Mild cognitive impairment trials in United States

In United States 203 Also abroad 457

203 trials · From ClinicalTrials.gov, checked 15 November 2026. Ask the study team whether a trial fits you.

No phaseTaking people
Retinal Imaging in Neurodegenerative Disease
Where
Durham
Age
18 years and over
People
2,000
Run by
Duke University
See details and how to joinNCT03233646
No phaseTaking people
Cognitive Vulnerability to Stress in Individuals at Risk for Alzheimer's Disease
Where
Baltimore
Age
60 years and over
People
240
Run by
Johns Hopkins University
See details and how to joinNCT05795634
No phaseTaking people
Effects of Sabroxy® Supplementation on Insulin Resistance and Cognitive Function in Adults With Mild Cognitive Impairment and Insulin Resistance
Where
San Francisco
Age
40 years to 80 years
People
140
Run by
SF Research Institute, Inc.
See details and how to joinNCT07220694
Phase 1/2Not yet taking people in United States
Epileptic Hippocampus in Alzheimer's Disease
Where
Los Angeles
Age
45 years to 70 years
People
25
Run by
University of California, Los Angeles
See details and how to joinNCT05899764
Phase 3Taking people
Biomarker Exploration in Aging, Cognition and Neurodegeneration
Where
Irvine
Age
60 years and over
People
300
Run by
University of California, Irvine
See details and how to joinNCT03860857
No phaseTaking people
Home Based Functional Balance Intervention for Multiple Sclerosis
Where
Chicago
Age
40 years to 90 years
People
75
Run by
University of Illinois Chicago
See details and how to joinNCT07355387
No phaseEnrolling by invitation
MR Elastography of Cognitive Impairment
Where
Rochester
Age
18 years to 100 years
People
450
Run by
Mayo Clinic
See details and how to joinNCT06029114
Phase 1Taking people
Innate Immunity Stimulation Via TLR9 in Early AD
Where
New York
Age
60 years to 85 years
People
18
Run by
NYU Langone Health
See details and how to joinNCT05606341
No phaseEnrolling by invitation
Biodistribution of [11C]PIB in Patients With Risk Factors for Alzheimer's Disease
Where
Winston-Salem
Age
55 years and over
People
800
Run by
Wake Forest University Health Sciences
See details and how to joinNCT03089827
No phaseTaking people
GAMES Intervention in MCI (Mild Cognitive Impairment)
Where
Atlanta
Age
50 years to 85 years
People
124
Run by
Emory University
See details and how to joinNCT07296133
No phaseTaking people
A Study of Dual-task Exercise Training to Prevent Falls Among Older Adults With Mild Cognitive Impairment
Where
Springfield
Age
65 years to 95 years
People
336
Run by
Oregon Research Institute
See details and how to joinNCT05725668
No phaseTaking people
The Active Mind Trial: An Adaptive Randomized Trial to Improve Function and Delay Dementia
Where
Gainesville, Greenville, Minneapolis, San Francisco, Seneca, Tampa
Age
55 years to 89 years
People
1,305
Run by
University of Alabama at Birmingham
See details and how to joinNCT04171323
No phaseEnrolling by invitation
Can (Optical Coherence Tomography) Pictures of the Retina Detect Alzheimer's Disease at Its Earliest Stages?
Where
Sacramento
Age
50 years to 89 years
People
100
Run by
University of California, Davis
See details and how to joinNCT06023446
No phaseTaking people
Low-Intensity Focused Ultrasound (LIFU) Neuromodulation
Where
Morgantown
Age
45 years to 85 years
People
15
Run by
Ali Rezai
See details and how to joinNCT05997030
Phase 1Enrolling by invitation
tFUS for Memory in mNCD and Healthy Adults
Where
Charleston
Age
50 years to 85 years
People
25
Run by
Medical University of South Carolina
See details and how to joinNCT06718140
No phaseTaking people
Passive Sensor Identification of Digital Biomarkers to Assess Effects of Orally Administered Nicotinamide Riboside
Where
Belmont
Age
18 years to 89 years
People
40
Run by
Mclean Hospital
See details and how to joinNCT05245903
No phaseTaking people
Memory Support System for Older Chinese Americans With Mild Cognitive Impairment
Where
New York
Age
55 years and over
People
7
Run by
Icahn School of Medicine at Mount Sinai
See details and how to joinNCT07142499
No phaseTaking people
TabCAT Brain Health Assessment in Primary Care
Where
Pasadena
Age
18 years and over
People
180,000
Run by
University of California, San Francisco
See details and how to joinNCT06090578
No phaseTaking people
bpMedManage: Digital Technology to Support Adherence to Hypertension Medications
Where
Champaign, Tucson
Age
60 years and over
People
100
Run by
University of Arizona
See details and how to joinNCT06307574
No phaseTaking people
OCT Angiography and NRAI in Dementia
Where
Portland
Age
55 years and over
People
20
Run by
Oregon Health and Science University
See details and how to joinNCT03761381
Phase 4Enrolling by invitation
Quality Improvement and Practice Based Research in Neurology Using the EMR
Where
Evanston
Age
18 years to 100 years
People
3,300
Run by
Endeavor Health
See details and how to joinNCT02670161
No phaseTaking people
Remote Sensing for ADRD-Specific Activities Identification in Older Adults
Where
Columbia
Age
50 years and over
People
16
Run by
University of Missouri-Columbia
See details and how to joinNCT07120347
No phaseEnrolling by invitation
Application of the Modified Story Memory Technique (mSMT)© to Aging
Where
East Hanover
Age
65 years and over
People
33
Run by
Kessler Foundation
See details and how to joinNCT03370224
Phase 3Taking people
Visualizing Brain Proteinopathies Using [F-18]Flornaptitril-PET in the Prediction of Clinical Progression of Mild Cognitive Impairment With Either Suspected Chronic Traumatic Encephalopathy or Alzheimer's Disease
Where
Evanston
Age
45 years and over
People
230
Run by
CereMark Pharma, LLC
See details and how to joinNCT06254469
No phaseTaking people
Race-Based Stress and Cognitive Training for MCI
Where
Chicago
Age
65 years and over
People
9
Run by
Rosalind Franklin University of Medicine and Science
See details and how to joinNCT06330844