Sarcoma trials in United States

In United States 300 Also abroad 605

300 trials · From ClinicalTrials.gov, checked 11 November 2026. Ask the study team whether a trial fits you.

Phase 1Taking people
Safety and Feasibility of Intraoperative Visualization With Cytalux in Children
Where
Chicago
Age
6 years to 17 years
People
10
Run by
Ann & Robert H Lurie Children's Hospital of Chicago
See details and how to joinNCT06235125
Phase 2Taking people
Study of Magnetic Resonance Image and Computed Tomography-Guided Stereotactic Body Radiation Therapy for Abdominopelvic Sarcomas (MARS Trial)
Where
Los Angeles
Age
12 years and over
People
20
Run by
Jonsson Comprehensive Cancer Center
See details and how to joinNCT06436612
Phase 1Taking people
Zanzalintinib Combined With Eribulin in Advanced Liposarcoma and Leiomyosarcoma
Where
St Louis
Age
18 years and over
People
18
Run by
Washington University School of Medicine
See details and how to joinNCT06957431
No phaseTaking people
Intravital Microscopy in Human Solid Tumors
Where
Jacksonville
Age
18 years and over
People
85
Run by
Mayo Clinic
See details and how to joinNCT03823144
No phaseTaking people
Collecting Blood and Tissue Sample Donations for Research for HIV/AIDS-Related Cancers
Where
Baltimore, La Jolla, Miami, New York, Salt Lake City, San Francisco, Washington D.C.
Age
18 years and over
People
200
Run by
AIDS Malignancy Consortium
See details and how to joinNCT05663502
Phase 1/2Taking people
A Study to Evaluate the Safety, Tolerability, and Efficacy of BMS-986523 Alone and in Combination With Anti-Cancer Agents in Participants With Advanced Solid Malignancies
Where
Baltimore, Fairfax, San Antonio, West Valley City
Age
18 years and over
People
252 worldwide
Run by
Bristol-Myers Squibb
See details and how to joinNCT07223047
Phase 1/2Taking people
A Study of Repotrectinib (TPX-0005) in Patients With Advanced Solid Tumors Harboring ALK, ROS1, or NTRK1-3 Rearrangements
Where
Ann Arbor, Appleton, Athens, Aurora, Baltimore, Bolivar, Boston, Canton, Chicago, Cincinnati, Cleveland, Columbus, Dallas, Detroit, Duarte, Fairfax, Glendale, Goldsboro, Hollywood, Houston, Kingwood, La Jolla, Long Beach, Memphis, New Brunswick, New Orleans, New York, Orange, Peoria, Philadelphia, Saint Paul, Santa Rosa, Seattle, St Louis, Tacoma, Tampa, Toledo, Washington D.C.
Age
12 years and over
People
500 worldwide
Run by
Turning Point Therapeutics, Inc.
See details and how to joinNCT03093116 · EU 2024-512606-25-00
Phase 1Taking people
Palbociclib and Pembrolizumab in Sarcoma
Where
Iowa City
Age
12 years and over
People
8
Run by
John Rieth
See details and how to joinNCT06113809
Phase 2Taking people
SATURN-STS: Phase II Study of Neoadjuvant Atezolizumab With Doxorubicin, Concurrent Atezolizumab With Pre-operative Radiation Therapy and Adjuvant Atezolizumab in Patients With High-risk Surgically Resectable Extremity and Truncal Soft Tissue Sarcoma
Where
Houston
Age
18 years and over
People
50
Run by
M.D. Anderson Cancer Center
See details and how to joinNCT07049848
Phase 2Taking people
Ph 2 Elacestrant in ER Positive Uterine Sarcomas
Where
Boston
Age
18 years and over
People
30
Run by
Dana-Farber Cancer Institute
See details and how to joinNCT07467772
Phase 1Taking people
B7-H3-Specific Chimeric Antigen Receptor Autologous T-Cell Therapy for Pediatric Patients With Solid Tumors (3CAR)
Where
Memphis
Age
Up to 21 years
People
48
Run by
St. Jude Children's Research Hospital
See details and how to joinNCT04897321
Phase 1/2Taking people
Study of Onivyde With Talazoparib or Temozolomide in Children With Recurrent Solid Tumors and Ewing Sarcoma
Where
Atlanta, Aurora, Houston, Memphis, Minneapolis, Palo Alto, Washington D.C.
Age
12 months to 30 years
People
90 worldwide
Run by
St. Jude Children's Research Hospital
See details and how to joinNCT04901702
No phaseTaking people
Effects of Dexrazoxane Hydrochloride on Biomarkers Associated With Cardiomyopathy and Heart Failure After Cancer Treatment
Where
Akron, Albuquerque, Asheville, Atlanta, Baltimore, Birmingham, Boston, Buffalo, Burlington, Charleston, Chicago, Cincinnati, Columbia, Dallas, Detroit, Duarte, Flint, Fort Myers, Fort Worth, Gainesville, Greenville, Hackensack, Hollywood, Honolulu, Houston, Jackson, Jacksonville, Las Vegas, Lebanon, Little Rock, Madera, Milwaukee, New Haven, New Hyde Park, New Orleans, Oakland, Oak Lawn, Oklahoma City, Orlando, Palo Alto, Peoria, Philadelphia, Phoenix, Portland, Providence, Richmond, Rochester, San Antonio, San Diego, Scarborough, Seattle, Spokane, St Louis, Stony Brook, St. Petersburg, Syracuse, Tampa, Tucson, West Palm Beach, Winston-Salem
People
420 worldwide
Run by
Children's Oncology Group
See details and how to joinNCT01790152
No phaseTaking people
Study Assessing the Effects of Early Psychiatric Referral on Mental Health and Quality of Life in People With Sarcoma
Where
Basking Ridge, Commack, Fort Bliss, Harrison, Middletown, Montvale, New York, Uniondale
Age
18 years and over
People
60
Run by
Memorial Sloan Kettering Cancer Center
See details and how to joinNCT06129903
Phase 1/2Taking people
DFMO Maintenance for Patients With Relapsed/Refractory Ewing Sarcoma or Osteosarcoma
Where
The Bronx
Age
Up to 39 years
People
15
Run by
Montefiore Medical Center
See details and how to joinNCT06892678
No phaseTaking people
An Organoid-based Functional Precision Medicine Trial in Osteosarcoma
Where
Los Angeles
People
40
Run by
Jonsson Comprehensive Cancer Center
See details and how to joinNCT06064682
Phase 1Taking people
Autologous B7-H3 Chimeric Antigen Receptor T Cells in Relapsed/Refractory Solid Tumors
Where
Palo Alto
Age
2 years to 30 years
People
41
Run by
Stanford University
See details and how to joinNCT06500819
Phase 2Taking people
I-SPY TRIAL: Neoadjuvant and Personalized Adaptive Novel Agents to Treat Breast Cancer
Where
Atlanta, Aurora, Birmingham, Buffalo, Chicago, Cleveland, Columbus, Dallas, Davis, Duarte, Falls Church, Houston, La Jolla, Lansing, Los Angeles, Maywood, Minneapolis, Nashville, New Brunswick, New Haven, Newport Beach, New York, Philadelphia, Pittsburgh, Portland, Rochester, Saint Louis Park, Salt Lake City, San Francisco, Scottsdale, Seattle, Sioux Falls, Tampa, The Bronx, Tucson, Washington D.C., Westwood, Winston-Salem
Age
18 years and over
People
5,000
Run by
QuantumLeap Healthcare Collaborative
See details and how to joinNCT01042379
Phase 1Taking people
Safety, Pharmacokinetics, and Clinical Activity of LP-284 in Adult Patients With Relapsed or Refractory Lymphomas and Solid Tumors
Where
West Valley City
Age
18 years and over
People
110
Run by
Lantern Pharma Inc.
See details and how to joinNCT06132503
Phase 1/2Taking people
Lu-TARGO (177Lu-TARGeted Osteosarcoma Therapy)
Where
Boston, Los Angeles
Age
12 years and over
People
55
Run by
Lantheus Medical Imaging
See details and how to joinNCT07357519
No phaseTaking people
Comparative Effectiveness Trial of Two Supportive Cancer Care Delivery Models for Adults With Cancer
Where
Birmingham, Duarte, Fresno, Fruitdale, Fullerton, Honolulu, Las Vegas, Los Angeles, Mather, Mobile, Monterey, Palo Alto, Salt Lake City, San Francisco
Age
18 years and over
People
2,996
Run by
Stanford University
See details and how to joinNCT05297734
Phase 2Taking people
A Study of Pembrolizumab Plus Local Chemotherapy Using Isolated Limb Infusion (ILI) for Patients With Sarcoma in the Arm or Leg
Where
Basking Ridge, Commack, Harrison, Middletown, Montvale, New York, Uniondale
Age
12 years and over
People
30
Run by
Memorial Sloan Kettering Cancer Center
See details and how to joinNCT04332874
No phaseTaking people
Assessment of Healing and Function After Reconstruction Surgery for Bone Sarcomas
Where
Basking Ridge, Harrison, Middletown, New York, Uniondale
Age
4 years and over
People
300
Run by
Memorial Sloan Kettering Cancer Center
See details and how to joinNCT03442465
No phaseTaking people
Pre-operative Hypofractionated Proton Therapy
Where
Washington D.C.
Age
18 years and over
People
40
Run by
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
See details and how to joinNCT05917301
Phase 1Taking people
Vorinostat in Combination With Chemotherapy in Relapsed/Refractory Solid Tumors and CNS Malignancies
Where
Valhalla
Age
1 year to 30 years
People
30
Run by
New York Medical College
See details and how to joinNCT04308330