Type 2 diabetes trials in United States

In United States 389 Also abroad 1200

389 trials · From ClinicalTrials.gov, checked 12 November 2026. Ask the study team whether a trial fits you.

Phase 3Taking people
Extension Trial to Evaluate the Long-term Efficacy, Safety, and Tolerability of Maridebart Cafraglutide (MARITIME-2-EXTENSION)
Where
Annapolis, Austin, Bellaire, Burke, Canoga Park, Cerritos, Cincinnati, Corpus Christi, Denison, East Greenwich, Gilbert, Kansas City, La Mesa, Las Vegas, Lenexa, Miami, Miami Lakes, Modesto, Monroe, Morehead City, Newton, Orlando, Pomona, Skokie, Trenton, West Des Moines, Weston, Wichita, Winter Park
Age
18 years to 99 years
People
950 worldwide
Run by
Amgen
See details and how to joinNCT07684144 · EU 2025-524788-19-00
No phaseTaking people
Efficacy of mHealth Apps for Health in a Low-income, Type II Diabetic, Hispanic Population
Where
San Diego
Age
18 years to 64 years
People
45
Run by
San Diego State University
See details and how to joinNCT05279729
No phaseTaking people
Efficacy of Using Mobile Health Applications for Health
Where
San Diego
Age
18 years to 64 years
People
30
Run by
San Diego State University
See details and how to joinNCT05589155
No phaseTaking people
Hydration Intervention to Decrease Side Effects Associated With GLP - 1 RA Therapy
Where
Buffalo
Age
18 years to 60 years
People
30
Run by
State University of New York at Buffalo
See details and how to joinNCT07641361
No phaseEnrolling by invitation
Scaling Telehealth Models to Improve Co-morbid Diabetes and Hypertension (Phase II)
Where
Atlanta, New York
Age
21 years and over
People
450
Run by
NYU Langone Health
See details and how to joinNCT06542939
No phaseNot yet taking people in United States
Effect Of Percutaneous Electrical Nerve Field Stimulation on Symptom Control/Nervous System Activity in Patients w/Diabetes Types 1/2
Where
Indianapolis
Age
18 years to 60 years
People
60
Run by
Indiana University
See details and how to joinNCT06783504
No phaseTaking people
Implementation pRogram to Improve Screening and Management for CKD in Diabetes (Program 1) (IRIS-CKD)
Where
Ann Arbor, Birmingham, Duluth, Durham, Houston, St. Petersburg, Temple
Age
18 years and over
People
500
Run by
Duke University
See details and how to joinNCT06906627
No phaseTaking people
Implementation pRogram to Improve Screening and Management for CKD in Diabetes (IRIS-CKD) (Program 2)
Where
Ann Arbor, Birmingham, Duluth, Durham, Houston, St. Petersburg, Temple
Age
18 years and over
People
212
Run by
Duke University
See details and how to joinNCT06906640
No phaseNot yet taking people in United States
The RESPLASH Study
Where
New Orleans
Age
18 years to 75 years
People
20
Run by
Tulane University
See details and how to joinNCT06880562
Phase 3Taking people
A Research Study to Look at How Two Different Doses of CagriSema and One Dose of Semaglutide Help People Living With Obesity With or Without Type 2 Diabetes Lose Weight
Where
Amarillo, Aurora, Austin, Beaver, Belzoni, Birmingham, Buckley, Chesterfield, Chicago, Clearwater, Conyers, Cumberland, Dallas, Escondido, Euless, Fargo, Fleming Island, Gaffney, Gainesville, Gilbert, Gillespie, Green Bay, Greensboro, Greenville, Gurnee, Hatboro, Houston, Jackson, Jacksonville, Katy, Kerrville, Kingsport, La Mesa, Lampasas, Laredo, Lexington, Lincoln, Little Rock, Loma Linda, Longview, Los Alamitos, Maumee, McAllen, Memphis, Meridian, Miami, Minneapolis, Miramar, Morehead City, Morristown, Nashville, Newport News, Newton, Norman, Northridge, Ocoee, Oviedo, Palm Springs, Pelham, Pembroke Pines, Philadelphia, Phoenix, Richfield, Richmond, Rockville, Roswell, Salt Lake City, San Antonio, San Diego, Sandy City, Shavano Park, Skokie, South Jordan, Spartanburg, Statesville, St Louis, Sugar Land, Topeka, Van Nuys, Walnut Creek, West Des Moines, West Seneca, Wilmington, Woodstock
Age
18 years and over
People
2,500 worldwide
Run by
Novo Nordisk A/S
See details and how to joinNCT07564414 · EU 2025-522488-14-00
Phase 3Taking people
Research Study on How People With Type 2 Diabetes Tolerate Switching From Semaglutide to Cagrisema
Where
Albuquerque, Amarillo, Austin, Buckley, Dallas, Fleming Island, Fort Worth, Fountain Valley, Gilbert, Glendora, Greensboro, Hialeah, Honolulu, Houston, Kerrville, La Jolla, Las Vegas, Longview, Los Angeles, Maumee, Mt. Dora, Nashville, Newport News, Newton, North Richland Hills, Northridge, Orange City, Pomona, Sacramento, Salt Lake City, San Antonio, San Diego, Sandy City, Skokie, St. George, Topeka, Waterbury, West Des Moines, West Palm Beach, Wilmington
Age
18 years and over
People
210
Run by
Novo Nordisk A/S
See details and how to joinNCT07817251
No phaseTaking people
A Randomized Controlled Trial of Diabetes Screening Immediately Postpartum (DIP) and Follow Up PP CARE
Where
Columbus
Age
18 years and over
People
104
Run by
Ohio State University
See details and how to joinNCT05909046
No phaseTaking people
NT-ProBNP-based Heart Failure Screening and Prevention Trial in Patients With Type 2 Diabetes: STRONG-DM Study
Where
Dallas
People
300
Run by
University of Texas Southwestern Medical Center
See details and how to joinNCT06593327
Phase 1Taking people
A Study of PATAS Using Single Ascending Doses in Healthy Volunteers and Multiple Ascending Doses in Diabetic Subjects
Where
Chandler, Miami, Port Orange
Age
18 years to 65 years
People
56
Run by
AdipoPharma LLC
See details and how to joinNCT07223333
No phaseNot yet taking people in United States
Glucose, Understanding, Integrated Digital Health, and Engagement (GUIDE) Study
Where
New Haven
Age
18 years to 70 years
People
300
Run by
Yale University
See details and how to joinNCT07689877
No phaseTaking people
A Randomized Comparison of Stage-Based Care Versus Risk Factor-Based Care for Prevention of Cardiovascular Events
Where
Abilene, Akron, Augusta, Aurora, Beaumont, Beverly Hills, Boca Raton, Boston, Bowie, Brooklyn, Camp Hill, Canoga Park, Chandler, Chapel Hill, Charleston, Chicago, Chula Vista, Cleveland, Columbia, Cross City, Denver, Detroit, Dunwoody, Durham, Edgewood, Everett, Fargo, Fayetteville, Flemington, Glenview, Granada Hills, Greenville, Hialeah, Houston, Huntington Park, Indianapolis, Indian Wells, Jackson Heights, Jacksonville, Kalispell, Knoxville, La Jolla, Lake Success, Lancaster, Laredo, Las Vegas, Lewisville, Lincoln, Lithia Springs, Loma Linda, Long Beach, Louisville, Macon, Marlton, McKinney, Meridian, Mesquite, Miami, Miami Beach, Minneapolis, Missoula, Monterey Park, Morehead City, Mount Kisco, Nashville, New Brunswick, Newhall, New Orleans, New York, Norcross, Northridge, Oklahoma City, Orange, Palo Alto, Paramus, Pensacola, Pompano Beach, Powder Springs, Richmond, Riverdale, San Fernando, San Marcos, Savannah, Scottsdale, Seattle, Stephenville, St Louis, Sun City, Tampa, Tarzana, Teaneck, Thomasville, Torrance, Tucson, Tulsa, Valencia, Valley Village, West Des Moines, West Valley City, Winston-Salem, Ypsilanti
Age
55 years and over
People
7,500
Run by
Cleerly, Inc.
See details and how to joinNCT06112418
No phaseTaking people
Using Continuous Glucose Monitoring to Quantify the Effects of NOURISH's Culturally Modified Meals on Asian Americans With Type 2 Diabetes
Where
Stanford
Age
18 years and over
People
30
Run by
Stanford University
See details and how to joinNCT06836479
No phaseEnrolling by invitation
STRIDE: Supporting Early Diabetes Self-Management for Parents
Where
Pleasanton
Age
21 years to 44 years
People
150
Run by
Kaiser Permanente
See details and how to joinNCT07544407
No phaseTaking people
ACCESS 2: AI for pediatriC diabetiC Eye examS Study 2
Where
Baltimore
Age
8 years to 21 years
People
500
Run by
Johns Hopkins University
See details and how to joinNCT05463289
No phaseTaking people
Dietary Insights and Nutritional Education in Adults on GLP-1 Therapy
Where
Columbia
Age
18 years to 65 years
People
50
Run by
University of South Carolina
See details and how to joinNCT07518407
No phaseTaking people
Pre-diabetes in Subject With Impaired Fasting Glucose (IFG) and Impaired Glucose Tolerance (IGT)
Where
San Antonio
Age
18 years to 65 years
People
700
Run by
The University of Texas Health Science Center at San Antonio
See details and how to joinNCT02969798
Phase 4Taking people
Pioglitazone on Heart Failure in Type-2 Diabetes Mellitus Participants
Where
San Antonio
Age
30 years to 70 years
People
78
Run by
The University of Texas Health Science Center at San Antonio
See details and how to joinNCT05838287
Phase 3Taking people
A Study of Eloralintide (LY3841136) in Participants With Obesity, or Overweight Without Type 2 Diabetes
Where
Albuquerque, Atlantis, Baltimore, Bellaire, Dallas, Dunwoody, Escondido, Fountain Valley, Greenville, Honolulu, Hyattsville, Lake Charles, Las Vegas, Lawrenceville, Miami, Monroe, Mt. Dora, Mt. Pleasant, Nashville, Norfolk, Palm Springs, Pembroke Pines, Pensacola, Quincy, Rochester, Rolling Hills Estates, Sacramento, San Antonio, Santa Ana, Scottsdale, Stockbridge, St. Petersburg, Topeka, Troy, Tuscaloosa, Tustin, Uniontown, Warren Township, Waterbury, West Des Moines
Age
18 years and over
People
1,980 worldwide
Run by
Eli Lilly and Company
See details and how to joinNCT07321886 · EU 2025-523657-34-00
No phaseTaking people
A U.S. Pilot Human Investigation of RadiofrEquency Vapor Ablation System to Evaluate Safety, TOleRability, and Effectiveness for Proximal Intestinal Mucosal Ablation in Patients With Type 2 Diabetes Mellitus (RESTORE-1 Study)
Where
Chapel Hill, Newport Beach, Scottsdale
Age
22 years to 65 years
People
20
Run by
Aqua Medical, Inc.
See details and how to joinNCT07355270
No phaseTaking people
Phenotyping Genetic Risk for Type 2 Diabetes
Where
Philadelphia
Age
10 years to 70 years
People
100
Run by
University of Pennsylvania
See details and how to joinNCT04024631