Hypertrophic cardiomyopathy: open trials in United Kingdom

14 open trials have a site in United Kingdom. Registry data; only the trial team decides who can take part.

NCT07023614
A Trial to Evaluate the Efficacy and Safety of Ninerafaxstat in Patients With Symptomatic Non-obstructive Hypertrophic Cardiomyopathy
Trial Treatment · Phase 2 · Imbria Pharmaceuticals, Inc.
Glasgow · London · Oxford
Registry updated 2026-10-26
NCT07054073
HCMR Re-Imaging Study
Research · Christopher Kramer
University Hospitals Birmingham NHS Foundation Trust, Birmingham · Barts Health NHS Trust, London
Registry updated 2026-10-16
NCT04848506
Open-label Extension Study to Evaluate the Long-term Safety and Tolerability of Aficamten in Adults With HCM
Trial Treatment · Phase 2/3 · Cytokinetics
Queen Elizabeth Hospital Birmingham, University Hospitals Birmingham NHS Foundation Trust, Birmingham · Ninewells Hospital and Medical School, Dundee · Glasgow Clinical Research Facility Neuroscience Institute, Glasgow · Liverpool Heart and Chest Hospital, Liverpool · St. George's University Hospitals NHS Foundation Trust, London · St. Bartholomew's Hospital, London · Royal Brompton Hospital, London · Oxford Centre for Clinical Magnetic Resonance Research (OCMR) Division of Cardiovascular Medicine Radcliffe Department of Medicine University of Oxford, Oxford
Registry updated 2026-10-13
NCT07865364
Coronary Sinus Reducer Objective Impact on SymptoMs, Ischaemia and miCrovascular Resistance in Non-obstructive Hypertrophic CardioMyopathy
Trial Treatment · Imperial College London
University Hospitals Bristol and Weston NHS Foundation Trust, Bristol · Liverpool Heart and Chest Hospital NHS Foundation Trust, Liverpool · Barts Health NHS Trust, London · Guy's and St Thomas' NHS Foundation Trust, London · Imperial College Healthcare NHS Trust, London · Oxford University Hospitals NHS Foundation Trust, Oxford · University Hospitals Dorset NHS Foundation Trust, Poole · Mid and South Essex NHS Foundation Trust, Westcliff-on-Sea
Registry updated 2026-10-08
NCT06092034
A Gene Therapy Study of RP-A501 in Male Patients With Danon Disease
Trial Treatment · Phase 2 · Rocket Pharmaceuticals Inc.
Great Ormond Street Hospital & UCL Institute of Cardiovascular Science, London
Registry updated 2026-10-06
NCT07454135
Mechanisms of Atrial Pathoelectrophysiology in HCM
Research · Guy's and St Thomas' NHS Foundation Trust
Guy's and St Thomas' NHS Foundation Trust, London
Registry updated 2026-09-11
NCT06409585
Cardiomyopathies and Heart Muscle Diseases: Cardiac Imaging in the Evaluation of Myocardial Fibrosis Transition
Research · University of Edinburgh
University of Edinburgh, Edinburgh
Registry updated 2026-08-26
NCT05489705
A Prospective Registry Study to Assess Real-world Patient Characteristics, Treatment Patterns, and Longitudinal Outcomes in Patients Receiving Mavacamten and Other Treatments for Symptomatic Obstructive Hypertrophic Cardiomyopathy (Obstructive-HCM)
Research · Bristol-Myers Squibb
Birmingham · University Hospital of Wales, Cardiff · Leeds General Infirmary, Leeds · Liverpool Heart and Chest Hospital, Liverpool · Imperial College Healthcare NHS Trust, London · London · University of Manchester, Manchester
Registry updated 2026-08-19
NCT07595354
Exercise Prescription in Children With Hypertrophic Cardiomyopathy
Trial Treatment · Alder Hey Children's NHS Foundation Trust
Alder Hey Children's Hospital, Liverpool
Registry updated 2026-05-19
NCT07381894
Multicentre Hypertrophic Cardiomyopathy Registry
Research · University of Manchester
University of Manchester, Manchester
Registry updated 2026-05-01
NCT07557498
Mavacamten Outcomes in Hypertrophic Cardiomyopathy (HCM) and the Associated Patient and Physician Experiences in the US
Research · Bristol-Myers Squibb
Adelphi Real World, Bollington
Registry updated 2026-04-29
NCT04612296
The Heart Hive - Cardiomyopathy Study
Research · Imperial College London
Imperial College London, London
Registry updated 2026-03-27
NCT07408427
Precision Pharmacogenetics and Genotype Class Based Prediction of Mavacamten Response in Obstructive Hypertrophic Cardiomyopathy
Research · University of Manchester
Manchester Centre for Genomic Medicine (MCGM), Multiple Locations
Registry updated 2026-02-13
NCT05750147
The SMARTER Cardiomyopathy Study
Research · Imperial College London
Guys St Thomas NHS Foundation Trust, London · Kings College Hospital, London
Registry updated 2024-03-06

All Hypertrophic cardiomyopathy trials and the map

This page is not medical advice. Talk to your doctor before contacting a trial.

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