Myelodysplastic syndromes trials in Canada

In Canada 20 Also abroad 369

20 trials · From ClinicalTrials.gov, checked 11 November 2026. Ask the study team whether a trial fits you.

Phase 2Taking people
Testing New Therapies for Patients With Acute Myeloid Leukemia Who Are Newly Diagnosed and Have Not Yet Started Treatment (A MyeloMATCH Treatment Trial)
Where
Calgary, Edmonton, Greenfield Park, Halifax, Montreal, Ottawa, Toronto, Winnipeg
Age
18 years to 59 years
People
335 worldwide
Run by
National Cancer Institute (NCI)
See details and how to joinNCT05554406
Phase 3Taking people
A Study of Elritercept to Treat Anemia in Adults With Very Low, Low, or Intermediate Risk Myelodysplastic Syndromes (MDS) Who Need Regular Blood Transfusions
Where
Edmonton, Halifax, London, Toronto, Vancouver
Age
18 years and over
People
225 worldwide
Run by
Takeda
See details and how to joinNCT06499285 · EU 2024-516009-22-00
Phase 2Taking people
MYELOMATCH: A Screening Study to Assign People With Myeloid Cancer to a Treatment Study or Standard of Care Treatment Within myeloMATCH (MyeloMATCH Screening Trial)
Where
Calgary, Edmonton, Greenfield Park, Halifax, Hamilton, Montreal, Ottawa, Toronto, Winnipeg
Age
18 years and over
People
2,000 worldwide
Run by
National Cancer Institute (NCI)
See details and how to joinNCT05564390
No phaseTaking people
Collection of Tissue Samples for Cancer Research
Where
Toronto
Age
2 months and over
People
5,000 worldwide
Run by
National Cancer Institute (NCI)
See details and how to joinNCT00900198
Phase 1/2Taking people
Study of AZD3632 Monotherapy or in Combination With Anticancer Agents in Participants With Advanced Haematologic Malignancies With KMT2Ar, NPM1m, or Other Genotypes Associated With HOX Overexpression
Where
Montreal, Toronto
Age
16 years and over
People
85 worldwide
Run by
AstraZeneca
See details and how to joinNCT07155226 · EU 2025-521299-76-00
Phase 2Taking people
A Study to Assess the Effectiveness and Safety of Pacritinib in Patients With VEXAS Syndrome (PAXIS)
Where
Halifax, Montreal, Toronto, Vancouver
Age
18 years and over
People
156 worldwide
Run by
Swedish Orphan Biovitrum
See details and how to joinNCT06782373 · EU 2024-516347-41-00
Phase 3Taking people
Lisaftoclax (APG-2575) Combined With Azacytidine (AZA) in the Treatment of Patients With Higher-risk Myelodysplastic Syndrome (GLORA-4).
Where
Calgary, Montreal, Toronto, Vancouver
Age
18 years and over
People
490 worldwide
Run by
Ascentage Pharma Group Inc.
See details and how to joinNCT06641414 · EU 2024-517247-31-00
Phase 2/3Taking people
A Multi-phase Study of ASTX030 (Azacitidine and Cedazuridine) in Myeloid Neoplasm Alone or in Combination With Venetoclax in AML (AZTOUND Study)
Where
St. John's, Toronto
Age
18 years and over
People
316 worldwide
Run by
Taiho Oncology, Inc.
See details and how to joinNCT04256317 · EU 2024-515098-93-00
Phase 2Taking people
(Apex) Bezuclastinib in Patients With Advanced Systemic Mastocytosis
Where
Edmonton, Toronto
Age
18 years and over
People
140 worldwide
Run by
Cogent Biosciences, Inc.
See details and how to joinNCT04996875 · EU 2024-511407-42-00
Phase 1/2Taking people
The Pediatric Acute Leukemia (PedAL) Screening Trial - A Study to Test Bone Marrow and Blood in Children With Leukemia That Has Come Back After Treatment or Is Difficult to Treat - A Leukemia & Lymphoma Society and Children's Oncology Group Study
Where
Calgary, Edmonton, Halifax, London, Montreal, Ottawa, Québec, Sherbrooke, Toronto, Vancouver, Winnipeg
Age
Up to 22 years
People
960 worldwide
Run by
PedAL BCU, LLC
See details and how to joinNCT04726241
Phase 2Enrolling by invitation
A Study for Participants Who Participated in Prior Clinical Studies of ASTX727 (Standard Dose)
Where
Edmonton, Nova Scotia, Ottawa, Toronto
Age
18 years and over
People
332 worldwide
Run by
Taiho Oncology, Inc.
See details and how to joinNCT04093570 · EU 2024-516293-29-01
Phase 3Taking people
A Study to Evaluate Long-term Safety in Participants Who Have Participated in Other Luspatercept (ACE-536) Clinical Trials
Where
Toronto
Age
18 years and over
People
665 worldwide
Run by
Celgene
See details and how to joinNCT04064060
Phase 2Not yet taking people in Canada
Evaluation of Antibiotic Prophylaxis in Myelodysplastic Syndromes and Acute Myeloid Leukemia (MYELO-CAN:ABX)
Where
Winnipeg
Age
18 years and over
People
75
Run by
University of Manitoba
See details and how to joinNCT07528417
Phase 2Taking people
A Study of Momelotinib in Participants With Low-risk Myelodysplastic Syndrome
Where
Calgary, Toronto
Age
18 years and over
People
80 worldwide
Run by
GlaxoSmithKline
See details and how to joinNCT06847867 · EU 2024-519928-24-00
Phase 2Taking people
Evaluation of Tranexamic Acid in Myelodysplastic Syndromes and Acute Myeloid Leukemia
Where
Winnipeg
Age
18 years and over
People
75
Run by
University of Manitoba
See details and how to joinNCT06599762
Phase 1/2Taking people
A Phase 1/2 Study of Enzomenib (DSP-5336) in Patients With Acute Leukemia (Horizen-1)
Where
Calgary, Edmonton
Age
12 years and over
People
606 worldwide
Run by
Sumitomo Pharma America, Inc.
See details and how to joinNCT04988555
No phaseTaking people
Evaluating Myelodysplastic Syndrome Risks in NET Patients Planned for Peptide Radionuclide Therapy
Where
Toronto
People
45
Run by
University Health Network, Toronto
See details and how to joinNCT06510868
Phase 1/2Taking people
A Study Testing an Improved Dose of UM171 to Help Make Cord Blood Transplants More Effective and Safe.
Where
Montreal
Age
18 years to 67 years
People
7
Run by
Ciusss de L'Est de l'Île de Montréal
See details and how to joinNCT07301866
No phaseTaking people
OURA Ring Wearable Testing in MDS Patients: a Feasibility and Discovery Pilot Study
Where
Toronto
Age
18 years and over
People
60
Run by
Sunnybrook Health Sciences Centre
See details and how to joinNCT06270771
No phaseTaking people
Myeloproliferative Neoplasms (MPNs) Patient Registry
Where
Toronto
People
5,000
Run by
University Health Network, Toronto
See details and how to joinNCT02760238