Osteoarthritis: ki dolgozik rajta

Intézményenként egy kártya. Célpontra vagy országra szűkítheted a listát.

• Minden célpont
• PI3K 0
• NRF2 0
• NLRP3 0
• MAPK 0
• AMPK 1
• GLP-1 3
• IL-1 1
• AKT 0
• mTOR 0
• STAT3 0
• SIRT1 0
• TLR4 0
• JAK 0
• COX-2 0
• ERK 0
• CTNNB1 0
• IL-6 0
• PPAR 0
• STING 0
• TP53 0
• GPX4 0
• HIF-1 0
• JNK 0
• TNF 0
• YAP 0
• PINK1 0
• PTEN 0
• VEGF 0
• IL-17 0
• METTL3 0
• RANKL 0
• EGFR 0
• BCL-2 0
• CXCR4 0
• FTO 0
• HMGB1 0
• MMP-9 0
• SGLT2 1
• CGRP 0
• FGFR 0
• HDAC 0
• KEAP1 0
• MDM2 0
• PARP 0
• APOE 0
• BRD4 0
• CDK4/6 0
• ESR1 0
• FAK 0
• GIP 0
• HER2 0
• HSP90 0
• MEK 0
• NMDA 0
• TREM2 0
• APP 0
• AR 0
• ARID1A 0
• CD47 0
• CFTR 0

3100 intézményből 24, a friss publikációk és a nyitott vizsgálatok szerint rendezve. Ez nem minőségi rangsor.

Funded research projects that name this disease in their title, terms or summary and have not ended yet: who is funded, where, how much and until when. Organisations only; the funder's page has the details.

• NIH NIA · F30

  Dissecting Age-related Changes in Stem Cell-based Bone-Gut Crosstalk

  University of California at Davis· Davis, Egyesült Államok· 43 752 USD awarded in fiscal year 2026· until 2029. szept.

• NIH NINDS · R43

  Development of an Anti-Nerve Growth Factor Active Immunotherapy for Difficult-to-Manage Pain

  Twilight Bioscience, Inc.· Topsfield, Egyesült Államok· 350 188 USD awarded in fiscal year 2026· until 2028. aug.

• NIH NIAMS · R56

  Understanding the Roles of Synovitis, Knee-Adjacent Obesity and Sarcopenia in Pain Phenotypes and Structural Progression of Knee Osteoarthritis - An Analysis of the Entire Osteoarthritis Initiative

  University of California, San Francisco· San Francisco, Egyesült Államok· 620 656 USD awarded in fiscal year 2026· until 2027. aug.

• NIH NIAMS · R01

  Fe Metabolism Compromises Articular Chondrocytes during Joint Degeneration

  University of Iowa· Iowa City, Egyesült Államok· 660 873 USD awarded in fiscal year 2026· until 2031. aug.

• NIH NIDCR · R43

  SN102: a Novel Gene Therapy for Trigeminal Neuralgia Pain

  Sereneuro Therapeutics, Inc.· Baltimore, Egyesült Államok· 338 115 USD awarded in fiscal year 2026· until 2027. szept.

• European Commission (Horizon Europe) · HORIZON-ERC

  Biofabrication of gene activated grafts targeting synovial joint inflammation and meniscus repair (SMART-MENISCUS)

  The Provost, Fellows, Foundation Scholars & the Other Members of Board, of the College of the Holy & Undivided Trinity of Queen Elizabeth Near Dublin· Dublin, Írország· EU contribution 1 500 000 EUR· until 2032. jan.

  The disease is named only in the funder's project summary, not in the title.

• European Commission (Horizon Europe) · HORIZON-RIA

  EV-enriched secretome from cord blood as a new disease modifying treatment for osteoarthritis (ExoCordOA)

  Exogenus Therapeutics Sa· Cantanhede, Portugália· EU contribution 13 000 000 EUR· until 2031. aug.· 3 countries

• European Commission (Horizon Europe) · HORIZON-TMA-MSCA-PF-EF

  Smart Platforms for Osteochondral Regeneration through on-demand Activation (SPORA)

  Instituto Superior Tecnico· Lisboa, Portugália· EU contribution 191 343 EUR· until 2028. aug.

• European Commission (Horizon Europe) · HORIZON-TMA-MSCA-PF-EF

  Newly engineered lignin nanocarrier for curcumin delivery to tackle inflammation and limited synovial drug residence in osteoarthritis (LigNPsCURCDeLIV)

  University of Leeds· Leeds, Egyesült Királyság· EU contribution 276 188 EUR· until 2028. szept.

• European Commission (Horizon Europe) · HORIZON-TMA-MSCA-PF-EF

  Gene-activated tri-layer 3D-bioprinted scaffold for enhanced osteochondral defect repair (GATSO-3D)

  Royal College of Surgeons in Ireland· Dublin 2, Írország· EU contribution 252 729 EUR· until 2028. júl.

  The disease is named only in the funder's project summary, not in the title.

10 of 421 running projects, newest first. Listed amounts together: 229,9 M USD + 106,0 M EUR.

Sources: NIH RePORTER (U.S. National Institutes of Health, public domain) and CORDIS (European Commission, CC BY 4.0). Changes: filtered by disease, organisations matched to ROR.

Leállított, visszavont és felfüggesztett vizsgálatok, a szponzor által a regiszterben megadott okkal, szó szerint idézve.

• Leállították

  Rotator Cuff Sparing Total Arthroplasty

  NCT01961986· NYU Langone Health· Frissítve: 2026. nov. 13.

  “Terminated because sufficient data has been collected to do analysis and a manuscript has been published.”A regiszter szövege, változtatás nélkül. Forrás

• Visszavonták

  Measurement of Osteoarthritic Patient Pain Through Electrodermal Activity Signals

  NCT06701461· Dartmouth-Hitchcock Medical Center· Frissítve: 2026. nov. 13.

  “The study was not pursued”A regiszter szövege, változtatás nélkül. Forrás

• Leállították

  Preoperative Immunonutrition in Patients Undergoing Spine Surgery

  NCT05372289· I.R.C.C.S Ospedale Galeazzi-Sant'Ambrogio· Frissítve: 2026. nov. 13.

  “Poor accrual”A regiszter szövege, változtatás nélkül. Forrás

• Felfüggesztve

  Effects of Home Base Whole-body Vibration in Osteoarthritis. (VIBE-Rx2)

  NCT06058169· Augusta University· Frissítve: 2026. nov. 2.

  “funding issues”A regiszter szövege, változtatás nélkül. Forrás

• Visszavonták

  Efficacy & Safety of Fluoroquinolone-Based Brucellosis Regimens (BRUCE)

  NCT07779629· The First Affiliated Hospital of Shihezi University· Frissítve: 2026. okt. 27.

  “This original trial NCT07779629 was withdrawn before any participant enrollment. The protocol was split into two independent new trials: NCT07887126 and NCT07887152. These two new trials have separate IRB approvals and will be conducted and analyzed”A regiszter szövege, változtatás nélkül. Forrás

• Leállították

  Pain Relief After Trapeziectomy: Ibuprofen & Acetaminophen Versus Oxycodone

  NCT04676802· Stanford University· Frissítve: 2026. okt. 27.

  “Study drug supply unavailable”A regiszter szövege, változtatás nélkül. Forrás

• Leállították

  Evaluation of Structural and Functional Integrity of the Rotator Cuff After Total Shoulder Arthroplasty

  NCT03921944· Milton S. Hershey Medical Center· Frissítve: 2026. okt. 20.

  “low enrollment”A regiszter szövege, változtatás nélkül. Forrás

• Felfüggesztve

  TKR Rehabilitation Through the Immersive Virtual Reality in Aquatic Scenarios

  NCT04241172· IRCCS San Raffaele Roma· Frissítve: 2026. okt. 19.

  “Due to technical issues with the necessary facilities at the participating centers, the PIs have decided to suspend the study until the devices and hydrotherapy pool are fully operational.”A regiszter szövege, változtatás nélkül. Forrás

• Leállították

  Generate and Test the Reliability of a PD Model of OXT on Pupillary Hippus as a Measure of CNS Activity

  NCT04427709· Wake Forest University Health Sciences· Frissítve: 2026. okt. 13.

  “This study was initiated for preliminary data to support NIH grant submission. The study was maintained active in anticipation of returning to the protocol. Due to funding and current NIH grant work this study could not be completed.”A regiszter szövege, változtatás nélkül. Forrás

• Leállították

  ROSA® Hip System THA PMCF

  NCT05497206· Zimmer Biomet· Frissítve: 2026. okt. 13.

  “The data needed for regulatory submissions based on the current pace of the study, will not be available in the foreseeable future.”A regiszter szövege, változtatás nélkül. Forrás

Vizsgálatok, amelyek regiszteradata szerint az egyéni résztvevői adatokat (IPD) megosztják.

• Intracapsular Injection of Human Umbilical Cord Mesenchymal Stem Cells for the Treatment of Knee Osteoarthritis

  NCT07935083· Beijing Hospital· Forrás

• Three Variants of the PENG Block With and Without Perineural Adjuvants in Older Adults

  NCT07330999· Poznan University of Medical Sciences· Forrás

• Osteoarthritis Care Tools for Primary Care Providers in Family Medicine and Geriatrics Clinics

  NCT07925710· University of North Carolina, Chapel Hill· Forrás

• Comparison of Platelet-rich Plasma and Activated Cytokine-rich Serum Injection Treatments in Patients With Knee Osteoarthritis. (KOA PRP ACS)

  NCT07473232· Pamukkale University· Forrás

• The Feasibility of a Virtual/Home-based OA Treatment Program in Older Adults With OA and Multimorbidity

  NCT07921563· Dartmouth-Hitchcock Medical Center· Forrás

• ESPB vs iPACK+ACB in Total Knee Arthroplasty

  NCT06302218· Poznan University of Medical Sciences· Forrás

• SIRI Levels Following PENG Block in Hip Arthroplasty

  NCT07449403· Poznan University of Medical Sciences· Forrás

• Effects of Virtual Reality Environments on Walking in Adults With and Without Knee Osteoarthritis

  NCT07920120· University of Primorska· Forrás

• ACB and iPACK Blocks With Intravenous Dexamethasone and Perineural Dexmedetomidine in Total Knee Arthroplasty

  NCT07677215· Poznan University of Medical Sciences· Forrás

• A Study to Learn About Study Medicine Called Berobenatide in Adults With Knee Pain and Overweight or Obesity (VESPER-OA 1)

  NCT07919678· Pfizer· Forrás

Publikációk erről a betegségről egy MeSH-módszerkifejezés szerint, például szekvenálási vagy képalkotó módszerre.

• Single-Cell Analysis 43
• Organoids 4
• Mendelian Randomization Analysis 56
• CRISPR-Cas Systems 1
• Gene Expression Profiling 106
• Sequence Analysis, RNA 11
• Whole Genome Sequencing 3
• Exome Sequencing 1
• Proteomics 43
• Metabolomics 26
• Mass Spectrometry 5
• Flow Cytometry 7
• Immunohistochemistry 19
• Positron-Emission Tomography 6
• Magnetic Resonance Imaging 276
• Machine Learning 78
• Deep Learning 45
• Cohort Studies 148
• Genome-Wide Association Study 48

• Proteomic landscape of IGF-I gene transfer in osteoarthritis-derived human bone marrow stromal cells undergoing chondrogenesis.

  Arthritis Res Ther, 2026. okt.

• Mapping articular cartilage maturation across postnatal development by proteomics.

  Osteoarthritis Cartilage, 2026. jún.

• Revisiting osteoarthritis as an inflammatory disease: characterization of synovitis grading and synovial pathotypes in surgical specimens.

  Arthritis Res Ther, 2026. ápr.

• Recombinant IL-38 Alleviates Temporomandibular Joint Synovial Inflammation via IL-1R1-NF-κB-IL1β Pathway.

  Int Dent J, 2026. ápr.

• Proprioceptive role of the abductor pollicis longus in thumb carpometacarpal osteoarthritis: An anatomical and immunohistochemical study.

  Osteoarthritis Cartilage, 2026. ápr.

• Relationship between asporin expression and the pathological progression of murine temporomandibular joint osteoarthritis after partial discectomy.

  J Oral Biosci, 2026. ápr.

• HSPA4 and SYVN1 positivity in osteoarthritis synovium as indicators of proteostasis dysfunction.

  Clin Exp Rheumatol, 2026. febr.

• Complementary roles of HMGB1 and PRDX4 in the pathophysiology of steroid-associated osteonecrosis of the femoral head: a histopathological and immunohistochemistry study.

  Virchows Arch, 2026. febr.

• Inflammatory gradients in the infrapatellar fat pad of knee osteoarthritis: implications for joint damage.

  Arthritis Res Ther, 2025. dec.

• Histological and Immunohistochemical Methods in Normal and Osteoarthritic Knee Cartilage of Rat and Rabbit Models: A Literature Review.

  Int J Mol Sci, 2025. okt.

Megmutatjuk, a betegség mely célpontjait említi az absztrakt, és onnan a rajtuk dolgozókhoz jutsz.