Mild cognitive impairment trials in United States

In United States 203 Also abroad 457

203 trials · From ClinicalTrials.gov, checked 15 November 2026. Ask the study team whether a trial fits you.

No phaseTaking people
Development of a Database to Investigate Digital and Blood-Based Biomarkers and Their Relationship to Tau and Amyloid PET Imaging in Older Participants Who Are Cognitively Normal (CN), Have Mild Cognitive Impairment (MCI), or Have Mild-to-Moderate AD Dementia
Where
Albany, Atlantis, Aventura, Beaumont, Chicago, Clermont, Delray Beach, East Providence, Farmington Hills, Fort Myers, Houston, Las Vegas, Maitland, Melbourne, Miami, North Canton, Orlando, Philadelphia, Port Orange, Sarasota, Tampa, Winter Park
Age
60 years to 90 years
People
1,200 worldwide
Run by
GAP Innovations, PBC
See details and how to joinNCT06584357
Phase 2Taking people
Ultralow Dose PET Imaging of 18F-Florbetapir, 18F-Flutemetamol
Where
Englewood
Age
18 years to 120 years
People
200
Run by
Akiva Mintz
See details and how to joinNCT07012993
No phaseNot yet taking people in United States
Fall Prevention in Mild Cognitive Impairment
Where
Baltimore
Age
65 years and over
People
28
Run by
VA Office of Research and Development
See details and how to joinNCT07507812
No phaseEnrolling by invitation
Impact of Yoga on Cognitive Function
Where
Auburn
Age
55 years to 70 years
People
24
Run by
Auburn University
See details and how to joinNCT06434168
No phaseEnrolling by invitation
The Digital Memory Notebook
Where
Sacramento
Age
60 years and over
People
20
Run by
University of California, Davis
See details and how to joinNCT04240665
No phaseTaking people
Transcranial Magnetic Stimulation for MCI
Where
Charleston
Age
60 years to 85 years
People
60
Run by
Medical University of South Carolina
See details and how to joinNCT05992831
No phaseTaking people
BID LTM Digital Intervention in Aging
Where
San Francisco
Age
60 years to 85 years
People
150
Run by
University of California, San Francisco
See details and how to joinNCT06916221
No phaseTaking people
BID WM Digital Intervention in Aging
Where
San Francisco
Age
60 years to 85 years
People
150
Run by
University of California, San Francisco
See details and how to joinNCT06918704
Phase 2Taking people
Reducing Falls With Varenicline in Hypocholinergic Parkinson Disease
Where
Ann Arbor
Age
45 years and over
People
102
Run by
Vikas Kotagal
See details and how to joinNCT06679374
No phaseEnrolling by invitation
The Comparative Effectiveness Dementia & Alzheimer's Registry
Where
New York
Age
18 years to 99 years
People
452
Run by
Weill Medical College of Cornell University
See details and how to joinNCT03687710
No phaseTaking people
Early-Stage Partner in Care Living Alone Plus
Where
Phoenix
Age
60 years and over
People
70
Run by
Arizona State University
See details and how to joinNCT06962111
No phaseEnrolling by invitation
AI-Supported Cognitive Rehabilitation for Older Adults With Mild Cognitive Impairment
Where
Pasadena
Age
65 years and over
People
130
Run by
Kaiser Permanente
See details and how to joinNCT07474038
Phase 1/2Taking people
Sense4Safety Intervention
Where
Philadelphia
Age
65 years and over
People
200
Run by
University of Pennsylvania
See details and how to joinNCT07220668
Phase 4Enrolling by invitation
DaTSCAN Imaging in Aging and Neurodegenerative Disease
Where
Rochester
Age
40 years to 90 years
People
500
Run by
Mayo Clinic
See details and how to joinNCT01453127
No phaseTaking people
Multimodal Investigation of Neural Plasticity
Where
Ann Arbor
Age
60 years and over
People
80
Run by
University of Michigan
See details and how to joinNCT06453980
Early phase 1Not yet taking people in United States
Mild Cognitive Impairment Community Screening and Early Intervention Via Stem Cell Therapy and Wearable Brain Computer Interface Device.
Where
Palisades Park
Age
55 years and over
People
600
Run by
Noah Tech, Corp.
See details and how to joinNCT07214974
No phaseTaking people
Digital Accessible Remote Olfactory Mediated Health Assessments for Preclinical AD
Where
Boston
Age
18 years to 100 years
People
250
Run by
Massachusetts General Hospital
See details and how to joinNCT05881239
Phase 4Taking people
Elucidating the Role of Cholinergic Degeneration in Cognitive Fluctuations in Lewy Body Dementia
Where
Richmond
Age
50 years to 89 years
People
120
Run by
Virginia Commonwealth University
See details and how to joinNCT07284290
No phaseTaking people
Anxiety Sensitivity Treatment to Reduce Anxiety in Alzheimer's
Where
Athens, Columbus, Tallahassee
Age
60 years and over
People
388
Run by
Florida State University
See details and how to joinNCT05748613
No phaseTaking people
Locomotion Adaptation Deficits in Older Adults With Mild Cognitive Impairment and Alzheimers Disease
Where
Atlanta
Age
50 years to 90 years
People
10
Run by
Emory University
See details and how to joinNCT06484244
No phaseTaking people
Study to Investigate Vagus Nerve Stimulation to Augment Executive Function in Healthy and Cognitively Impaired Populations
Where
Aurora
Age
18 years to 65 years
People
80
Run by
University of Colorado, Denver
See details and how to joinNCT07424365
Phase 2Taking people
Assessment of Foralumab Safety and Modulation of Microglial Activation in Alzheimer's Disease
Where
Boston
Age
60 years to 85 years
People
16
Run by
Brigham and Women's Hospital
See details and how to joinNCT06489548
No phaseTaking people
Cancer and Mild Cognitive Impairment Dyadic Intervention
Where
Durham
Age
18 years to 100 years
People
80
Run by
Duke University
See details and how to joinNCT05144516
Phase 2Taking people
ALA-enriched Nutrition for Prevention of Cognitive Decline in APOE4 Older Adults
Where
New Brunswick
Age
60 years and over
People
20
Run by
Michal Schnaider Beeri, Ph.D.
See details and how to joinNCT07392723
No phaseTaking people
Cognitive Screening Made Easy for PCPs - Administrative Supplement
Where
Austin, San Antonio
Age
60 years and over
People
100
Run by
University of Texas at Austin
See details and how to joinNCT06928298