Mild cognitive impairment trials in United States

In United States 203 Also abroad 457

203 trials · From ClinicalTrials.gov, checked 15 November 2026. Ask the study team whether a trial fits you.

No phaseTaking people
Superior Parietal iTBS for PD-MCI
Where
Charleston
Age
50 years to 85 years
People
30
Run by
Medical University of South Carolina
See details and how to joinNCT07701785
No phaseTaking people
Transcranial Photobiomodulation (tPBM) in Alzheimer's Disease Study
Where
Los Angeles
Age
55 years to 89 years
People
45
Run by
Cedars-Sinai Medical Center
See details and how to joinNCT07224607
Phase 2Taking people
Biomarker-based Trial of NPC-1 for Alzheimer's Pathology
Where
Boston
Age
55 years and over
People
40
Run by
Massachusetts General Hospital
See details and how to joinNCT07236190
No phaseNot yet taking people in United States
A Postmarketing Study of LEQEMBI in Participants With Alzheimer's Disease
Where
Nutley
People
270
Run by
Eisai Inc.
See details and how to joinNCT07864623
No phaseTaking people
MCI Speech in Noise
Where
Lebanon
Age
55 years to 80 years
People
70
Run by
Dartmouth-Hitchcock Medical Center
See details and how to joinNCT06102486
No phaseNot yet taking people in United States
Personalized Closed-Loop Brain Stimulation for Patients With Mild Cognitive Impairment
Where
Baltimore
Age
45 years to 85 years
People
10
Run by
Johns Hopkins University
See details and how to joinNCT07512193
No phaseTaking people
Wake Forest Alzheimer's Disease Clinical Core
Where
Winston-Salem
Age
55 years and over
People
850
Run by
Wake Forest University Health Sciences
See details and how to joinNCT03140865
No phaseTaking people
NON-INVASIVE BRAIN STIMULATION FOR MEMORY LOSS IN EARLY ALZHEIMER'S DISEASE
Where
Houston
Age
55 years to 90 years
People
40
Run by
Chi-Ying (Roy) Lin
See details and how to joinNCT07667478
Phase 1/2Taking people
Digital STEADI Efficacy
Where
Atlanta
Age
50 years and over
People
300
Run by
Friendi.fi Corporation
See details and how to joinNCT07852650
Phase 2Not yet taking people in United States
Restoring Vascular and Insulin Function To Augment Anti-Amyloid Therapy in Alzheimer's Disease
Where
Winston-Salem
Age
55 years to 85 years
People
30
Run by
Wake Forest University Health Sciences
See details and how to joinNCT07756294
No phaseEnrolling by invitation
Alzheimer's Disease Neuroimaging Initiative 4
Where
Albany, Ann Arbor, Atlanta, Baltimore, Birmingham, Boston, Buffalo, Charleston, Chicago, Cleveland, Columbus, Dallas, Durham, Fairway, Gainesville, Houston, Indianapolis, Iowa City, Irvine, Jacksonville, La Jolla, Las Vegas, Lexington, Los Angeles, Madison, Miami, Miami Beach, Nashville, New Haven, New York, Orangeburg, Orlando, Palo Alto, Philadelphia, Phoenix, Pittsburgh, Portland, Providence, Rochester, San Antonio, San Francisco, St Louis, Sun City, Tampa, Tulsa, Walnut Creek, Washington D.C., Winston-Salem
Age
55 years to 90 years
People
1,500 worldwide
Run by
University of Southern California
See details and how to joinNCT05617014
No phaseTaking people
Disease Modifying Potential of 5mg of Melatonin on Cognition and Brain Health in Aging
Where
Iowa City
Age
56 years to 85 years
People
230
Run by
Natalie Denburg
See details and how to joinNCT03954899
No phaseNot yet taking people in United States
Jigsawdio Multisensory Platform for People With Mild Cognitive Impairment, Alzheimer's Disease, or Related Dementias
Where
College Station, Durham
Age
60 years and over
People
80
Run by
Callahan-Young LLC DBA Jigsawdio
See details and how to joinNCT07839286
Phase 1/2Not yet taking people in United States
2-Hydroxybenzylamine (2-HOBA) Study in Early Alzheimer's Patients
Where
Nashville
Age
55 years to 85 years
People
48
Run by
MTI Biotech Inc
See details and how to joinNCT06432166
No phaseNot yet taking people in United States
Virtual Outreach and Individualized Coaching Extension
Where
Atlanta
Age
65 years and over
People
50
Run by
Emory University
See details and how to joinNCT07836114
No phaseTaking people
Predicting Pre-dementia
Where
San Diego
Age
55 years and over
People
100
Run by
Prevention Research Consortium Corp.
See details and how to joinNCT07516119
No phaseTaking people
Music for Pain and Dementia
Where
New Haven
Age
50 years to 80 years
People
60
Run by
Yale University
See details and how to joinNCT07602283
No phaseTaking people
Comparing Two Acute Care Transition Programs for Older Adults and Their Family Caregivers
Where
Bermuda Run, High Point, North Wilkesboro, Winston-Salem
Age
18 years and over
People
2,560
Run by
Wake Forest University Health Sciences
See details and how to joinNCT07661355
No phaseTaking people
Microbiome in Aging of Gut and Brain
Where
Tampa
Age
18 years and over
People
700
Run by
University of South Florida
See details and how to joinNCT07799402
No phaseTaking people
Percepta for Cognitive Optimization
Where
Wilmington
Age
40 years to 85 years
People
154
Run by
Cerebrum DAO Association
See details and how to joinNCT07612449
No phaseNot yet taking people in United States
An Insole and Ankle Device for Monitoring Cognitive Decline in Individuals at Risk for Alzheimer's Disease and/or Alzheimer's Disease Related Dementias (AD/ADRD)
Where
Saint Paul
Age
55 years and over
People
150
Run by
HealthPartners Institute
See details and how to joinNCT07127133
No phaseTaking people
Determinants of Incident Stroke Cognitive Outcomes and Vascular Effects on RecoverY
Where
Ann Arbor, Baltimore, Boston, Charlottesville, Chicago, Cincinnati, Denver, Durham, Houston, Indianapolis, Iowa City, Jackson, Jacksonville, Los Angeles, Memphis, Miami, Minneapolis, New York, Philadelphia, Phoenix, Rochester, Salt Lake City, San Antonio, San Diego, Seattle, The Bronx, Winston-Salem
Age
18 years and over
People
8,000
Run by
Massachusetts General Hospital
See details and how to joinNCT04916210
No phaseTaking people
Study to Understand Novel Biomarkers in Researching Dementia
Where
St Louis
Age
60 years and over
People
1,800
Run by
Washington University School of Medicine
See details and how to joinNCT06547099
No phaseTaking people
Accelerated Age-related Cognitive Decline: Impact of Exercise on Executive Function and Neuroplasticity
Where
New York, Washington D.C.
Age
55 years and over
People
144
Run by
Columbia University
See details and how to joinNCT05655325
No phaseTaking people
Evaluating Novel Healthcare Approaches to Nurturing and Caring for Hospitalized Elders
Where
Ann Arbor, Madison, Orange, Philadelphia, Pittsburgh, Portland, Salt Lake City
Age
70 years and over
People
1,900
Run by
University of Michigan
See details and how to joinNCT05929703