Hypertrophic cardiomyopathy trials in United Kingdom

In United Kingdom 14 Also abroad 88

14 trials · From ClinicalTrials.gov, checked 11 November 2026. Ask the study team whether a trial fits you.

Phase 2Taking people
A Trial to Evaluate the Efficacy and Safety of Ninerafaxstat in Patients With Symptomatic Non-obstructive Hypertrophic Cardiomyopathy
Where
Glasgow, London, Oxford
Age
18 years and over
People
165 worldwide
Run by
Imbria Pharmaceuticals, Inc.
See details and how to joinNCT07023614
No phaseTaking people
HCMR Re-Imaging Study
Where
Birmingham, London
Age
18 years to 65 years
People
314 worldwide
Run by
Christopher Kramer
See details and how to joinNCT07054073
Phase 2/3Enrolling by invitation
Open-label Extension Study to Evaluate the Long-term Safety and Tolerability of Aficamten in Adults With HCM
Where
Birmingham, Dundee, Glasgow, Liverpool, London, Oxford
Age
18 years to 85 years
People
900 worldwide
Run by
Cytokinetics
See details and how to joinNCT04848506 · EU 2023-508963-58-00
No phaseNot yet taking people in United Kingdom
Coronary Sinus Reducer Objective Impact on SymptoMs, Ischaemia and miCrovascular Resistance in Non-obstructive Hypertrophic CardioMyopathy
Where
Bristol, Liverpool, London, Oxford, Poole, Westcliff-on-Sea
Age
18 years and over
People
50
Run by
Imperial College London
See details and how to joinNCT07865364
Phase 2Taking people
A Gene Therapy Study of RP-A501 in Male Patients With Danon Disease
Where
London
Age
8 years and over
People
18 worldwide
Run by
Rocket Pharmaceuticals Inc.
See details and how to joinNCT06092034
No phaseTaking people
Mechanisms of Atrial Pathoelectrophysiology in HCM
Where
London
Age
18 years to 80 years
People
40
Run by
Guy's and St Thomas' NHS Foundation Trust
See details and how to joinNCT07454135
No phaseTaking people
Cardiomyopathies and Heart Muscle Diseases: Cardiac Imaging in the Evaluation of Myocardial Fibrosis Transition
Where
Edinburgh
Age
30 years to 90 years
People
290
Run by
University of Edinburgh
See details and how to joinNCT06409585
No phaseTaking people
A Prospective Registry Study to Assess Real-world Patient Characteristics, Treatment Patterns, and Longitudinal Outcomes in Patients Receiving Mavacamten and Other Treatments for Symptomatic Obstructive Hypertrophic Cardiomyopathy (Obstructive-HCM)
Where
Birmingham, Cardiff, Leeds, Liverpool, London, Manchester
Age
18 years and over
People
1,700 worldwide
Run by
Bristol-Myers Squibb
See details and how to joinNCT05489705
No phaseTaking people
Exercise Prescription in Children With Hypertrophic Cardiomyopathy
Where
Liverpool
Age
10 years to 18 years
People
10
Run by
Alder Hey Children's NHS Foundation Trust
See details and how to joinNCT07595354
No phaseTaking people
Multicentre Hypertrophic Cardiomyopathy Registry
Where
Manchester
Age
18 years to 99 years
People
2,500
Run by
University of Manchester
See details and how to joinNCT07381894
No phaseTaking people
Mavacamten Outcomes in Hypertrophic Cardiomyopathy (HCM) and the Associated Patient and Physician Experiences in the US
Where
Bollington
Age
18 years and over
People
362
Run by
Bristol-Myers Squibb
See details and how to joinNCT07557498
No phaseTaking people
The Heart Hive - Cardiomyopathy Study
Where
London
Age
18 years and over
People
10,000
Run by
Imperial College London
See details and how to joinNCT04612296
No phaseNot yet taking people in United Kingdom
Precision Pharmacogenetics and Genotype Class Based Prediction of Mavacamten Response in Obstructive Hypertrophic Cardiomyopathy
Where
Multiple Locations
Age
18 years to 99 years
People
140
Run by
University of Manchester
See details and how to joinNCT07408427
No phaseTaking people
The SMARTER Cardiomyopathy Study
Where
London
People
1,000
Run by
Imperial College London
See details and how to joinNCT05750147