Endometrial cancer trials in United States

In United States 199 Also abroad 395

199 trials · From ClinicalTrials.gov, checked 12 November 2026. Ask the study team whether a trial fits you.

Phase 3Taking people
Study to Assess the Efficacy and Safety of Rina-S Compared to Treatment of Investigator's Choice in Participants With Endometrial Cancer
Where
Arlington, Atlanta, Austin, Baltimore, Baton Rouge, Bedford, Charlotte, Charlottesville, Cincinnati, Concord, Coon Rapids, Dallas, Danbury, Decatur, Durham, Edina, Eugene, Evanston, Fort Worth, Gastonia, Grand Rapids, Happy Valley, Harlingen, Hartford, Irvine, Maple Grove, Maplewood, McAllen, Minneapolis, Mobile, Morristown, New Orleans, New York, Norwalk, Phoenix, Portland, San Antonio, San Francisco, Sarasota, Shreveport, St Louis, St. Petersburg, Summit, Tampa, Teaneck, Tigard, Vancouver, Waco, Washington D.C., Weslaco, Westminster, Winston-Salem, Woodbury, Worcester
Age
18 years and over
People
660 worldwide
Run by
Genmab
See details and how to joinNCT07166094
Phase 3Taking people
A Study to Investigate Mocertatug Rezetecan Compared With Chemotherapy in Participants With Endometrial Cancer After Platinum-based Chemotherapy and Immunotherapy (BEHOLD-Endometrial01)
Where
Birmingham, Charlottesville, Omaha, Sugar Land
Age
18 years and over
People
600 worldwide
Run by
GlaxoSmithKline
See details and how to joinNCT07286331 · EU 2025-523362-25-00
Phase 2Taking people
Targeted Therapy Directed by Genetic Testing in Treating Patients With Locally Advanced or Advanced Solid Tumors, The ComboMATCH Screening Trial
Where
Abilene, ‘Aiea, Albuquerque, Allentown, Altoona, Anaconda, Anchorage, Ankeny, Ann Arbor, Appleton, Arroyo Grande, Asheboro, Ashland, Athens, Augusta, Aurora, Aventura, Avon, Baltimore, Barrington, Battle Creek, Beachwood, Bellevue, Belpre, Bemidji, Berlin, Bethesda, Bethlehem, Billings, Birmingham, Bismarck, Bloomington, Boiling Springs, Boise, Boston, Bozeman, Brewer, Brighton, Bristol, Bryn Mawr, Buffalo, Burlington, Caldwell, Canton, Cape Girardeau, Carmichael, Carterville, Carthage, Cedar Rapids, Centerville, Centralia, Charleston, Charlottesville, Chelsea, Chesterfield, Chicago, Chillicothe, Cincinnati, City of Saint Peters, Cleveland, Clinton, Coeur d'Alene, Collierville, Columbia, Columbus, Commack, Coon Rapids, Coral Gables, Creve Coeur, Crown Point, Crystal Lake, Cumberland, Dallas, Danville, Dayton, Dearborn, Decatur, Deerfield Beach, Deer River, DeKalb, Delaware, Des Moines, Dixon, Downers Grove, Dublin, Duluth, Durham, Easley, East Stroudsburg, Eau Claire, Edina, Edmonds, Effingham, Elgin, Elk Grove, Encinitas, Erie, Escanaba, Eureka, Evanston, ‘Ewa Beach, Fairfax, Falls Church, Fargo, Farmington, Farmington Hills, Findlay, Flemington, Flint, Fort Collins, Fort Lauderdale, Franklin, Fruitland, Gainesville, Galesburg, Geneva, Germantown, Glenview, Goldsboro, Goodyear, Grafton, Grand Rapids, Grayslake, Great Falls, Greeley, Green Bay, Greensboro, Greensburg, Greenville, Greer, Grenada, Grove City, Gulfport, Harrison, Harvey, Hazel Crest, Hazleton, Hibbing, Highland Park, High Point, Honolulu, Houston, Huntington, Issaquah, Jacksonville, Janesville, Johnson City, Jonesboro, Kalamazoo, Kalispell, Kenosha, Kettering, Kewanee, Kingman, Kingsport, Lacey, La Crosse, La Jolla, Lake Forest, Lakewood, Lancaster, Lansing, Las Vegas, Lexington, Libertyville, Livingston, Livonia, Long Branch, Los Angeles, Loveland, Lubbock, Macomb, Madison, Manistique, Mansfield, Maple Grove, Maplewood, Marinette, Marion, Marshfield, Martinez, Marysville, Mattoon, Mayfield Heights, Maywood, Mechanicsburg, Media, Memphis, Mentor, Meridian, Metairie, Miami, Michigan City, Middleburg Heights, Middletown, Milwaukee, Mineola, Minneapolis, Minocqua, Missoula, Mobile, Monroeville, Morgantown, Mount Vernon, Mukwonago, Muskegon, Nampa, Nashville, Nassau Bay, Neenah, New Albany, Newark, Newberg, New Brunswick, New Lenox, New London, Newnan, New Orleans, New Richmond, New York, Niles, Normal, North Miami, Norton Shores, Oak Lawn, Oconomowoc, Oconto Falls, O'Fallon, Oklahoma City, Omaha, Ontario, Orange, Oregon City, Orland Park, Oshkosh, Ottawa, Oxford, Paducah, Palo Alto, Paoli, Park Ridge, Pekin, Pennington, Peoria, Perrysburg, Peru, Philadelphia, Phoenix, Pickerington, Pittsburgh, Plantation, Pontiac, Portland, Portsmouth, Post Falls, Princeton, Providence, Racine, Raleigh, Rapid City, Reed City, Reidsville, Reno, Renton, Rice Lake, Richmond, Roanoke, Rochester, Rockford, Rocklin, Rolla, Royal Oak, Sacramento, Saginaw, Sainte Genevieve, Saint Joseph, Saint Louis Park, Saint Paul, San Diego, Sandpoint, Sandstone, San Francisco, Santa Monica, Sayre, Scarborough, Seattle, Seneca, Sewell, Shawano, Sheboygan, Shiloh, Sioux Falls, Somerville, South Bend, Southhaven, South Hill, South Portland, Springfield, Stevens Point, St Louis, Stoneham, Sturgeon Bay, Sugar Land, Sullivan, Summit, Syracuse, Tawas City, Temple, The Bronx, The Woodlands, Toledo, Toms River, Traverse City, Troy, Twin Falls, Two Rivers, Urbana, Virginia, Walla Walla, Walnut Creek, Warrenville, Washington, Waukee, Waukesha, Waupaca, Wauwatosa, West Allis, West Branch, Westerville, Weston, Whittier, Willow Grove, Winston-Salem, Woodland, Wynnewood, Wyoming, Yakima, Youngstown, Ypsilanti, Zanesville, Zion
People
2,900 worldwide
Run by
National Cancer Institute (NCI)
See details and how to joinNCT05564377
Phase 1Taking people
Study of RGT-490 in Patients With PIK3CA-Mutated Advanced Solid Tumors
Where
Fairfax, Houston, Los Angeles, Pittsburgh, San Antonio
Age
18 years and over
People
63
Run by
Regor Pharmaceuticals Inc.
See details and how to joinNCT07524322
Phase 1/2Taking people
CR-002 in Adult Participants With Locally Advanced or Metastatic Solid Tumors
Where
Austin, Dallas, Fairfax
Age
18 years and over
People
219
Run by
Crescent Biopharma, Inc.
See details and how to joinNCT07909031 · EU 2026-527289-54-00
Phase 1/2Taking people
EIK1005-002: A Clinical Research Study Evaluating EIK1005, a Werner Helicase Inhibitor, as Monotherapy and in Combination With Pembrolizumab in Participants With Advanced Solid Tumors Including Microsatellite Instability High (MSI-H) Tumors
Where
Doral, Fort Worth, Hialeah, Houston, Lake Success, Los Angeles, Morristown, New York, Plantation, Tamarac
Age
18 years and over
People
160 worldwide
Run by
Eikon Therapeutics
See details and how to joinNCT07262619 · EU 2026-525248-13-00
Phase 3Taking people
Symbiotic-GYN-18: A Study to Learn About the Study Medicine Called PF-08634404 in Combination With Chemotherapy in Adult Participants With Advanced or Recurrent MMR-proficient Endometrial Cancer
Where
Abilene, Albany, Amarillo, Austin, Centerville, Chesapeake, Coon Rapids, Edina, El Paso, Happy Valley, Harlingen, Hudson, Irving, Jupiter, Maple Grove, Maplewood, McAllen, Midland, Nashville, Newport News, Norfolk, Odessa, Orlando, Portland, Reno, Suffolk, Tigard, Vancouver, Waco, Weslaco, White Plains, Wichita Falls, Williamsburg, Woodbury
Age
18 years and over
People
600 worldwide
Run by
Pfizer
See details and how to joinNCT07578649 · EU 2026-525584-40-00
Phase 1Taking people
A Phase 1 Study of LNCB74 in Advanced Solid Tumors
Where
Boston, Buffalo, Cleveland, Edgewood, Falls Church, Hackensack, Houston, Nashville, Newport Beach, New York, Philadelphia, Pittsburgh, Salt Lake City, San Antonio, St Louis
Age
18 years and over
People
145
Run by
LigaChem Biosciences, Inc.
See details and how to joinNCT06774963
No phaseTaking people
Avera Cancer Sequencing and Analytics Protocol (ASAP)
Where
Aberdeen, Marshall, Mitchell, Pierre, Sioux Falls, Yankton
Age
18 years and over
People
25,000
Run by
Avera McKennan Hospital & University Health Center
See details and how to joinNCT05142033
Phase 1Taking people
A Study of MGC026 in Participants With Advanced Solid Tumors
Where
Grand Rapids, Houston, Lake Success, Los Angeles, Portland, West Valley City
Age
18 years and over
People
394 worldwide
Run by
MacroGenics
See details and how to joinNCT06242470
Phase 1/2Taking people
A Phase 1/2 Trial of TER-2013 in Patients With Solid Tumors Harboring AKT/PI3K/PTEN Pathway Alterations
Where
Austin, Boston, Cleveland, Duarte, Fairfax, Houston, Huntersville, Irvine, Milwaukee, Nashville, Omaha, Orlando, Rochester, San Antonio, St Louis, West Valley City, Zion
Age
18 years and over
People
248 worldwide
Run by
Terremoto Biosciences Inc.
See details and how to joinNCT07109726
Phase 1Taking people
Testing Different Amounts of the Combination of Drugs M1774 and ZEN-3694 for the Treatment of Recurrent Ovarian and Endometrial Cancer
Where
Albuquerque, Augusta, Chicago, Cleveland, Columbus, Detroit, Iowa City, Milwaukee, Oklahoma City, Philadelphia, Providence
Age
18 years and over
People
65
Run by
National Cancer Institute (NCI)
See details and how to joinNCT05950464
Phase 3Taking people
A Study of Trastuzumab Deruxtecan Versus Standard of Care Chemotherapy for HER2-Expressing (IHC 3+/2+) Endometrial Cancer in Adjuvant Setting
Where
Bedford, Cincinnati, Coon Rapids, Fort Lauderdale, Fort Wayne, Miami, Miami Beach, Orlando, Pinehurst, Pittsburgh, San Antonio, Shreveport, Sioux Falls
Age
18 years and over
People
710 worldwide
Run by
Daiichi Sankyo
See details and how to joinNCT07022483 · EU 2024-519444-33-00
Phase 1Taking people
A Phase 1/1B Study of ST-01156, a Small Molecule RBM39 Degrader, in Patients With Advanced Solid Malignancies
Where
Boston, Duarte, Houston, Newport Beach, New York
Age
16 years and over
People
171
Run by
SEED Therapeutics, Inc.
See details and how to joinNCT07197554
Phase 2Taking people
A Study of HER3-DXd in Subjects With Locally Advanced or Metastatic Solid Tumors
Where
Baltimore, Buffalo, Chicago, Duarte, Houston, Kissimmee, Nashville, New Haven, New York, Rockville, Saint Louis Park, Saint Paul, Seattle, St Louis
Age
18 years and over
People
740 worldwide
Run by
Daiichi Sankyo
See details and how to joinNCT06172478 · EU 2023-507641-29-00
Phase 1/2Taking people
A Study to Evaluate the Efficacy and Safety of Ifinatamab Deruxtecan (I-DXd) in Subjects With Recurrent or Metastatic Solid Tumors (IDeate-PanTumor02)
Where
Amarillo, Chattanooga, Dallas, Fairfax, Germantown, Los Angeles, Minneapolis, Nashville, New York, Pearland, Salt Lake City, Skokie, Wenatchee, Westbury, White Plains, Whittier
Age
18 years and over
People
680 worldwide
Run by
Daiichi Sankyo
See details and how to joinNCT06330064 · EU 2023-509632-26-00
Phase 1Taking people
A Phase 1 Study to Evaluate OPB-201 in Recurrent Endometrial and Platinum-resistant Ovarian Cancer.
Where
Atlanta, Detroit, Houston, Minneapolis, San Francisco
Age
18 years and over
People
30
Run by
Outpace Bio, Inc.
See details and how to joinNCT07664735
Phase 1Taking people
A Phase 1 Study of the Safety and Tolerability of CTX-10726
Where
Greenville, Jacksonville, Lake Success, Nashville, Omaha, Phoenix, Pittsburgh, Rochester
Age
18 years and over
People
70
Run by
Compass Therapeutics
See details and how to joinNCT07419841
Phase 1Taking people
Phase 1 Study of STRO-006 in Adults With Refractory Solid Tumors That Are Recurrent or Metastatic
Where
Boston, Fairfax, Irving, Lubbock, Oklahoma City, Orlando
Age
18 years and over
People
285
Run by
Sutro Biopharma, Inc.
See details and how to joinNCT07807345
Phase 1/2Taking people
A Study of ART0380 for the Treatment of Advanced or Metastatic Solid Tumors
Where
Austin, Baton Rouge, Birmingham, Boston, Chattanooga, Cincinnati, Columbia, Dallas, Denver, East Syracuse, Fairfax, Flower Mound, Fort Myers, Hinsdale, Houston, Indianapolis, Jacksonville, Lake Success, Little Rock, Los Angeles, Maple Grove, Maumee, Memphis, Nashville, New York, Oklahoma City, Orlando, Philadelphia, Portland, Rochester, Salt Lake City, San Antonio, Santa Barbara, Santa Rosa, Sarasota, Scottsdale, Seattle, St Louis, Washington D.C., West Palm Beach
Age
18 years and over
People
542 worldwide
Run by
Artios Pharma Ltd
See details and how to joinNCT04657068
Phase 1Taking people
A Study of Mutant Selective-Inhibitor (CGT6297), in Patients With Advanced Solid Tumors
Where
Austin, Boston, Denver, East Brunswick, Fairfax, Los Angeles, Nashville, Palo Alto, Scottsdale, St Louis, Tampa, West Valley City
Age
18 years and over
People
90
Run by
Cogent Biosciences, Inc.
See details and how to joinNCT07383506
Phase 2Taking people
A Study to Estimate Early Clinical Efficacy Signals of GLP-1 Agonist Administration in Conjunction With Levonorgestrel Intrauterine Device in Obese Patients With Endometrioid Intraepithelial Neoplasia
Where
Gainesville
Age
18 years and over
People
20
Run by
University of Florida
See details and how to joinNCT07107334
Phase 2Taking people
Study of EV for Recurrent Endometrial Carcinoma
Where
Milwaukee
Age
18 years and over
People
12
Run by
William Bradley
See details and how to joinNCT07139977
No phaseTaking people
A Blended e-Health Intervention to Improve Fear of Progression in Women With Gynecologic or Breast Cancer
Where
Arcadia, Duarte, Huntington Beach, Irvine, Lancaster, Long Beach, Santa Clarita, Simi Valley, South Pasadena, Upland, West Covina
Age
18 years and over
People
126
Run by
City of Hope Medical Center
See details and how to joinNCT07741968
Phase 2Taking people
Radiation and TSR-042 (Dostarlimab) in People With Endometrial Cancer After They Receive Surgery
Where
Basking Ridge, Commack, Harrison, Middletown, Montvale, New York, Rockville Centre
Age
18 years and over
People
62
Run by
Memorial Sloan Kettering Cancer Center
See details and how to joinNCT04774419