Osteoarthritis trials in United States

In United States 226 Also abroad 827

226 trials · From ClinicalTrials.gov, checked 13 November 2026. Ask the study team whether a trial fits you.

No phaseEnrolling by invitation
Network Modeling in Knee Osteoarthritis
Where
Herndon
Age
18 years to 99 years
People
200
Run by
George Mason University
See details and how to joinNCT07746284
No phaseEnrolling by invitation
Glenohumeral OsteoArthritis Therapy Trial
Where
Buffalo
Age
18 years and over
People
125
Run by
State University of New York at Buffalo
See details and how to joinNCT07744542
No phaseTaking people
Restoration of Thumb Strength and Function in Basal Joint Arthritis: A Comparative Effectiveness Trial (RESTART)
Where
Lebanon
Age
21 years and over
People
165
Run by
Dartmouth-Hitchcock Medical Center
See details and how to joinNCT04458584
No phaseTaking people
Innovations in Genicular Outcomes Registry
Where
Alexandria, Asheville, Baltimore, Bethesda, DeLand, DuBois, Garden City, Germantown, Irvine, Jersey City, Los Angeles, New Hartford, New Orleans, North Chelmsford, Omaha, Phoenix, Salt Lake City, State College, Tulsa
People
10,000
Run by
Pacira Pharmaceuticals, Inc
See details and how to joinNCT05495334
No phaseTaking people
The Osteoarthritis Prevention Study
Where
Boston, Chapel Hill, Winston-Salem
Age
50 years and over
People
1,230 worldwide
Run by
Wake Forest University
See details and how to joinNCT05946044
No phaseEnrolling by invitation
Journavx to Treat Pain After Thumb Basal Joint Arthroplasty
Where
Philadelphia
Age
40 years to 80 years
People
100
Run by
Rothman Institute Orthopaedics
See details and how to joinNCT07723352
Phase 2Taking people
Enhancing Modulation Effects of Baduanjin Through Neuromodulation for Knee OA
Where
Charlestown
Age
45 years to 75 years
People
140
Run by
Massachusetts General Hospital
See details and how to joinNCT05839535
Phase 1Not yet taking people in United States
Pilot and Feasibility Study of Anti-CD14 for the Treatment of Knee Osteoarthritis
Where
Philadelphia
Age
50 years to 80 years
People
40
Run by
VA Office of Research and Development
See details and how to joinNCT07481474
No phaseTaking people
MISHA Post-Market Clinical Study
Where
Charlottesville, Portland, Raleigh, Sonoma
Age
25 years to 65 years
People
120
Run by
Moximed
See details and how to joinNCT06118892
No phaseTaking people
MOTION Clinical Trial
Where
Chicago, Columbus, Davis, New York, Oak Brook, Oceanside, Omaha, Sacramento, San Antonio
People
100
Run by
Moximed
See details and how to joinNCT06843980
No phaseTaking people
Genicular Artery Embolization for Knee Osteoarthritis
Where
Chicago
Age
40 years to 80 years
People
15
Run by
Northwestern University
See details and how to joinNCT07537153
No phaseTaking people
Persona Revision Knee System Outcomes
Where
Bloomington, Chester, Cleveland, Columbia, Evansville, Fayetteville, Fresno, Granger, Lancaster, Little Rock, Louisville, Oregon City, Rochester, Southfield, Superior, Wauwatosa
Age
18 years and over
People
380
Run by
Zimmer Biomet
See details and how to joinNCT04821154
Phase 4Taking people
Magnesium-L-Threonate for Sleep Quality Post-Arthroplasty
Where
Miami
Age
18 years and over
People
64
Run by
University of Miami
See details and how to joinNCT06902285
Phase 3Taking people
A Research Study Investigating How Well the Medicine NNC0487-0111 Helps People With Excess Body Weight and Knee Osteoarthritis Lose Weight and Reduce Pain
Where
Bellevue, Blackfoot, Charlottesville, Conyers, Decatur, Hamden, Hollywood, Jacksonville, Las Vegas, Miami Lakes, Newport News, North Charleston, Phoenix, San Antonio, Walnut Creek, Waltham, Waterbury, Westfield, Wilmington
Age
18 years and over
People
400 worldwide
Run by
Novo Nordisk A/S
See details and how to joinNCT07481630 · EU 2024-520444-42-00
Phase 2Not yet taking people in United States
Inulin Supplementation for Reducing Inflammation and Knee Pain in Older Adults With Osteoarthritis
Where
West Haven
Age
40 years and over
People
84
Run by
Yale University
See details and how to joinNCT07189585
Early phase 1Taking people
A Randomized Pilot rTMS Trial for Knee Arthritis Pain and Depression
Where
Los Angeles
Age
50 years to 95 years
People
30
Run by
University of California, Los Angeles
See details and how to joinNCT06906939
No phaseTaking people
Rehabilitation Following Reverse Total Shoulder Arthroplasty
Where
Bloomington
Age
55 years and over
People
74
Run by
HealthPartners Institute
See details and how to joinNCT03804853
No phaseTaking people
MultiCenter IDE Study of the PEEK-OPTIMA™ Femoral Component vs a CoCr Alloy TKA Femoral Component of Similar Design
Where
Leawood, San Antonio
Age
18 years and over
People
200
Run by
Maxx Orthopedics Inc
See details and how to joinNCT06627673
No phaseTaking people
Gait Rehabilitation to Treat FastOA
Where
Chapel Hill
Age
16 years to 35 years
People
70
Run by
University of North Carolina, Chapel Hill
See details and how to joinNCT05848622
No phaseNot yet taking people in United States
Health Aid for Knee Osteoarthritis
Where
Austin
Age
18 years to 89 years
People
159
Run by
David Ring
See details and how to joinNCT07669532
No phaseTaking people
Effects of Movement Retraining on Knee Loading in Individuals With Knee Osteoarthritis
Where
Stanford
Age
18 years and over
People
31
Run by
Stanford University
See details and how to joinNCT06208631
No phaseNot yet taking people in United States
Synovial Fluid Withdrawal or PRP Injection For Acute ACL Tears and Cytokines
Where
Chicago
Age
18 years to 50 years
People
99
Run by
Rush University Medical Center
See details and how to joinNCT07142369
No phaseTaking people
Study of Wearable Interventions for Improving Mobility of Individuals With Knee Osteoarthritis
Where
Cambridge
Age
21 years to 100 years
People
9
Run by
Massachusetts Institute of Technology
See details and how to joinNCT07652437
No phaseTaking people
Fluoroscopic Versus Ultrasound Guidance for Cooled Radiofrequency Ablation of Geniculate Nerves in Knee Osteoarthritis: A Randomized Control Trial
Where
Rochester, Sacramento
Age
35 years to 99 years
People
90
Run by
University of California, Davis
See details and how to joinNCT04472702
Phase 2Not yet taking people in United States
Duloxetine and aeRobic Exercise to Improve Function in VEterans With Knee Osteoarthritis (DRIVE)
Where
Baltimore
Age
40 years and over
People
102
Run by
VA Office of Research and Development
See details and how to joinNCT07649291