Opioid use disorder trials in United States

In United States 229 Also abroad 254

229 trials · From ClinicalTrials.gov, checked 15 November 2026. Ask the study team whether a trial fits you.

No phaseTaking people
Opioid Use Disorder in Pregnancy in Long-Term Maternal/Infant Outcomes
Where
Pittsburgh
Age
18 years and over
People
600
Run by
Senthil Sadhasivam
See details and how to joinNCT03923374
No phaseNot yet taking people in United States
Trauma-informed, Resilience-based Telehealth Intervention for Improving HIV Prevention and HCV Care for Persons Who Inject Drugs in the Deep South (Pilot Testing: Aim3)
Where
Colbert
Age
18 years and over
People
50
Run by
University of Georgia
See details and how to joinNCT06799702
No phaseTaking people
Intervening on Opioid Use and Loneliness
Where
Rochester
Age
18 years and over
People
300
Run by
University of Rochester
See details and how to joinNCT06458335
No phaseTaking people
Integrating Brain, Neurocognitive, and Computational Tools in OUD
Where
Philadelphia
Age
18 years to 60 years
People
192
Run by
University of Pennsylvania
See details and how to joinNCT06136247
No phaseTaking people
NavSTAR Implementation Effectiveness Trial Across a Health System
Where
Philadelphia
Age
18 years and over
People
720
Run by
Friends Research Institute, Inc.
See details and how to joinNCT07262190
No phaseTaking people
Integrated Treatment for Opioid Use Disorder and PTSD
Where
Charleston
Age
18 years to 70 years
People
76
Run by
Medical University of South Carolina
See details and how to joinNCT06641115
No phaseTaking people
Expanding the Youth Opioid Recovery Support (YORS) Intervention for MOUD Adherence to Adolescents With OUD
Where
Baltimore
Age
13 years to 21 years
People
80
Run by
Potomac Health Foundations
See details and how to joinNCT06774248
Phase 2Not yet taking people in United States
Dynamic Treatment Regimes for Opioid Use Disorder
Where
Irvine
Age
18 years and over
People
75
Run by
Brigham and Women's Hospital
See details and how to joinNCT07011758
No phaseTaking people
Individualized Adaptive Deep Brain Stimulation in Opioid Use Disorder
Where
San Francisco
Age
22 years to 75 years
People
6
Run by
University of California, San Francisco
See details and how to joinNCT07214467
Phase 2/3Taking people
Identifying Optimal Buprenorphine Dosing for Opioid Use Disorder Treatment and Prevention of Overdose
Where
Providence
Age
18 years and over
People
250
Run by
Rhode Island Hospital
See details and how to joinNCT06316830
No phaseTaking people
Emergency Medicine Peer Outreach Worker Engagement for Recovery
Where
Providence
Age
18 years and over
People
400
Run by
University of California, Los Angeles
See details and how to joinNCT06320015
Phase 4Enrolling by invitation
Houston Emergency Opioid Engagement System
Where
Houston
Age
18 years and over
People
3,000
Run by
The University of Texas Health Science Center, Houston
See details and how to joinNCT03396276
Phase 4Taking people
Young Houston Emergency Opioid Engagement System
Where
Houston
Age
13 years to 17 years
People
250
Run by
The University of Texas Health Science Center, Houston
See details and how to joinNCT04811014
No phaseNot yet taking people in United States
Enhancing Recovery Capital Amid Opioid Use Disorder Pharmacotherapy: A Pilot Randomized Trial
Where
Boston
Age
18 years and over
People
145
Run by
Massachusetts General Hospital
See details and how to joinNCT05245513
No phaseTaking people
The Youth Opioid Recovery Support (YORS) Intervention
Where
Baltimore
Age
18 years to 28 years
People
150
Run by
Potomac Health Foundations
See details and how to joinNCT04173416
Phase 1Taking people
Right Tools, Right Time, Right Place: Telehealth for Opioid Use Disorder in Vulnerable Settings
Where
Portland
Age
18 years and over
People
250
Run by
Boulder Care
See details and how to joinNCT07169409
No phaseTaking people
AvertD Post-Approval Study
Where
Indianapolis
Age
18 years and over
People
4,000
Run by
Prescient Medicine Holdings, Inc.
See details and how to joinNCT07135323
Phase 1Taking people
Combined Guanfacine and Mindfulness Meditation as an Adjunct to Buprenorphine Maintenance in Opioid Use Disorder
Where
Newark
Age
18 years to 55 years
People
224
Run by
Rutgers, The State University of New Jersey
See details and how to joinNCT06642181
Phase 3Taking people
Implementation and Effectiveness of Mindfulness Oriented Recovery Enhancement as an Adjunct to Methadone Treatment
Where
New Brunswick, Salt Lake City
Age
18 years and over
People
450
Run by
Rutgers, The State University of New Jersey
See details and how to joinNCT06032559
No phaseTaking people
Disclosure Intervention for People in Treatment for Opioid Use Disorder
Where
Wilmington
Age
18 years and over
People
480
Run by
University of Delaware
See details and how to joinNCT06458985
No phaseTaking people
Long-Term Treatment of Opioid Use Disorder
Where
Marquette
Age
18 years and over
People
225
Run by
Northern Michigan University
See details and how to joinNCT05534815
No phaseTaking people
EXPANDED SCOPE for Parent Grant Entitled, "Peer Recovery Support Services for Individuals in Recovery Residences on MOUD"
Where
Baltimore
Age
18 years and over
People
35
Run by
Potomac Health Foundations
See details and how to joinNCT06696157
No phaseTaking people
Brain Training for Substance Use Disorders
Where
Minneapolis
Age
18 years to 65 years
People
40
Run by
Neurotype Inc.
See details and how to joinNCT06870110
No phaseEnrolling by invitation
Assessing Concentrations of Methadone and Its Metabolites
Where
Lemon Grove
Age
18 years to 70 years
People
20
Run by
Cari Health Inc.
See details and how to joinNCT06835582
No phaseTaking people
Postpartum Intervention for Mothers With Opioid Use Disorders
Where
Ann Arbor, Stony Brook
Age
18 years to 50 years
People
50
Run by
Stony Brook University
See details and how to joinNCT05614661