Mild cognitive impairment trials in United States

In United States 203 Also abroad 457

203 trials · From ClinicalTrials.gov, checked 15 November 2026. Ask the study team whether a trial fits you.

No phaseTaking people
Effects of Transcranial Focused Ultrasound Stimulation (tFUS) on Neurological and Cognitive Outcomes in Parkinson's Disease
Where
Gainesville, New York, Santa Monica, Tucson
Age
22 years to 80 years
People
60
Run by
Sanmai Technologies PBC dba Sanmai
See details and how to joinNCT07207122
Phase 4Enrolling by invitation
MIBG in Aging and Neurologic Disorders
Where
Rochester
Age
40 years to 90 years
People
50
Run by
Mayo Clinic
See details and how to joinNCT05514106
Phase 2Taking people
Cognitive Training and Neuroplasticity in Mild Cognitive Impairment: COGIT-2 Trial
Where
Durham, Miami, New York, Seattle
Age
55 years to 89 years
People
240
Run by
Columbia University
See details and how to joinNCT06601933
No phaseTaking people
Enhancing Attention in Elderly Using a Brain-Computer-Interface
Where
Austin, Georgetown
Age
18 years to 90 years
People
100
Run by
University of Texas at Austin
See details and how to joinNCT07441122
No phaseTaking people
Improve New Learning and Memory in Individuals With Mild Cognitive Impairment
Where
Ann Arbor, West Orange
Age
60 years and over
People
120
Run by
Kessler Foundation
See details and how to joinNCT05396248
Phase 2Taking people
Pathways Relating Amnestic MCI to a Mild Traumatic Brain Injury History
Where
Dallas
Age
55 years and over
People
75
Run by
University of Texas Southwestern Medical Center
See details and how to joinNCT05446584
No phaseTaking people
Molecular and Structural Imaging in Alzheimer's Disease: A Longitudinal Study
Where
Rochester
Age
21 years to 80 years
People
60
Run by
Mayo Clinic
See details and how to joinNCT02740634
No phaseTaking people
Goal Setting to Promote Physical Activity Adherence in Midlife Adults
Where
Phoenix
Age
45 years to 65 years
People
144
Run by
Arizona State University
See details and how to joinNCT05980052
No phaseTaking people
A Feasiblity Study of Green Activity Program for People Living With Memory Challenges
Where
Bloomington
Age
45 years and over
People
40
Run by
Indiana University
See details and how to joinNCT06403345
No phaseTaking people
Individual Closed-Loop Neuromodulation Therapy for Alzheimer's Disease
Where
Charlestown
Age
50 years to 80 years
People
70
Run by
Massachusetts General Hospital
See details and how to joinNCT05904132
Phase 2Taking people
Trial of CORT108297 to Attenuate the Effects of Acute Stress in the Allocortex (CORT-X)
Where
Baltimore
Age
55 years and over
People
52
Run by
Johns Hopkins University
See details and how to joinNCT04601038
Phase 2Taking people
Evaluate the Effect of Atorvastatin on Cerebrovascular Reactivity in Mild Cognitive Impairment (MCI)
Where
Baltimore
Age
60 years to 95 years
People
20
Run by
Johns Hopkins University
See details and how to joinNCT04765137
No phaseEnrolling by invitation
Georgia Memory Net Anti-Amyloid Monoclonal Antibody Registry
Where
Albany, Atlanta, Augusta, Gainesville, Macon, Savannah, Vidalia
Age
50 years to 90 years
People
735
Run by
Emory University
See details and how to joinNCT05999084
No phaseTaking people
Dual Task Perturbation Training for OAwMCI
Where
Chicago
Age
55 years and over
People
142
Run by
University of Illinois Chicago
See details and how to joinNCT04938349
No phaseTaking people
Digital Tools to Support Healthcare Decision Making
Where
Champaign, New York, Tallahassee
Age
60 years and over
People
120
Run by
Weill Medical College of Cornell University
See details and how to joinNCT07485725
No phaseTaking people
Healthy Aging as Black Adults, In It Together: a Comparative Effectiveness Study of Chronic Pain and Cognitive Decline
Where
Boston
Age
50 years and over
People
400
Run by
Massachusetts General Hospital
See details and how to joinNCT06246929
No phaseTaking people
Voice Technology-Based Self-Management Intervention
Where
Atlanta
Age
55 years and over
People
20
Run by
Emory University
See details and how to joinNCT06982261
Phase 2Taking people
Longitudinal Imaging of Microglial Activation in Different Clinical Variants of Alzheimer's Disease
Where
New York
Age
50 years and over
People
100
Run by
Columbia University
See details and how to joinNCT04576793
No phaseTaking people
Feasibility of Implementing Time-restricted Eating in Women With Mild Cognitive Impairment
Where
Lexington
Age
45 years to 95 years
People
15
Run by
Julie Pendergast
See details and how to joinNCT05858008
Phase 4Enrolling by invitation
Imaging of Brain Amyloid Plaques in the Aging Population
Where
Rochester
Age
30 years to 100 years
People
8,000
Run by
Mayo Clinic
See details and how to joinNCT00950430
Phase 2Taking people
Targeting Cognition in Early Alzheimer's Disease by Improving Sleep With Trazodone
Where
Baltimore
Age
55 years and over
People
100
Run by
Johns Hopkins University
See details and how to joinNCT05282550
No phaseTaking people
e-ALIGN: A Patient Portal-based Intervention to Align Medications With What Matters Most
Where
Baltimore
Age
65 years and over
People
100
Run by
Johns Hopkins University
See details and how to joinNCT07454824
No phaseTaking people
Using Light Therapy for Mild Cognitive Impairment
Where
Oklahoma City
Age
55 years to 95 years
People
40
Run by
University of Oklahoma
See details and how to joinNCT07651787
Phase 2Taking people
CBD for Individuals at Risk for Alzheimer's Disease
Where
Aurora
Age
55 years to 85 years
People
236
Run by
University of Colorado, Denver
See details and how to joinNCT05822362
No phaseEnrolling by invitation
Integrating eSAGE With EHR Data Using Machine Learning for the Early Detection and Monitoring of Cognitive Impairment in Individuals
Where
Columbus
Age
50 years and over
People
1,486
Run by
Douglas Scharre
See details and how to joinNCT06017505