Sarcoma trials in United States

In United States 300 Also abroad 605

300 trials · From ClinicalTrials.gov, checked 11 November 2026. Ask the study team whether a trial fits you.

Early phase 1Not yet taking people in United States
5-AminoLevulinic Acid Aided Resection Margins in Sarcoma
Where
Aurora
Age
18 years and over
People
20
Run by
University of Colorado, Denver
See details and how to joinNCT07038278
Phase 1Taking people
NKG2D.Zeta-NK Cell Conditioning With C7R.GD2.CAR-T Cells for Patients With Relapsed or Refractory Osteosarcoma or Neuroblastoma
Where
Houston
Age
1 year to 24 years
People
27
Run by
Baylor College of Medicine
See details and how to joinNCT07211737
Phase 1/2Taking people
Trial of Single Protein Encapsulated Doxorubicin, SPEDOX-6 in Advanced Malignancies
Where
Orange
Age
18 years and over
People
67
Run by
University of California, Irvine
See details and how to joinNCT07064018
No phaseTaking people
Abductor Reattachment Methods in Proximal Femur Replacements: What is the Best Method?
Where
Durham
Age
16 years to 75 years
People
50
Run by
Duke University
See details and how to joinNCT03261544
No phaseTaking people
Prospective Study Evaluating the Treatment Outcomes for Localised Recurrent, Resectable Retroperitoneal Liposarcoma
Where
Atlanta, Boston, Columbus, Houston
Age
18 years and over
People
100 worldwide
Run by
Australia and New Zealand Sarcoma Association
See details and how to joinNCT07377747
Early phase 1Not yet taking people in United States
Immune Checkpoint Inhibitor (ICI)-Drug-Drug Interaction (DDI) Study
Where
Indianapolis
Age
18 years and over
People
80
Run by
Indiana University
See details and how to joinNCT07389525
Phase 2Taking people
Repurposing Riluzole for Cancer-Related Cognitive Impairment: A Pilot Trial
Where
Orange
Age
18 years and over
People
75
Run by
University of California, Irvine
See details and how to joinNCT06580002
Phase 1/2Taking people
Atezolizumab Plus Tivozanib in Immunologically Cold Tumor Types
Where
Gainesville
Age
18 years to 99 years
People
29
Run by
University of Florida
See details and how to joinNCT05000294
No phaseTaking people
Targeted Oligometastatic Radiation in Pediatric and Young Adult Patients With Soft Tissue and Bone Sarcoma
Where
Baltimore, Minneapolis, Washington D.C.
Age
Up to 39 years
People
70
Run by
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
See details and how to joinNCT06796543
No phaseTaking people
Locally ablatiVe therApy in oLigO-pRogressive sOlid tUmorS (VALOROUS)
Where
Sacramento
Age
18 years and over
People
250
Run by
University of California, Davis
See details and how to joinNCT06103669
Phase 1/2Taking people
Proton-Spatially Fractionated Radiotherapy and Standard Radiation Therapy for the Treatment of Newly Diagnosed Retroperitoneal Soft Tissue Sarcoma
Where
Chicago
Age
18 years and over
People
28
Run by
Northwestern University
See details and how to joinNCT06327477
No phaseTaking people
Navigation Intervention for Adolescent and Young Adult Cancer Survivors
Where
Pasadena
Age
21 years to 45 years
People
25
Run by
Kaiser Permanente
See details and how to joinNCT07406087
No phaseTaking people
Localized Leiomyosarcoma Biomarker Protocol
Where
Ann Arbor, Nashville, Rochester
People
40
Run by
University of Michigan Rogel Cancer Center
See details and how to joinNCT04925089
Phase 1/2Taking people
Alpha/Beta T and B Cell Depletion With Zoledronic Acid for Solid Tumors
Where
Gainesville
Age
6 months to 25 years
People
27
Run by
University of Florida
See details and how to joinNCT06625190
No phaseTaking people
Clonal Hematopoiesis Chemotherapy and Radiation Effects Study
Where
Boston
Age
18 years and over
People
5,000
Run by
Dana-Farber Cancer Institute
See details and how to joinNCT07675967
No phaseTaking people
Integrated Cancer Repository for Cancer Research
Where
Aitkin, Alliance, Aurora, Bozeman, Brainerd, Canton, Council Bluffs, Daytona Beach, DeLand, Duluth, Fargo, Fayetteville, Fergus Falls, Fort Wayne, Glens Falls, Green Bay, Greenwood Village, Hastings, Holyoke, Kansas City, Liberty, Manchester, Minot, Norfolk, North Kansas City, North Platte, Omaha, Orange City, Overland Park, Palm Coast, Randallstown, Saint Joseph, Tallahassee, Utica, Waterloo, Westminster, Yorkville
Age
19 years to 110 years
People
999,999
Run by
University of Nebraska
See details and how to joinNCT02012699
No phaseTaking people
Metastatic Leiomyosarcoma Biomarker Protocol
Where
Ann Arbor, Boston, Columbus, Houston, Miami, Nashville, New York, Rochester, Santa Monica
People
200 worldwide
Run by
University of Michigan Rogel Cancer Center
See details and how to joinNCT05653388
No phaseTaking people
Individualized Prehabilitation for Enhancing Recovery and Surgical Outcomes in Patients Undergoing Radiotherapy and Surgery for Soft Tissue Sarcoma
Where
Scottsdale
Age
18 years and over
People
33
Run by
Mayo Clinic
See details and how to joinNCT05526417
No phaseTaking people
Deep Phenotyping Gait Deficits in Orthopedic Manifestations of Pediatric Cancer Patients
Where
Memphis
Age
5 years to 20 years
People
300
Run by
St. Jude Children's Research Hospital
See details and how to joinNCT07502885
No phaseTaking people
Familial Investigations of Childhood Cancer Predisposition
Where
Memphis
People
1,500
Run by
St. Jude Children's Research Hospital
See details and how to joinNCT03050268
Phase 2Taking people
Treatment of Newly Diagnosed Rhabdomyosarcoma Using Molecular Risk Stratification and Liposomal Irinotecan Based Therapy in Children With Intermediate and High Risk Disease
Where
Fort Worth, Memphis, Palo Alto
Age
Up to 22 years
People
135
Run by
St. Jude Children's Research Hospital
See details and how to joinNCT06023641
Phase 2Taking people
Avapritinib for the Treatment of CKIT or PDGFRA Mutation-Positive Locally Advanced or Metastatic Malignant Solid Tumors
Where
Houston
Age
18 years and over
People
50
Run by
M.D. Anderson Cancer Center
See details and how to joinNCT04771520
Phase 1Taking people
A Phase 1, First-in-human Study of OKN4395 and Pembrolizumab in Patients With Solid Tumors
Where
Beverly Hills, Houston, Santa Monica
Age
18 years and over
People
146 worldwide
Run by
Epkin
See details and how to joinNCT06789172
Phase 2Taking people
5-Day Preoperative Radiation for Soft Tissue Sarcoma
Where
Palo Alto
Age
18 years and over
People
75
Run by
Stanford University
See details and how to joinNCT06087861
No phaseTaking people
Synovial Sarcoma Registry / Biospecimen Repository
Where
Philadelphia
People
1,000
Run by
Children's Hospital of Philadelphia
See details and how to joinNCT05910307