Myelodysplastic syndromes trials in United States

In United States 224 Also abroad 369

224 trials · From ClinicalTrials.gov, checked 12 November 2026. Ask the study team whether a trial fits you.

Phase 1Taking people
225Ac-DOTA-Anti-CD38 Daratumumab Monoclonal Antibody With Fludarabine, Melphalan and Total Marrow and Lymphoid Irradiation as Conditioning Treatment for Donor Stem Cell Transplant in Patients With High-Risk Acute Myeloid Leukemia, Acute Lymphoblastic Leukemia and Myelodysplastic Syndrome
Where
Duarte
Age
18 years to 70 years
People
15
Run by
City of Hope Medical Center
See details and how to joinNCT06287944
No phaseTaking people
A Long-term Follow-up Study of Patients With ARD103 CAR-T Cell Therapies
Where
Charlotte, Houston, Winston-Salem
People
49
Run by
ARCE Therapeutics, Inc.
See details and how to joinNCT06906380
No phaseTaking people
Mosaic Trial for Stem Cell Transplant Recipients
Where
Chicago, Nutley, Washington D.C.
Age
18 years and over
People
356
Run by
Northwestern University
See details and how to joinNCT06960993
No phaseTaking people
Natural History Study of GATA2 Deficiency and Related Disorders
Where
Bethesda
Age
2 years to 100 years
People
600
Run by
National Institute of Allergy and Infectious Diseases (NIAID)
See details and how to joinNCT01905826
No phaseTaking people
Cancer Experience Registry (CER) for Cancer Patients and Caregivers
Where
Washington D.C.
Age
18 years and over
People
15,000
Run by
Cancer Support Community, Research and Training Institute, Philadelphia
See details and how to joinNCT02333604
Phase 2Taking people
Trial of 2 Step ATG for Prevention of Acute GVHD Post Allogeneic Stem Cell Transplant
Where
Birmingham
Age
18 years to 75 years
People
56
Run by
University of Alabama at Birmingham
See details and how to joinNCT06265584
Phase 1Taking people
Study of REM-422 in Patients With AML or Higher Risk MDS
Where
Boston, Duarte, Houston, New York, Tampa
Age
18 years and over
People
100 worldwide
Run by
Remix Therapeutics
See details and how to joinNCT06297941
Phase 1Taking people
Prophylactic DLI-X for Leukemia Relapse After HCT
Where
Tucson
Age
Up to 65 years
People
180
Run by
University of Arizona
See details and how to joinNCT07254793
Phase 1Not yet taking people in United States
Allogeneic iNKT Cell Therapy (agenT-797) After SCT
Where
Madison
Age
18 years and over
People
22
Run by
University of Wisconsin, Madison
See details and how to joinNCT07758218
No phaseTaking people
Tissue, Blood, and Body Fluid Sample Collection From Patients With Hematologic Cancer
Where
Chapel Hill
Age
18 years to 120 years
People
15,000
Run by
UNC Lineberger Comprehensive Cancer Center
See details and how to joinNCT01137643
Phase 1/2Taking people
CLN-049 in Patients With Relapsed/Refractory Acute Myeloid Leukemia (AML) or Myelodysplastic Syndrome (MDS)
Where
Atlanta, Aurora, Birmingham, Boston, Buffalo, Cincinnati, Duarte, Durham, Houston, Jacksonville, Los Angeles, Miami, New York, Phoenix, Rochester, Tampa
Age
18 years and over
People
275
Run by
Cullinan Therapeutics Inc.
See details and how to joinNCT05143996
No phaseTaking people
HEME Home Transfusion Program
Where
Boston
Age
18 years and over
People
700
Run by
Dana-Farber Cancer Institute
See details and how to joinNCT06487247
Phase 2Not yet taking people in United States
Study of Allogeneic Stem Cell Transplant in Myelodysplastic Syndrome Following Conditioning With Fludarabine and Total Body Irradiation 800 cGy
Where
Los Angeles
People
20
Run by
Ronald Paquette
See details and how to joinNCT07896928
No phaseTaking people
Collection of Tissue Samples for Cancer Research
Where
Ann Arbor, Atlanta, Aurora, Baltimore, Bethesda, Buffalo, Charleston, Charlottesville, Columbus, Indianapolis, Iowa City, Pittsburgh, Sacramento, Salt Lake City, Seattle, St Louis
Age
2 months and over
People
5,000 worldwide
Run by
National Cancer Institute (NCI)
See details and how to joinNCT00900198
Phase 1Taking people
Alpha/Beta CD19+ Depleted Haploidentical Transplantation + Zometa for Pediatric Hematologic Malignancies and Solid Tumors
Where
Madison
Age
7 months to 21 years
People
22
Run by
University of Wisconsin, Madison
See details and how to joinNCT02508038
Phase 2Taking people
Cord Blood Transplant, Cyclophosphamide, Fludarabine, and Total-Body Irradiation in Treating Patients With High-Risk Hematologic Diseases
Where
Seattle
Age
6 months to 65 years
People
54
Run by
Fred Hutchinson Cancer Center
See details and how to joinNCT06013423
Phase 2Taking people
CMV-MVA Triplex Vaccination in HLA-Matched Related Stem Cell Donors for the Prevention of CMV Infection in Patients Undergoing Hematopoietic Stem Cell Transplant
Where
Atlanta, Boston, Duarte
Age
18 years to 75 years
People
216
Run by
City of Hope Medical Center
See details and how to joinNCT06059391
Phase 1Taking people
A Vaccine (CMV-MVA Triplex Vaccine) for the Enhancement of CMV-Specific Immunity and the Prevention of CMV Viremia in Patients Undergoing Haploidentical Hematopoietic Stem Cell Transplant
Where
Atlanta, Boston, Duarte
Age
18 years to 75 years
People
46
Run by
City of Hope Medical Center
See details and how to joinNCT07020533
Phase 1/2Taking people
Study of AZD3632 Monotherapy or in Combination With Anticancer Agents in Participants With Advanced Haematologic Malignancies With KMT2Ar, NPM1m, or Other Genotypes Associated With HOX Overexpression
Where
Chapel Hill, Decatur, Durham, Houston, New York, Portland
Age
16 years and over
People
85 worldwide
Run by
AstraZeneca
See details and how to joinNCT07155226 · EU 2025-521299-76-00
Phase 1/2Taking people
Study of DISC-0974 (RALLY-MF) in Participants With Myelofibrosis or Myelodysplastic Syndrome and Anemia
Where
Ann Arbor, Atlanta, Aurora, Canton, Cleveland, Columbus, Duarte, East Brunswick, Gettysburg, Gilbert, Houston, Iowa City, Irvine, Jacksonville, Los Angeles, Maumee, Miami, Milwaukee, New York, Philadelphia, Portland, Rochester, Rolling Meadows, San Francisco, Seattle, St Louis, Tampa, Temple, Winston-Salem
Age
18 years and over
People
150 worldwide
Run by
Disc Medicine, Inc
See details and how to joinNCT05320198
No phaseEnrolling by invitation
Biology Studies of Hematologic Cancers
Where
Bethesda
Age
1 year to 120 years
People
550
Run by
National Cancer Institute (NCI)
See details and how to joinNCT00923442
Phase 1Taking people
CER-1236 in Patients With Acute Myeloid Leukemia (AML), Myelodysplastic Syndrome (MDS), and Myelofibrosis (MF)
Where
Denver, Houston, Nashville, Sacramento, Seattle
Age
18 years to 85 years
People
18
Run by
CERo Therapeutics Holdings, Inc.
See details and how to joinNCT06834282
Phase 1Taking people
Therapeutic RSK1 Targeting in Myeloid Malignancies
Where
St Louis
Age
18 years and over
People
30
Run by
Washington University School of Medicine
See details and how to joinNCT07379125
Phase 2Taking people
Graft Versus Host Disease-Reduction Strategies for Donor Blood Stem Cell Transplant Patients With Acute Leukemia or Myelodysplastic Syndrome (MDS)
Where
Pittsburgh, Seattle, Tampa
Age
1 year to 60 years
People
120
Run by
Fred Hutchinson Cancer Center
See details and how to joinNCT03970096
Phase 1Taking people
Eganelisib as Monotherapy and in Combination With Cytarabine in Relapsed/Refractory AML/HR-MDS and in Combination With Azacitidine in Previously Untreated HR-MDS
Where
Aurora, Boston, Cleveland, Columbus, Duarte, Houston, New York, St Louis, Tampa
Age
18 years and over
People
105 worldwide
Run by
Stelexis BioSciences
See details and how to joinNCT06533761 · EU 2024-518071-58-00