Multiple sclerosis: open trials in United States

185 open trials have a site in United States. Registry data; only the trial team decides who can take part.

NCT07440446
Effect of Acetominophen an Gait Fatigue in Multiple Sclerosis
Research · Hunter College of City University of New York
Hunter College Physical Therapy department, New York
Registry updated 2026-03-17
NCT06809192
Factorial Optimization Trial to Test Cognitive Behavioral Therapy Components for Multiple Sclerosis Fatigue
Trial Treatment · University of Washington
Multiple Sclerosis Center at UW Medical Center - Northwest, Seattle
Registry updated 2026-03-16
NCT02521311
Assessment of Clemastine Fumarate as a Remyelinating Agent in Acute Optic Neuritis (ReCOVER)
Trial Treatment · Phase 2 · University of California, San Francisco
University of California San Francisco, San Francisco
Registry updated 2026-03-11
NCT06065670
Assessing Changes in Multi-parametric MRI in Patients With Acute Demyelinating Lesions Taking Clemastine Fumarate as a Myelin Repair Therapy
Trial Treatment · Phase 1/2 · University of California, San Francisco
Sandler Neurosciences Building, Neurological Clinical Research Unit, San Francisco
Registry updated 2026-03-11
NCT07447115
Exercise With and Without Cognitive Training
Trial Treatment · VA Office of Research and Development
Atlanta VA Medical and Rehab Center, Decatur, GA, Decatur
Registry updated 2026-03-03
NCT06138132
A Study of Anti-CD19 Chimeric Antigen Receptor T-Cell ( CAR-T) Therapy in Subjects With Non-relapsing and Progressive Forms of Multiple Sclerosis
Trial Treatment · Phase 1 · Stanford University
Stanford Multiple Sclerosis Center, Palo Alto
Registry updated 2026-02-27
NCT05433103
Blood Flow Restriction And Veterans With MS
Trial Treatment · VA Office of Research and Development
Rocky Mountain Regional VA Medical Center, Aurora, CO, Aurora
Registry updated 2026-02-23
NCT06390930
Effects of Acute Intermittent Hypoxia on Neuroplasticity in MS
Trial Treatment · Shirley Ryan AbilityLab
Shirley Ryan AbilityLab, Chicago
Registry updated 2026-02-23
NCT07424027
Central Vein Sign in Multiple Sclerosis Extension Study
Trial Treatment · The Cleveland Clinic
Cleveland Clinic Foundation, Cleveland · Cedars-Sinai Medical Center, Los Angeles · University of Pennsylvania, Philadelphia
Registry updated 2026-02-20
NCT07415824
Multiple Sclerosis Implementation Network (Registry)
Research · The University of Texas Health Science Center, Houston
The University of Texas at Austin, Austin · Multiple Sclerosis Association of America, Cherry Hill · The University of Texas Health Science Center at Houston (UTHealth Houston), Houston
Registry updated 2026-02-17
NCT07392879
Bringing the Outdoors In: Virtual Nature Walks for Depression in Multiple Sclerosis (MS) Patients
Trial Treatment · University of Michigan
University of Michigan, Ann Arbor
Registry updated 2026-02-12
NCT07403188
A Long-Term Follow-Up Study for Participants Previously Treated With KYV-101
Research · Phase 2/3 · Kyverna Therapeutics
University of Colorado Denver, Denver
Registry updated 2026-02-11
NCT03291756
CorEvitas Multiple Sclerosis (MS) Registry
Research · CorEvitas
CorEvitas, LLC, Waltham
Registry updated 2026-02-09
NCT06629428
Effects of Ublituximab on Motor Functions in Multiple Sclerosis
Trial Treatment · Early phase 1 · Georgia State University
Atlanta Neuroscience Institute, Atlanta · Georgia State University, Atlanta
Registry updated 2026-02-09
NCT03233646
Retinal Imaging in Neurodegenerative Disease
Research · Duke University
Duke University Medical Center, Durham
Registry updated 2026-02-04
NCT03207464
Molecular Imaging of NET Using [C-11]MRB-PET in MS
Trial Treatment · Phase 1/2 · Brigham and Women's Hospital
Brigham MS Center, 60 Fenwood Road, Boston
Registry updated 2026-02-02
NCT02649985
PET Brain Imaging in Multiple Sclerosis, Alzheimer's Disease, and Other Neurological and Neuropsychiatric Diseases
Trial Treatment · Phase 1/2 · Brigham and Women's Hospital
Brigham MS Center, 60 Fenwood Road, Boston
Registry updated 2026-01-28
NCT04806620
Unhide® Project: A Digital Health Platform to Collect Lifestyle Data for Brain Inflammation Research
Research · Brain Inflammation Collaborative
Brain Inflammation Collaborative, Delafield
Registry updated 2026-01-22
NCT07355387
Home Based Functional Balance Intervention for Multiple Sclerosis
Trial Treatment · University of Illinois Chicago
University of Illinois at Chicago, Chicago
Registry updated 2026-01-21
NCT02402426
Brain Health Registry: An Online Registry to Identify and Assess Subjects for Brain Research
Research · University of California, San Francisco
BrainHealthRegistry.org, San Francisco
Registry updated 2026-01-13
NCT04634994
Assessment of Synaptic Density in MS
Trial Treatment · Early phase 1 · Brigham and Women's Hospital
Brigham and Women's Hospital, Boston
Registry updated 2026-01-09
NCT05162638
Immune Profiles in Multiple Sclerosis (MS) Patients and Healthy Volunteers Through Thoracic Duct Cannulation
Trial Treatment · University of Pennsylvania
University of Pennsylvania, Philadelphia
Registry updated 2026-01-09
NCT07087106
Glucose Consumption in MS Using [F-18]FDG-PET
Trial Treatment · Phase 4 · Brigham and Women's Hospital
Brigham & Women's Hospital, Boston
Registry updated 2026-01-09
NCT06261528
Study of Circadian Focused Light Therapy in Progressive Multiple Sclerosis
Trial Treatment · Phase 1 · University of Texas Southwestern Medical Center
UT Southwestern Medical Center, Dallas
Registry updated 2025-12-31
NCT02994121
Prospective Investigation of Multiple Sclerosis in the Three Rivers Region
Research · University of Pittsburgh
University of Pittsburgh, Pittsburgh
Registry updated 2025-12-29

All Multiple sclerosis trials and the map

This page is not medical advice. Talk to your doctor before contacting a trial.

Report an error