Frontotemporal dementia trials in Canada

In Canada 13 Also abroad 110

13 trials · From ClinicalTrials.gov, checked 11 November 2026. Ask the study team whether a trial fits you.

Phase 1/2Taking people
Trial of ARO-MAPT-SC in Healthy Participants and Participants With Early Alzheimer's Disease or Primary Tauopathies
Where
East York, Montreal, Toronto
Age
18 years and over
People
160 worldwide
Run by
Arrowhead Pharmaceuticals
See details and how to joinNCT07221344
No phaseTaking people
ARTFL LEFFTDS Longitudinal Frontotemporal Lobar Degeneration (ALLFTD)
Where
Toronto, Vancouver
Age
18 years and over
People
2,100 worldwide
Run by
Mayo Clinic
See details and how to joinNCT04363684
No phaseEnrolling by invitation
Alzheimer's Disease Neuroimaging Initiative 4
Where
London, Toronto, Vancouver
Age
55 years to 90 years
People
1,500 worldwide
Run by
University of Southern California
See details and how to joinNCT05617014
No phaseTaking people
Effects of Probiotics in Amyotrophic Lateral Sclerosis-Frontotemporal Dementia Spectrum Disorder (ALS-FTDSD) Patients
Where
Fredericton, Montreal, Saskatoon
Age
18 years and over
People
150
Run by
Centre hospitalier de l'Université de Montréal (CHUM)
See details and how to joinNCT06051123
Phase 1/2Taking people
A Study to Evaluate the Safety and Effect of AVB-101, a Gene Therapy Product, in Subjects With a Genetic Sub-type of Frontotemporal Dementia (FTD-GRN)
Where
Toronto
Age
30 years to 75 years
People
18 worldwide
Run by
AviadoBio Ltd
See details and how to joinNCT06064890 · EU 2023-509444-10-00
Phase 2Taking people
Transcranial Direct Current Stimulation in the Treatment of Primary Progressive Aphasia
Where
Toronto
Age
50 years to 90 years
People
180 worldwide
Run by
Johns Hopkins University
See details and how to joinNCT05386394
No phaseTaking people
Comprehensive Assessment of Neurodegeneration and Dementia
Where
Calgary, Edmonton, Halifax, Hamilton, London, Montreal, Ottawa, Peterborough, Québec, Sherbrooke, Toronto, Vancouver, Victoria, Waterloo
Age
50 years to 90 years
People
1,573
Run by
McGill University
See details and how to joinNCT03402919
No phaseTaking people
Improving Prognostic Confidence in Neurodegenerative Diseases Causing Dementia Using Peripheral Biomarkers and Integrative Modeling
Where
North York, Toronto
Age
30 years to 95 years
People
500
Run by
University Health Network, Toronto
See details and how to joinNCT06529744
No phaseTaking people
Genetic Frontotemporal Dementia Initiative for Neurodevelopment
Where
London
Age
7 years to 17 years
People
200
Run by
Western University
See details and how to joinNCT05779813
No phaseTaking people
Diagnosing Frontotemporal Lobar Degeneration
Where
Toronto
Age
18 years to 90 years
People
100
Run by
University Health Network, Toronto
See details and how to joinNCT02964637
No phaseTaking people
Molecular Neuroimaging of Neuroinflammation in Neurodegenerative Dementias
Where
London
Age
30 years to 95 years
People
40
Run by
London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
See details and how to joinNCT02945774
No phaseTaking people
Investigating Genetic Status in Patients Presenting to Clinic
Where
London
Age
18 years and over
People
1,000
Run by
London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
See details and how to joinNCT05911932
Phase 4Taking people
Lemborexant for Insomnia in a Patient With Dementia: An N-of-1 Trial
Where
Halifax
People
1
Run by
Nova Scotia Health Authority
See details and how to joinNCT06093126