Migraine trials in United States

In United States 92 Also abroad 249

92 trials · From ClinicalTrials.gov, checked 12 November 2026. Ask the study team whether a trial fits you.

No phaseTaking people
Study to Assess the Real-World Effectiveness of Ubrogepant in Adult Participants When Treating During the Prodrome Phase of Migraine Attacks
Where
Aliso Viejo, Grand Island, Naperville
Age
18 years and over
People
189
Run by
AbbVie
See details and how to joinNCT07310290
No phaseTaking people
Unhide® Project: A Digital Health Platform to Collect Lifestyle Data for Brain Inflammation Research
Where
Delafield
Age
2 years and over
People
10,000
Run by
Brain Inflammation Collaborative
See details and how to joinNCT04806620
Phase 3Taking people
Effectiveness of Magnesium in Addition to Prochlorperazine for the Treatment of Migraines
Where
Oak Lawn
Age
18 years and over
People
100
Run by
Wake Forest University Health Sciences
See details and how to joinNCT06904287
No phaseTaking people
Investigating Brain Function in People With and Without Visual Snow Syndrome Using Adaptation to Visual Stimuli
Where
Minneapolis
Age
18 years to 60 years
People
100
Run by
University of Minnesota
See details and how to joinNCT06961864
Phase 4Taking people
Rimegepant as Preemptive Treatment for Predictable Trigger-Induced Migraine in Adult Patients in the US
Where
McLean
Age
18 years and over
People
60
Run by
Medstar Health Research Institute
See details and how to joinNCT07301008
No phaseTaking people
Observational Study to Assess Adverse Events When Adult Female Participants Are Treated With Ubrelvy (Ubrogepant) or Qulipta (Atogepant) During Pregnancy
Where
Durham
Age
18 years and over
People
1,884 worldwide
Run by
AbbVie
See details and how to joinNCT05158894
No phaseTaking people
Efficacy of Xeomin for Migraines in Patients With Traumatic Brain Injuries vs. Anomalous Health Incidents
Where
Bethesda
Age
18 years and over
People
60
Run by
Uniformed Services University of the Health Sciences
See details and how to joinNCT07267819
No phaseTaking people
Aimovig Pregnancy Exposure Registry
Where
Durham
Age
18 years to 99 years
People
2,842
Run by
Amgen
See details and how to joinNCT06150781
No phaseTaking people
Acceptance and Commitment Therapy to Improve Disability in Chronic Migraine
Where
Boston
Age
18 years to 65 years
People
40
Run by
Brigham and Women's Hospital
See details and how to joinNCT06795867
No phaseTaking people
Assessing Symptom and Mood Dynamics in Pain Using the Smartphone Application SOMA
Where
Providence
Age
18 years and over
People
800
Run by
Brown University
See details and how to joinNCT05754190
No phaseTaking people
Real-world Prospective Study on the Use of Anti-CGRP Drugs in Migraine
Where
Miami
Age
18 years and over
People
700 worldwide
Run by
Hospital Universitari Vall d'Hebron Research Institute
See details and how to joinNCT07159750
Phase 4Enrolling by invitation
Quality Improvement and Practice Based Research in Neurology Using the EMR
Where
Evanston
Age
18 years to 100 years
People
3,300
Run by
Endeavor Health
See details and how to joinNCT02670161
Phase 3Enrolling by invitation
Long-term Extension Study to Assess Adverse Events of Oral Atogepant Tablets in Pediatric Participants (6 to 17 Years of Age) With Migraine
Where
Amherst, Anaheim, Ann Arbor, Austin, Bountiful, Brunswick, Cincinnati, El Paso, Everett, Fort Collins, Franklin, Friendswood, Greensboro, Gulf Breeze, Homestead, Huntsville, Lafayette, Little Rock, Long Beach, Miami, Morristown, Nashville, Newburgh, New York, Oceanside, Oklahoma City, Overland Park, Papillion, Ridgeland, Salt Lake City, San Jose, Spring Hill, The Woodlands, Waxahachie, West Chester
Age
6 years to 17 years
People
650 worldwide
Run by
AbbVie
See details and how to joinNCT05707949 · EU 2022-501099-24-00
No phaseTaking people
Analysis of Headache Chronification With Imaging, Deep Phenotyping, and Proteomics
Where
Stanford
Age
18 years and over
People
700
Run by
Stanford University
See details and how to joinNCT03231241
Phase 3Enrolling by invitation
Long-term Extension Study to Assess Safety and Tolerability of Oral Ubrogepant Tablets for the Acute Treatment of Migraine in Pediatric Participants (Ages 6-17)
Where
Ames, Amherst, Anaheim, Annandale, Atlanta, Aurora, Austin, Baltimore, Beaumont, Bountiful, Boynton Beach, Brunswick, Burnsville, Centennial, Charleston, Charlotte, Chicago, Cincinnati, Colorado Springs, Columbus, Dallas, Decatur, El Paso, Everett, Fort Myers, Franklin, Fresno, Friendswood, Gainesville, Greenville, Greer, Gulf Breeze, Hialeah, Hickory, Hollywood, Homestead, Houston, Huntsville, Kerrville, Kingwood, Lakeland, Lampasas, Lexington, Little Rock, Long Beach, Los Angeles, Mansfield, Mequon, Meridian, Miami, Morristown, Mount Kisco, Nashua, Nashville, New York, Norfolk, Oceanside, Oklahoma City, Orange City, Orlando, Overland Park, Ozark, Palm Harbor, Papillion, Petal, Philadelphia, Plano, Port Jefferson Station, Portland, Richmond, Ridgeland, Runnemede, Salt Lake City, San Antonio, San Diego, San Jose, Saraland, Savannah, Scottdale, Smithfield, Spring Hill, Stamford, Stockbridge, Syracuse, Tampa, The Woodlands, Upland, Walnut Creek, Washington D.C., Waxahachie, West Chester, Weston, Wichita, Winter Park, Woodstock
Age
6 years to 17 years
People
1,200 worldwide
Run by
AbbVie
See details and how to joinNCT05127954
Phase 3Not yet taking people in United States
0.5% Bupivacaine Lower Cervical Intramuscular Injection vs IV Medications for Headache Treatment
Where
Gainesville
Age
18 years and over
People
100
Run by
HCA Florida North Florida Hospital
See details and how to joinNCT06937385
Phase 4Taking people
Qudexy XR for the Prevention of Migraine in Children 6 to 11 Years Old
Where
Ann Arbor, Aurora, Birmingham, Bridgeton, Cincinnati, Huntington, Jackson, La Jolla, Loxahatchee Groves, McAllen, Orlando, Portland, Springfield, Stamford, Tampa
Age
6 years to 11 years
People
132
Run by
Upsher-Smith Laboratories
See details and how to joinNCT04748601