, Kansas City, Lawrence, Lee's Summit, Lexington, Mineola, New Brunswick, New Haven, New York, North Kansas City, Olathe, Overland Park, Palo Alto, Philadelphia, Pittsburg, Pittsburgh, Richardson, Richmond, Sacramento, Salina, Salt Lake City, St Louis, Topeka, Washington D.C., Westwood
Age
18 years and over
People
300 worldwide
Run by
National Cancer Institute (NCI)
See details and how to joinNCT03816345
No phaseTaking people
Ketogenic and Carnivore (Lion) Diets for Inflammatory Bowel Disease and Rheumatoid Arthritis
Where
Charlottesville
Age
18 years to 64 years
People
160
Run by
Fuller Research Foundation
See details and how to joinNCT07524244
No phaseTaking people
Feasibility of a Wireless Thermal Capsule Endoscopy to Detect Gastrointestinal Thermal Variance
Where
Boston
Age
18 years to 75 years
People
25
Run by
Massachusetts General Hospital
See details and how to joinNCT07033208
No phaseNot yet taking people in United States
The EDICT Trial - Therapy for Inflammatory Bowel Disease Flares
Where
Winston-Salem
Age
21 years and over
People
42
Run by
Wake Forest University Health Sciences
See details and how to joinNCT07143188
Phase 2Taking people
Study of Targeted Therapies for the Treatment of Adult Participants With Moderate to Severe Crohn's Disease
Where
Asheville, Boise, Cedar Park, Chevy Chase, Chicago, Cincinnati, Clermont, Colorado Springs, Columbia, Columbus, Coronado, Danbury, Dothan, El Paso, Gainesville, Garland, Hershey, Houston, Indianapolis, Inverness, Johnson City, La Jolla, Lake Success, Las Vegas, Lexington, Liberty, Lubbock, Macon, Mansfield, Margate, Miami, Mobile, New Bedford, New Haven, New Port Richey, New York, Novi, Ogden, Oklahoma City, Orangeburg, Orange City, Orlando, Peoria, Philadelphia, Rochester, Rockville, Sacramento, Salt Lake City, San Antonio, San Diego, Seattle, Southlake, Springfield, St Louis, Tacoma, Tampa, Tyler, Yonkers, Zephyrhills
Age
18 years to 75 years
People
590 worldwide
Run by
AbbVie
See details and how to joinNCT06548542 · EU 2024-513009-30-00
No phaseTaking people
Non-nutritive Sweeteners in Inflammatory Bowel Disease
Where
Chagrin Falls, Cleveland, Westlake
Age
18 years to 70 years
People
40
Run by
University Hospitals Cleveland Medical Center
See details and how to joinNCT07769437
No phaseTaking people
Tailored Anti-Inflammatory American Diet for Patients With Crohn's Disease
Where
Miami
Age
16 years to 75 years
People
122
Run by
University of Miami
See details and how to joinNCT07671872
No phaseNot yet taking people in United States
Digital Mind Body Intervention Among Black and Hispanic Patients Living With Inflammatory Bowel Disease
Where
The Bronx
Age
18 years and over
People
40
Run by
Montefiore Medical Center
See details and how to joinNCT06510296