Időskori makuladegeneráció: ki dolgozik rajta

Intézményenként egy kártya. Célpontra vagy országra szűkítheted a listát.

• Minden célpont
• VEGF 19
• NRF2 0
• GLP-1 0
• PPAR 0
• AKT 0
• JNK 0
• APOE 0
• PI3K 0
• SIRT1 0
• ALK 1
• AMPK 0
• MAPK 0
• mTOR 0
• GPX4 0
• JAK 0
• NLRP3 0
• TP53 0
• ERK 0
• PCSK9 0
• STAT3 0
• STING 0
• YAP 0
• BCL-2 0
• CTNNB1 0
• CXCR4 0
• HIF-1 0
• IL-6 0
• MMP-9 1
• PDGFR 0
• SGLT2 1
• TNF 0
• IL-17 0
• MDM2 0
• MYC 0
• NOTCH3 0
• PKM2 0
• RPGR 0
• SOD1 0
• TERT 0
• TFEB 0
• TREM2 0

38+ intézményből 24, a friss publikációk és a nyitott vizsgálatok szerint rendezve. Ez nem minőségi rangsor.

Funded research projects that name this disease in their title, terms or summary and have not ended yet: who is funded, where, how much and until when. Organisations only; the funder's page has the details.

• European Commission (Horizon Europe) · HORIZON-TMA-MSCA-PF-EF

  Decoding retinal cell communication to counteract vision loss in aging (VisionGuard)

  Aarhus Universitet· Aarhus C, Dánia· EU contribution 263 393 EUR· until 2029. ápr.

• European Commission (Horizon Europe) · HORIZON-TMA-MSCA-PF-EF

  Drusen Reconstitution in an Engineered AMD Model using Retinal Pigment Epithelium (DREAM_RPE)

  Universidade Nova de Lisboa· Lisboa, Portugália· EU contribution 207 183 EUR· until 2028. dec.

• European Commission (Horizon Europe) · HORIZON-TMA-MSCA-DN

  Doctoral network on discovering pathomechanisms and novel drug optimization for AMD (PANDORA)

  Eberhard Karls Universitaet Tuebingen· Tuebingen, Németország· EU contribution 4 020 973 EUR· until 2030. szept.· 8 countries

• European Commission (Horizon Europe) · HORIZON-ERC-POC

  Full field optoretinography for elderly eye health (FFORGE)

  Institut National de la Sante Et de la Recherche Medicale· Paris, Franciaország· EU contribution 150 000 EUR· until 2028. febr.

  The disease is named only in the funder's project summary, not in the title.

• European Commission (Horizon Europe) · HORIZON-TMA-MSCA-PF-EF

  Lysophagy as a new strategy for neuroprotection in dry AMD (AMD_Prog)

  Universite de Fribourg· Fribourg, Svájc· EU contribution 307 959 EUR· until 2028. aug.

5 of 12 running projects, newest first. Listed amounts together: 21,9 M EUR.

Sources: NIH RePORTER (U.S. National Institutes of Health, public domain) and CORDIS (European Commission, CC BY 4.0). Changes: filtered by disease, organisations matched to ROR.

Leállított, visszavont és felfüggesztett vizsgálatok, a szponzor által a regiszterben megadott okkal, szó szerint idézve.

• Visszavonták

  An Observational Study to Investigate the Use of Aflibercept 8 mg to Treat Adult Patients With Neovascular Age-Related Macular Degeneration (nAMD) and Diabetic Macular Edema (DME) in a Real-World Setting

  NCT06398080· Regeneron Pharmaceuticals· Frissítve: 2024. nov. 25.

  “Sponsor Decision”A regiszter szövege, változtatás nélkül. Forrás

• Visszavonták

  Optical Coherence Tomography Angiography (OCTA) - Directed PDT Triple Therapy

  NCT04075136· Wake Forest University Health Sciences· Frissítve: 2024. márc. 22.

  “IRB stopped study due to safety concerns before any participants were enrolled.”A regiszter szövege, változtatás nélkül. Forrás

Vizsgálatok, amelyek regiszteradata szerint az egyéni résztvevői adatokat (IPD) megosztják.

• Phase 1b/2a Study of EYC-0305 in Patients With Neovascular Age-related Macular Degeneration

  NCT07587515· Eyconis INC.· Forrás

• Speculum-Free Intravitreal Injection Using Cotton-Tipped Applicator Retraction: Pain, Procedure Time, Patient Satisfaction, and Safety

  NCT07481500· Jakkrit Juhong· Forrás

• A Study to Evaluate the Long-Term Safety and Tolerability of Faricimab in Participants With Neovascular Age-Related Macular Degeneration

  NCT04777201· Hoffmann-La Roche· Forrás

• Efficacy and Safety of Two Different Brolucizumab 6 mg Dosing Regimens in Neovascular Age-related Macular Degeneration

  NCT04679935· Novartis Pharmaceuticals· Forrás

• Effect of Video Viewing on Intravitreal Injection Experience

  NCT07002372· Second Affiliated Hospital, Zhejiang University, School of Medicine· Forrás

Publikációk erről a betegségről egy MeSH-módszerkifejezés szerint, például szekvenálási vagy képalkotó módszerre.

• Single-Cell Analysis 5
• Organoids 11
• Mendelian Randomization Analysis 26
• CRISPR-Cas Systems 7
• Gene Expression Profiling 16
• Sequence Analysis, RNA 3
• Whole Genome Sequencing 1
• Exome Sequencing 2
• Proteomics 21
• Metabolomics 16
• Mass Spectrometry 11
• Flow Cytometry 8
• Immunohistochemistry 15
• Liquid Biopsy 1
• Magnetic Resonance Imaging 6
• Machine Learning 14
• Deep Learning 31
• Cohort Studies 26
• Genome-Wide Association Study 24

• Metabolic mediators linking gut microbiota to age-related macular degeneration: A Mendelian randomization study.

  Medicine (Baltimore), 2026. okt.

• Integrative Genomic Analyses Prioritize CETP-Related Lipid Traits in Age-Related Macular Degeneration.

  Invest Ophthalmol Vis Sci, 2026. okt.

• Integrative Proteogenomics and Single-Cell Transcriptomics Prioritize Candidate Causal Proteins and Therapeutic Targets in Age-Related Macular Degeneration.

  Int J Mol Sci, 2026. szept.

• Genetic evidence and cross-species functional characterization implicate CNN2 in age-related macular degeneration susceptibility.

  Proc Natl Acad Sci U S A, 2026. szept.

• Standard tea intake is causally associated with a reduced risk of wet age-related macular degeneration: a Mendelian randomization study.

  Physiol Genomics, 2026. aug.

• Blood DNA methylation at AMD candidate loci in discordant monozygotic twins.

  Sci Rep, 2026. júl.

• Causal Effects of Dietary Macronutrients and Micronutrients on Myopia and Other Major Ocular Disorders: A Mendelian Randomization Study.

  J Vis Exp, 2026. máj.

• Bidirectional causal associations between immune cell phenotypes and age-related macular degeneration subtypes: A mendelian randomization study.

  Exp Gerontol, 2026. febr.

• Opportunities and challenges in leveraging multiomics and biobanks for vision science.

  Curr Opin Ophthalmol, 2026. febr.

• A 2-step, 2-sample Mendelian randomization study of gut microbiota, blood metabolites and dry age-related macular degeneration.

  Medicine (Baltimore), 2026. febr.

Megmutatjuk, a betegség mely célpontjait említi az absztrakt, és onnan a rajtuk dolgozókhoz jutsz.