Cystic fibrosis trials in France

In France 28 Also abroad 188

28 trials · From ClinicalTrials.gov and EU CTIS (euclinicaltrials.eu), checked 10 November 2026. Ask the study team whether a trial fits you.

No phaseTaking people
Long-term Evaluation of the SIMEOX Device at Home in Non-cystic Fibrosis Bronchiectasis
Where
Abbeville, Aix-en-Provence, Albi, Amiens, Angers, Annecy, Aressy, Brest, Cherbourg, Compiègne, Contamine-sur-Arve, Créteil, Dieulefit, Grenoble, Hyères, La Rochelle, Le Kremlin-Bicêtre, Le Puy-en-Velay, Libourne, Limoges, Lyon, Marseille, Montivilliers, Montpellier, Nice, Nîmes, Paris, Pau, Perpignan, Poitiers, Reims, Rennes, Roscoff, Rouen, Saint-Quentin, Suresnes, Tarbes, Toulouse, Troyes, Vannes
Age
18 years and over
People
468 worldwide
Run by
Physio-Assist
See details and how to joinNCT06487273
Phase 2Not yet taking people in France
A Study to Access Activity and Safety with SAR445399 Compared with Placebo in Participants Aged 18 to 80 Years of Age with Non-Cystic Fibrosis Bronchiectasis
Where
Amiens Cedex 1, Lyon Cedex 04, Pessac
Age
18 years and over
People
41 worldwide
Run by
Sanofi-Aventis Recherche & Developpement
See details and how to join2025-523403-29-00 · EU 2025-523403-29-00
No phaseTaking people
PERCE-MUCO: Perceptions and Expectations of People With Cystic Fibrosis Regarding a Change in Treatment
Where
Caen, Giens, Grenoble, Lille, Lyon, Montpellier, Paris, Reims, Rennes, Roscoff, Rouen, Vannes
Age
18 years and over
People
343
Run by
Fondation Ildys
See details and how to joinNCT07885410
No phaseTaking people
Development of Non-Invasive Prenatal Diagnosis for Single Gene Disorders
Where
Paris
Age
18 years and over
People
550
Run by
Assistance Publique - Hôpitaux de Paris
See details and how to joinNCT06147414
Phase 2Taking people
Dose Range Finding, Efficacy, and Safety Study of Nebulized CSL787 in Adults With Non-cystic Fibrosis Bronchiectasis (NCFB)
Where
Amiens Cedex 1, Angers, Brest, Marseille, Paris, Pessac Cedex, Toulouse, Tours
Age
18 years to 85 years
People
180 worldwide
Run by
CSL Behring
See details and how to joinNCT07048262 · EU 2024-518821-13-00
No phaseNot yet taking people in France
Reproducibility of Continuous Glucose Monitoring (CGM) in the Assessment of Glucose Metabolism Disorders in Children With Cystic Fibrosis
Where
Bron
Age
10 years to 17 years
People
30
Run by
Hospices Civils de Lyon
See details and how to joinNCT07851831
Phase 2Taking people
Safety, Tolerability, Pharmacokinetics, and Preliminary Efficacy of SPL84 in Patients with Cystic Fibrosis
Where
Montpellier
Age
18 years and over
People
30 worldwide
Run by
Splisense Ltd.
See details and how to join2024-511184-28-00 · EU 2024-511184-28-00
No phaseTaking people
French Validation of the AdT-Physio Scale
Where
Caen
Age
18 years to 100 years
People
121
Run by
Pole Sante Grace de Dieu
See details and how to joinNCT06273566
Phase 2Taking people
Comparison of Two Antibiotic Regimens for the Treatment of Early Airways Infection With PA in Adults With Bronchiectasis
Where
Amiens, Bordeaux, Brest, Cergy-Pontoise, Créteil, Lyon, Marseille, Nantes, Nice, Paris, Suresnes, Toulouse, Versailles, Villefranche-sur-Saône
Age
18 years and over
People
196
Run by
Centre Hospitalier Intercommunal Creteil
See details and how to joinNCT06368804
Phase 3Not yet taking people in France
Impact of discontinuation of long-term macrolides in stable Non Cystic Fibrosis Bronchiectasis : a multicenter randomized controlled trial
Where
Amiens Cedex 1, Brest, Caen, Creteil, Créteil, Le Chesnay Rocquencourt, Lille, Lyon Cedex 04, Marseille, Nantes, Nice, Paris, Pessac, Pontoise, Rouen, St Denis Cedex, Suresnes, Toulouse
Age
18 years and over
People
185
Run by
Centre Hospitalier Intercommunal Creteil
See details and how to join2025-521493-33-00 · EU 2025-521493-33-00
No phaseTaking people
Intestine-lung Axis of Cystic Fibrosis Patients Treated With the Combination Elexacaftor/Tezacaftor/Ivacaftor
Where
Bordeaux, Grenoble, Lille, Limoges, Lyon, Marseille, Montpellier, Nancy, Nice, Paris, Roscoff, Rouen, Toulouse
Age
6 years to 17 years
People
253
Run by
University Hospital, Bordeaux
See details and how to joinNCT05937815
Phase 2Not yet taking people in France
Safety and Efficacy of VX-828/Deutivacaftor Combination Therapy With and Without Tezacaftor in Subjects With Cystic Fibrosis
Where
Lille, Montpellier Cedex 5, Paris, Pierre-Bénite, Roscoff
Age
18 years and over
People
80 worldwide
Run by
Vertex Pharmaceuticals Inc.
See details and how to join2025-523400-72-00 · EU 2025-523400-72-00
No phaseTaking people
Pharmacokinetics of Antibiotics in Patients With Cystic Fibrosis Trated With Elexacaftor/Tezacaftor/Ivacaftor (ETI)
Where
Roscoff
Age
12 years and over
People
30
Run by
Fondation Ildys
See details and how to joinNCT07629986
No phaseTaking people
Correction of Nonsense Mutations in Cystic Fibrosis
Where
Amiens, Bron, Lille, Marseille, Montpellier, Paris, Strasbourg
Age
8 years and over
People
85
Run by
University Hospital, Lille
See details and how to joinNCT03670472
Phase 3Enrolling by invitation
Evaluation of Long-Term Safety and Efficacy of Vanzacaftor/Tezacaftor/Deutivacaftor in Cystic Fibrosis Participants 1 Year of Age and Older
Where
Bron, Paris
Age
1 year to 17 years
People
174 worldwide
Run by
Vertex Pharmaceuticals Incorporated
See details and how to joinNCT05844449 · EU 2022-503081-74-00
No phaseTaking people
Prevalence of Exercise-induced Ventilatory Limitation and Associated Factors in Patients With Cystic Fibrosis Receiving Elexacaftor-Tezacaftor-Ivacaftor
Where
Lille
Age
18 years and over
People
130
Run by
University Hospital, Lille
See details and how to joinNCT07314229
No phaseTaking people
Establishment of a Primary Epididymal Cell Model From Epididymal Samples to Study CFTR Gene Regulation
Where
Brest
Age
18 years and over
People
20
Run by
University Hospital, Brest
See details and how to joinNCT06045702
No phaseTaking people
A Cohort for Inflammatory Respiratory Diseases: From Phenotyping to Personalised Medicine
Where
Reims
Age
18 years and over
People
470
Run by
CHU de Reims
See details and how to joinNCT07274631
No phaseTaking people
Population Pharmacokinetics of Elexacaftor-tezacaftor-ivacaftor in a Paediatric Population
Where
Bron
Age
2 years to 17 years
People
150
Run by
Hospices Civils de Lyon
See details and how to joinNCT07303621
No phaseTaking people
Study of the Prevalence of Active/Passive Smoking and Vaping Among Patients With Cystic Fibrosis
Where
Strasbourg
Age
18 years and over
People
100
Run by
University Hospital, Strasbourg, France
See details and how to joinNCT07342920
No phaseTaking people
Impact of a Coordinated Dietetic-adapted Physical Activity Program on the Percentage of Lean Body Mass in Adults With Cystic Fibrosis Treated With Elexacaftor-Tezacaftor-Ivacaftor: Multicentre Randomised Controlled Trial
Where
Angers, Roscoff, Tours, Vannes
Age
18 years and over
People
100
Run by
University Hospital, Tours
See details and how to joinNCT06457451
No phaseTaking people
Physical Activity Profile and Sedentary Behaviour in Adults With Cystic Fibrosis
Where
Pierre-Bénite
Age
18 years to 65 years
People
270
Run by
Hospices Civils de Lyon
See details and how to joinNCT06507956
No phaseTaking people
Cellular Markers in Treated or Untreated Non-tuberculous Mycobacterial Respiratory Infection in Patients With Cystic Fibrosis
Where
Montpellier
Age
18 years and over
People
76
Run by
University Hospital, Montpellier
See details and how to joinNCT06602869
No phaseTaking people
Oral Health Status of Cystic Fibrosis Patients. An Online Survey in Collaboration With the Vaincre la Mucoviscidose Patient Association.
Where
Ivry-sur-Seine
Age
18 years and over
People
400
Run by
Assistance Publique - Hôpitaux de Paris
See details and how to joinNCT06356246
No phaseTaking people
A Usability Validation of the MuCopilot Mobile Application, a Digital Tool for the Unsupervised Objective Assessment of Cystic Fibrosis
Where
Rouen
Age
18 years and over
People
17
Run by
Ad scientiam
See details and how to joinNCT06132048