Sickle cell disease trials in Uganda

In Uganda 6 Also abroad 204

6 trials · From ClinicalTrials.gov, checked 12 November 2026. Ask the study team whether a trial fits you.

Phase 3Taking people
A Study to Investigate the Efficacy and Safety of Crizanlizumab (5 mg/kg) Compared With Placebo in Adolescent and Adult Sickle Cell Disease Patients Who Experience Frequent Vaso-Occlusive Crises (SPARKLE)
Where
Kampala, Masaka, Tororo
Age
12 years to 100 years
People
354 worldwide
Run by
Novartis Pharmaceuticals
See details and how to joinNCT06439082
Phase 3Taking people
A Study to Evaluate How Well Etavopivat Works in People With Sickle Cell Disease
Where
Jinja, Kampala
Age
12 years and over
People
510 worldwide
Run by
Novo Nordisk A/S
See details and how to joinNCT06612268 · EU 2023-509175-16-00
Phase 1/2Taking people
Optimizing Hydroxyurea Therapy in Children With Sickle Cell Anemia In Malaria Endemic Areas: The NOHARM Maximum Tolerated Dose (MTD) Study
Where
Kampala
Age
11 years to 18 years
People
250
Run by
Children's Hospital Medical Center, Cincinnati
See details and how to joinNCT07708714
No phaseTaking people
Uganda Sickle Surveillance Study (US-3)
Where
Kampala
Age
Up to 12 months
People
1,000,000
Run by
Children's Hospital Medical Center, Cincinnati
See details and how to joinNCT06301893
No phaseTaking people
Evaluation of an Information Management and Communication System for Population-wide Point-of-Care Infant Sickle Cell Disease Screening
Where
Jinja
Age
18 years and over
People
24,000
Run by
Makerere University
See details and how to joinNCT07610239
No phaseNot yet taking people in Uganda
Development and Evaluation of an Information Management System and Communication System for Population-wide Point-of-care Infant Sickle Cell Disease Screening
Where
Kampala
Age
Up to 5 years
People
24,000 worldwide
Run by
Makerere University
See details and how to joinNCT06563440