Frontotemporális demencia: ki dolgozik rajta

Intézményenként egy kártya. Célpontra vagy országra szűkítheted a listát.

• Minden célpont
• TDP-43 4
• C9orf72 0
• MAPT 2
• TREM2 0
• CSF1R 0
• SOD1 0
• NRF2 0
• AKT 0
• APOE 0
• CDK4/6 0
• GLP-1 0
• HMGB1 0
• LRRK2 0
• MAPK 0
• NLRP3 0
• SIRT1 0
• SNCA 0
• STING 0
• TP53 0

8+ intézményből 8, a friss publikációk és a nyitott vizsgálatok szerint rendezve. Ez nem minőségi rangsor.

Funded research projects that name this disease in their title, terms or summary and have not ended yet: who is funded, where, how much and until when. Organisations only; the funder's page has the details.

• NIH NINDS · F31

  Characterizing the Role of Gasdermin-Eand Downstream Innate Immune Pathways in Frontotemporal Dementia

  Harvard Medical School· Boston, Egyesült Államok· 45 214 USD awarded in fiscal year 2026· until 2029. szept.

• NIH NIA · R01

  Synapse repair in Alzheimer's disease and related dementias

  Buck Institute for Research on Aging· Novato, Egyesült Államok· 785 081 USD awarded in fiscal year 2026· until 2031. júl.

• NIH NINDS · R56

  Unraveling Mechanisms Governing Cell Clearance Deficits in C9ORF72-ALS/FTD

  University of Missouri-Columbia· Columbia, Egyesült Államok· 539 427 USD awarded in fiscal year 2026· until 2027. aug.

• NIH NIA · R44

  Clinical Evaluation of a Novel [18F] Positron Emission Tomography (PET) Tracer for Differential Diagnosis and Staging of 4R Tauopathies

  Enigma Biomedical Usa, Inc· Knoxville, Egyesült Államok· 896 719 USD awarded in fiscal year 2026· until 2029. máj.

• NIH NINDS · R44

  The Therapeutic Development of a Clinical NR1H3 Antisense Oligonucleotide to Reprogram Microglia into a Neuroprotective State in ALS and FTD

  Modulo Bio, Inc.· San Diego, Egyesült Államok· 847 695 USD awarded in fiscal year 2026· until 2028. aug.

• European Commission (Horizon Europe) · HORIZON-TMA-MSCA-SE

  From Stool to Solutions: Diagnose, Decode, Disruptors, and Deliver Interventions for the Human Gut Microbiota in Neurodegenerative Diseases. (GUT-4D)

  Universita Degli Studi del Piemonte Orientale Amedeo Avogadro· Vercelli, Olaszország· EU contribution 1 568 130 EUR· until 2030. szept.· 8 countries

  The disease is named only in the funder's project summary, not in the title.

• European Commission (Horizon Europe) · HORIZON-TMA-MSCA-PF-EF

  Unraveling the impact of RNA-editing in neurodegeneration: a focus on TDP-43 related frontotemporal dementia. (NeuroEDIT)

  Asociacion Instituto de Investigacion Sanitaria Biogipuzkoa· Donostia-San Sebastian, Spanyolország· EU contribution 194 075 EUR· until 2028. aug.· 2 countries

• European Commission (Horizon Europe) · HORIZON-TMA-MSCA-DN

  The role of cellular mechanical stress in the pathogenesis of neurodegenerative disorders (NEUROMECH)

  Universita Degli Studi Dell'aquila· L Aquila, Olaszország· EU contribution 2 647 675 EUR· until 2029. dec.· 8 countries

  The disease is named only in the funder's project summary, not in the title.

• European Commission (Horizon Europe) · HORIZON-ERC

  Targeting rogue DNA repair and genomic instability as novel toxicity mechanisms in C9orf72 ALS/FTD (epiC9repair)

  Deutsches Zentrum fur Neurodegenerative Erkrankungen Ev· Bonn, Németország· EU contribution 2 498 905 EUR· until 2030. okt.

• European Commission (Horizon Europe) · HORIZON-TMA-MSCA-SE

  Translational METabolomics for NEurodegenerative Diseases dIAgnosis and prognosis (METNEDIA)

  Universita Degli Studi del Piemonte Orientale Amedeo Avogadro· Vercelli, Olaszország· EU contribution 1 107 210 EUR· until 2029. okt.· 5 countries

  The disease is named only in the funder's project summary, not in the title.

10 of 492 running projects, newest first. Listed amounts together: 391,9 M USD + 17,7 M EUR.

Sources: NIH RePORTER (U.S. National Institutes of Health, public domain) and CORDIS (European Commission, CC BY 4.0). Changes: filtered by disease, organisations matched to ROR.

Vizsgálatok, amelyek regiszteradata szerint az egyéni résztvevői adatokat (IPD) megosztják.

• A Study to Evaluate the Safety, Tolerability and Pharmacodynamics of NIO752 in Primary Tauopathies

  NCT07868328· Novartis Pharmaceuticals· Forrás

Publikációk erről a betegségről egy MeSH-módszerkifejezés szerint, például szekvenálási vagy képalkotó módszerre.

• Single-Cell Analysis 1
• Organoids 4
• Mendelian Randomization Analysis 10
• CRISPR-Cas Systems 1
• Gene Expression Profiling 4
• Whole Genome Sequencing 3
• Exome Sequencing 1
• Proteomics 17
• Metabolomics 1
• Mass Spectrometry 1
• Flow Cytometry 2
• Immunohistochemistry 1
• Positron-Emission Tomography 28
• Magnetic Resonance Imaging 74
• Machine Learning 18
• Deep Learning 9
• Cohort Studies 34
• Genome-Wide Association Study 13

• Multidomain Electroencephalography Biomarker Fusion for Machine Learning-Based Dementia Classification.

  J Vis Exp, 2026. szept.

• Machine learning for predicting full-count FDG PET brain images from low-count acquisitions in suspected dementia: a clinical and quantitative evaluation.

  Phys Med Biol, 2026. aug.

• Comparative Screening of Alzheimer's Disease, Lewy Body Dementia, and Frontotemporal Dementia Using miRNA and Machine Learning.

  Int J Neural Syst, 2026. júl.

• Explainable EEG-based machine learning for early diagnosis of Alzheimer's disease and frontotemporal dementia.

  Sci Rep, 2026. jún.

• Dementia etiology classification using NULISA plasma biomarkers and machine learning.

  Alzheimers Dement, 2026. jún.

• Speech-based digital biomarkers for early etiological stratification of Alzheimer's disease and frontotemporal degeneration: a biomarker-confirmed prospective study.

  J Prev Alzheimers Dis, 2026. ápr.

• Chronological Diagnostic Algorithm Predicting Neuropathology in Parkinsonism.

  Ann Neurol, 2026. márc.

  Dennis W Dickson

• Identifying neuropathologic disease in primary progressive aphasia using narrative speech.

  Alzheimers Dement, 2026. márc.

• Graph empirical mode decomposition and multiscale feature extraction for EEG-based classification of Alzheimer's disease and frontotemporal dementia.

  Comput Methods Programs Biomed, 2026. febr.

• A Unique EEG-Hyfusion Fully Automated Stacked Model for Classification of Alzheimer's Disease and Fronto-Temporal Dementia.

  J Vis Exp, 2026. febr.

Megmutatjuk, a betegség mely célpontjait említi az absztrakt, és onnan a rajtuk dolgozókhoz jutsz.