Multiple myeloma trials in United States

In United States 297 Also abroad 703

297 trials · From ClinicalTrials.gov, checked 11 November 2026. Ask the study team whether a trial fits you.

Phase 2Taking people
A Study to Evaluate Efficacy and Safety of Ciltacabtagene Autoleucel
Where
Charlotte, Cleveland, Iowa City, New York, San Francisco, Tampa, Winston-Salem
Age
18 years to 80 years
People
60 worldwide
Run by
Janssen Research & Development, LLC
See details and how to joinNCT07149857 · EU 2025-521975-30-00
Phase 3Taking people
A Study Comparing JNJ-79635322 and an Anti-B-cell Maturation Antigen (BCMA)xCD3 Bispecific Antibody in Participants With Relapsed or Refractory Multiple Myeloma
Where
Ann Arbor, Atlanta, Austin, Baltimore, Boston, Brooklyn, Chapel Hill, Cleveland, Dallas, Denver, Duarte, Durham, Farmington, Fort Myers, Houston, Iowa City, Irvine, Jacksonville, Kansas City, Little Rock, Los Angeles, Louisville, Miami, Milwaukee, Mineola, Nashville, New Haven, New York, Philadelphia, Phoenix, Portland, Rochester, Salt Lake City, San Antonio, San Francisco, Tampa, Waukee, Zion
Age
18 years and over
People
400 worldwide
Run by
Janssen Research & Development, LLC
See details and how to joinNCT07258511 · EU 2025-522007-18-00
Phase 2Taking people
A Study Evaluating the Prophylactic Use of Tocilizumab to Prevent Cytokine Release Syndrome With Ramantamig Administration in Participants With Relapsed/Refractory Multiple Myeloma
Where
Beverly Hills, Columbus, Denver, Goodyear, Irvine, Nashville, Palo Alto, Salt Lake City, St Louis
Age
18 years and over
People
230 worldwide
Run by
Janssen Research & Development, LLC
See details and how to joinNCT07589634
No phaseTaking people
Family Study of Lymphoproliferative Disorders
Where
Rochester
Age
18 years to 100 years
People
3,000
Run by
Mayo Clinic
See details and how to joinNCT00626496
Phase 2Taking people
Personalized NK Cell Therapy in CBT
Where
Houston
Age
15 years to 80 years
People
100
Run by
M.D. Anderson Cancer Center
See details and how to joinNCT02727803
Phase 2Taking people
Minimal Residual Disease Guided Maintenance Therapy With Belantamab Mafodotin and Lenalidomide After Autologous Hematopoietic Cell Transplantation in Patients With Newly Diagnosed Multiple Myeloma
Where
Houston
Age
18 years and over
People
94
Run by
M.D. Anderson Cancer Center
See details and how to joinNCT05091372
Phase 1Taking people
ELEVATE-MM: Elotuzumab, Iberdomide and Dexamethasone Post Idecabtagene Vicleucel in Relapsed and Refractory Multiple Myeloma
Where
Boston
Age
18 years and over
People
24
Run by
Omar Nadeem, MD
See details and how to joinNCT06518551
Phase 1Taking people
Autologous T Cells Transduced With Retroviral Vectors Expressing TCRs for Participant-specific Neoantigens in Patients With Hematologic Malignancies
Where
Bethesda
Age
18 years to 120 years
People
86
Run by
National Cancer Institute (NCI)
See details and how to joinNCT06904066
Phase 1/2Taking people
A Study of Dara-RVd and Teclistamab-RVd in People With Multiple Myeloma
Where
Basking Ridge, Commack, Harrison, Middletown, Montvale, New York, Uniondale
Age
18 years and over
People
65
Run by
Memorial Sloan Kettering Cancer Center
See details and how to joinNCT07099391
Phase 1Taking people
Systemic Anti-Cancer Therapy Dose Modifications for Individuals With Duffy Null Phenotype
Where
Boston, Cincinnati
Age
18 years and over
People
90
Run by
Andrew Hantel, MD
See details and how to joinNCT07341867
No phaseNot yet taking people in United States
Monitoring for CardioToxicity Using WeArable deVices While Undergoing cancEr Treatments (MCT-WAVE)
Where
Minneapolis
Age
18 years and over
People
72
Run by
University of Minnesota
See details and how to joinNCT07776964
Phase 2Taking people
Administration of Autologous T-Cells Genetically Engineered to Express T-Cell Receptors Reactive Against Neoantigens in People With Metastatic Cancer
Where
Bethesda
Age
18 years to 72 years
People
285
Run by
National Cancer Institute (NCI)
See details and how to joinNCT03412877
Phase 1Taking people
Radioimmunotherapy (111Indium/225Actinium-DOTA-daratumumab) for the Treatment of Relapsed/Refractory Multiple Myeloma
Where
Duarte
Age
18 years and over
People
15
Run by
City of Hope Medical Center
See details and how to joinNCT05363111
Phase 3Taking people
A Study to Evaluate Mezigdomide, Bortezomib and Dexamethasone (MEZIVd) Versus Pomalidomide, Bortezomib and Dexamethasone (PVd) in Participants With Relapsed or Refractory Multiple Myeloma (RRMM)
Where
Abilene, Albuquerque, Allentown, Ann Arbor, Athens, Aurora, Baltimore, Baton Rouge, Boston, Buffalo, Cincinnati, Cleveland, Coral Springs, Detroit, Durham, East Brunswick, Farmington, Fort Myers, Fredericksburg, Garden City, Germantown, Hattiesburg, Houston, Jackson, Lake Success, Los Alamitos, Madison, Marietta, Mayfield Heights, Minneapolis, New Haven, New Hyde Park, New Orleans, New York, Norfolk, Orange City, Ridgewood, Roanoke, Rochester, Salt Lake City, San Antonio, San Diego, Seattle, Shirley, Shreveport, Spokane, The Bronx, Vancouver, West Hollywood, West Palm Beach, Westwood, Williamsville, York
Age
18 years and over
People
810 worldwide
Run by
Celgene
See details and how to joinNCT05519085
No phaseTaking people
Real World Treatment Experience of Patients With Breast, Lung, Ovarian, Multiple Myeloma, or Acute Myelogenous Leukemia Using Remote Symptom Monitoring
Where
Canton, Chapel Hill, Cleveland, Durham, Evanston, Massillon, New Haven
Age
18 years and over
People
25
Run by
Carevive Systems, Inc.
See details and how to joinNCT05974150
Phase 1/2Taking people
AZD0305 as Monotherapy or in Combination With Anticancer Agents in Participants With Multiple Myeloma
Where
Ann Arbor, Atlanta, Boston, Duarte, Fairfax, Irvine, New York, Philadelphia, St Louis
Age
18 years and over
People
226 worldwide
Run by
AstraZeneca
See details and how to joinNCT06106945 · EU 2023-508590-89-00
Phase 1Taking people
Study to Assess Safety and Tolerability of OPN-6602 in Subjects With Relapsed and/or Refractory Multiple Myeloma
Where
Atlanta, Boston, Chapel Hill, Detroit, Gilbert, Grand Rapids, La Jolla, Rochester, Salt Lake City, Seattle, Stanford, Westwood
Age
18 years and over
People
130
Run by
Opna Bio LLC
See details and how to joinNCT06433947
No phaseTaking people
Mosaic Trial for Stem Cell Transplant Recipients
Where
Chicago, Nutley, Washington D.C.
Age
18 years and over
People
356
Run by
Northwestern University
See details and how to joinNCT06960993
Phase 1Taking people
A Study to Learn About the Effects of Cemsidomide in Combination With Elranatamab in Relapsed/Refractory Multiple Myeloma Subjects
Where
Atlanta, Baltimore, Brooklyn, Columbus, Dallas, Durham, Gilbert, Grand Rapids, Houston, Indianapolis, Lebanon, Louisville, Maywood, Miami, New York, Omaha, Sacramento, Salt Lake City, Santa Monica
Age
18 years and over
People
60
Run by
C4 Therapeutics, Inc.
See details and how to joinNCT07280013
Phase 2Taking people
A Study to Evaluate the Efficacy of Cemsidomide + Dexamethasone in Participants With Relapsed/Refractory Multiple Myeloma
Where
Ann Arbor, Atlanta, Boston, Chapel Hill, Detroit, Duarte, Grand Rapids, Huntsville, Indianapolis, Iowa City, Jacksonville, Madison, Milwaukee, Nashville, New York, Omaha, Phoenix, Rochester, San Antonio, Scottsdale, St Louis, West Hollywood
Age
18 years and over
People
100 worldwide
Run by
C4 Therapeutics, Inc.
See details and how to joinNCT07284758 · EU 2025-524181-26-00
No phaseTaking people
Cancer Experience Registry (CER) for Cancer Patients and Caregivers
Where
Washington D.C.
Age
18 years and over
People
15,000
Run by
Cancer Support Community, Research and Training Institute, Philadelphia
See details and how to joinNCT02333604
No phaseTaking people
The Indiana Myeloma Registry
Where
Indianapolis
Age
18 years and over
People
2,500
Run by
Indiana University
See details and how to joinNCT03616483
Phase 3Taking people
A Study to Compare the Efficacy and Safety of BMS-986393 Versus Standard Regimens in Adult Participants With Relapsed or Refractory and Lenalidomide-exposed Multiple Myeloma (QUINTESSENTIAL-2)
Where
Atlanta, Birmingham, Boston, Charleston, Charlotte, Cleveland, Houston, Jacksonville, Los Angeles, Miami, Milwaukee, Minneapolis, New York, Orange, Orlando, Philadelphia, Pittsburgh, Salt Lake City, Shreveport, Stony Brook, Washington D.C.
Age
18 years and over
People
440 worldwide
Run by
Juno Therapeutics, Inc., a Bristol-Myers Squibb Company
See details and how to joinNCT06615479 · EU 2024-515279-37-00
No phaseTaking people
Tissue, Blood, and Body Fluid Sample Collection From Patients With Hematologic Cancer
Where
Chapel Hill
Age
18 years to 120 years
People
15,000
Run by
UNC Lineberger Comprehensive Cancer Center
See details and how to joinNCT01137643
No phaseTaking people
HEME Home Transfusion Program
Where
Boston
Age
18 years and over
People
700
Run by
Dana-Farber Cancer Institute
See details and how to joinNCT06487247