Mild cognitive impairment trials in United States

In United States 203 Also abroad 457

203 trials · From ClinicalTrials.gov, checked 15 November 2026. Ask the study team whether a trial fits you.

Phase 1/2Taking people
Snacks and Brain Health
Where
Lubbock
Age
50 years and over
People
60
Run by
Texas Tech University Health Sciences Center
See details and how to joinNCT07348406
Early phase 1Taking people
Psilocybin for Depression in People With Mild Cognitive Impairment or Early Alzheimer's Disease
Where
Baltimore
Age
18 years to 85 years
People
20
Run by
Johns Hopkins University
See details and how to joinNCT04123314
No phaseTaking people
OTC Hearing Aid and MCI
Where
Evanston, La Crosse, Madison
Age
60 years to 90 years
People
50
Run by
Northwestern University
See details and how to joinNCT06112860
No phaseTaking people
Olfactory Training in Mild Cognitive Impairment
Where
New York
Age
55 years to 89 years
People
30
Run by
Jeffrey Motter
See details and how to joinNCT06825403
No phaseTaking people
ADRC Clinical Cohort (Alzheimer's Disease)
Where
Durham
Age
25 years to 80 years
People
500
Run by
Duke University
See details and how to joinNCT06703541
No phaseTaking people
Closed-Loop Brain Stimulation as a Potential Intervention for Cognitive Decline
Where
Austin
Age
18 years to 90 years
People
180
Run by
University of Texas at Austin
See details and how to joinNCT05907343
No phaseTaking people
Feasibility, Usability, and Acceptability of Virtual Reality-Based Cognitive and Physical Rehabilitation in Individuals With Mild Cognitive Impairment
Where
Houston
Age
55 years to 90 years
People
10
Run by
The University of Texas Health Science Center, Houston
See details and how to joinNCT07638748
No phaseNot yet taking people in United States
Wearable Sensor for Early Detection and Monitoring of Cognitive Decline
Where
Los Angeles
Age
55 years and over
People
100
Run by
BioSensics
See details and how to joinNCT07780162
No phaseTaking people
Contributions of mTBI to Neurodegeneration Due to Chronic Traumatic Encephalopathy (CTE) and Alzheimer's Disease (AD)
Where
Boston
Age
30 years to 90 years
People
800
Run by
VA Office of Research and Development
See details and how to joinNCT04124029
Early phase 1Taking people
LpD3.5 Intervention Study in Older Adults- LISA-I Trial
Where
Tampa
Age
60 years and over
People
15
Run by
University of South Florida
See details and how to joinNCT07794956
No phaseNot yet taking people in United States
AI-CONECT: A Conversational AI for Early Dementia Prevention in Socially-Isolated Older Adults
Where
Boston
Age
75 years and over
People
80
Run by
Massachusetts General Hospital
See details and how to joinNCT07701668
No phaseNot yet taking people in United States
Mindfulness-Based Cognitive Therapy Vs. the Health Enhancement Program for Chronic Pain and Early Cognitive Decline; The Feeling of Being Pilot RCT
Where
Boston
Age
50 years to 120 years
People
60
Run by
Massachusetts General Hospital
See details and how to joinNCT07785648
No phaseTaking people
A Primary Care-Based Psychosocial Intervention To Improve Cognitive & Depression Outcomes in Older Adults With MCI & Early Stage AD
Where
White Plains
Age
60 years and over
People
100
Run by
Weill Medical College of Cornell University
See details and how to joinNCT05081596
No phaseNot yet taking people in United States
Center for Research and Education on Aging and Technology Enhancement - CREATE V - Project 1
Where
Champaign, New York, Tallahassee
Age
60 years and over
People
108
Run by
Weill Medical College of Cornell University
See details and how to joinNCT05811338
Phase 2Taking people
Senicapoc in Alzheimer's Disease
Where
Sacramento, Walnut Creek
Age
55 years to 85 years
People
55
Run by
University of California, Davis
See details and how to joinNCT04804241
No phaseNot yet taking people in United States
Center for Research and Education on Aging and Technology Enhancement - CREATE V - Project 2
Where
Champaign, New York, Tallahassee
Age
60 years and over
People
120
Run by
Weill Medical College of Cornell University
See details and how to joinNCT07485712
No phaseEnrolling by invitation
Wisconsin Brain Donor Program
Where
Madison
Age
18 years and over
People
9,999
Run by
University of Wisconsin, Madison
See details and how to joinNCT00585572
No phaseTaking people
Use of a Mobile Brain-Body Imaging Approach to Evaluate the Effects of Rhythmic Auditory Stimulation on Gait and Brain Function in Alzheimer's Disease
Where
Boston
Age
50 years to 90 years
People
40
Run by
Boston University Charles River Campus
See details and how to joinNCT07659964
Phase 2Taking people
The Mito-Frail Trial: Effects of MitoQ on Vasodilation, Mobility and Cognitive Performance in Frail Older Adults
Where
Farmington
Age
65 years to 80 years
People
60
Run by
UConn Health
See details and how to joinNCT06027554
No phaseTaking people
Neuromodulation of Memory in Aging
Where
Durham
Age
18 years to 75 years
People
150
Run by
Indiana University
See details and how to joinNCT05460468
Phase 2Enrolling by invitation
Alzheimer's Disease Research Center (ADRC) PET Component Study
Where
New York
Age
50 years and over
People
120
Run by
Patrick Lao
See details and how to joinNCT07758660
Phase 1Taking people
Safety And Tolerability Of Gamma Glutamylcysteine (GGC) Oral Supplementation In MCI Patients
Where
Pittsburgh
Age
55 years to 80 years
People
9
Run by
Pravat Mandal
See details and how to joinNCT07583251
No phaseEnrolling by invitation
Assessing and Improving the Durability of Compensatory Cognitive Training for Older Veterans
Where
San Diego
Age
55 years and over
People
28
Run by
VA Office of Research and Development
See details and how to joinNCT05770479
No phaseTaking people
Autoimmune Features of Neurodegenerative Disorders
Where
New York
Age
55 years to 90 years
People
120
Run by
Columbia University
See details and how to joinNCT04239079
No phaseNot yet taking people in United States
Sleep Interventions and Neurocognitive Outcomes
Where
New York
Age
60 years to 85 years
People
50
Run by
New York State Psychiatric Institute
See details and how to joinNCT05987007