Type 2 diabetes trials in Italy

In Italy 53 Also abroad 1247

53 trials · From ClinicalTrials.gov and EU CTIS (euclinicaltrials.eu), checked 15 November 2026. Ask the study team whether a trial fits you.

Phase 3Taking people
EASi-PROTKT™ - A Study to Test Vicadrostat (BI 690517) Taken Together With Empagliflozin in People With Type 2 Diabetes, High Blood Pressure, and Cardiovascular Disease
Where
Acquaviva delle Fonti, Ancona, Bergamo, Brescia, Catania, Catanzaro, Chieti, Cosenza, Ferrara, Florence, L'aquila, Milan, Monza, Naples, Palermo, Pavia, Pisa, Rivoli, Rome, Savona, Trieste, Turin, Varese
Age
18 years and over
People
11,800 worldwide
Run by
Boehringer Ingelheim
See details and how to joinNCT07064473 · EU 2025-521188-11-00
Phase 3Not yet taking people in Italy
AMBITION 3: A Research Study Investigating How Well Zenagamtide at Higher Dose Levels Lowers Blood Sugar and Body Weight Compared to Semaglutide in People With Type 2 Diabetes Treated With Metformin, SGLT2i, or Both
Where
Acquaviva delle Fonti, Bari, Florence, Milan, Parma, Perugia, Ravenna, Rome, Rozzano
Age
18 years and over
People
1,200 worldwide
Run by
Novo Nordisk A/S
See details and how to joinNCT07931573 · EU 2026-525472-26-00
No phaseTaking people
Type 2 Diabetes, Obesity and Cortisol Excess
Where
Milan, Roma, Siena, Udine
Age
18 years to 75 years
People
3,200
Run by
Istituto Auxologico Italiano
See details and how to joinNCT05759637
Phase 3Active, not recruiting
A Clinical Study to Evaluate the Effects of Enicepatide (RO7795068) in Participants With Obesity or Overweight Without Type 2 Diabetes
Where
Bari, Bergamo, Bologna, Catanzaro, Palermo, Perugia, Pisa, Rome, San Donato Milanese
Age
18 years and over
People
2,000 worldwide
Run by
Hoffmann-La Roche
See details and how to joinNCT07351045 · EU 2025-523104-71-00
Phase 3Taking people
A Clinical Study to Evaluate the Effects of Enicepatide (RO7795068) in Participants With Obesity or Overweight and Type 2 Diabetes
Where
Bari, Bergamo, Bologna, Catanzaro, Milan, Palermo, Perugia, Rome
Age
18 years and over
People
1,600 worldwide
Run by
Hoffmann-La Roche
See details and how to joinNCT07351058 · EU 2025-523106-32-00
No phaseCompleted
Real-World Study of Patients With Type 1 Diabetes Treated With Teplizumab as Part of Managed Access Programs (MAPs)
Where
Ancona, Palermo, Verona
People
60 worldwide
Run by
Sanofi
See details and how to joinNCT07457580
Phase 3Taking people
A Study to Learn About the Study Medicine Called Berobenatide (PF-08653944) in People With Overweight or Obesity
Where
Bologna, Chieti Scalo, Palermo, Rome, Sesto San Giovanni
Age
18 years and over
People
954 worldwide
Run by
Pfizer
See details and how to joinNCT07595549 · EU 2026-525318-75-00
Phase 3Taking people
A Study of Orforglipron (LY3502970) Compared With Dulaglutide in Pediatric Participants With Type 2 Diabetes
Where
Ancona, Florence, Genoa, Messina, Milan, Naples, Verona
Age
10 years to 17 years
People
170 worldwide
Run by
Eli Lilly and Company
See details and how to joinNCT07668336 · EU 2025-524811-35-00
Phase 3Not yet taking people in Italy
A Study of Eloralintide (LY3841136) in Participants With Obesity or Overweight, Type 2 Diabetes, and Increased Cardiovascular Risk
Where
Arezzo, Bologna, Chieti Scalo, Florence, Milan, Modena, Naples, Padova, Parma, Pisa, Rome, Rozzano, Siena, A.O.U. Policlinico Paolo Giaccone, Osepdale Civile Fr 5, ASL Città di Torino
Age
45 years to 64 years
People
3,000 worldwide
Run by
Eli Lilly and Company
See details and how to joinNCT07900633 · EU 2026-525919-14-00
No phaseTaking people
Differentiating Heart Disease Between Adult-onset Autoimmune and Type 2 Diabetes
Where
Rome
Age
30 years and over
People
200
Run by
University of Roma La Sapienza
See details and how to joinNCT07911007
Phase 3Not yet taking people in Italy
A Study to Evaluate Effect of AZD6234 in Adult Participants With Obesity or Overweight With Weight-related Comorbidity Without Type 2 Diabetes Mellitus
Where
Bologna, Milan, Palermo, Pisa, Rome, Rozzano, Sesto San Giovanni, Turin
Age
18 years and over
People
2,500 worldwide
Run by
AstraZeneca
See details and how to joinNCT07784725 · EU 2025-523379-41-00
No phaseTaking people
Phenotyping Patients With Type 2 Diabetes Mellitus and Cancer
Where
Novara
Age
18 years and over
People
779
Run by
Azienda Ospedaliero Universitaria Maggiore della Carita
See details and how to joinNCT06299800
No phaseTaking people
Investigating the Link Between Advanced Glycation End Products (AGEs) and Muscle Wasting in Sarcobesity
Where
Novara
Age
18 years and over
People
195
Run by
Azienda Ospedaliero Universitaria Maggiore della Carita
See details and how to joinNCT06438900
Phase 3Taking people
A Study to Find Out if the Study Drug Elecoglipron Helps Adults With Type 2 Diabetes Mellitus by Comparing it With Semaglutide, a Medicine Already Used to Treat Type 2 Diabetes Mellitus
Where
Bari, Bologna, Chieti, Milan, Modena, Naples, Rome
Age
18 years and over
People
1,200 worldwide
Run by
AstraZeneca
See details and how to joinNCT07662213 · EU 2025-523933-24-00
Phase 3Taking people
KHENERFIN Study: A Trial to Evaluate the Efficacy and Safety of Sonlicromanol in Primary Mitochondrial Diseases
Where
Gussago, Messina, Milan, Pisa, Rome
Age
18 years to 64 years
People
220 worldwide
Run by
Khondrion BV
See details and how to joinNCT06451757 · EU 2025-522361-30-00
Phase 3Taking people
A Master Protocol to Investigate Efficacy and Safety of Elecoglipron in Participants With Obesity or Overweight With or Without T2DM
Where
Bologna, Catania, Chieti, Florence, Latina, Milan, Pisa, Ravenna, Roma, San Donato
Age
18 years and over
People
4,500 worldwide
Run by
AstraZeneca
See details and how to joinNCT07667803
Phase 3Taking people
COLchicine and Non-enteric Coated Aspirin in the Cardiovascular Outcomes Trial of Patients With Type 2 Diabetes
Where
Acquaviva delle Fonti, Ancona, Bagno A Ripoli, Campobasso, Chieti Scalo, Ferrara, Florence, Foggia, Genoa, La Spezia, Milan, Pisa, Pistoia, Ravenna, Turin
Age
55 years to 80 years
People
10,000 worldwide
Run by
Montreal Heart Institute
See details and how to joinNCT05633810 · EU 2024-516646-19-00
Phase 3Active, not recruiting
A Research Study to Look at How Two Different Doses of CagriSema and One Dose of Semaglutide Help People Living With Obesity With or Without Type 2 Diabetes Lose Weight
Where
Ancona, Bologna, Brescia, Catanzaro, Genoa, Messina, Milan, Perugia, Pisa
Age
18 years and over
People
2,500 worldwide
Run by
Novo Nordisk A/S
See details and how to joinNCT07564414 · EU 2025-522488-14-00
No phaseEnrolling by invitation
A Research Study to Examine Blood Sugar Control, Treatment Satisfaction and Adherence in People With Type 2 Diabetes After Switching From Daily Basal Insulin to Once-weekly Insulin Icodec
Where
Bolzano, Catania, Città di Castello, Cuneo, Marano Di Napoli (NA), Milan, Montoro, Padova, Pescara, Province of Macerata, Rome, San Giovanni in Fiore (CS)
Age
18 years and over
People
214
Run by
Novo Nordisk A/S
See details and how to joinNCT07632404
No phaseTaking people
Development of Smart Food /Nutraceutical Solutions Dedicated to Cardiometabolic Disorders in Ageing
Where
Novara
Age
65 years and over
People
15
Run by
Azienda Ospedaliero Universitaria Maggiore della Carita
See details and how to joinNCT07817290
No phaseTaking people
Susceptibility to Infectious Diseases in Obesity
Where
Novara
Age
18 years to 65 years
People
80
Run by
Azienda Ospedaliero Universitaria Maggiore della Carita
See details and how to joinNCT05975541
Phase 3Taking people
A trial to learn how safe elecoglipron is and how well it works in adults living with obesity or excess body weight with or without type 2 diabetes
Where
Bologna, Catania, Chieti, Florence, Latina, Milan, Pisa, Ravenna, Rome, San Donato Milanese
Age
18 years and over
People
1,010 worldwide
Run by
AstraZeneca AB
See details and how to join2025-524688-19-00
Phase 3Not yet taking people in Italy
Study of a DPP 4 inhibitor and an SGLT2 inhibitor used together compared with each treatment alone in adults with type 2 diabetes treated with metformin.
Where
Ascoli Piceno, Catanzaro, Milan, Parma, Rome, Verona
Age
18 years and over
People
760 worldwide
Run by
Tecnimede-Sociedade Tecnico-Medicinal S.A.
See details and how to join2025-524606-15-00
No phaseTaking people
EffectiVenEss of a Rehabilitation Treatment With Nordic Walking in obEse or oveRweight Patients
Where
Milan
Age
18 years and over
People
105
Run by
Fondazione Don Carlo Gnocchi ETS
See details and how to joinNCT05987410
No phaseTaking people
Clinical, Oncologic, and Metabolic Effects of Pancreatic Mass Loss After Pancreatectomy in Non-Diabetic Patients
Where
Rome
Age
18 years and over
People
579
Run by
Fondazione Policlinico Universitario Agostino Gemelli IRCCS
See details and how to joinNCT07608055