Multiple myeloma trials in United States

In United States 297 Also abroad 703

297 trials · From ClinicalTrials.gov, checked 12 November 2026. Ask the study team whether a trial fits you.

Phase 3Taking people
Lenalidomide, and Dexamethasone With or Without Daratumumab in Treating Patients With High-Risk Smoldering Myeloma
Where
Aberdeen, Adrian, Aitkin, Albany, Albert Lea, Allentown, Alma, Alton, American Fork, Ames, Anaconda, Anchorage, Ankeny, Ann Arbor, Appleton, Arroyo Grande, Ashland, Atlanta, Auburn, Aurora, Baker City, Ballwin, Baltimore, Bardstown, Barrington, Baton Rouge, Battle Creek, Baytown, Beavercreek, Bellevue, Bellingham, Belpre, Bend, Bethlehem, Bettendorf, Billings, Birmingham, Bloomington, Boardman, Boiling Springs, Boise, Bolivar, Boone, Boston, Boulder, Bozeman, Brainerd, Branson, Bridgeport, Brighton, Brownstown, Bryan, Burbank, Burien, Burlington, Burnsville, Burr Ridge, Butte, Caldwell, Cambridge, Camden, Camillus, Canton, Cape Girardeau, Carbondale, Carmel, Carmichael, Caro, Carroll, Carson City, Carterville, Carthage, Cedar City, Centennial, Centerville, Centralia, Chapel Hill, Chardon, Charleston, Charlotte, Charlottesville, Chaska, Chelsea, Chesterfield, Cheyenne, Chicago, Chillicothe, Cincinnati, City of Saint Peters, Clackamas, Clarkston, Cleveland, Clinton Township, Clive, Cody, Coeur d'Alene, Colorado Springs, Columbus, Conroe, Coon Rapids, Coos Bay, Corbin, Council Bluffs, Creston, Creve Coeur, Crystal Lake, Cudahy, Dallas, Danville, Dayton, Dearborn, Decatur, Deer River, DeKalb, Delaware, Denver, Derby, Des Moines, Detroit, Detroit Lakes, Dixon, Downers Grove, Dublin, Duluth, Durango, Easley, East China Township, East Stroudsburg, East Syracuse, Eau Claire, Edina, Edmonds, Effingham, Elgin, Elk Grove, Emeryville, Emmett, Englewood, Enumclaw, Eureka, Evanston, Everett, Fairbanks, Fairfield, Fargo, Farmington, Federal Way, Fergus Falls, Findlay, Flint, Fond du Lac, Fort Dodge, Fort Lauderdale, Fort Smith, Fort Worth, Fosston, Franklin, Fridley, Fruitland, Gahanna, Galesburg, Garden City, Geneva, Germantown, Gig Harbor, Glastonbury, Glens Falls, Glenview, Golden, Goodyear, Grafton, Grand Island, Grand Junction, Grand Rapids, Great Bend, Great Falls, Greeley, Green Bay, Greenville, Greenwich, Greenwood, Greer, Grosse Pointe Woods, Grove City, Guilford, Hartford, Harvey, Havre, Hayward, Hazel Crest, Hazleton, Henderson, Hershey, Hibbing, Highland Park, Hillsborough, Homer Glen, Hot Springs, Houston, Indianapolis, Iowa City, Issaquah, Jackson, Jamestown, Janesville, Jefferson, Jefferson City, Johns Creek, Johnson Creek, Joliet, Joplin, Kalamazoo, Kalispell, Kansas City, Kearney, Kenansville, Kennewick, Kenosha, Kettering, Kewanee, Kingman, Kinston, Kirkland, Lacey, La Crosse, Lafayette, La Jolla, Lakewood, Lancaster, Lansing, Las Vegas, League City, Lee's Summit, Lewisburg, Lewistown, Lexington, Libertyville, Lima, Lincoln, Littleton, Livonia, Logan, London, Lone Tree, Longmont, Longview, Louisville, Loveland, Macomb, Madison, Mansfield, Maple Grove, Maplewood, Marietta, Marinette, Marion, Marlette, Marshalltown, Marshfield, Martinez, Martinsburg, Mattoon, Mayfield Heights, Maywood, Melrose Park, Mentor, Merced, Meridian, Middleburg Heights, Midland, Milwaukee, Minneapolis, Minocqua, Missoula, Monroe, Monticello, Morgantown, Morristown, Mount Vernon, Mukwonago, Murray, Muskegon, Nampa, Nashville, Nassau Bay, New Albany, Newark, Newberg, New Haven, New Orleans, New Richmond, New Ulm, New York, Niles, Normal, North Haven, Norton Shores, Novi, Oakland, Oak Lawn, Oconomowoc, Oconto Falls, O'Fallon, Ogden, Oklahoma City, Omaha, Ontario, Orange, Oregon City, Osage Beach, Oshkosh, Oswego, Ottawa, Overland Park, Pahrump, Papillion, Parker, Parkersburg, Park Rapids, Park Ridge, Pekin, Peoria, Perrysburg, Peru, Philadelphia, Phoenix, Pittsburg, Pittsburgh, Pontiac, Port Huron, Portland, Portsmouth, Port Townsend, Post Falls, Pottstown, Pottsville, Poulsbo, Princeton, Provo, Pueblo, Puyallup, Racine, Rancho Mirage, Rapid City, Redmond, Reed City, Reno, Renton, Rice Lake, Richardson, Richlands, Richmond, Riverton, Robbinsdale, Rochester, Rochester Hills, Rocklin, Rolla, Sacramento, Saginaw, Sainte Genevieve, Saint Joseph, Saint Louis Park, Saint Paul, Salinas, Salt Lake City, Sandpoint, Sandstone, Sandusky, San Luis Obispo, Santa Maria, Savannah, Scottsdale, Scranton, Seattle, Sedro-Woolley, Selinsgrove, Seneca, Shakopee, Shawano, Sheboygan, Shelby, Shelton, Shepherdsville, Sheridan, Shreveport, Silverdale, Sioux Falls, Skokie, Southfield, Spokane, Spokane Valley, Spooner, Springfield, Stamford, State College, Sterling Heights, Stevens Point, St. George, Stillwater, St Louis, Stockton, Sturgeon Bay, Sugar Land, Sullivan, Summit, Superior, Syracuse, Tacoma, Tawas City, The Woodlands, Thomasville, Thornton, Toledo, Topeka, Torrington, Traverse City, Troy, Trumbull, Tucson, Tulsa, Twin Falls, Two Rivers, Urbana, Valdosta, Vancouver, Verona, Virginia, Voorhees Township, Waconia, Walla Walla, Walnut Creek, Warren, Warrenville, Washington, Waterbury, Waterford, Waukee, Waukesha, Wauwatosa, West Allis, West Bloomfield, West Branch, West Des Moines, Westerly, Westerville, Westlake, Westminster, Weston, West Reading, Wheat Ridge, Wheeling, Wilkes-Barre, Willmar, Woodbury, Woodland, Wooster, Wyandotte, Wyoming, Yakima, Yelm, York Village, Yorkville, Youngstown, Ypsilanti, Zanesville
Age
18 years and over
People
288 worldwide
Run by
ECOG-ACRIN Cancer Research Group
See details and how to joinNCT03937635
Phase 3Taking people
Testing the Use of Combination Therapy in Adult Patients With Newly Diagnosed Multiple Myeloma, the EQUATE Trial
Where
Aberdeen, Adrian, Albuquerque, Allentown, Alma, Alpena, Alton, Ames, Anaconda, Anchorage, Ankeny, Ann Arbor, Appleton, Arroyo Grande, Athens, Auburn, Aurora, Baker City, Ballwin, Baraboo, Bardstown, Barrington, Baton Rouge, Battle Creek, Beachwood, Beavercreek, Bellingham, Belpre, Bemidji, Bend, Berkeley, Bethlehem, Billings, Binghamton, Bismarck, Bloomington, Boardman, Boise, Bolivar, Boone, Boston, Bozeman, Branson, Brighton, Brookfield, Bryan, Burbank, Burien, Burlingame, Burlington, Burnsville, Burr Ridge, Caldwell, Cambridge, Cameron Park, Camillus, Canton, Cape Girardeau, Carbondale, Carmel, Carmichael, Caro, Carroll, Carterville, Carthage, Castro Valley, Cedar Rapids, Centerville, Centralia, Chadds Ford, Chanute, Chardon, Charleston, Charlottesville, Chaska, Chelsea, Cherry Hill, Chesterfield, Cheyenne, Chicago, Chillicothe, Chilton, Chippewa Falls, Cincinnati, Clackamas, Clarkston, Cleveland, Clinton, Clive, Cody, Coeur d'Alene, Colorado Springs, Columbus, Coon Rapids, Coos Bay, Corbin, Council Bluffs, Creston, Crystal Lake, Cudahy, Danville, Davis, Dayton, Decatur, DeKalb, Delaware, Denver, Derby, Des Moines, Detroit, Dickson City, Dixon, Dodge City, Downers Grove, Dublin, Durango, East China Township, East Stroudsburg, East Syracuse, Eau Claire, Edina, Edmonds, Effingham, El Dorado, Elgin, Elk Grove, Elkton, Emmett, Englewood, Enumclaw, Escanaba, Eureka, Everett, Fairfax, Fairfield, Falls Church, Fargo, Farmington, Federal Way, Findlay, Flint, Fort Dodge, Fort Lauderdale, Fort Smith, Franklin, Frederick, Fremont, Fridley, Fruitland, Gahanna, Galesburg, Garden City, Geneva, Germantown, Gladwin, Glastonbury, Glens Falls, Goldsboro, Grafton, Grand Island, Grand Rapids, Great Bend, Great Falls, Green Bay, Greenville, Greenwich, Grosse Pointe Woods, Grove City, Guilford, Gulfport, Harrisburg, Hartford, Havre, Hazel Crest, Hazleton, Helena, Hershey, Homer Glen, Hood River, Hot Springs, Independence, Indianapolis, Issaquah, Jacksonville, Janesville, Jefferson, Jefferson City, Johnson Creek, Joplin, Kalamazoo, Kalispell, Kansas City, Kearney, Kenansville, Kennewick, Kenosha, Kettering, Kewanee, Kingman, Kinston, Lacey, La Crosse, Ladysmith, Lakewood, Lancaster, Lansing, Lewes, Lewisburg, Lexington, Liberal, Libertyville, Lima, Lincoln, Little Rock, Littleton, Livonia, London, Longmont, Longview, Louisville, Lynchburg, Macomb, Madison, Manhattan, Mansfield, Maple Grove, Maplewood, Marietta, Marinette, Marion, Marlette, Marshalltown, Marshfield, Marysville, Mattoon, Maumee, Mayfield Heights, Maywood, McPherson, Melrose Park, Mequon, Merced, Meriden, Meridian, Midland, Millville, Milwaukee, Minneapolis, Minocqua, Missoula, Modesto, Monroe, Monticello, Morristown, Mountain View, Mount Pleasant, Mount Sterling, Mount Vernon, Mukwonago, Muskegon, Nampa, Nashville, Neenah, Neillsville, New Albany, Newark, Newberg, New Britain, New Haven, New Richmond, Newton, New Ulm, Niles, Normal, North Haven, Norton Shores, Novato, Novi, Oak Lawn, Oconomowoc, Oconto Falls, O'Fallon, Oklahoma City, Omaha, Ontario, Orange, Oregon City, Osage Beach, Oshkosh, Ottawa, Palo Alto, Papillion, Parker, Park Ridge, Parma, Parsons, Pekin, Pensacola, Peoria, Perrysburg, Peru, Philadelphia, Phoenix, Pickerington, Pittsburg, Pontiac, Portland, Portsmouth, Post Falls, Pottsville, Poulsbo, Pratt, Princeton, Pueblo, Racine, Rapid City, Reading, Redmond, Reed City, Rehoboth Beach, Rice Lake, Richlands, Richmond, Robbinsdale, Rochester, Rochester Hills, Rockford, Rocklin, Rolla, Roseville, Sacramento, Saginaw, Saint Cloud, Sainte Genevieve, Saint Joseph, Saint Louis Park, Saint Paul, Salina, Salt Lake City, Sandpoint, San Francisco, San Luis Obispo, San Mateo, Santa Barbara, Santa Cruz, Santa Maria, Santa Rosa, Scranton, Seaford, Seattle, Sedro-Woolley, Sewell, Shakopee, Sheboygan, Shelton, Shepherdsville, Sheridan, Shreveport, Silverdale, Sioux City, Sioux Falls, Southfield, South Hill, Spokane, Springfield, Sterling Heights, Stevens Point, Stillwater, St Louis, Stockton, Stoneham, Stony Brook, Sturgeon Bay, Sullivan, Summit, Sunnyvale, Syracuse, Tacoma, Tawas City, Thief River Falls, Toledo, Torrington, Traverse City, Troy, Trumbull, Tucson, Twin Falls, Two Rivers, Urbana, Vallejo, Vancouver, Verona, Waconia, Wadsworth, Walla Walla, Warren, Warrenville, Washington, Washington D.C., Waterbury, Waterford, Waukee, Waukesha, Wausau, Wauwatosa, Wellington, West Allis, West Branch, West Chester, West Des Moines, Westerly, Westerville, West Islip, Westlake, Westminster, Weston, West Reading, White River Junction, Wichita, Wilkes-Barre, Willmar, Wilmington, Winfield, Wisconsin Rapids, Woodbury, Woodland, Wyoming, Yelm, Yorkville, Youngstown, Ypsilanti, Zanesville
Age
18 years and over
People
1,450 worldwide
Run by
ECOG-ACRIN Cancer Research Group
See details and how to joinNCT04566328
No phaseTaking people
Improving Cognitive Function in Older Adults Undergoing Stem Cell Transplant
Where
Omaha
Age
19 years and over
People
114
Run by
University of Nebraska
See details and how to joinNCT04898790
Phase 1/2Taking people
A Study to Investigate the Safety and Efficacy of Belantamab for the Treatment of Multiple Myeloma When Used as Monotherapy and in Combination Treatments
Where
Boston, Bullhead City, Canton, Chapel Hill, Chattanooga, Fort Worth, Grand Rapids, Los Angeles, Nashville, Pembroke Pines, Wilson
Age
18 years and over
People
123 worldwide
Run by
GlaxoSmithKline
See details and how to joinNCT05714839 · EU 2022-501941-63-00
Phase 2Taking people
Identifying Effective and Cost-Conscious Maintenance Daratumumab Dosing
Where
Nashville
Age
18 years to 70 years
People
50
Run by
Eden Biltibo
See details and how to joinNCT07485647
Phase 3Taking people
Inobrodib, Pomalidomide and Dexamethasone Versus Standard Available Therapy in Relapsed or Refractory Multiple Myeloma
Where
Miami
Age
18 years and over
People
450
Run by
CellCentric Ltd.
See details and how to joinNCT07772024
Phase 1/2Taking people
A Trial to Learn if Linvoseltamab is Safe and Works in Adults With Relapsed or Refractory Systemic Light Chain Amyloidosis (AL Amyloidosis)
Where
Boston, Buffalo, Columbus, Denver, Detroit, Duarte, Houston, Nashville
Age
18 years and over
People
220 worldwide
Run by
Regeneron Pharmaceuticals
See details and how to joinNCT06292780 · EU 2023-507809-34-00
Phase 2Taking people
IMMUNOPLANT for Newly Diagnosed Multiple Myeloma
Where
Miami
Age
18 years and over
People
150
Run by
Dickran Kazandjian, MD
See details and how to joinNCT06376526
Phase 2Taking people
Mezigdomide, Carfilzomib, and Dexamethasone for the Treatment of Relapsed or Refractory Multiple Myeloma in Patients With Extramedullary Disease
Where
Buffalo
Age
18 years and over
People
28
Run by
Roswell Park Cancer Institute
See details and how to joinNCT06627751
Early phase 1Taking people
A Pilot Study of Soursop Tea in Patients With Relapsed/Refractory Acute Myeloid Leukemia (AML) or Multiple Myeloma (MM)
Where
Camden
Age
18 years and over
People
20
Run by
Roger Strair
See details and how to joinNCT07771803
No phaseTaking people
DISCOVERY: Evaluating a Decision Support Tool for Adults Seen in Hematology/Oncology Clinics
Where
Chapel Hill
Age
60 years and over
People
500
Run by
UNC Lineberger Comprehensive Cancer Center
See details and how to joinNCT06296368
Phase 3Taking people
Study of AZD0120 in Newly Diagnosed Multiple Myeloma Ineligible for ASCT
Where
Albany, Atlanta, Aurora, Baltimore, Baton Rouge, Chapel Hill, Charlotte, Chicago, Cincinnati, Cleveland, Columbus, Coral Gables, Dallas, Denver, Detroit, Durham, East Brunswick, Fairfax, Gilbert, Houston, Iowa City, Louisville, Milwaukee, Montgomery, Nashville, New Haven, New Hyde Park, New York, Orange, Phoenix, Portland, Puyallup, Santa Monica, Seattle, St Louis, Tampa, The Bronx, Tucson, Wichita, Winston-Salem
Age
18 years and over
People
750 worldwide
Run by
AstraZeneca
See details and how to joinNCT07764978
Phase 1Taking people
SX-682 in Combination With Carfilzomib, Daratumumab-Hyaluronidase, and Dexamethasone in Patients With Relapsed or Refractory Multiple Myeloma
Where
Buffalo
Age
18 years and over
People
15
Run by
Roswell Park Cancer Institute
See details and how to joinNCT06622005
Phase 1Not yet taking people in United States
Allogeneic ORCA-Q Stem Cell Transplant for the Treatment of Relapsed and Refractory High Risk Multiple Myeloma
Where
Sacramento
Age
18 years to 65 years
People
20
Run by
University of California, Davis
See details and how to joinNCT07759102
No phaseEnrolling by invitation
MGUS/MM Awareness and Genetics Insights Campaign (MAGIC) Screening Study
Where
Rochester
Age
40 years and over
People
1,000
Run by
Mayo Clinic
See details and how to joinNCT06472830
Phase 4Taking people
Cosibelimab for CSCC in Patients With Kidney Transplant or Hematologic Malignancy
Where
Boston
Age
18 years and over
People
80
Run by
Dana-Farber Cancer Institute
See details and how to joinNCT07426484
Phase 1Taking people
Feasibility and Safety of Collecting and Combining Autologous Hematopoietic Stem Cells With Chimeric Antigen Receptor (CAR) T-Cell Therapy in Subjects With Relapsed/Refractory Hematological Malignancies
Where
Los Angeles
Age
18 years to 85 years
People
20
Run by
Joshua Sasine, MD, PhD
See details and how to joinNCT05887167
Phase 1Taking people
Phase I Trial of BCMA-TGF-BETA CAR-T Cells in Relapsed, Refractory Myeloma
Where
Milwaukee
Age
18 years to 80 years
People
30
Run by
Medical College of Wisconsin
See details and how to joinNCT05976555
Phase 1/2Taking people
Phase I/II Open Label Study of Belumosudil Mesylate Alone, and in Combination With Dexamethasone, in Patients With Relapsed/Refractory Multiple Myeloma
Where
Houston
Age
18 years and over
People
36
Run by
M.D. Anderson Cancer Center
See details and how to joinNCT06105554
Phase 2Taking people
Pre-transplant Purging and Post-transplant MRD-guided Maintenance Therapy With Elranatamab in Patients With High-risk Multiple Myeloma
Where
Houston
Age
18 years to 75 years
People
40
Run by
M.D. Anderson Cancer Center
See details and how to joinNCT06207799
No phaseTaking people
Delayed Toxicities Post-CAR-T
Where
New York, San Francisco
Age
18 years and over
People
30
Run by
Icahn School of Medicine at Mount Sinai
See details and how to joinNCT07665307
Phase 1/2Taking people
Phase I/II Study of CAR.70- Engineered IL15-transduced Cord Blood-derived NK Cells in Conjunction With Lymphodepleting Chemotherapy for the Management of Relapse/Refractory Hematological Malignances
Where
Houston
Age
12 years to 80 years
People
80
Run by
M.D. Anderson Cancer Center
See details and how to joinNCT05092451
Phase 2Taking people
Measurable Residual Disease-Guided Post-Transplant Elranatamab Maintenance
Where
St Louis
Age
18 years and over
People
65
Run by
Washington University School of Medicine
See details and how to joinNCT06483100
No phaseEnrolling by invitation
Predicting Progression of Developing Myeloma in a High-Risk Screened Population (PROMISE)
Where
Boston
Age
30 years and over
People
30,000
Run by
Dana-Farber Cancer Institute
See details and how to joinNCT03689595
No phaseTaking people
Study Using Prebiotics to Improve Gut Microbiome Diversity After Autologous Cellular Therapy
Where
Omaha
Age
19 years and over
People
30
Run by
University of Nebraska
See details and how to joinNCT05135351