Prostate cancer trials in United States

In United States 658 Also abroad 1481

658 trials · From ClinicalTrials.gov, checked 11 November 2026. Ask the study team whether a trial fits you.

Phase 2Taking people
At-Home Cancer Directed Therapy Versus in Clinic for the Treatment of Patients With Advanced Cancer
Where
Grand Forks, Jacksonville
Age
18 years and over
People
220
Run by
Mayo Clinic
See details and how to joinNCT05969860
No phaseTaking people
ARCTIC: Liquid Biomarkers in the Prospective Androgen Receptor Signaling Inhibitors (ARSI) Resistance Clinical Trials
Where
Durham, Madison, New York
Age
18 years and over
People
120
Run by
Duke University
See details and how to joinNCT06141993
No phaseTaking people
The Vanguard Study: Testing a New Way to Screen for Cancer
Where
Bethesda, Brownstown, Chapel Hill, Charlottesville, Chesterfield, Cheyenne Wells, Cleveland, Clinton Township, Dearborn, Denver, Detroit, Durham, Fairfax, Fort Collins, Greeley, Grosse Pointe Farms, Honolulu, Kansas City, Lafayette, Livonia, Lone Tree, Loveland, Milwaukee, Minneapolis, Norfolk, Novi, Oklahoma City, Pleasanton, Plymouth, Portsmouth, Richmond, Royal Oak, San Diego, South Hill, Springfield, Sterling Heights, St Louis, Tacoma, Troy, West Bloomfield, Wyandotte
Age
45 years to 75 years
People
24,000
Run by
National Cancer Institute (NCI)
See details and how to joinNCT06995898
Phase 2Taking people
Evaluating In Home Cancer Therapy Versus In Clinic Cancer Therapy in Black Men With Locally Advanced, Biochemically Recurrent and Metastatic Prostate Cancer
Where
Jacksonville
Age
18 years and over
People
38
Run by
Mayo Clinic
See details and how to joinNCT07073794
Phase 1Taking people
Robot-Assisted Prostate Biopsy With a Novel Ultrasound Probe
Where
Baltimore
Age
40 years to 75 years
People
60
Run by
Johns Hopkins University
See details and how to joinNCT07271017
Phase 2Taking people
A Study to Test Inavolisib Treatment in Participants With Metastatic Castration-Resistant Prostate Cancer
Where
Aurora, Iowa City, Los Angeles, Myrtle Beach, Providence, San Francisco, The Bronx
Age
18 years and over
People
100 worldwide
Run by
Hoffmann-La Roche
See details and how to joinNCT07287150 · EU 2025-521327-67-00
No phaseTaking people
WATER IV PCa (AS Sub-study)
Where
Albany, Alexandria, Atlanta, Austin, Baltimore, Boulder, Chandler, Charleston, Chicago, Cleveland, Dallas, Delray Beach, Glenview, Hackensack, Idaho Falls, Kearney, Los Angeles, Miami, Murrells Inlet, Murrieta, New York, North Kansas City, Omaha, Rochester, Sheboygan, Tampa
Age
45 years and over
People
333 worldwide
Run by
PROCEPT BioRobotics
See details and how to joinNCT07650448
No phaseTaking people
Rehabilitation and Sex Therapy to Optimize Recovery After Prostate Cancer Treatment
Where
Durham
Age
18 years and over
People
30
Run by
Duke University
See details and how to joinNCT07685249
No phaseNot yet taking people in United States
Remote Screening and Navigation to Increase Trial Enrollment, INVITE Trial
Where
Seattle
Age
18 years and over
People
50
Run by
Fred Hutchinson Cancer Center
See details and how to joinNCT07908407
No phaseTaking people
A Multilevel Approach to Connecting Underrepresented Populations to Clinical Trials
Where
Gainesville, Jacksonville, Miami
Age
18 years to 100 years
People
350
Run by
University of Florida
See details and how to joinNCT05655494
Phase 3Taking people
Study of Opevesostat (MK-5684) Versus Alternative NHA in mCRPC (MK-5684-003)
Where
Aberdeen, Aurora, Austin, Baltimore, Charleston, Charlottesville, Chicago, Cleveland, Dallas, Detroit, Fort Myers, Hattiesburg, Highlands Ranch, Houston, Iowa City, Lakewood, Las Vegas, Lexington, Lone Tree, Marshall, Miami, Milwaukee, Minneapolis, Mitchell, Morristown, Nashville, New Brunswick, New Haven, New Orleans, Omaha, Orange, Palo Alto, Pierre, Pittsburgh, Portland, Richmond, Riverside, Roanoke, Saint Louis Park, Seattle, Sioux Falls, St Louis, The Bronx, Yankton
Age
18 years and over
People
1,310 worldwide
Run by
Merck Sharp & Dohme LLC
See details and how to joinNCT06136624 · EU 2023-504899-25-00
Phase 3Taking people
A Study of Changes to Prostate Procedures
Where
Basking Ridge, Commack, Harrison, Middletown, Montvale, New York, Uniondale
Age
18 years and over
People
800
Run by
Memorial Sloan Kettering Cancer Center
See details and how to joinNCT06986083
Phase 1/2Taking people
A Study Evaluating the Safety, Pharmacokinetics, and Preliminary Activity of GDC-1261 in Participants With Advanced or Metastatic Prostate Cancer
Where
Nashville, New Haven, Scottsdale
Age
18 years and over
People
260 worldwide
Run by
Genentech, Inc.
See details and how to joinNCT07567846
Phase 4Taking people
Impact of Fluciclovine (18F) PET (Positron Emission Tomography) on the Management of Prostate Cancer Following Negative or Equivocal PSMA (Prostate-Specific Membrane Antigen) PET Imaging at the Time of Biochemical Recurrence
Where
Atlanta, Austin, Boston, Portland, San Diego, St Louis
Age
18 years and over
People
142
Run by
Blue Earth Diagnostics
See details and how to joinNCT07569926
Phase 2Taking people
Study of Oral MRT-2359 With Apalutamide in Prostate Cancer
Where
Baltimore, Charlotte, Colorado Springs, East Brunswick, Fairfax, Kansas City, Lancaster, Los Angeles, Nashville, Newport Beach, Novi, Omaha, Seattle, West Valley City
Age
18 years and over
People
25
Run by
Monte Rosa Therapeutics, Inc
See details and how to joinNCT07745361
Phase 2Taking people
Testing the Effectiveness of Two Immunotherapy Drugs (Nivolumab and Ipilimumab) With One Anti-cancer Targeted Drug (Cabozantinib) for Rare Genitourinary Tumors
Where
Aberdeen, Aitkin, Alcoa, Allentown, Alton, Ames, Anaconda, Anchorage, Ankeny, Ann Arbor, Arroyo Grande, Ashland, Atlanta, Aurora, Aventura, Baker City, Ballwin, Baltimore, Bardstown, Basking Ridge, Baton Rouge, Beavercreek, Bellevue, Bellingham, Belpre, Bend, Bethesda, Bethlehem, Bettendorf, Billings, Birmingham, Bloomington, Boardman, Boise, Bolivar, Bonne Terre, Boone, Bozeman, Brainerd, Branson, Brighton, Brooklyn, Brownstown, Bryan, Buffalo, Burbank, Burien, Burlington, Burnsville, Burr Ridge, Caldwell, Cambridge, Canton, Cape Girardeau, Carbondale, Caro, Carson City, Carterville, Carthage, Centerville, Centralia, Chanute, Chapel Hill, Charleston, Chelsea, Chicago, Chillicothe, Cincinnati, City of Saint Peters, Clackamas, Clarkston, Clinton Township, Clive, Clovis, Cody, Coeur d'Alene, Colorado Springs, Columbus, Commack, Coon Rapids, Coos Bay, Corbin, Council Bluffs, Covington, Creston, Creve Coeur, Cudahy, Dallas, Danville, Dayton, Dearborn, Decatur, Deer River, Delaware, Denver, Des Moines, Detroit, Detroit Lakes, Dixon, Dodge City, Dublin, Duluth, Durango, East China Township, East Stroudsburg, Eau Claire, Edina, Edmonds, Effingham, El Dorado, Emeryville, Emmett, Enumclaw, Erie, Eureka, Everett, Fairway, Fargo, Farmington, Federal Way, Fergus Falls, Findlay, Flint, Fort Dodge, Fort Lauderdale, Fort Smith, Fort Worth, Fosston, Franklin, Frederick, Fridley, Fruitland, Gahanna, Galesburg, Garden City, Germantown, Grafton, Grand Island, Great Bend, Great Falls, Green Bay, Greenbrae, Greensburg, Greenville, Grosse Pointe Woods, Grove City, Harrison, Hays, Hazleton, Helena, Henderson, Hendersonville, Hibbing, Homer Glen, Hot Springs, Independence, Iowa City, Issaquah, Jackson, Jamestown, Jefferson, Jefferson City, Jefferson Hills, Johns Creek, Joplin, Kalispell, Kansas City, Kearney, Kenner, Kennewick, Kenosha, Kettering, Kewanee, Kingman, Knoxville, Lacey, Lake Forest, Lake Success, Lakewood, Lancaster, Lansing, Las Vegas, Lawrence, Lawton, Lee's Summit, Lexington, Liberal, Lima, Lincoln, Littleton, Livonia, London, Longmont, Longview, Los Angeles, Louisville, Macomb, Manhattan, Mansfield, Maple Grove, Maplewood, Marietta, Marinette, Marion, Marlette, Marshalltown, Marshfield, Martinez, Marysville, Mattoon, Maywood, McPherson, Melrose Park, Meridian, Metairie, Miami Beach, Middletown, Milwaukee, Mineola, Minneapolis, Minocqua, Missoula, Monroeville, Monticello, Montvale, Mount Vernon, Mukwonago, Nampa, Nashville, Natrona Heights, Newark, Newberg, New Lenox, New Orleans, Newport Beach, New Richmond, Newton, New Ulm, New York, N. Huntingdon, Novi, Oakland, Oak Park, Oconomowoc, O'Fallon, Oklahoma City, Olathe, Omaha, Ontario, Oregon City, Orlando, Orland Park, Oshkosh, Ottawa, Pahrump, Papillion, Parker, Park Rapids, Parsons, Peabody, Pekin, Peoria, Perrysburg, Peru, Phoenix, Pittsburg, Pittsburgh, Pontiac, Port Huron, Portland, Portsmouth, Post Falls, Poulsbo, Pratt, Princeton, Pueblo, Racine, Redmond, Reno, Renton, Rice Lake, Richardson, Richmond, Robbinsdale, Rochester, Rochester Hills, Rolla, Saginaw, Sainte Genevieve, Saint Joseph, Saint Louis Park, Saint Paul, Salina, Sandpoint, Sandstone, San Luis Obispo, Santa Maria, Scottsdale, Seattle, Sedro-Woolley, Shakopee, Sheboygan, Shelby, Shelton, Shepherdsville, Sheridan, Shiloh, Silverdale, Springfield, Sterling Heights, Stevens Point, Stillwater, St Louis, Sullivan, Summit, Swansea, Syracuse, Tacoma, Tawas City, Toledo, Topeka, Troy, Tucson, Tulsa, Twin Falls, Two Rivers, Uniondale, Urbana, Vancouver, Virginia, Waconia, Walla Walla, Walnut Creek, Warren, Washington, Washington D.C., Waukee, Waukesha, Wauwatosa, Wellington, West Allis, West Bloomfield, West Branch, West Chester, West Des Moines, Westerville, Weston, Westwood, Wexford, Wichita, Willmar, Winchester, Winfield, Woodbury, Wyandotte, Wyoming, Yakima, Yelm, Yorkville, Youngstown, Ypsilanti, Zanesville
Age
18 years and over
People
314 worldwide
Run by
National Cancer Institute (NCI)
See details and how to joinNCT03866382
Phase 1/2Taking people
A Trial to Find Out if REGN5678 (Nezastomig) is Safe and How Well it Works Alone or in Combination With Cemiplimab for Adult Participants With Metastatic Castration-Resistant Prostate Cancer and Other Tumors
Where
Boston, Charlottesville, Columbus, Denver, Detroit, Gilbert, Houston, Jacksonville, Morgantown, New Haven, New York, Philadelphia, Phoenix, Portland, Providence, Rochester, Santa Monica, Tampa, Tucson
Age
18 years and over
People
345 worldwide
Run by
Regeneron Pharmaceuticals
See details and how to joinNCT03972657
No phaseTaking people
Collecting Blood Samples From Patients With and Without Cancer to Evaluate Tests for Early Cancer Detection
Where
Aberdeen, Aitkin, Akron, Albert Lea, Albuquerque, Allentown, Alma, Alpena, Alton, Amarillo, Ames, Anaconda, Anchorage, Anderson, Ankeny, Ann Arbor, Antigo, Appleton, Arroyo Grande, Asheville, Ashland, Augusta, Aurora, Aventura, Baker City, Bakersfield, Ballwin, Baltimore, Baraboo, Barberton, Bardstown, Barrington, Baton Rouge, Battle Creek, Baxter, Beavercreek, Belfast, Bellingham, Belpre, Bemidji, Bend, Berlin, Bethesda, Bethlehem, Biddeford, Billings, Bismarck, Bloomington, Boardman, Boise, Bolivar, Bonita Springs, Boone, Boulder, Bozeman, Brainerd, Branson, Braselton, Brewer, Brighton, Brownstown, Brunswick, Bryan, Burbank, Burien, Burlington, Burnsville, Caldwell, Cambridge, Canton, Cape Girardeau, Carbondale, Carmichael, Caro, Carson City, Carterville, Carthage, Cary, Cedar Rapids, Centennial, Centerville, Centralia, Chaska, Chelsea, Chesapeake, Chesterfield, Cheyenne, Chicago, Chillicothe, Cincinnati, Clackamas, Clarkston, Clearwater, Clinton, Clinton Township, Clive, Clyde, Cody, Coeur d'Alene, Colorado Springs, Columbia, Columbus, Concord, Coon Rapids, Coos Bay, Corbin, Council Bluffs, Creston, Crosslake, Crystal Lake, Cudahy, Danville, Dayton, Dearborn, Decatur, Deerfield Beach, Deer River, Delaware, Denver, Des Moines, Detroit, Detroit Lakes, Dixon, Downers Grove, Dublin, Duluth, Durango, Durham, East China Township, Easton, East Stroudsburg, Eau Claire, Edgewood, Edina, Edmonds, Effingham, Elgin, Elk Grove, Elmhurst, Elmira, Ely, Emeryville, Emmett, Englewood, Enumclaw, Eureka, Everett, Evergreen Park, Fairbanks, Fargo, Farmington, Farmington Hills, Federal Way, Findlay, Fishersville, Flint, Florence, Fond du Lac, Fort Collins, Fort Dodge, Fort Lauderdale, Fort Myers, Fort Smith, Fort Thomas, Fosston, Franklin, Freehold, Fridley, Fruitland, Gaffney, Gahanna, Gainesville, Galesburg, Garden City, Garner, Georgetown, Germantown, Gladwin, Glen Burnie, Glens Falls, Goldsboro, Grafton, Grand Forks, Grand Island, Grand Rapids, Great Bend, Great Falls, Greeley, Green Bay, Greenville, Greenwood, Greer, Grosse Pointe Woods, Grove City, Hackettstown, Harvey, Havre, Hayward, Hazel Crest, Hazleton, Helena, Henderson, Hendersonville, Hibbing, Hood River, Houma, Houston, Huntington, International Falls, Issaquah, Jackson, Jacksonville, Jamaica, Jamaica Plain, Jamestown, Janesville, Jefferson, Jefferson City, Joplin, Kalamazoo, Kalispell, Kansas City, Kearney, Kennewick, Kenosha, Kettering, Kewanee, Kingman, Lacey, La Crosse, Lakeland, Lakewood, Lancaster, Lansing, Laredo, Las Cruces, Las Vegas, Leavenworth, Lewisburg, Lexington, Libertyville, Lima, Lincoln, Little Rock, Littleton, Livonia, Loma Linda, London, Lone Tree, Long Beach, Longmont, Longview, Loveland, Macomb, Madison, Manchester, Mankato, Mansfield, Maple Grove, Maplewood, Marietta, Marinette, Marion, Marlette, Marrero, Marshalltown, Martinez, Marysville, Mattoon, Meadowbrook, Mechanicsville, Medford, Medina, Merced, Meridian, Metairie, Miami Beach, Midland, Midlothian, Milwaukee, Minneapolis, Minot, Missoula, Moline, Monticello, Moose Lake, Morristown, Mount Pleasant, Mount Sterling, Mount Vernon, Mukwonago, Mullica Hill, Murrells Inlet, Muskegon, Nags Head, Nampa, Napa, Neenah, New Albany, Newark, Newberg, New Brunswick, New London, New Orleans, New Richmond, Newton, New Ulm, New York, Niles, Norfolk, Normal, Norton Shores, Novi, Oakland, Oak Lawn, Ocean Pines, Oconomowoc, Oconto Falls, O'Fallon, Oklahoma City, Olney, Omaha, Ontario, Oregon City, Osage Beach, Oshkosh, Ottawa, Paducah, Pahrump, Papillion, Parker, Park Rapids, Park Ridge, Pekin, Pennington, Peoria, Pequot Lakes, Perrysburg, Peru, Phoenix, Phoenixville, Pine River, Pittsburg, Plant City, Pompton, Pontiac, Portland, Portsmouth, Port Townsend, Post Falls, Pottstown, Princeton, Providence, Pueblo, Racine, Raleigh, Rancho Mirage, Randallstown, Reading, Redmond, Reed City, Reno, Renton, Rhinelander, Richmond, Rio Rancho, Robbinsdale, Rockford, Rocklin, Rockport, Rolla, Royal Oak, Sacramento, Safety Harbor, Saginaw, Saint Cloud, Sainte Genevieve, Saint Joseph, Saint Louis Park, Saint Paul, Salisbury, San Antonio, Sandpoint, Sandstone, Sanford, San Luis Obispo, Santa Cruz, Santa Maria, Santa Rosa, Savannah, Scarborough, Seattle, Sedro-Woolley, Shakopee, Shawano, Sheboygan, Shelton, Sheridan, Silverdale, Sioux Falls, Southfield, South Portland, Spartanburg, Spokane, Spooner, Springfield, Staples, Sterling Heights, Stevens Point, St. Helena, Stillwater, St Louis, Stockton, Stony Brook, St. Petersburg, Sturgeon Bay, Sullivan, Summit, Superior, Tacoma, Tampa, Tawas City, Thief River Falls, Thornton, Tifton, Toledo, Topeka, Towson, Traverse City, Troy, Twin Falls, Two Rivers, Union, Urbana, Vancouver, Vineland, Virginia, Virginia Beach, Waconia, Walla Walla, Walnut Creek, Warren, Warwick, Washington, Washington D.C., Waukee, Waukesha, Waupaca, Wausau, Wauwatosa, Weaverville, West Allis, West Bloomfield, West Branch, West Columbia, West Des Moines, Westerville, West Haven, Westminster, West Reading, Wichita, Wilkes-Barre, Willmar, Wilmington, Winter Haven, Wisconsin Rapids, Woodbury, Woodland, Worthington, Wyandotte, Wyoming, Yakima, Yelm, Yorkville, Youngstown, Ypsilanti, Zanesville
Age
40 years to 75 years
People
2,900
Run by
Alliance for Clinical Trials in Oncology
See details and how to joinNCT05334069
No phaseTaking people
cfDNA Assay Prospective Observational Validation for Early Cancer Detection and Minimal Residual Disease
Where
Austin, Charleston, Cleveland, Corbin, Duarte, Elizabethtown, Florence, Gainesville, Lexington, Memphis, Miami, Minneapolis, Nashville, New Albany, Paducah, Portland, Rochester
Age
40 years and over
People
7,000
Run by
Adela, Inc
See details and how to joinNCT05366881
No phaseTaking people
Evaluating Safety and Efficacy of Prostate-sparing Radical Cystectomy
Where
Baltimore, Washington D.C.
Age
18 years and over
People
70
Run by
Johns Hopkins University
See details and how to joinNCT05792722
Phase 1Taking people
A Study of LY4052031 in Participants With Advanced or Metastatic Urothelial Cancer or Other Solid Tumors
Where
Atlanta, Boston, Chicago, Cleveland, Denver, Duarte, Grand Rapids, Houston, Indianapolis, La Jolla, Los Angeles, Nashville, New York, Salt Lake City, San Antonio, St Louis, St. Petersburg, West Valley City
Age
18 years and over
People
460 worldwide
Run by
Eli Lilly and Company
See details and how to joinNCT06465069 · EU 2024-512927-36-00
Phase 1Not yet taking people in United States
A Study of 177Lu-DTPA-SC16.56 in People With Neuroendocrine Carcinomas of the Lung and Prostate
Where
Basking Ridge, Commack, Harrison, Middletown, Montvale, New York, Rockville Centre
Age
18 years and over
People
12
Run by
Memorial Sloan Kettering Cancer Center
See details and how to joinNCT06941480
No phaseTaking people
Distance-Based Exercise to Preserve Function and Prevent Disability
Where
Boston, Butler, Cranberry Township, Dublin, Fremont, Fresno, Indiana, Kernersville, Mechanicsville, Midlothian, Modesto, Mount Airy, New Castle, Oakland, Pittsburgh, Richmond, Sacramento, San Francisco, San Jose, San Rafael, Santa Clara, Santa Rosa, Seneca, Vallejo, Walnut Creek, Winston-Salem
Age
18 years and over
People
104
Run by
Alliance for Clinical Trials in Oncology
See details and how to joinNCT07059884
Phase 1Taking people
A Study of LY4257496 in Participants With Cancer (OMNIRAY)
Where
Atlanta, Boston, Dallas, Detroit, Duarte, Grand Rapids, Houston, Miami, New York, Pittsburgh, Santa Monica, Stanford, St Louis, Tampa
Age
18 years and over
People
421 worldwide
Run by
Eli Lilly and Company
See details and how to joinNCT07114601 · EU 2025-522367-15-00
No phaseTaking people
Validation of a Platelet Proteomic Assay for Diagnosing and Monitoring Prostate Cancer
Where
Durham
Age
40 years and over
People
300
Run by
Duke University
See details and how to joinNCT07144228