Obesity trials in Canada

In Canada 99 Also abroad 1939

99 trials · From ClinicalTrials.gov, checked 11 November 2026. Ask the study team whether a trial fits you.

Phase 3Taking people
A Master Protocol to Investigate Efficacy and Safety of Elecoglipron in Participants With Obesity or Overweight With or Without T2DM
Where
Brampton, Calgary, Hamilton, Joliette, Moncton, Montreal, Niagara Falls, North York, Saint-Lambert, Sarnia, Scarborough Village, Stouffville, Terrebonne, Toronto, Truro, Vancouver, Victoria
Age
18 years and over
People
4,500 worldwide
Run by
AstraZeneca
See details and how to joinNCT07667803
Phase 2Taking people
Effects of Different Fish Oil Types on Type 2 Diabetes Risk Factors in High-Risk Adults
Where
Montreal
Age
40 years to 70 years
People
84
Run by
May Faraj, PDt, PhD
See details and how to joinNCT07575438
No phaseTaking people
Visceral Adipose Tissue and Liver Changes Associated With Semaglutide in CKD
Where
Edmonton
Age
18 years and over
People
52
Run by
University of Alberta
See details and how to joinNCT07187830
Phase 3Not yet taking people in Canada
A Research Study to Look at How Well Zenagamtide Works Compared to Placebo in People With Established Atherosclerotic Cardiovascular Disease and Either Overweight or Obesity
Where
Ajax, Chicoutimi, Edmonton, Joliette, London, Mirabel, Mississauga, Moncton, Montreal, North York, Peterborough, Québec, Red Deer, Saint-Charles-Borromée, Sherbrooke, Terrebonne, Toronto, Truro, Vancouver
Age
45 years to 64 years
People
8,500 worldwide
Run by
Novo Nordisk A/S
See details and how to joinNCT07861100 · EU 2026-525182-53-00
Phase 3Taking people
Extension Trial to Evaluate the Long-term Efficacy, Safety, and Tolerability of Maridebart Cafraglutide (MARITIME-2-EXTENSION)
Where
Hamilton
Age
18 years to 99 years
People
950 worldwide
Run by
Amgen
See details and how to joinNCT07684144 · EU 2025-524788-19-00
Phase 3Taking people
Extension Trial to Evaluate the Long-term Efficacy, Safety, and Tolerability of Maridebart Cafraglutide (MARITIME-1-EXTENSION)
Where
Chicoutimi, Hamilton, Thunder Bay
Age
18 years to 99 years
People
3,200 worldwide
Run by
Amgen
See details and how to joinNCT07684235
Phase 4Not yet taking people in Canada
Patient-centred Intervention With Virtual Support for Obesity and Kidney Transplant Access
Where
London
Age
18 years and over
People
880
Run by
Kristin Clemens
See details and how to joinNCT07858331
No phaseTaking people
A Clinical Trial to Investigate the Safety and Efficacy of MB-1 on Metabolic Health in Overweight and Obese Adults
Where
London
Age
18 years to 50 years
People
120
Run by
Arrae
See details and how to joinNCT07363148
Phase 3Taking people
A Research Study to Look at How Two Different Doses of CagriSema and One Dose of Semaglutide Help People Living With Obesity With or Without Type 2 Diabetes Lose Weight
Where
Brampton, Calgary, Guelph, Halifax, Hamilton, Kelowna, London, Moncton, Montreal, Pointe-Claire, Québec, Sarnia, Surrey, Sydney, Toronto, Victoria
Age
18 years and over
People
2,500 worldwide
Run by
Novo Nordisk A/S
See details and how to joinNCT07564414 · EU 2025-522488-14-00
No phaseNot yet taking people in Canada
A Two-part Study of Lembas Edge Evaluating Tolerability and Postprandial Glycemic Control
Where
London
Age
18 years and over
People
35
Run by
Lembas
See details and how to joinNCT07711288
Phase 3Taking people
A Study of Tirzepatide in Adolescents With Obesity and Weight-Related Comorbidities (SURMOUNT-ADOLESCENTS-2)
Where
Hamilton, Sarnia
Age
12 years to 17 years
People
300 worldwide
Run by
Eli Lilly and Company
See details and how to joinNCT06439277
Phase 3Taking people
AMAZE 1: A Research Study Investigating How Well the Medicine NNC0487-0111 Helps People With Excess Body Weight Lose Weight
Where
Calgary, Halifax, London, Moncton, Surrey
Age
18 years and over
People
1,150 worldwide
Run by
Novo Nordisk A/S
See details and how to joinNCT07339423 · EU 2024-520440-42-00
No phaseNot yet taking people in Canada
Physical Activity for Depressive Symptoms in Adults With Obesity: A Randomized Controlled Feasibility Trial
Where
Gatineau, Montreal, Québec
Age
18 years and over
People
26
Run by
Universite du Quebec en Outaouais
See details and how to joinNCT07836582
Phase 3Taking people
A Study of Eloralintide (LY3841136) in Participants With Obesity, or Overweight Without Type 2 Diabetes
Where
Brampton, Courtice, Guelph, Hamilton, Québec, Sarnia, Stoney Creek, Trois-Rivières
Age
18 years and over
People
1,980 worldwide
Run by
Eli Lilly and Company
See details and how to joinNCT07321886 · EU 2025-523657-34-00
No phaseNot yet taking people in Canada
Applying Navigation and Care to Help Ongoing Retention
Where
Edmonton
Age
6 years to 17 years
People
252
Run by
University of Alberta
See details and how to joinNCT07834632
No phaseEnrolling by invitation
Cities for Better Health Childhood Obesity Prevention Initiative
Where
Mississauga
Age
6 years to 13 years
People
36,000 worldwide
Run by
Novo Nordisk A/S
See details and how to joinNCT06855563
Phase 3Taking people
A Study of Once-daily Oral ASC30 to Evaluate the Efficacy and Safety in Adult Participants With Obesity or Overweight With Weight-Related Comorbidities
Where
Burlington
Age
18 years and over
People
3,003 worldwide
Run by
Ascletis Pharma (China) Co., Limited
See details and how to joinNCT07743463
No phaseTaking people
Investigating the Combined Effects of Protein, Blueberries, and Exercise on Cardiovascular Health and Frailty in Older Nova Scotians
Where
Halifax
Age
65 years and over
People
240
Run by
Nova Scotia Health Authority
See details and how to joinNCT06693271
Phase 1Taking people
A Research Study Looking Into How UBT251 Works With Birth Control Tablets and Emptying of the Stomach in Women With Excess Body Weight Not Able to Become Pregnant
Where
Montreal
Age
18 years to 65 years
People
40
Run by
Novo Nordisk A/S
See details and how to joinNCT07710729
Phase 3Taking people
A Research Study to Look at How Well NNC0487-0111 Works Compared to Placebo in People With Heart Failure and Obesity
Where
Burlington, Calgary, Chicoutimi, Courtice, Halifax, Hamilton, Kingston, Moncton, Montreal, North York, Oakville, Peterborough, Québec, Rimouski, Saint-Charles-Borromée, Scarborough Village, Sherbrooke, Toronto, Trois-Rivières, Vancouver, Waterloo, Winchester, Winnipeg
Age
18 years and over
People
5,610 worldwide
Run by
Novo Nordisk A/S
See details and how to joinNCT07567001 · EU 2025-523717-29-00
Phase 3Taking people
AMAZE 6: A Research Study Investigating How Well the Medicine NNC0487-0111 Helps People With Excess Body Weight and Knee Osteoarthritis Lose Weight and Reduce Pain
Where
Lévis, Montreal, Niagara Falls, Québec, Sherbrooke, Surrey
Age
18 years and over
People
400 worldwide
Run by
Novo Nordisk A/S
See details and how to joinNCT07509307 · EU 2024-520445-23-00
Phase 4Not yet taking people in Canada
GLP-1s in Hip and Knee Arthroplasty
Where
Dartmouth
Age
18 years to 90 years
People
100
Run by
Nova Scotia Health Authority
See details and how to joinNCT07755085
Phase 4Taking people
Fibrosis Lessens After Metabolic Surgery
Where
Montreal
Age
18 years to 75 years
People
120 worldwide
Run by
The Cleveland Clinic
See details and how to joinNCT06374875
No phaseNot yet taking people in Canada
Weight Loss and Hunger
Where
Ottawa
Age
18 years to 55 years
People
40
Run by
University of Ottawa
See details and how to joinNCT07739095
No phaseTaking people
Impact of Semaglutide (Ozempic/Wegovy®) on Heart and Muscle Mass
Where
Edmonton
Age
18 years to 80 years
People
50
Run by
University of Alberta
See details and how to joinNCT07272837