Macular degeneration: open trials in Germany

23 open trials have a site in Germany. Registry data; only the trial team decides who can take part.

NCT06847542
A Study of 36-Week Refill Exchanges of Port Delivery System (PDS) With Ranibizumab in nAMD
Trial Treatment · Phase 3 · Hoffmann-La Roche
Klinikum Chemnitz gGmbH, Chemnitz · Universitaetsklinikum Duesseldorf AöR, Duesseldorf · Universitaetsmedizin Goettingen, Goettingen · Medizinische Hochschule Hannover, Hanover · Rostock University Medical Center, Rostock · Universitaetsklinikum Wuerzburg AöR, Wuerzburg
Registry updated 2026-11-06
NCT06541704
A Study Investigating Subcutaneously Administered Pozelimab in Combination With Cemdisiran or Cemdisiran Alone in Adult Participants With Geographic Atrophy
Trial Treatment · Phase 3 · Regeneron Pharmaceuticals
Charite Universitaetsmedizin Berlin KöR, Berlin · Universitaetsklinikum Bonn AöR, Bonn · Universitaetsklinikum Duesseldorf AöR, Duesseldorf · Augenzentrum Prof. Dr. Koch GmbH, Frankfurt am Main · Universitaetsmedizin Goettingen, Goettingen · University Medical Center Hamburg-Eppendorf, Hamburg · Universitaetsklinikum Heidelberg AöR, Heidelberg · Universitaet Des Saarlandes, Homburg · Klinikum der Stadt Ludwigshafen am Rhein gGmbH, Ludwigshafen Am Rhein · Universitaetsmedizin der Johannes Gutenberg-Universitaet Mainz KöR, Mainz · Universitaetsklinikum Giessen und Marburg GmbH, Marburg · Universitaetsklinikum Muenster AöR, Muenster · Augenzentrum Am St Franziskus-Hospital Muenster, Munster · Diakonie Klinikum Dietrich Bonhoeffer GmbH, Neubrandenburg · Knappschaftsklinikum Saar GmbH, Sulzbach · Universitaetsklinikum Ulm AoR, Ulm · Universitaetsklinikum Wuerzburg AöR, Wuerzburg
Registry updated 2026-11-05
NCT06635148
A Long-term Extension Study of JNJ-81201887 (AAVCAGsCD59) Parent Studies in Participants With Geographic Atrophy (GA) Secondary to Age-related Macular Degeneration (AMD)
Trial Treatment · Phase 2/3 · Janssen Research & Development, LLC
Universitätsklinikum Bonn AöR, Bonn · Universitaetsmedizin Goettingen, Goettingen · Medizinische Hochschule Hannover, Hanover · Universitaet Leipzig, Leipzig · Klinikum der Stadt Ludwigshafen am Rhein gGmbH, Ludwigshafen Am Rhein · Universitaetsklinikum Muenster AöR, Muenster · Augenzentrum Am St Franziskus-Hospital Muenster, Munster · Universitaetsklinikum Tuebingen AöR, Tuebingen
Registry updated 2026-11-03
NCT06924021
Age-Related Macular Degeneration Benchmark Imaging Dataset (ABID)
Research · University of Wisconsin, Madison
University of Bonn - Department of Ophthalmology, Bonn
Registry updated 2026-10-30
NCT07007065
Study to Assess the Injection Burden, Adverse Events, Change in Disease Activity, and Long-Term Preservation of Visual Acuity of Surabgene Lomparvovec in Adult Participants With Neovascular Age-Related Macular Degeneration (nAMD)
Trial Treatment · Phase 3 · AbbVie
Charite Universitaetsmedizin Berlin KöR, Berlin · Universitaetsklinikum Bonn AöR, Bonn · Medical Center- University of Freiburg, Freiburg im Breisgau · Universitaetsmedizin Goettingen, Goettingen · University Medical Center Hamburg-Eppendorf, Hamburg · Medizinische Hochschule Hannover, Hanover · Klinikum der Stadt Ludwigshafen am Rhein gGmbH, Ludwigshafen Am Rhein · Universitaetsklinikum Schleswig-Holstein AöR, Luebeck · Universitaet Muenster, Muenster · LMU Klinikum Muenchen AöR, Munich · Universitaetsklinikum Tuebingen AöR, Tuebingen · Universitaetsklinikum Ulm AoR, Ulm
Registry updated 2026-10-29
NCT03683251
Extension Study for the Port Delivery System With Ranibizumab (Portal)
Trial Treatment · Phase 3 · Hoffmann-La Roche
Universitaetsklinikum Bonn AöR, Bonn · University Hospital Cologne AöR, Cologne · Carl-Thiem-Klinikum Cottbus gGmbH, Cottbus · Medical Center- University of Freiburg, Freiburg im Breisgau · University Medical Center Hamburg-Eppendorf, Hamburg · Klinikum der Stadt Ludwigshafen am Rhein gGmbH, Ludwigshafen Am Rhein · Universitaet Muenster, Muenster · Ludwig-Maximilians-Universitaet Muenchen, Munich · Augenzentrum Am St Franziskus-Hospital Muenster, Munster · Knappschaftsklinikum Saar GmbH, Sulzbach · Universitaetsklinikum Tuebingen AöR, Tuebingen · Universitaetsklinikum Ulm AoR, Ulm
Registry updated 2026-10-27
NCT06659549
A Phase 2 Efficacy and Safety Study of GAL-101, 2% Ophthalmic Solution in Non-foveal Geographic Atrophy Secondary to Non-neovascular AMD
Trial Treatment · Phase 2 · Galimedix Therapeutics Inc
Universitaetsklinikum Bonn AöR, Bonn · Medical Center- University of Freiburg, Freiburg im Breisgau · Medizinische Hochschule Hannover, Hanover · Universitaetsklinikum Heidelberg AöR, Heidelberg · Diakonie Klinikum Dietrich Bonhoeffer GmbH, Neubrandenburg · Tübingen University Hospital, Tübingen · Universitaetsklinikum Ulm AoR, Ulm
Registry updated 2026-10-22
NCT07064759
Single Intravitreal (IVT) Injection of 4D-150 in Patients With Macular Neovascularization Secondary to Age-Related Macular Degeneration
Trial Treatment · Phase 3 · 4D Molecular Therapeutics
Internationale Innovative Ophthalmochirurgie GbR, Düsseldorf · Augenzentrum Frankfurt, Frankfurt · Dietrich Bonhoeffer Klinikum, Neubrandenburg
Registry updated 2026-10-19
NCT07441642
A Study to Investigate Efficacy and Safety of FWY003 Compared With Placebo in Participants With Geographic Atrophy Secondary to Age-related Macular Degeneration
Trial Treatment · Phase 2 · Novartis Pharmaceuticals
Bonn · Ludwigshafen · Münster · Tübingen
Registry updated 2026-10-13
NCT07440225
A Clinical Trial of EYE201/MK-8748 in People With Macular Degeneration (MK-8748-002)
Trial Treatment · Phase 2/3 · EyeBiotech Ltd.
Universitätsklinikum Hamburg Eppendorf Klinik und Poliklinik für Augenheilkunde, Hamburg · Augenzentrum am St. Franziskus-Hospital Münster, Münster
Registry updated 2026-10-02
NCT05481827
ORACLE: A Long-term Follow-up Study to Evaluate the Safety of GT005 in Participants With Geographic Atrophy Secondary to Age-related Macular Degeneration Treated in a Gyroscope-sponsored Antecedent Study
Trial Treatment · Phase 2 · Gyroscope Therapeutics Limited
Universitaetsklinikum Schleswig-Holstein AöR, Luebeck · Universitaetsklinikum Tuebingen AöR, Tuebingen
Registry updated 2026-09-28
NCT04663750
Vitrectomy, Subretinal Tissue Plasminogen Activator (TPA) and Intravitreal Gas for Submacular Haemorrhage Secondary to Exudative (Wet) Age-related Macular Degeneration (TIGER).
Trial Treatment · Phase 3 · King's College Hospital NHS Trust
Charite Universitaetsmedizin Berlin KöR, Berlin · Universitaetsklinikum Bonn AöR, Bonn · University Medical Center Hamburg-Eppendorf, Hamburg · Klinikum der Stadt Ludwigshafen am Rhein gGmbH, Ludwigshafen Am Rhein · Universitaetsklinikum Muenster AöR, Muenster · St. Franziskus-Hospital GmbH, Muenster · Klinikum rechts der Isar der TU Muenchen AöR, Munich · Ludwig Maximilian University Of Munich, Munich · Klinikum Der Landeshauptstadt Stuttgart gKAöR, Stuttgart · Knappschaftsklinikum Saar GmbH, Sulzbach · Universitaetsklinikum Ulm AoR, Ulm · Universitats Augenklinik Wurzburg, Würzburg
Registry updated 2026-09-11
NCT06659445
Study to Evaluate Efficacy and Safety of ONL1204 in Patients With GA Associated With AMD
Trial Treatment · Phase 2 · ONL Therapeutics
Universitaetsklinikum Aachen AöR, Aachen · Augen-Zentrum-Nordwest, Ahaus · Dr. med. Stefan Scholl und Prof. Dr. med. Albert J. Augustin Augenarztpraxis, Baden-Baden · Universitaetsklinikum Bonn AöR, Bonn · Internationale Innovative Ophthalmochirurgie GbR (I.I.O.), Duesseldorf · Augenzentrum Prof. Dr. Koch GmbH, Frankfurt am Main · Philipps-Universitaet Marburg, Marburg · Universitaetsklinikum Wuerzburg AöR, Wuerzburg
Registry updated 2026-09-10
NCT06990269
Phase 2 Study of ADX-038 in Participants With Geographic Atrophy
Trial Treatment · Phase 2 · ADARx Pharmaceuticals, Inc.
Universitaetsklinikum Bonn AöR, Bonn · Justus-Liebig-Universitaet Giessen, Giessen · University Hospital Cologne, Köln · Universitaetsmedizin der Johannes Gutenberg-Universitaet Mainz KöR, Mainz · Universitaetsklinikum Muenster AöR, Muenster · Ludwig-Maximilians-Universitaet Muenchen, Munich · Knappschaft Kliniken Saar GmbH, Sulzbach · Eberhard Karls Universitaet Tuebingen, Tuebingen
Registry updated 2026-09-03
NCT07531927
Safety and Clinical Applicability of Transcorneal Electrical Stimulation (TES) in Geographic Atrophy
Trial Treatment · Okuvision GmbH
Department of Ophthalmology, University Medical Center Hamburg-Eppendorf, Hamburg · Department of Ophthalmology, Ludwig-Maximilians-University Munich, München · Department of Ophthalmology, Klinikum Stuttgart, Stuttgart · Centre for Ophthalmology, University Hospital Tuebingen, Tübingen · Department of Ophthalmology, University Hospital Ulm, Ulm
Registry updated 2026-07-28
2025-523704-77-00
A clinical trial to learn more about the effects of FWY003 in people with geographic atrophy associated with age-related macular degeneration.
Trial Treatment · Phase 2 · Novartis Pharma AG
Universitaetsklinikum Bonn AöR, Bonn · Klinikum der Stadt Ludwigshafen am Rhein gGmbH, Ludwigshafen Am Rhein · Augenzentrum Am St Franziskus-Hospital Muenster, Munster · Universitaetsklinikum Tuebingen AöR, Tuebingen
Registry updated 2026-06-23
NCT07308639
DATA-INSIGHT is a Project That Looks at Health Data in Germany to Find Out How Many Patients Suffer From Eye Disease. The Project Also Explores New Ways to Collect and Use Publicly Available Healthcare Information.
Research · Bayer
Bayer Vital GmbH, Leverkusen
Registry updated 2026-06-22
2025-524575-22-00
A randomized double-masked, multicenter, 3 arm pivotal Phase 2/3 study to evaluate the efficacy and safety of intravitreal (IVT) EYE201/MK-8748 in participants with neovascular age-related macular degeneration (NVAMD)
Trial Treatment · Phase 2/3 · Eyebiotech Limited
Universitaetsklinikum Bonn AöR, Bonn · University Hospital Frankfurt, Frankfurt am Main · University Medical Center Hamburg-Eppendorf, Hamburg · Medizinische Hochschule Hannover, Hanover · Klinikum der Technischen Universitaet Muenchen (TUM Klinikum), Munich · Augenzentrum Am St Franziskus-Hospital Muenster, Munster · Universitaetsklinikum Tuebingen AöR, Tuebingen
Registry updated 2026-06-12
NCT07529041
Real-time Acoustic Biofeedback for Enhancing Fixation Stability: A Proof-of-concept Study to Improve Ophthalmic Imaging Diagnostic Quality
Trial Treatment · University Medical Center Goettingen
EKFZ Else Kroener Fresenius Center for Optogenetic Therapies, University Medical Center Goettingen, Göttingen
Registry updated 2026-04-14
NCT07515521
Enhanced Vision and Imaging Tests for Enabling Treatment Trials in Early and Intermediate AMD
Research · Maximilian Pfau
Department of Ophthalmology, University Hospital Bonn, Bonn
Registry updated 2026-04-07
NCT07164378
International Study of the SING IMT™ Prosthesis in Pseudophakic patiEnts With Stable Moderate to Profound Bilateral Central vIsion Impairment Due to adVancEd AMD / PERSPECTIVE Study
Trial Treatment · VisionCare, Inc.
Asklepios Augenklinik Nord-Heidberg, Hamburg · Augenklinik Sulzbach, Sulzbach · MVZ Augenklinik Petrisberg GmbH, Trier · Augenklinik und Poliklinik des Universitätsklinikums, Würzburg
Registry updated 2026-03-20
NCT06817915
This Project At LMU Looks At How Using AI 2nd Opinion Report to Analyze Retinal Eye Scans Impact Doctors' Decisions About Treatment for Patients with a Specific Eye Disease (nAMD)
Trial Treatment · Johannes Schiefelbein
LMU Klinikum, Munich
Registry updated 2025-02-10
NCT03999801
Long-term Follow-Up Study of RGX-314 and Fellow Eye Substudy
Trial Treatment · Phase 2 · AbbVie
Universitaetsklinikum Bonn AöR, Bonn · Medical Center- University of Freiburg, Freiburg im Breisgau · University Medical Center Hamburg-Eppendorf, Hamburg · Klinikum der Stadt Ludwigshafen am Rhein gGmbH, Ludwigshafen Am Rhein · Universitaet Muenster, Muenster · Universitaetsklinikum Ulm AoR, Ulm
Registry updated 2024-06-17

All Macular degeneration trials and the map

This page is not medical advice. Talk to your doctor before contacting a trial.

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