Cystic fibrosis trials in United States

In United States 83 Also abroad 188

83 trials · From ClinicalTrials.gov, checked 12 November 2026. Ask the study team whether a trial fits you.

No phaseTaking people
Sinus Disease in Young Children With Cystic Fibrosis
Where
Aurora, Charlottesville, Cincinnati, Colchester, Iowa City, Kansas City
Age
2 years to 8 years
People
80
Run by
University of California, Los Angeles
See details and how to joinNCT06191640
Phase 1Taking people
Dorzagliatin in Pancreatic Insufficient Cystic Fibrosis
Where
Philadelphia
Age
18 years and over
People
15
Run by
Michael R. Rickels, MD, MS
See details and how to joinNCT06995651
No phaseTaking people
Hormonal Responses to a Mixed Meal in People With Cystic Fibrosis
Where
Cincinnati
Age
18 years to 45 years
People
61
Run by
University of Cincinnati
See details and how to joinNCT06163482
No phaseTaking people
Remote Sputum Collection in Cystic Fibrosis
Where
Baltimore, Denver, Philadelphia, Spokane
Age
18 years and over
People
150
Run by
University of Pennsylvania
See details and how to joinNCT06950892
No phaseEnrolling by invitation
Glucose Metabolism in Cystic Fibrosis Related Diabetes (CFRD)
Where
Birmingham
Age
21 years to 75 years
People
30
Run by
University of Alabama at Birmingham
See details and how to joinNCT07102043
No phaseTaking people
Continuous Glucose Monitoring and OGTT Screen for Cystic Fibrosis Related Diabetes in Cystic Fibrosis
Where
Milwaukee
Age
18 years and over
People
30
Run by
Medical College of Wisconsin
See details and how to joinNCT06560463
No phaseNot yet taking people in United States
Rethinking Early Airway Clearence Therapies
Where
Ann Arbor, Atlanta, Aurora, Baltimore, Birmingham, Boston, Chapel Hill, Charleston, Charlottesville, Chicago, Cincinnati, Cleveland, Columbus, Dallas, Dayton, Houston, Indianapolis, Iowa City, Kansas City, Los Angeles, Madison, Milwaukee, Minneapolis, Orange, Palo Alto, Philadelphia, Pittsburgh, Portland, Richmond, Rochester, Seattle, Spokane, St Louis, St. Petersburg, Tucson
Age
3 years to 16 years
People
405 worldwide
Run by
Nicole Hamblett
See details and how to joinNCT07696338
Phase 2Not yet taking people in United States
Verapamil Effect in Cystic Fibrosis-related Dysglycemia
Where
Boston, Providence
Age
14 years and over
People
30
Run by
Rhode Island Hospital
See details and how to joinNCT07688070
No phaseTaking people
Study to Evaluate Biological & Clinical Effects of Significantly Corrected CFTR Function in Infants & Young Children
Where
Ann Arbor, Aurora, Birmingham, Boston, Buffalo, Burlington, Charlottesville, Cincinnati, Columbus, Dallas, Fort Worth, Grand Rapids, Hershey, Houston, Indianapolis, Iowa City, Jacksonville, Kansas City, Madison, Miami, Minneapolis, New York, Oklahoma City, Orlando, Palo Alto, Philadelphia, Pittsburgh, Portland, Salt Lake City, Seattle, St Louis, Syracuse, Valhalla
Age
Up to 10 years
People
210
Run by
Sonya Heltshe
See details and how to joinNCT04509050
Phase 4Taking people
Standardizing Treatments for Pulmonary Exacerbations - Aminoglycoside Study
Where
Akron, Ann Arbor, Atlanta, Baltimore, Billings, Birmingham, Boise, Boston, Charleston, Chicago, Cincinnati, Cleveland, Columbus, Dallas, Dayton, Fort Worth, Gainesville, Grand Rapids, Hollywood, Indianapolis, Iowa City, Jacksonville, Kansas City, La Jolla, Lebanon, Long Beach, Louisville, Madison, Miami, Morgantown, Morristown, Nashville, New Brunswick, New York, Oklahoma City, Orange, Peoria, Philadelphia, Pittsburgh, Portland, Richmond, Sacramento, Seattle, Spokane, St Louis, St. Petersburg, Toledo, Tucson, Valhalla, Washington D.C., Worcester
Age
6 years and over
People
730 worldwide
Run by
Chris Goss
See details and how to joinNCT05548283
Phase 2Taking people
4D-710 in Adult Patients With Cystic Fibrosis
Where
Baltimore, Birmingham, Boston, Chapel Hill, Charleston, Chicago, Cleveland, Columbus, Dallas, Denver, Gainesville, Hershey, Kansas City, Miami, Philadelphia, Richmond, San Francisco, Seattle, Tucson
Age
18 years and over
People
30
Run by
4D Molecular Therapeutics
See details and how to joinNCT05248230
No phaseTaking people
Quantitation and Spatial Registration of Airways Dysfunction With Dynamic 19F MRI in Cystic Fibrosis
Where
Chapel Hill
Age
18 years to 99 years
People
30
Run by
University of North Carolina, Chapel Hill
See details and how to joinNCT06057714
No phaseTaking people
19F MRI in Healthy Children and Children With Mild Cystic Fibrosis Lung Disease
Where
Chapel Hill
Age
6 years to 17 years
People
15
Run by
University of North Carolina, Chapel Hill
See details and how to joinNCT06066723
No phaseTaking people
Gastrointestinal Response of Pediatric Cystic Fibrosis Patients on Mediterranean Diet
Where
Lebanon, Manchester
Age
3 years to 18 years
People
20
Run by
Dartmouth-Hitchcock Medical Center
See details and how to joinNCT07223255
No phaseTaking people
Study to Enable New Diagnostics for Pulmonary Microbes in People With CF
Where
Columbus, Dallas, La Jolla, Milwaukee, Minneapolis, Omaha, Philadelphia, Pittsburgh, St Louis
Age
16 years and over
People
300
Run by
Chris Goss
See details and how to joinNCT07312734
No phaseTaking people
Evaluation of Ventilation Defects Downstream of Mucus Plugs in Patients With Muco-Obstructive Lung Disease
Where
Kansas City
Age
18 years to 65 years
People
8
Run by
University of Kansas Medical Center
See details and how to joinNCT06985225
No phaseTaking people
FEED-Cystic Fibrosis (FEED-CF)
Where
Atlanta
Age
18 years and over
People
60
Run by
Emory University
See details and how to joinNCT05766774
Phase 4Taking people
Ensuring Access to Optimal Therapy in CF: The ENACT Study
Where
Birmingham, Little Rock, Seattle
Age
3 years and over
People
100
Run by
Arkansas Children's Hospital Research Institute
See details and how to joinNCT07148739
No phaseTaking people
Rare CFTR Mutation Cell Collection Protocol (RARE)
Where
Birmingham
Age
17 years and over
People
500
Run by
George Solomon
See details and how to joinNCT03161808
No phaseTaking people
Role of Body Fat Distribution in Metabolic and Pulmonary Decline in Cystic Fibrosis (ORBIT-CF)
Where
Atlanta, Birmingham
Age
16 years and over
People
90
Run by
Emory University
See details and how to joinNCT04002882
Phase 2Taking people
GLP-1 Agonist Therapy in Cystic Fibrosis-Related Glucose Intolerance
Where
Aurora, Philadelphia
Age
18 years and over
People
30
Run by
University of Pennsylvania
See details and how to joinNCT04731272
Phase 2Taking people
Safety, Tolerability and Efficacy Study of ARCT-032 in People With Cystic Fibrosis
Where
Boston, Charleston, Cleveland, Hollywood, Little Rock, Los Angeles, Nashville, Northfield, San Antonio, Seattle, St Louis, Tucson, Washington D.C.
Age
18 years and over
People
33 worldwide
Run by
Arcturus Therapeutics, Inc.
See details and how to joinNCT06747858 · EU 2024-517663-23-01
Phase 1Taking people
A Study Assessing KB407 for the Treatment of Cystic Fibrosis
Where
Boise, Gainesville, Hawthorne, New York, Northfield, Winston-Salem
Age
18 years and over
People
20
Run by
Krystal Biotech, Inc.
See details and how to joinNCT05504837
No phaseTaking people
Routine Validation and Reproducibility Testing of Laboratory Assays and Research Techniques Used for Endocrine, Cardiometabolic, and Musculoskeletal Disorder Research (VALD)
Where
Columbia
Age
18 years to 100 years
People
100
Run by
Bettina Mittendorfer
See details and how to joinNCT07083557
Phase 1Taking people
Hyperpolarized 129Xe MR Imaging of Lung Function in Healthy Volunteers and Subjects With Pulmonary Disease
Where
Kansas City
Age
3 years and over
People
260
Run by
Mario Castro, MD, MPH
See details and how to joinNCT04624490