Singapore General Hospital

Researchers

• LWLiang En Wee

Running trials

• Not yet recruiting

  A Study to Learn How Well People With Bronchiectasis Tolerate Continued Treatment With Verducatib After Earlier Studies (AIRTIVITY®-ON)

  NCT07915219· Phase 3· Boehringer Ingelheim· Source

• Not yet recruiting

  Mailed FIT-Based Outreach Interventions

  NCT07852793· National Cancer Centre, Singapore· Source

• Recruiting

  A Phase 3 Study of INCA033989 Versus Best Available Therapy in Participants With Essential Thrombocythemia

  NCT07623200· Phase 3· Incyte Corporation· Source

• Recruiting

  Asia Myelodysplastic Syndrome (MDS) Registry

  NCT07355478· Bristol-Myers Squibb· Source

• Not yet recruiting

  Formative Evaluation of a Mobile Application Facilitated Self-directed Rehabilitation Programme for Knee Osteoarthritis

  NCT07773480· Singapore General Hospital· Source

• Not yet recruiting

  Durian Consumption in Adults With Type 2 Diabetes Mellitus

  NCT07697612· Singapore General Hospital· Source

• Recruiting

  A Study to Test Whether Nerandomilast Helps People With Systemic Sclerosis

  NCT07497087· Phase 3· Boehringer Ingelheim· Source

• Not yet recruiting

  Restoring Bile Acid Homeostasis Via Lifestyle Adjustments to Prevent the Development of Liver Cancer

  NCT07111130· National Cancer Centre, Singapore· Source

• Recruiting

  Outpatient Physiotherapy vs. mHealth Exercise and Self-Management for Knee Osteoarthritis (MOKneeTOR)

  NCT07767409· Singapore General Hospital· Source

• Recruiting

  Complementary Herbal Approach to Rheumatoid Management Study (CHARMS)

  NCT07627893· Phase 2/3· Singapore General Hospital· Source

• Recruiting

  AP-NOSES: A Prospective Multicentre Registry of Natural Orifice Specimen Extraction in Minimally Invasive Colorectal Surgery

  NCT07615036· Singapore General Hospital· Source

• Not yet recruiting

  AI-Powered Closed-Loop Multielectrode Transcutaneous Spinal Cord Stimulation: Real-Time Adjustments for Enhanced Motor Recovery in Spinal Cord Injury (AIM RECOVER)

  NCT07452133· Singapore General Hospital· Source

• Not yet recruiting

  Home-Based Digital Rehabilitation Program Optimized With Transcutaneous Spinal Cord Stimulation for Upper Limb Functional Enhancement in Tetraplegia (HOPE): A Safety, Efficacy, and Feasibility Study

  NCT07438353· Singapore General Hospital· Source

• Recruiting

  Scalp Hair Metabolomics in Severe Obesity

  NCT07368842· Singapore General Hospital· Source

• Recruiting

  Focal or Radical Therapy: a Lesion-based Molecular Evaluation in Prostate Cancer

  NCT07282808· Singapore General Hospital· Source

• Recruiting

  Histotripsy for Ablation of Liver Tumours in Asia

  NCT07428356· National Cancer Centre, Singapore· Source

• Recruiting

  Dietary Glycine Supplementation in Metabolic Dysfunction-associated Steatotic Liver Disease

  NCT07285135· Singapore General Hospital· Source

• Recruiting

  Patient Outcomes Following Kinematic and Functional Alignment in Robotic-Assisted Total Knee Arthroplasty With Randomized Insert Types

  NCT07533188· Singapore General Hospital· Source

• Recruiting

  A Study to Evaluate the Safety and Efficacy of Tacabrutideg (BGB-16673) Compared to Pirtobrutinib in Adults With Relapsed/Refractory Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma

  NCT06973187· Phase 3· BeOne Medicines· Source

• Recruiting

  EASi-PROTKT™ - A Study to Test Vicadrostat (BI 690517) Taken Together With Empagliflozin in People With Type 2 Diabetes, High Blood Pressure, and Cardiovascular Disease

  NCT07064473· Phase 3· Boehringer Ingelheim· Source

• Active, not recruiting

  P1101 in Treating Patients With Early PMF or Overt PMF at Low or Intermediate-1 Risk

  NCT06468033· Phase 3· PharmaEssentia· Source

• Recruiting

  A Study of Mezagitamab in Adults With Kidney Condition Called IgA Nephropathy

  NCT06963827· Phase 3· Takeda· Source

• Recruiting

  An Artificial Intelligence-powered Approach to Precision Immunotherapy of Human Arthritis

  NCT07013110· Phase 2· Prof Salvatore Albani· Source

• Recruiting

  The AIRTIVITY™ Study: A Study to Find Out Whether BI 1291583 Helps People With Bronchiectasis

  NCT06872892· Phase 3· Boehringer Ingelheim· Source

• Not yet recruiting

  Assessing the Feasibility of the Patient-Reported Outcomes Based Model for Community Care of Patients With Axial Spondyloarthritis Via a Type 1 Pilot Hybrid Effectiveness-Implementation Trial Using the RE-AIM Framework

  NCT06968247· Singapore General Hospital· Source

• Active, not recruiting

  VITUS Post-Market Registry

  NCT06832631· OrbusNeich· Source

• Recruiting

  Acoramidis Transthyretin Amyloidosis Prevention Trial in the Young (ACT-EARLY) Study in Asymptomatic Carriers of a Pathogenic TTR Variant

  NCT06563895· Phase 3· Eidos Therapeutics, a BridgeBio company· Source

• Recruiting

  Endoscopic Conversion of Sleeve Gastrectomy to Single Anastomosis Sleeve-ileal Bypass (SASI) for Gastroesophageal Reflux (GERD), Primary and Secondary Non-responder.

  NCT06757296· Singapore Health Services· Source

• Recruiting

  Treatment Response in Immune-mediated Myositis Associated Rapidly-progressing Interstitial Lung Disease

  NCT07775235· Singapore General Hospital· Source

• Active, not recruiting

  A Phase 3 Study of NTLA-2001 in ATTRv-PN

  NCT06672237· Phase 3· Intellia Therapeutics· Source

• Recruiting

  LIVERAGE™ - Cirrhosis: A Study to Test Whether Survodutide Helps People With a Liver Disease Called NASH/MASH Who Have Cirrhosis

  NCT06632457· Phase 3· Boehringer Ingelheim· Source

• Recruiting

  LIVERAGE™: A Study to Test Whether Survodutide Helps People With a Liver Disease Called NASH/MASH Who Have Moderate or Advanced Liver Fibrosis

  NCT06632444· Phase 3· Boehringer Ingelheim· Source

• Active, not recruiting

  A Follow-up Study to Test Long-term Treatment With Nerandomilast in People With Pulmonary Fibrosis Who Took Part in a Previous Study With Nerandomilast

  NCT06238622· Phase 3· Boehringer Ingelheim· Source

• Recruiting

  Multi-modal Training Program to Promote Physical Activity After Stroke

  NCT06409351· Singapore General Hospital· Source

• Recruiting

  A Study to Evaluate the Efficacy and Safety of Tulisokibart (MK-7240) in Participants With Moderate to Severe Crohn's Disease (MK-7240-008)

  NCT06430801· Phase 3· Merck Sharp & Dohme LLC· Source

• Recruiting

  Efficacy and Safety of CSL222 (Etranacogene Dezaparvovec) Gene Therapy in Adults With Hemophilia B With Pretreatment Adeno-associated Virus Serotype 5 (AAV5) Neutralizing Antibodies (Nabs)

  NCT06003387· Phase 3· CSL Behring· Source

• Recruiting

  App-based Diabetes Management and Community-based Interventions

  NCT06688903· Singapore General Hospital· Source

• Not yet recruiting

  Outcomes With Treatment and Withdraw of Secukinumab in Patients With Plaque Psoriasis

  NCT04239859· Phase 4· Singapore General Hospital· Source

• Recruiting

  Tissue Sodium Quantification in Patients With Primary Aldosteronism: See Sodium to Treat

  NCT06569589· Jens Titze· Source

• Recruiting

  A Study of Opevesostat (MK-5684) Versus Alternative Next-generation Hormonal Agent (NHA) in Metastatic Castration-resistant Prostate Cancer (mCRPC) Post One NHA (MK-5684-004)

  NCT06136650· Phase 3· Merck Sharp & Dohme LLC· Source

• Active, not recruiting

  A Study to Evaluate Efficacy and Safety of Tulisokibart (MK-7240) in Participants With Moderately to Severely Active Ulcerative Colitis (MK-7240-001)

  NCT06052059· Phase 3· Merck Sharp & Dohme LLC· Source

• Recruiting

  A Trial to Learn How Well Linvoseltamab Works Compared to the Combination of Elotuzumab, Pomalidomide and Dexamethasone for Adult Participants With Relapsed/Refractory Multiple Myeloma

  NCT05730036· Phase 3· Regeneron Pharmaceuticals· Source

• Recruiting

  Seladelpar in Subjects With Primary Biliary Cholangitis (PBC) and Compensated Cirrhosis

  NCT06051617· Phase 3· Gilead Sciences· Source

• Active, not recruiting

  A Study to Evaluate the Efficacy and Safety of Sefaxersen (RO7434656) in Participants With Primary Immunoglobulin A (IgA) Nephropathy at High Risk of Progression

  NCT05797610· Phase 3· Hoffmann-La Roche· Source

• Recruiting

  Breast Cancer Exercise Intervention Study

  NCT05957068· National Cancer Centre, Singapore· Source

• Recruiting

  Prospective Asian Multicenter Prostate Cancer Focal Therapy Study (ProAMFocal)

  NCT06491056· Singapore General Hospital· Source

• Active, not recruiting

  Genotype Guided Antiplatelet Therapy In Ischemic Stroke

  NCT05763862· National Neuroscience Institute· Source

• Active, not recruiting

  A Study of Milvexian Versus Apixaban in Participants With Atrial Fibrillation

  NCT05757869· Phase 3· Janssen Research & Development, LLC· Source

• Recruiting

  Deep, Multi-omics Phenotyping to Predict Response, Resistance and Recurrence to Adjuvant Atezolizumab Plus Bevacizumab in Resected Hepatocellular Carcinoma

  NCT05516628· Phase 2· National Cancer Centre, Singapore· Source

• Active, not recruiting

  A Study of Milvexian in Participants After an Acute Ischemic Stroke or High-Risk Transient Ischemic Attack- LIBREXIA-STROKE

  NCT05702034· Phase 3· Janssen Research & Development, LLC· Source

Showing 50 of 83.

Recruiting at the same time

How many trials recruit for the same indication here at once. A count, not a rating.

• Liver and biliary tract cancer4 recruiting
• Fatty liver disease (MASLD/MASH)3 recruiting
• Obesity3 recruiting
• Osteoarthritis3 recruiting
• Peripheral artery disease3 recruiting
• Prostate cancer3 recruiting
• Type 2 diabetes3 recruiting
• Colorectal cancer2 recruiting
• High blood pressure2 recruiting
• Liver cirrhosis2 recruiting
• Psoriasis2 recruiting
• Rheumatoid arthritis2 recruiting
• Spinal cord injury2 recruiting
• Acute lymphoblastic leukaemia1 recruiting
• Amyloidosis1 recruiting
• Ankylosing spondylitis1 recruiting
• Bronchiectasis1 recruiting
• Childhood cancers1 recruiting
• Chronic lymphocytic leukaemia1 recruiting
• Crohn's disease1 recruiting
• Dermatomyositis and polymyositis (myositis)1 recruiting
• Haemophilia1 recruiting
• Hepatitis B1 recruiting
• Idiopathic pulmonary fibrosis1 recruiting
• IgA nephropathy1 recruiting
• Lung cancer1 recruiting
• Metastatic breast cancer1 recruiting
• Myelodysplastic syndromes1 recruiting
• Myeloproliferative neoplasms1 recruiting
• Primary biliary cholangitis1 recruiting
• Stroke1 recruiting
• Systemic sclerosis (scleroderma)1 recruiting

Closed trials

• Completed

  Investigating the Prevalence and Risk Factors for Sarcopenia Amongst Adults Seeking Treatment for Obesity

  NCT07541677· Singapore General Hospital· Source

• Completed

  Assessment of Revascularization in Plantar Foot of Diabetic Patients Pre and Post Angioplasty Using Spatial Frequency Domain Imaging

  NCT07097857· Singapore General Hospital· Source

• Completed

  A Study to Test Whether BI 1819479 Improves Lung Function in People With Idiopathic Pulmonary Fibrosis (IPF)

  NCT06335303· Phase 2· Boehringer Ingelheim· Source

• Completed

  A Study to Learn About How Well BAY3283142 Works and Its Safety in Participants With Chronic Kidney Disease

  NCT06522997· Phase 2· Bayer· Source

• Completed

  Inspire Singapore Study

  NCT06540716· Inspire Medical Systems, Inc.· Source

• Completed

  Safety, Tolerability, PK & PD of AB-101 Following Oral Administration in Healthy and CHB Subjects.

  NCT05960240· Phase 1· Arbutus Biopharma Corporation· Source

• Completed

  MLC1501 Study Assessing Efficacy in Post STrOke Subjects With mOtor Deficits

  NCT05289947· Phase 2· Moleac Pte Ltd.· Source

• Completed

  A Phase 2b, Randomized, Double-blind Study of Redasemtide (S-005151) in Adult Participants With Acute Ischemic Stroke

  NCT05953480· Phase 2· Shionogi· Source

• Completed

  A Clinical Study of Efinopegdutide in Participants With Precirrhotic Nonalcoholic Steatohepatitis (NASH) (MK-6024-013)

  NCT05877547· Phase 2· Merck Sharp & Dohme LLC· Source

• Completed

  Late Feasibility Study to Evaluate Safety and Efficacy of AWAK PD Device in Subjects With ESKD.

  NCT05827588· AWAK Technologies Pte Ltd· Source

• Completed

  A Study Assessing Rocatinlimab in Combination With Topical Corticosteroid and/or Topical Calcineurin Inhibitors in Adult Participants With Moderate-to-severe Atopic Dermatitis (AD)

  NCT05724199· Phase 3· Amgen· Source

• Completed

  A Study in People With Systemic Sclerosis to Test Whether Avenciguat (BI 685509) Has an Effect on Lung Function and Other Systemic Sclerosis Symptoms

  NCT05559580· Phase 2· Boehringer Ingelheim· Source

• Completed

  A Study to Find Out Whether BI 1015550 Improves Lung Function in People With Idiopathic Pulmonary Fibrosis (IPF)

  NCT05321069· Phase 3· Boehringer Ingelheim· Source

• Withdrawn

  Evaluate the Performance of JOURNEY II CR and JOURNEY II BCS in TKA Populations

  NCT04822259· Smith & Nephew, Inc.· Source

• Terminated

  A Study to Test Whether BI 685509 Alone or in Combination With Empagliflozin Helps People With Liver Cirrhosis Caused by Viral Hepatitis or Non-alcoholic Steatohepatitis (NASH) Who Have High Blood Pressure in the Portal Vein (Main Vessel Going to the Liver)

  NCT05282121· Phase 2· Boehringer Ingelheim· Source

• Completed

  Using the Blood Eosinophil Count to Guide Systemic Corticosteroid Treatment in Asthma Exacerbations

  NCT05417906· Phase 2· Changi General Hospital· Source

• Terminated

  A Study to Test Whether Two Different Doses of Avenciguat Help People With Liver Cirrhosis and High Blood Pressure in the Portal Vein (Main Vessel Going to the Liver)

  NCT05161481· Phase 2· Boehringer Ingelheim· Source

• Terminated

  Evaluate the Performance of JOURNEY II CR in TKA Populations

  NCT04818840· Smith & Nephew, Inc.· Source

• Completed

  A Trial to Learn How Well Finerenone Works and How Safe it is in Adult Participants With Non-diabetic Chronic Kidney Disease

  NCT05047263· Phase 3· Bayer· Source

• Completed

  Research Study on Whether a Combination of 2 Medicines (NNC0194 0499 and Semaglutide) Works in People With Non-alcoholic Steatohepatitis (NASH)

  NCT05016882· Phase 2· Novo Nordisk A/S· Source

• Completed

  Study to Evaluate the Safety and Efficacy of Selgantolimod (SLGN)-Containing Combination Therapies for the Treatment of Chronic Hepatitis B (CHB)

  NCT04891770· Phase 2· Gilead Sciences· Source

• Terminated

  An Open-Label Phase 2 Trial of Nanatinostat Plus Valganciclovir in Patients With EBV+ Relapsed/Refractory Lymphomas

  NCT05011058· Phase 2· Viracta Therapeutics, Inc.· Source

• Completed

  A Study to Test Safety and Efficacy of Survodutide (BI456906) in Adults With Non-alcoholic Steatohepatitis (NASH) and Fibrosis (F1-F3)

  NCT04771273· Phase 2· Boehringer Ingelheim· Source

• Recruiting

  A Study of Axatilimab at 3 Different Doses in Participants With Chronic Graft Versus Host Disease (cGVHD)

  NCT04710576· Phase 2· Syndax Pharmaceuticals· Source

• Completed

  Assessing the Utility of Peak Inspiratory Flow as a Predictor for COPD Exacerbations

  NCT04360226· Respiratory Effectiveness Group· Source

• Completed

  Long-term Safety and Efficacy Study of Lebrikizumab (LY3650150) in Participants With Moderate-to-Severe Atopic Dermatitis (ADjoin)

  NCT04392154· Phase 3· Eli Lilly and Company· Source

• Terminated

  NOLA (NeuWave Observational Liver Ablation) Registry

  NCT04107766· Ethicon, Inc.· Source

• Completed

  11C-Metomidate PET/CT for Endocrine Hypertension and Characterisation of Adrenal Tumours

  NCT06100367· Phase 2/3· Changi General Hospital· Source

• Completed

  Nasal High Flow Therapy in Surgical Patients with Unrecognized Obstructive Sleep Apnea

  NCT03964376· University Health Network, Toronto· Source

• Completed

  Window of Opportunity Study in Colorectal Cancer

  NCT03984578· Phase 2· National Cancer Centre, Singapore· Source

• Completed

  A Study to Evaluate Upadacitinib in Adolescents and Adults With Moderate to Severe Atopic Dermatitis (Measure Up 2)

  NCT03607422· Phase 3· AbbVie· Source

• Completed

  A Study Comparing Upadacitinib (ABT-494) to Placebo and to Adalimumab in Participants With Psoriatic Arthritis Who Have an Inadequate Response to at Least One Non-Biologic Disease Modifying Anti-Rheumatic Drug (DMARD)

  NCT03104400· Phase 3· AbbVie· Source

• Completed

  Filgotinib in Long-Term Extension Study of Adults With Ulcerative Colitis

  NCT02914535· Phase 3· Alfasigma S.p.A.· Source

• Completed

  Stem Cell Transplantation With NiCord® (Omidubicel) vs Standard UCB in Patients With Leukemia, Lymphoma, and MDS

  NCT02730299· Phase 3· Gamida Cell ltd· Source

• Completed

  Ponatinib in Participants With Resistant Chronic Phase Chronic Myeloid Leukemia (CP-CML) to Characterize the Efficacy and Safety of a Range of Doses

  NCT02467270· Phase 2· Takeda· Source

• Completed

  A Randomized Controlled Trial of TNK-tPA Versus Standard of Care for Minor Ischemic Stroke With Proven Occlusion

  NCT02398656· Phase 3· University of Calgary· Source

• Completed

  Prospective Multi-centre Outcomes Study of Persona Knee System in Total Knee Arthroplasty

  NCT04461626· Zimmer Biomet· Source

• Completed

  Study Comparing Combination of LGX818 Plus MEK162 Versus Vemurafenib and LGX818 Monotherapy in BRAF Mutant Melanoma

  NCT01909453· Phase 3· Pfizer· Source

Conditions

Diseases this institution publishes on or runs trials for.

• Fatty liver disease (MASLD/MASH)33 works · 5 trials
• Osteoporosis23 works · 0 trials
• Obstructive sleep apnoea16 works · 2 trials
• Chronic myeloid leukaemia13 works · 3 trials
• Psoriatic arthritis12 works · 2 trials
• Ankylosing spondylitis8 works · 2 trials
• Liver cirrhosis6 works · 4 trials
• Familial hypercholesterolaemia4 works · 0 trials