Osteoarthritis trials in United States

In United States 226 Also abroad 827

226 trials · From ClinicalTrials.gov, checked 13 November 2026. Ask the study team whether a trial fits you.

No phaseTaking people
Prospective Observational Study Of Geniculate Artery Embolization For Symptomatic Knee Osteoarthritis In A Cancer Population
Where
Houston
Age
40 years and over
People
50
Run by
M.D. Anderson Cancer Center
See details and how to joinNCT07807943
Phase 2Taking people
Cannabinoid Interactions With Central and Peripheral Pain Mechanisms in Osteoarthritis of the Knee
Where
Ann Arbor
Age
21 years to 75 years
People
200
Run by
Steven E Harte, PhD
See details and how to joinNCT04992624
No phaseTaking people
Patient Pain and Function in Medial Knee Osteoarthritis After Anteromedial vs Anterolateral Intra-Articular Corticosteroid Injection
Where
Bolingbrook, Chicago, La Grange, Orland Park, Woodridge
Age
40 years and over
People
140
Run by
University of Chicago
See details and how to joinNCT07804446
No phaseTaking people
Clinical Orthopaedic Data Bank (Acute and Chronic)
Where
Gainesville
People
10,000
Run by
University of Florida
See details and how to joinNCT00411060
Phase 4Taking people
Ketorolac in Upper Extremity Tendinopathy and Arthropathy
Where
Atlanta
Age
18 years and over
People
160
Run by
Emory University
See details and how to joinNCT05292339
No phaseEnrolling by invitation
LinkSymphoKnee (LSK) Total Knee Replacement System Study - Ultra-congruent (UC)
Where
Birmingham, Libertyville
Age
18 years to 79 years
People
600
Run by
LinkBio Corp.
See details and how to joinNCT06670651
No phaseTaking people
Impact of Bone-Marrow Aspirate Injections in Knee Arthroscopy
Where
New York
Age
18 years to 64 years
People
50
Run by
Hospital for Special Surgery, New York
See details and how to joinNCT06893302
No phaseTaking people
Perform Humeral System Study
Where
Columbus, Eagan, Lexington, Rochester, Salt Lake City, Sioux Falls, St Louis
Age
18 years and over
People
300 worldwide
Run by
Stryker Trauma and Extremities
See details and how to joinNCT05067543
Phase 1/2Taking people
Evaluation of Intra-articular CX-011 to Treat Moderate to Severe Pain From Knee Osteoarthritis
Where
Los Angeles
Age
40 years to 75 years
People
72
Run by
CarthroniX, Inc.
See details and how to joinNCT07308834
Phase 2Taking people
A Study to Assess Safety and Tolerability of PCRX-201 in Subjects With Painful Osteoarthritis of the Knee
Where
Altoona, Atlanta, Baltimore, Beverly Hills, Birmingham, Brooklyn, Charleston, Chicago, Chula Vista, Collierville, Columbia, Covina, Dallas, Dayton, Daytona Beach, Duncansville, Houston, Huntington Beach, Lake Charles, La Mesa, Las Vegas, Lewisville, Lincoln, Morehead City, New Orleans, New York, Oldsmar, Phoenix, Plantation, Rochester Hills, Santa Monica, Sarasota, West Hills, West Palm Beach, Whittier, Wilmington, Winter Park
Age
45 years to 80 years
People
135
Run by
Pacira Pharmaceuticals, Inc
See details and how to joinNCT06884865
No phaseEnrolling by invitation
MOON Onsite MRI 10 Years After ACL Reconstruction
Where
Cleveland
Age
22 years to 45 years
People
219
Run by
The Cleveland Clinic
See details and how to joinNCT04660955
No phaseTaking people
Bone Marrow Aspirate Concentrate (BMAC) vs Corticosteroid Injection
Where
Chicago
Age
18 years to 70 years
People
100
Run by
Rush University Medical Center
See details and how to joinNCT05985785
No phaseTaking people
A Prospective, Post-Market, Clinical Follow-up Study of the Incompass™ Total Ankle System
Where
Charleston, Eugene, Louisville, Morton Grove, South Bend
Age
21 years and over
People
200
Run by
Stryker Trauma and Extremities
See details and how to joinNCT07118501
No phaseTaking people
Prospective Case Series Evaluating 6-Month and 12-Month Outcomes After Cryoneurolysis for Chronic Pain
Where
Old Saybrook
Age
18 years and over
People
80
Run by
Yale University
See details and how to joinNCT07639060
No phaseNot yet taking people in United States
Evaluating the Effect of Adipose Tissue Processed With the SyntrFuge™ System for Knee Osteoarthritis
Where
Irvine
Age
18 years to 70 years
People
180
Run by
Syntr Health Technologies, Inc.
See details and how to joinNCT05526898
No phaseNot yet taking people in United States
Effects of Photobiomodulation on Inflammation and Chronic Pain in Knee Osteoarthritis (EPIC-KO)
Where
Gainesville
Age
50 years to 99 years
People
30
Run by
University of Florida
See details and how to joinNCT07079969
Phase 4Taking people
Novel Extended-Release Bupivacaine Polymer for Sustained Pain Relief Following Total Knee Arthroplasty
Where
Grosse Pointe Farms
Age
18 years and over
People
150
Run by
Henry Ford Health System
See details and how to joinNCT07775248
Phase 4Taking people
Systemic Oral Glucocorticoids for the Treatment of Acute Osteoarthritis Pain in the Emergency Department
Where
York
Age
18 years and over
People
192
Run by
WellSpan Health
See details and how to joinNCT06603662
Phase 2/3Taking people
Use of Corticosteroid in Intraopertive Injections in Total Knee Replacement Surgery.
Where
Bethesda
Age
18 years and over
People
240
Run by
Walter Reed National Military Medical Center
See details and how to joinNCT07151417
Phase 1Taking people
The Effect of Micro Fragmented Adipose Tissue (MFAT) on Shoulder Osteoarthritis
Where
Stanford
Age
25 years to 75 years
People
48
Run by
Stanford University
See details and how to joinNCT04929951
Phase 3Taking people
AMAZE 6: A Research Study Investigating How Well the Medicine NNC0487-0111 Helps People With Excess Body Weight and Knee Osteoarthritis Lose Weight and Reduce Pain
Where
Bellevue, Dallas, Escondido, Gurnee, Jacksonville, Lancaster, Louisville, Naples, Newport News, New York, Palm Springs, Portland, Skokie, Springfield, Statesville, Troy, Waterbury
Age
18 years and over
People
400 worldwide
Run by
Novo Nordisk A/S
See details and how to joinNCT07509307 · EU 2024-520445-23-00
No phaseTaking people
Diet Interventions: Remitted and Evaluated as Complementary Treatments for Pain
Where
Birmingham
Age
40 years to 75 years
People
200
Run by
University of Alabama at Birmingham
See details and how to joinNCT05785884
No phaseTaking people
Sleep TO Prevent Post-surgical Pain
Where
Baltimore, Chestnut Hill
Age
60 years and over
People
252
Run by
Johns Hopkins University
See details and how to joinNCT06976138
No phaseTaking people
A Multi-Center Study Assessing the Safety and Efficacy of the LEGION Medial Stabilized (MS) Insert in Patients Undergoing a Total Knee Arthroplasty (TKA)
Where
Charleston, Madison, Newton, New York
Age
18 years to 80 years
People
144
Run by
Smith & Nephew, Inc.
See details and how to joinNCT07199738
No phaseTaking people
Evaluating the Efficacy of a Mobile Application in Postoperative Rehabilitation
Where
New Haven
Age
18 years and over
People
100
Run by
Yale University
See details and how to joinNCT06407427