Osteoarthritis trials in United States

In United States 226 Also abroad 827

226 trials · From ClinicalTrials.gov, checked 13 November 2026. Ask the study team whether a trial fits you.

Phase 4Taking people
Brain-Based and Clinical Phenotyping of Pain Pharmacotherapy in Knee Osteoarthritis
Where
Chicago
Age
41 years and over
People
180
Run by
Northwestern University
See details and how to joinNCT06245109
No phaseTaking people
Steps Towards Osteoarthritis Prevention
Where
Athens
Age
16 years to 40 years
People
56
Run by
University of Georgia
See details and how to joinNCT06193343
No phaseTaking people
A Prospective Total Joint Surgery Registry to Monitor Short- and Long-Term Clinical Outcomes
Where
Spokane
Age
18 years and over
People
10,000
Run by
Spokane Joint Replacement Center
See details and how to joinNCT06687109
No phaseTaking people
Zimmer Biomet Shoulder Arthroplasty PMCF
Where
Bloomington, Buffalo, Chicago, City of Saint Peters, Golden, Irvine, Jackson, Louisville, Murray, Philadelphia, Royal Oak, St Louis
Age
20 years and over
People
584 worldwide
Run by
Zimmer Biomet
See details and how to joinNCT04984291
Phase 4Taking people
Radiotherapy Compared to Corticosteroid Injection for Treatment of Hand Osteoarthritis
Where
Rochester
Age
50 years and over
People
165
Run by
Mayo Clinic
See details and how to joinNCT07217405
Phase 4Enrolling by invitation
Comparing Treatment of Knee Osteoarthritis With Triamcinolone Injections Using 40mg With Landmark Guidance and 20mg With Ultrasound Guidance
Where
Ventura
Age
50 years and over
People
140
Run by
Sosi Dzhugarian
See details and how to joinNCT07544576
Phase 1/2Taking people
CBD for Pain Following Orthopedic Shoulder Surgery
Where
Houston
Age
18 years and over
People
80
Run by
The Methodist Hospital Research Institute
See details and how to joinNCT06381791
No phaseNot yet taking people in United States
Psychosocial Interventions for Young Adults With Hip Pain
Where
Iowa City
Age
15 years to 39 years
People
150
Run by
Michael C Willey
See details and how to joinNCT04039386
Phase 2Taking people
Cannabidiol for Postoperative Opioid Reduction in Primary Total Knee Arthroplasty
Where
Ann Arbor, Detroit
Age
18 years to 80 years
People
380
Run by
Chad Brummett
See details and how to joinNCT06234631
No phaseTaking people
Move and Snooze: Adding Insomnia Treatment to an Exercise Program to Improve Pain Outcomes in Older Adults With Knee Osteoarthritis
Where
Ann Arbor
Age
50 years and over
People
288
Run by
University of Michigan
See details and how to joinNCT06580561
Phase 1/2Not yet taking people in United States
NANOVAE to Treat Knee Osteoarthritis (KOA)
Where
Chesterfield
Age
21 years to 75 years
People
24
Run by
Nova Vita Laboratory
See details and how to joinNCT06606561
Phase 1/2Not yet taking people in United States
The Safety and Efficacy of XytriX (Umbilical Cord-Derived Mesenchymal Stem Cells) in the Treatment of Knee Osteoarthritis
Where
Frisco
Age
18 years and over
People
75
Run by
TricelX Inc.
See details and how to joinNCT07487766
Phase 2Not yet taking people in United States
Long Duration High Frequency Ultrasound for the Treatment of Osteoarthritis
Where
Dryden, Stamford
Age
65 years to 85 years
People
240
Run by
ZetrOZ, Inc.
See details and how to joinNCT07515872
No phaseTaking people
Dose Response of Exercise for Arthritis Management
Where
Columbia
Age
18 years and over
People
285
Run by
University of South Carolina
See details and how to joinNCT06880653
No phaseTaking people
Cold and Compression Post TKA
Where
New Orleans
Age
50 years and over
People
90
Run by
Ochsner Health System
See details and how to joinNCT07023185
No phaseEnrolling by invitation
MDR Vivacit-E Elevated Study
Where
South Bend
Age
18 years and over
People
52
Run by
Zimmer Biomet
See details and how to joinNCT07150221
No phaseEnrolling by invitation
Tornier HRS (Humeral Reconstruction System) Study (REVIVE)
Where
Bradenton, Denver, Lexington, Tampa
Age
18 years and over
People
110
Run by
Stryker Trauma and Extremities
See details and how to joinNCT05500066
No phaseTaking people
The Effects of Patient and Visit Characteristics on Health Outcomes in Knee Osteoarthritis
Where
Sacramento
Age
50 years and over
People
220
Run by
University of California, Davis
See details and how to joinNCT06574191
No phaseTaking people
Focused Extracorporeal Shockwave Therapy for Knee Arthritis
Where
Cedar Knolls, West Orange
Age
30 years to 80 years
People
15
Run by
Kessler Foundation
See details and how to joinNCT05596591
No phaseTaking people
Mechanical Alignment vs Kalipered Kinematic Alignment Total Knee Arthroplasty
Where
Chicago
Age
21 years to 79 years
People
95
Run by
Northwestern University
See details and how to joinNCT06617871
No phaseTaking people
Evaluating Changes in Synovial Fluid Before and After GAE for Knee Osteoarthritis
Where
Aurora
Age
18 years and over
People
46
Run by
University of Colorado, Denver
See details and how to joinNCT06940479
No phaseTaking people
General vs Spinal in Total Joint Arthroplasty (TJA)
Where
Miami
Age
18 years and over
People
2,396
Run by
University of Miami
See details and how to joinNCT06747494
Phase 4Taking people
Knee Injections for Obese Patients With Knee Arthritis
Where
Jacksonville
Age
55 years to 85 years
People
40
Run by
Mayo Clinic
See details and how to joinNCT06782529
No phaseNot yet taking people in United States
Measurement of Osteoarthritic Patient Pain Through Electrodermal Activity Signals
Where
Lebanon
Age
50 years to 80 years
People
15
Run by
Dartmouth-Hitchcock Medical Center
See details and how to joinNCT06701461
Phase 2Taking people
The Effects of Tranexamic Acid on Joint Inflammation and Cartilage Health in Anterior Cruciate Ligament Injured Patients
Where
Stanford
Age
18 years to 30 years
People
50
Run by
Stanford University
See details and how to joinNCT03552705