Diabetic eye disease trials in United States

In United States 47 Also abroad 142

47 trials · From ClinicalTrials.gov, checked 12 November 2026. Ask the study team whether a trial fits you.

Phase 3Taking people
Faricimab + PRP vs. Vitrectomy + Endolaser for Treatment of PDR
Where
Atlanta, Augusta, Austin, Baltimore, Bellaire, Boston, Carmel, Chapel Hill, Chicago, Dallas, Edmond, Houston, Huntington Beach, Indianapolis, Jacksonville, Lakeland, Lexington, Loma Linda, Lubbock, Monroeville, Oak Park, Orlando, Overland, Rochester, Saint Louis Park, Sandy Springs, San Francisco, Santa Barbara, St Louis, Tampa, West Des Moines, West Monroe
Age
18 years and over
People
426
Run by
Jaeb Center for Health Research
See details and how to joinNCT06790784
No phaseTaking people
Clinical Applications of Advanced Ophthalmic Imaging
Where
Miami
Age
18 years to 99 years
People
5,000
Run by
University of Miami
See details and how to joinNCT03135327
Phase 1Taking people
Phase I Study to Assess the Safety and Efficacy of OCU200 for Center-Involved Diabetic Macular Edema (DME)
Where
Bellaire, Deerfield Beach, Erie, La Crosse, Southlake
Age
18 years and over
People
24
Run by
Ocugen
See details and how to joinNCT05802329
No phaseTaking people
Biomarker of Diabetic Retinopathy
Where
Carmel, Indianapolis
Age
18 years and over
People
192
Run by
Indiana University
See details and how to joinNCT05079399
No phaseNot yet taking people in United States
Video Intervention to Improve Understanding of Diabetic Retinopathy at Zuckerberg San Francisco General Hospital and Trauma Center
Where
San Francisco
Age
18 years and over
People
150
Run by
University of California, San Francisco
See details and how to joinNCT07519707
No phaseTaking people
Optical Coherence Tomography Angiography in Subjects With Retinal Vascular Disease
Where
Baltimore
Age
18 years to 99 years
People
1,050
Run by
Johns Hopkins University
See details and how to joinNCT04505618
No phaseTaking people
Village-Integrated Eye Worker Trial II
Where
San Francisco
Age
60 years and over
People
60,200
Run by
University of California, San Francisco
See details and how to joinNCT03752840
Phase 4Enrolling by invitation
Pre-operative Vabysmo in Patients With Non-clearing Vitreous Hemorrhage Secondary to Proliferative Diabetic Retinopathy
Where
Aurora
Age
18 years and over
People
100
Run by
University of Colorado, Denver
See details and how to joinNCT06191094
No phaseEnrolling by invitation
I-TRUST: Implementation of Teleophthalmology in Rural Health Systems Study
Where
Madison
Age
18 years and over
People
10
Run by
University of Wisconsin, Madison
See details and how to joinNCT05254535
Early phase 1Taking people
The Role of Occupational Therapy for Improving Medication Management for Persons With AMD, DR and Glaucoma
Where
Worcester
Age
50 years to 100 years
People
50
Run by
MCPHS University
See details and how to joinNCT06593405
No phaseTaking people
Strategies for Improving Linkage-to-Care After Eye Disease Screening
Where
San Francisco
Age
60 years and over
People
3,000
Run by
University of California, San Francisco
See details and how to joinNCT06943599
Phase 2Taking people
Sleep, Diabetic Retinopathy and Melatonin
Where
Chicago
Age
40 years to 65 years
People
42
Run by
University of Illinois Chicago
See details and how to joinNCT04547439
Early phase 1Enrolling by invitation
Treating Early Stage Diabetic Retinopathy
Where
Decatur
Age
30 years to 80 years
People
244
Run by
VA Office of Research and Development
See details and how to joinNCT05132660
Phase 4Enrolling by invitation
Study Evaluating the Efficacy and Safety of Chloroprocaine HCl Ophthalmic Gel 3% vs Proparacaine Ophthalmic Solution 0.5% Plus Subconjunctival Lidocaine in Patients Undergoing Intravitreal Injections
Where
Tyler
Age
18 years and over
People
236
Run by
Harrow Inc
See details and how to joinNCT07456826
Phase 3Taking people
A Study to Evaluate the Efficacy and Safety of OTX-TKI (Axitinib Implant) in Participants With Non-Proliferative Diabetic Retinopathy
Where
Hagerstown
Age
18 years and over
People
930
Run by
Ocular Therapeutix, Inc.
See details and how to joinNCT07235085
Phase 1/2Taking people
Kamuvudine-9 (K9) in Diabetic Macular Edema
Where
Roanoke
Age
18 years and over
People
10
Run by
Dr. Bryan Strelow
See details and how to joinNCT07458061
No phaseTaking people
Using Implementation Science to Adapt a Targeted Transportation Intervention for Patients With Diabetic Retinopathy (PRONTO-EYE)
Where
Chicago
Age
18 years and over
People
60
Run by
University of Illinois Chicago
See details and how to joinNCT07296952
Early phase 1Taking people
Feasibility and Safety of MB-102 in Ocular Angiography as Compared to Fluorescein Sodium
Where
Ann Arbor
Age
18 years and over
People
10
Run by
MediBeacon
See details and how to joinNCT04008121
No phaseTaking people
Assessment of AI Program 'DRISTi' as a Screening Tool
Where
Oxford, Raleigh
Age
21 years and over
People
900
Run by
Artelus AI
See details and how to joinNCT07222293
Phase 4Taking people
High Dose Aflibercept in Diabetic Macular Edema in Patients With Previous Vitrectomy
Where
Fullerton
Age
21 years and over
People
15
Run by
Retina Consultants of Orange County
See details and how to joinNCT06662994
Phase 2Taking people
Phase 2 Trial of RGX-314 in Adults With Center Involved - Diabetic Macular Edema (CI - DME)
Where
Reno
Age
25 years to 89 years
People
18
Run by
Sierra Eye Associates
See details and how to joinNCT06942520
No phaseTaking people
A Prospective Observational Study to Assess the Reliability and Validity of the MLSDT
Where
Dallas
Age
18 years and over
People
30
Run by
Nanoscope Therapeutics Inc.
See details and how to joinNCT06805474