Parkinson disease: open trials in Italy

76 open trials have a site in Italy. Registry data; only the trial team decides who can take part.

2026-526634-46-00
A Study to Evaluate the Efficacy and Safety of CP-012B in Participants With Parkinson’s Disease With Early Morning OFF Episodes
Trial Treatment · Phase 2 · Contera Pharma A/S
IRCCS Foundation Istituto Neurologico Carlo Besta, Milan · Asst Centro Specialistico Ortopedico Traumatologico Gaetano Pini Cto, Milan · Fondazione IRCCS Cà Granda Ospedale Maggiore Policlinico, Milan · Azienda Ospedaliera Universitaria - Universita degli Studi della Campania Luigi Vanvitelli, Naples · Fondazione Istituto Neurologico Nazionale Casimiro Mondino, Pavia · Irccs San Raffaele Roma S.r.l., Rome · Centro Ricerche Cliniche di Verona s.r.l., Verona
Registry updated 2026-11-06
NCT06341829
Visuospatial and Affective Abilities in Parkinson Disease
Trial Treatment · IRCCS Centro Neurolesi Bonino Pulejo
Laura Culicetto, Messina
Registry updated 2026-11-05
NCT07174310
A Study to Evaluate the Efficacy and Safety of Intravenous (IV) Prasinezumab in Participants With Early-Stage Parkinson's Disease
Trial Treatment · Phase 3 · Hoffmann-La Roche
Azienda Unita Sanitaria Locale Di Bologna, Bologna · Azienda Socio Sanitaria Territoriale degli Spedali Civili di Brescia, Brescia · Irccs San Raffaele Roma S.r.l., Cassino · Azienda Ospedaliero-Universitaria Policlinico G. Rodolico-San Marco Di Catania, Catania · IRCCS Ospedale Policlinico San Martino, Genoa · IRCCS Foundation Istituto Neurologico Carlo Besta, Milan · Asst Centro Specialistico Ortopedico Traumatologico Gaetano Pini Cto, Milan · Ospedale San Raffaele S.r.l., Milan · Azienda Ospedaliera Universitaria - Universita degli Studi della Campania Luigi Vanvitelli, Naples · Azienda Ospedaliera di Padova, Padova · Azienda Ospedaliero Universitaria Pisana, Pisa · Irccs San Raffaele Roma S.r.l., Rome · Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Rome · Azienda Ospedaliera Universitaria San Giovanni di Dio e Ruggi d'Aragona, Salerno
Registry updated 2026-11-05
NCT07066137
Motor Learning in Health and Movement Disorders: Role of Physical Activity and Advanced Devices
Trial Treatment · IRCCS Centro Neurolesi Bonino Pulejo
IRCCS Centro Neurolesi Bonino Pulejo, Messina
Registry updated 2026-11-03
NCT07906769
Automated Language Analysis in Neurodegenerative Diseases: Application of Artificial Intelligence Models
Trial Treatment · Istituti Clinici Scientifici Maugeri SpA
Istituti Clinici Scientifici Maugeri IRCCS Bari, Bari
Registry updated 2026-11-03
NCT06680830
A Phase 2 Study and Open-Label Extension of NEU-411 in Companion Diagnostic-Positive Participants With Early Parkinson's Disease
Trial Treatment · Phase 2 · Neuron23 Inc.
ASST Spedali Civili di Brescia, Brescia · AOU Policlinico-San Marco, Catania · Universita' Degli Studi G. D'Annunzio Di Chieti, Chieti Scalo · IRCCS - Ospedale San Raffaele, Milano · Azienda Ospedaliera Universitaria - Universita degli Studi della Campania Luigi Vanvitelli, Naples · Universita Degli Studi Di Padova, Padova · Ospedale Santa Chiara, Pisa · Istituto Neurologico Mediterraneo Neuromed S.p.A., Pozzilli · Irccs San Raffaele Roma S.r.l., Rome · Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Rome
Registry updated 2026-10-30
NCT07894900
Twenty-five Years of Advanced RadioTherapy at San Raffaele Hospital
Research · IRCCS San Raffaele
Department of Radiation Oncology, IRCCS San Raffaele Scientific Institute, Milan
Registry updated 2026-10-29
NCT07055087
Prevent Cognitive Decline in GBA-associated Parkinson's Disease
Trial Treatment · Phase 2 · University Hospital Tuebingen
University of Brescia and ASST Spedali Civili of Brescia, Brescia · Fondazione IRCCS Ca' Granda Policlinico Hospital, Milan · University of Pavia, Pavia
Registry updated 2026-10-23
NCT06976268
A Study to Determine if BHV-8000 is Effective, Safe and Tolerable as a Treatment for Adults Living With Early Parkinson's Disease
Trial Treatment · Phase 2/3 · Biohaven Therapeutics Ltd.
Azienda Socio Sanitaria Territoriale degli Spedali Civili di Brescia, Brescia · Azienda Ospedaliero-Universitaria Careggi, Florence · IRCCS Ospedale Policlinico San Martino, Genoa · Azienda Socio Sanitaria Territoriale Santi Paolo E Carlo, Milan · Ospedale San Raffaele S.r.l., Milan · Azienda Ospedaliero - Universitaria di Modena, Modena · Fondazione IRCCS San Gerardo dei Tintori, Monza · Azienda Ospedaliera Universitaria - Universita degli Studi della Campania Luigi Vanvitelli, Naples · Azienda Ospedaliera di Padova, Padova · Fondazione Istituto Neurologico Nazionale Casimiro Mondino, Pavia · Azienda Ospedaliero Universitaria Pisana, Pisa · Fondazione Policlinico Universitario Campus Bio-medico In Forma A Bbreviata Fon, Rome · Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Rome · Irccs San Raffaele Roma S.r.l., Rome · Azienda Ospedaliera Universitaria San Giovanni di Dio e Ruggi d'Aragona, Salerno
Registry updated 2026-10-22
NCT07781644
Study to Test Effects and Safety of RO7568282 in Early Parkinson's Disease
Trial Treatment · Phase 1/2 · Hoffmann-La Roche
Azienda Socio Sanitaria Territoriale degli Spedali Civili di Brescia, Brescia · Irccs San Raffaele Roma S.r.l., Cassino · Azienda Ospedaliero-Universitaria Policlinico G. Rodolico-San Marco Di Catania, Catania · Ospedale San Raffaele S.r.l., Milan · IRCCS Foundation Istituto Neurologico Carlo Besta, Milan · Azienda Ospedaliera Universitaria - Universita degli Studi della Campania Luigi Vanvitelli, Naples · Azienda Ospedaliera di Padova, Padova · Fondazione Istituto Neurologico Nazionale Casimiro Mondino, Pavia · Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Rome · Irccs San Raffaele Roma S.r.l., Rome · Azienda Ospedaliera Policlinico Universitario Tor Vergata, Rome · Azienda Ospedaliera Universitaria San Giovanni di Dio e Ruggi d'Aragona, Salerno
Registry updated 2026-10-20
NCT03545477
Assessment of the Rehabilitative Effects of Curved-walking Training in Stroke, Parkinson and Orthopaedic Populations
Trial Treatment · Istituti Clinici Scientifici Maugeri SpA
Istituti Clinici Scientifici Maugeri Spa, Scientific Institute of Lissone, Lissone
Registry updated 2026-10-15
NCT02071134
Registry of Deep Brain Stimulation With the VERCISE™ System: Vercise DBS Registry
Research · Boston Scientific Corporation
Villa Margherita, Arcugnano · Azienda Ospedaliero Universitaria di Ferrara, Ferrara · Ospedale dell'Angelo, Mestre · IRCCS Istituto Ortopedico Galeazzi, Milan · Fondazione Istituto Neurologico Casimiro Mondino, Pavia · Policlinico Universitario Agostino Gemelli, Rome · Osp. S. Maria Della Misericordia, Udine
Registry updated 2026-10-13
NCT07865260
PhiCube for Bilateral Upper Limb Neuromotor and Cognitive Rehabilitation in Adults
Trial Treatment · Istituto di Sistemi e Tecnologie Industriali Intelligenti per il Manifatturiero Avanzato
Istituti Clinici Scientifici Maugeri IRCCS Bari, Bari · Istituti Clinici Scientifici Maugeri IRCCS, Milano, Milan · Istituti Clinici Scientifici Maugeri IRCCS, Montescano, Montescano · Istituti Clinici Scientifici Maugeri IRCCS, Telese Terme, Telese Terme
Registry updated 2026-10-08
NCT03664609
Deep Brain Stimulation (DBS) Retrospective Outcomes Study
Research · Boston Scientific Corporation
Fondazione Istituto Neurologico Casimiro Mondino, Pavia
Registry updated 2026-10-07
NCT06891781
Investigating Adaptive Deep Brain Stimulation in Parkinson's Disease Management
Trial Treatment · Newronika
IRCCS San Gerardo dei Tintori, Monza
Registry updated 2026-09-24
NCT07833748
Integrated Motor-Cognitive Training in Parkinson's Disease: A Feasibility Study
Trial Treatment · University Hospital of Ferrara
Ferrara University Hospital, Ferrara
Registry updated 2026-09-22
NCT07827963
VisMemoPD Protocol: an Observational Pilot Study on Spatial and Topographical Memory in Patients With Parkinson's Disease and Parkinsonism
Research · IRCCS San Raffaele Roma
IRCCS San Raffaele Cassino - CTC Via G. di Biasio, 1, Cassino · University of Roma La Sapienza Department of Psychology University of Rome, Roma · University of Roma La Sapienza Department of Psychology University of Rome 00185, Rome, Roma
Registry updated 2026-09-18
NCT07794072
Digital Patient Engagement in Technology-Supported Neurorehabilitation
Research · Catholic University, Italy
ICS Maugeri IRCCS - Istituto Scientifico di Milano, Milan · ICS Maugeri IRCCS - Istituto Scientifico di Montescano, Montescano · ICS Maugeri IRCCS - Istituto Scientifico di Pavia, Pavia
Registry updated 2026-09-15
NCT07514858
A Trial Investigating Lu AF28996 in Adults With Parkinson's Disease Who Have Motor Fluctuations
Trial Treatment · Phase 2 · H. Lundbeck A/S
Azienda Socio Sanitaria Territoriale degli Spedali Civili di Brescia, Brescia · Azienda Ospedaliera Universitaria - Universita degli Studi della Campania Luigi Vanvitelli, Naples · Azienda Ospedaliera di Padova, Padova · Irccs San Raffaele Roma S.r.l., Rome · Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Rome
Registry updated 2026-09-08
NCT06339398
To Evaluate the Dose-response Effects of a Defined Volume of Physical Exercise on the Change of Peripheral Biomarkers, Clinical Response and Brain Connectivity in Parkinson's Disease: a Prospective, Observational, Cohort Pilot Study
Research · Casa di Cura San Raffaele Cassino
San Raffaele Cassino, Cassino
Registry updated 2026-09-02
NCT06596746
Neurodegenerative Diseases Progression Markers (MARKERS-NDD)
Research · Casa di Cura San Raffaele Cassino
San Raffaele Cassino, Cassino
Registry updated 2026-09-02
NCT07761936
Safinamide vs Placebo for Pain in Patients With Parkinson's Disease and Motor Fluctuations
Trial Treatment · Phase 3 · Universita di Verona
Azienda Ospedaliera Universitaria Integrata Verona, Verona
Registry updated 2026-08-13
NCT07097103
Parkinson's Research In Metagenomic Early Stage Biomarkers
Trial Treatment · IRCCS San Raffaele Roma
Casa di Cura San Raffale Cassino, Cassino · IRCCS San Raffale Roma, Rome
Registry updated 2026-07-30
NCT07716553
Study of Transanal Irrigation vs Standard Care for Constipation, Gut Microbiota, and Motor Disorders in Parkinson's Disease
Trial Treatment · University Hospital of Ferrara
University Hospital Ferrara, Ferrara
Registry updated 2026-07-30
NCT04477785
PPMI Clinical - Establishing a Deeply Phenotyped PD Cohort
Research · Michael J. Fox Foundation for Parkinson's Research
University of Salerno, Salerno
Registry updated 2026-07-27

All Parkinson disease trials and the map

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