Diabetic eye disease: open trials in United States

47 open trials have a site in United States. Registry data; only the trial team decides who can take part.

NCT06629649
Implementing AI-based Glaucoma Screening Within Federally Qualified Health Centers
Trial Treatment · University of Alabama at Birmingham
Department of Ophthalmology and Visual Sciences, University of Alabama at Birmingham, Birmingham
Registry updated 2026-11-06
NCT07867080
A Phase 3 Trial for Intravitreal Injection of 4D-150 in Adults With Diabetic Macular Edema (DME).
Trial Treatment · Phase 3 · 4D Molecular Therapeutics
West Texas Retina Consultants, Abilene · Asheville Eye Associates - Retina Division, Asheville · Retina Specialists of Colorado - Aurora, Aurora · Austin Retina Associates, Austin · Austin Research Center for Retina, Austin · Austin Clinical Research, Austin · Mid Atlantic Retina, Bethlehem · Envision Ocular, LLC, Bloomfield · Midwest Eye Institute, Carmel · North Carolina Retina Associates - Cary Office, Cary · The Retina Group of Washington, Chevy Chase · Retina Consultants of Southern Colorado P.C., Colorado Springs · Texas Retina Associate, Dallas · Southwest Retina Consultants, Durango · NJ Retina, Edison · Retina Vitreous Center, Edmund · Retina Associates, Ltd., Elmhurst · The Retina Partners, Encino · The Retina Group of Washington, Fairfax · Retina Group of Florida, Fort Lauderdale · Retina Consultants of Orange County, Fullerton · Coastal Eye- Greenwich, Greenwich · Cumberland Valley Retina Consultants, Hagerstown · Mid Atlantic Retina Specialist, Hagerstown · Texas Retina Center, Houston · Retina Associates of Southern California, Huntington Beach · Retina Consultants of Texas - Katy, Katy · University Retina and Macula Associates PC - Lemont, Lemont · Piedmont Eye Center, Lynchburg · Mississippi Retina Associates, Madison · Retina Associates of Cleveland, Middleburg Heights · Tennessee Retina, Nashville · NYU Langone Health, New York · Retina Vitreous Surgeons of CNY, PC, New York · Illinois Retina Associates, Oak Park · Florida Retina Institute, Orlando · Retinal Specialty Institute, Pensacola · Mid Atlantic Retina - Philadelphia, Philadelphia · Fort Lauderdale Eye Institute (FLEI)-Plantation, Plantation · EyeHealth Northwest, Portland · Black Hills Regional Eye Institute, Rapid City · Sierra Eye Associates, Reno · Retinal Consultants Medical Group, Inc., Sacramento · Retina Consultants San Diego, San Diego · Retina Institute of New England, San Mateo · Research Network Arizona, Scottsdale · Deep Blue Retina Clinical Research PLLC, Southaven · Springfield Clinic, Springfield · The Retina Institute, St Louis · Retina Vitreous Associates of Florida, Tampa · Retina Consultants of Texas, The Woodlands · Tyler Retina Consultants, Tyler · North Carolina Retina Associates (Wake Forest), Wake Forest · Bay Area Retina Associates - Walnut Creek, Walnut Creek · Retina Institute of New England, PC, Waterford · Eye Clinic of Wisconsin, Wausau · Vitreoretinal Consultants of New York (VRCNY), Westbury
Registry updated 2026-11-05
NCT07705555
A Clinical Trial of MK-8748 Compared to Aflibercept in Participants With Diabetic Macular Edema (MK-8748-004)
Trial Treatment · Phase 3 · Merck Sharp & Dohme LLC
Austin Retina Associates (Site 0008), Austin · Retina Consultants of Texas (Site 0001), Bellaire · Envision Ocular, LLC (Site 0039), Bloomfield · Charleston Neuroscience Institute (Site 0087), Bluffton · Midwest Eye Institute (Site 0113), Carmel · Retina Consultants (Site 0104), Charleston · Mid Atlantic Retina (Site 0048), Cherry Hill · Retina Specialists of Colorado (Site 0068), Denver · Palmetto Retina Center (Site 0063), Florence · Vitreo Retinal Associates (Site 0042), Gainesville · Associated Retina Consultants, Ltd (Site 0084), Gilbert · Global Research Management (Site 0066), Glendale · Mid Atlantic Retina (Site 0062), Hagerstown · Southeastern Retina Associates PC (Site 0071), Johnson City · Southeastern Retina Associates PC (Site 0018), Knoxville · Retina Associates LLC (Site 0024), Lenexa · Mississippi Retina Associates, P.A. (Site 0061), Madison · Retina Consultants (Site 0065), Manchester · Charleston Neuroscience Institute (Site 0022), Mt. Pleasant · Retina Care Specialists (Site 0095), Palm Beach Gardens · Retina Associates of Western NY, PC (Site 0038), Rochester · Retinal Consultants Medical Group (Site 0013), Sacramento · Austin Retina Associates (Site 0080), San Marcos · Retina Consultants of Texas (Site 0029), Schertz · Retina Vitreous Associates of Florida (Site 0034), Tampa · Retina Specialists (Site 0074), Towson · North Carolina Retina Associates (Site 0064), Wake Forest · Palmetto Retina Center (Site 0014), West Columbia · Florida Retina Institute (Site 0105), Wildwood
Registry updated 2026-11-03
NCT07705607
A Clinical Trial of MK-8748 Compared to Aflibercept in Participants With Diabetic Macular Edema (MK-8748-005)
Trial Treatment · Phase 3 · Merck Sharp & Dohme LLC
Palmetto Retina Center (Site 0073), Aiken · Texas Retina (Site 0051), Arlington · Charleston Neuroscience Institute (Site 0090), Beaufort · Associated Vitreoretinal and Uveitis Consultants (Site 0099), Carmel · Charleston Neuroscience Institute (Site 0076), Charleston · Texas Retina Associates (Site 0055), Fort Worth · North Carolina Retina Associates (Site 0122), Greenville · Cumberland Valley Retina Consultants (Site 0003), Hagerstown · Graystone Eye (Site 0059), Hickory · Retina Consultants of Texas - Katy/Cinco Ranch (Site 0100), Katy · Retina Consultants of South Carolina (Site 0026), Ladson · Retina-Vitreous Surgeons of Central NY (Site 0021), Liverpool · South Coast Retina Center (Site 0121), Long Beach · Florida Retina Institute (Site 0035), Orlando · Retina Center of Texas (Site 0096), Southlake · Retina Vitreous Associates of Florida (Site 0036), St. Petersburg · Retina Group of New England (Site 0101), Waterford · Wolfe Eye Clinic (Site 0044), West Des Moines · Piedmont Retina Specialists (Site 0049), Winston-Salem · Center for Retina and Macular Disease (Site 0047), Winter Haven
Registry updated 2026-11-03
NCT07734844
A Study to Evaluate the Efficacy and Safety of Tabirafusp Tedromer Compared to Aflibercept in Participants With DME - ALTO
Trial Treatment · Phase 3 · Kodiak Sciences Inc
Kodiak Research Center, Amarillo · Kodiak Research Center, Arlington · Kodiak Research Center, Austin · Kodiak Research Center, Bakersfield · Kodiak Research Center, Beaufort · Kodiak Research Center, Bellaire · Kodiak Research Center, Bellevue · Kodiak Research Center, Cary · Kodiak Research Center, Charleston · Kodiak Research Center, Elmhurst · Kodiak Research Center, Fort Lauderdale · Kodiak Research Center, Fort Worth · Kodiak Research Center, Glendale · Kodiak Research Center, Greensboro · Kodiak Research Center, Hagerstown · Kodiak Research Center, Hauppauge · Kodiak Research Center, Hickory · Kodiak Research Center, Katy · Kodiak Research Center, Ladson · Kodiak Research Center, Lynchburg · Kodiak Research Center, Madison · Kodiak Research Center, Modesto · Kodiak Research Center, Mt. Pleasant · Kodiak Research Center, Oxnard · Kodiak Research Center, Pasadena · Kodiak Research Center, Plano · Kodiak Research Center, Redlands · Kodiak Research Center, Rochester · Kodiak Research Center, Round Rock · Kodiak Research Center, Sacramento · Kodiak Research Center, Saint Louis Park · Kodiak Research Center, San Antonio · Kodiak Research Center, Schertz · Kodiak Research Center, Scottsdale · Kodiak Research Center, Sioux Falls · Kodiak Research Center, St. Petersburg · Kodiak Research Center, The Woodlands · Kodiak Research Center, Wake Forest · Kodiak Research Center, Waterford · Kodiak Research Center, West Columbia · Kodiak Research Center, Winston-Salem · Kodiak Research Center, Winter Haven
Registry updated 2026-11-03
NCT07592273
Surabgene Lomparvovec Administered in the Suprachoroidal Space in Adult Participants With Diabetic Retinopathy Without Center-Involved Diabetic Macular Edema
Trial Treatment · Phase 2/3 · AbbVie
Southeast Retina Center /ID# 274739, Augusta · Austin Research Center for Retina /ID# 276101, Austin · California Retina Consultants - Bakersfield /ID# 282990, Bakersfield · Retina and Vitreous of Texas /ID# 283051, Bellaire · Retina-Vitreous Associates Medical Group - Beverly Hills /ID# 282995, Beverly Hills · Retina Center Of New Jersey /ID# 283088, Bloomfield · Star Retina /ID# 276513, Burleson · Retinal Diagnostic Center /ID# 275055, Campbell · Charleston Neuroscience Institute - Charleston /ID# 275047, Charleston · Illinois Retina Associates S.C /ID# 283048, Chicago · Texas Retina Associates - Dallas /ID# 276117, Dallas · Southwest Retina Research Center /ID# 276094, Durango · The Retina Partners /ID# 274741, Encino · Mid Atlantic Retina Specialists - Hagerstown /ID# 274725, Hagerstown · Florida Retina Consultants - Lakeland /ID# 275012, Lakeland · Colorado Retina Associates /ID# 283006, Lakewood · University Retina - Lemont /ID# 283021, Lemont · Retina Associates - Lenexa /ID# 283004, Lenexa · Advanced Vision Surgery Center /ID# 275017, Longmont · Barnet Dulaney Perkins Eye Center - Mesa /ID# 283000, Mesa · Retina Associates Of Cleveland - Middleburg Heights Office /ID# 275985, Middleburg Heights · Northern California Retina Vitreous Associates /ID# 282994, Mountain View · Wagner Macula & Retina Center - Norfolk /ID# 275021, Norfolk · Florida Retina Institute - Orlando /ID# 283034, Orlando · California Eye Specialists Medical Group /ID# 274705, Pasadena · Retina Speciality Institute /ID# 274996, Pensacola · Retinal Consultants Of Arizona - Phoenix - North /ID# 283407, Phoenix · Maine Eye Center - Marginal Way Campus /ID# 275039, Portland · Retina Northwest /ID# 283232, Portland · Retina Consultants San Diego /ID# 274748, Poway · Sierra Eye Associates /ID# 274737, Reno · Retinal Consultants - Sacramento - Greenback Lane /ID# 283018, Sacramento · Vistar Eye Center - Salem /ID# 282879, Salem · West Coast Retinal Medical Group /ID# 283007, San Francisco · California Retina Consultants - Santa Barbara /ID# 283050, Santa Barbara · Retina Macula Institute of Arizona /ID# 282881, Scottsdale · Springfield Clinic - First /ID# 283028, Springfield · Macula Retina Vitreous Center - Torrance /ID# 282878, Torrance · Bay Area Retina Associates /ID# 275032, Walnut Creek
Registry updated 2026-10-29
NCT06321302
A Study to Test Whether BI 764524 Helps People With an Eye Condition Called Diabetic Retinopathy
Trial Treatment · Phase 2 · Boehringer Ingelheim
Retina Consultants of Hawaii, ‘Aiea · Retina Research Center PLLC, Austin · Austin Retina Associates, Austin · Austin Clinical Research, LLC, Austin · California Retina Consultants-Bakersfield-65523, Bakersfield · Retina-Vitreous Associates Medical Group, Beverly Hills · Retinal Diagnostic Center, Campbell · University Hospitals Cleveland Medical Center*, Cleveland · The Retina Partners, Encino · Lugene Eye Institute, Glendale · Long Island Vitreoretinal Consultants, Great Neck · Cumberland Valley Retina Consultants, Hagerstown · Retina Associates of Southern California, Huntington Beach · Florida Retina Institute, Jacksonville · Retina Consultants of Texas, Katy · Charleston Neuroscience Institute - Ladson, Ladson · Florida Retina Consultants, Lakeland · Colorado Retina Associates, Lakewood · Retina Vitreous Surgeons of Central NY, PC, Liverpool · Valley Retina Institute, PA, McAllen · Tennessee Retina, Nashville · Byers Eye Institute, Palo Alto · California Eye Specialists Medical Group, Inc., Pasadena · Associated Retina Consultants, Ltd., Phoenix · EyeHealth Northwest, Portland · Maine Eye Center, Portland · Austin Retina Associates, Round Rock · Retinal Consultants Medical Group, Sacramento · Retina Associates of Utah, Salt Lake City · Medical Center Ophthalmology Associates, San Antonio · Retina Consultants of Texas, San Antonio · California Retina Consultants-Santa Maria-65510, Santa Maria · Retina Consultants of Texas - Schertz, Schertz · Deep Blue Retina Clinical Research PLLC, Southaven · East Florida Eye Institute, Stuart · NJRetina, Teaneck · Bay Area Retina Associates - Walnut Creek, Walnut Creek · Retina Group of New England, PC, Waterford · Center for Retina and Macular Disease, Winter Haven
Registry updated 2026-10-28
NCT07812090
A Randomized, Phase 2 Study of Oral BGE-102 in Participants With Center-Involved Diabetic Macular Edema
Trial Treatment · Phase 2 · BioAge Labs, Inc.
Abilene · Austin · Bakersfield · Cary · Fort Myers · Glendale · Houston · Ladson · Laredo · McAllen · Mountain View · San Antonio · South Miami · The Woodlands · Wake Forest · West Monroe
Registry updated 2026-10-27
NCT01496625
National Eye Institute Biorepository for Retinal Diseases
Research · National Eye Institute (NEI)
National Institutes of Health Clinical Center, Bethesda
Registry updated 2026-10-26
NCT03403699
Human iPSC for Repair of Vasodegenerative Vessels in Diabetic Retinopathy
Research · University of Alabama at Birmingham
University of Alabama at Birmingham, Birmingham
Registry updated 2026-10-26
NCT07567833
Longitudinal Study of Retinal Function in Eyes Treated for Diabetic Macular Edema With Anti-VEGF Agents
Trial Treatment · Phase 4 · Jaeb Center for Health Research
Southeast Retina Center, P.C., Augusta · Retina Consultants of Texas, Beaumont · Boston Medical Center Corporation, Boston · Henry Ford Health System, Detroit · Retina Consultants of Southern California, Huntington Beach · Retina-Vitreous Consultants, Inc., Monroeville · Mayo Clinic, Rochester · Pittsburgh Clinical Trial Consortium, Sewickley
Registry updated 2026-10-23
NCT07891910
Iopidine to Decrease Intraocular Pressure Rise After Injections
Trial Treatment · Phase 4 · Retina Consultants of Delmarva
Retina Consultants of Delmarva, Easton
Registry updated 2026-10-23
NCT06763952
Leveraging Artificial Intelligence to Prevent Vision Loss From Diabetes
Trial Treatment · University of Wisconsin, Madison
UW School of Medicine and Public Health, Madison
Registry updated 2026-10-22
NCT03713268
Intraoperative OCT Guidance of Intraocular Surgery II
Research · Duke University
Duke University Eye Center, Durham
Registry updated 2026-10-19
NCT05147701
Safety of Cultured Allogeneic Adult Umbilical Cord or Placental Derived Mesenchymal Stem Cell Exosomes for NAION
Trial Treatment · Phase 1 · The Foundation for Orthopaedics and Regenerative Medicine
Prodromos Stem Cell Institute, Naples
Registry updated 2026-10-16
NCT06962839
A Study to Test Whether BI 1815368 Helps People With an Eye Condition Called Diabetic Macular Edema
Trial Treatment · Phase 2 · Boehringer Ingelheim
Win Retina, Arcadia · Southeast Retina Center, PC, Augusta · Austin Clinical Research, LLC, Austin · Austin Research Center for Retina, PLLC, Austin · Austin Retina Associates, Austin · Retina Consultants of Texas - Beaumont, Beaumont · Associated Vitreoretinal and Uveitis Consultants, Carmel · Retina Consultants, PLLC, Charleston · Cleveland Clinic, Cleveland · Texas Retina Associates, Dallas · Connecticut Eye Consultants, PC, Danbury · Verum Research, LLC, Eugene · Retina Group of Florida - Fort Lauderdale Retina Center, Fort Lauderdale · Retina Consultants of Carolina, P.A., Greenville · Cumberland Valley Retina Consultants, Hagerstown · Retina Associates of Southern California, Huntington Beach · Florida Retina Institute, Jacksonville Southside, Jacksonville · University of Kansas Medical Center, Kansas City · Colorado Retina Associates, Lakewood · Piedmont Eye Center, Lynchburg · Retinal Consultants Medical Group, Inc, Modesto · Tennessee Retina, Nashville · Eye Research Foundation, Newport Beach · Doheny Eye Center UCLA Arcadia, Pasadena · Arizona Retina & Vitreous Research, Central Phoenix, Phoenix · Advanced Research Institute, Pompano Beach · Retina Consultants of San Diego, Poway · Sierra Eye Associates, Reno · Retinal Consultants of San Antonio, San Antonio · Medical Center Ophthalmology Associates, San Antonio · West Coast Retina Medical Group, Inc., San Francisco · Retina Center of Texas, Southlake · East Florida Eye Institute, Stuart · Retina Consultants of Texas, The Woodlands · North Carolina Retina Associates, Wake Forest · Center for Retina and Macular Disease, Winter Haven
Registry updated 2026-10-16
NCT07553429
A Study in People With Diabetic Macular Edema to Test How Well Different Doses of BI 3812465 Are Tolerated
Trial Treatment · Phase 1/2 · Boehringer Ingelheim
Win Retina, Arcadia · Austin Clinical Research, LLC, Austin · Retina Consultants of Texas-Bellaire-67493, Bellaire · Retina-Vitreous Associates Medical Group, Beverly Hills · Cleveland Clinic, Cleveland · Verum Research, LLC, Eugene · Emerson Clinical Research Institute, Falls Church · Red River Research Partners, LLC, Fargo · Retina Group of Florida - Fort Myers Retina Center, Fort Myers · Global Research Management, Glendale · Retina Associates of Southern California, Huntington Beach · Florida Retina Consultants, Lakeland · Valley Retina Institute, PA, McAllen · Tennessee Retina, Nashville · Ophthalmic Consultants of Long Island, Oceanside · California Retina Consultants-Oxnard-70187, Oxnard · Associated Retina Consultants, Ltd., Phoenix · EyeHealth Northwest, Portland · Retinal Consultants Medical Group, Sacramento · Retina Consultants of Texas, San Antonio · Medical Center Ophthalmology Associates, San Antonio · Research Network Arizona, Scottsdale · East Florida Eye Institute, Stuart · Retina Consultants of Texas-The Woodlands-67575, The Woodlands · North Carolina Retina Associates, Wake Forest · Bay Area Retina Associates - Walnut Creek, Walnut Creek · Retina Group of New England, PC, Waterford · Strategic Clinical Research Group, Willow Park
Registry updated 2026-10-14
NCT07588100
A Study to Investigate the Safety, Tolerability, and Pharmacokinetics of RO7663498 Following Intravitreal Administration in Participants With Diabetic Retinopathy
Trial Treatment · Phase 1 · Hoffmann-La Roche
Ohio State Havener Eye Institute;Ophthalmology Research, Columbus · Global Research Management, Glendale · University Retina and Macula Associates, PC, Oak Forest · Medical Center Ophthalmology Associates, San Antonio
Registry updated 2026-10-13
NCT07864480
Continuous Delivery of Ranibizumab Via the Port Delivery System for Proliferative Diabetic Retinopathy-related Vitreous Hemorrhage With Pars Plana Vitrectomy and Limited PRP.
Trial Treatment · Phase 4 · Southeast Retina Center, Georgia
Southeast Retina Center, Augusta
Registry updated 2026-10-13
NCT07425522
A Study to Evaluate the Safety, Tolerability, Pharmacodynamics, and Pharmacokinetics of RO7823653 in Participants With Diabetic Macular Edema (DME)
Trial Treatment · Phase 1 · Genentech, Inc.
Retina Research Institute of Texas, Abilene · Austin Clinical Research, LLC, Austin · Wilmer Eye Institute, Baltimore · Retina-Vitreous Associates Medical Group, Beverly Hills · Erie Retina Research, LLC - 300 State St, Erie · Charles Retina Institute, Germantown · Piedmont Eye Center, Lynchburg · Associated Retina Consultants - Peoria - DocTrials - PPDS, Peoria · Wills Eye Hospital, Philadelphia · Retina Consultants of Texas Westover Hills Retina Center, San Antonio · Retina Vitreous Associates of Florida, St. Petersburg · Bay Area Retina Specialists Medical Group - Vestrum - PPDS, Walnut Creek
Registry updated 2026-10-09
NCT07383701
Lactiplantibacillus Plantarum 299v Probiotic Supplementation in Patients With Diabetic Macular Edema
Trial Treatment · Phase 2 · Massachusetts Eye and Ear Infirmary
Mass Eye and Ear, Boston
Registry updated 2026-09-30
NCT03403686
Liver X Receptor (LXR) as a Novel Therapeutic Target in Diabetic Retinopathy (DR)
Research · University of Alabama at Birmingham
University of Alabama at Birmingham, Birmingham
Registry updated 2026-09-28
NCT07843849
Corticosteroid for Diabetic Macular Edema (DME) Study
Trial Treatment · Phase 4 · Vanderbilt University Medical Center
Vanderbilt Eye Institute, Nashville
Registry updated 2026-09-28
NCT07844317
Pivotal Trial for an Automated AI-based System for Detection of Diabetic Retinopathy
Research · Digital Diagnostics, Inc.
Rovia Site Network, Jacksonville
Registry updated 2026-09-28
NCT05463289
ACCESS 2: AI for pediatriC diabetiC Eye examS Study 2
Trial Treatment · Johns Hopkins University
Johns Hopkins Pediatric Diabetes Center, Baltimore
Registry updated 2026-09-23

All Diabetic eye disease trials and the map

This page is not medical advice. Talk to your doctor before contacting a trial.

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