Epilepsy: who works on it

One card per institution. Pick a target or a country to narrow the list.

• All targets
• NMDA 0
• mTOR 3
• SCN1A 6
• SCN2A 2
• HMGB1 0
• PPAR 0
• BDNF 1
• NLRP3 0
• TLR4 0
• NRF2 0
• PTEN 0
• AKT 0
• PI3K 0
• IDH 0
• GLP-1 0
• IL-1 1
• JAK 0
• GPX4 0
• AMPK 0
• CTNNB1 1
• MAPK 0
• APOE 0
• COX-2 0
• SGLT2 0
• SIRT1 0
• STING 0
• TNF 0
• ERK 1
• HIF-1 0
• STAT3 0
• TP53 0
• TREM2 0
• CGRP 0
• HDAC 0
• MAPT 0
• YAP 0
• APP 0
• CXCR4 0
• HSP90 0
• IL-6 0
• JNK 0
• MDM2 0
• NOTCH1 0
• NOTCH3 0
• PD-1 0
• PINK1 0
• AQP4 0
• AR 0
• B7-H3 0
• BACE1 0
• BCL-2 0
• BRAF 0
• BRD4 0
• CD47 0
• DMD 0
• DPP-4 0
• FGFR 0
• FTO 0
• G6PD 0
• GBA1 0

1 of 1+ institutions, ordered by recent publications and open trials. This is not a ranking of quality.

Funded research projects that name this disease in their title, terms or summary and have not ended yet: who is funded, where, how much and until when. Organisations only; the funder's page has the details.

• NIH NIMH · F30

  Neural Correlates of Memory-Based Generalization in Humans

  University of California at Davis· Davis, United States· US$43,749 awarded in fiscal year 2026· until Sept 2030

• ALLCDC NCCDPHP · U01

  Epilepsy Incidence Among Children in the United States

  National Opinion Research Center· Chicago, United States· US$443,851 awarded in fiscal year 2025· until Sept 2030

• ALLCDC NCCDPHP · U01

  Advancing Understanding of Pediatric Epilepsy Incidence and Risk Factors: A Multilevel Population Health Approach

  Massachusetts General Hospital· Boston, United States· US$418,550 awarded in fiscal year 2025· until Sept 2030

• NIH NINDS · F31

  Slow-Wave Sleep Enhancement to Treat Epilepsy

  University of California at Davis· Davis, United States· US$43,749 awarded in fiscal year 2026· until Sept 2029

• ALLCDC NCCDPHP · U01

  Incidence and Risk Factors of Childhood Epilepsy in the United States

  Case Western Reserve University· Cleveland, United States· US$499,995 awarded in fiscal year 2025· until Sept 2030

• European Commission (Horizon Europe) · HORIZON-ERC

  From single neuron to brain: multi-level strategy and digital twins for personalized prediction of treatment (Neuron2Brain)

  Universita Degli Studi di Genova· Genova, Italy· EU contribution €1,500,000· until Feb 2032

• European Commission (Horizon Europe) · HORIZON-TMA-MSCA-PF-EF

  Unravelling the Role of Cerebral Amyloid-beta Angiopathy in Epilepsy: Inflammatory Pathways and Interneuron Dysfunction (EPICAA)

  Ludwig-Maximilians-Universitaet Muenchen· Planegg, Germany· EU contribution €217,965· until Feb 2029

• European Commission (Horizon Europe) · HORIZON-TMA-MSCA-PF-GF

  The role of subcortical structures in perceptual consciousness: a causal investigation (StimConscious)

  Katholieke Universiteit Leuven· Leuven, Belgium· EU contribution €424,129· until Jan 2030· 3 countries

  The disease is named only in the funder's project summary, not in the title.

• European Commission (Horizon Europe) · HORIZON-ERC-POC

  Standardized patient‑friendly computational language mapping to guide epilepsy surgery (SPEEDY-Clinic)

  Institut National de la Sante Et de la Recherche Medicale· Paris, France· EU contribution €150,000· until Jun 2028

• European Commission (Horizon Europe) · HORIZON-TMA-MSCA-PF-EF

  High-throughput screen for disfunctions in GABA-switch in human neuronal models of SNAREopathies

  Kobenhavns Universitet· Kobenhavn, Denmark· EU contribution €247,553· until Oct 2028

  The disease is named only in the funder's project summary, not in the title.

10 of 1,267 running projects, newest first. Listed amounts together: US$616.7m + €184.0m.

Sources: NIH RePORTER (U.S. National Institutes of Health, public domain) and CORDIS (European Commission, CC BY 4.0). Changes: filtered by disease, organisations matched to ROR.

Trials whose registry record says individual participant data (IPD) will be shared.

• Online Study of People Who Have Genetic Changes and Features of Autism: Simons Searchlight

  NCT01238250· Simons Searchlight· Source

Find publications on this disease by a MeSH method term, for example a sequencing or imaging method.

• Single-Cell Analysis 8
• Organoids 13
• Mendelian Randomization Analysis 36
• CRISPR-Cas Systems 9
• Gene Expression Profiling 28
• Sequence Analysis, RNA 4
• Whole Genome Sequencing 14
• Exome Sequencing 114
• Proteomics 23
• Metabolomics 23
• Mass Spectrometry 7
• Flow Cytometry 3
• Immunohistochemistry 21
• Liquid Biopsy 1
• Xenograft Model Antitumor Assays 2
• Positron-Emission Tomography 70
• Magnetic Resonance Imaging 572
• Machine Learning 112
• Deep Learning 78
• Cohort Studies 313
• Genome-Wide Association Study 37

• Development of a human iPSC and patient phenotyping resource for preclinical investigations of neurodevelopmental disorders.

  Stem Cell Res, Aug 2026

• Generation of a FRMD5 knockout human embryonic stem cell line by CRISPR/Cas9 editing.

  Stem Cell Res, Jun 2026

• CRISPR-Based Gene Therapy for Brain Disease.

  Mol Neurobiol, Jun 2026

• Gene Editing Strategies for Neurological and Mental Disorders: Advances in Delivery, Methodology, and Clinical Translation.

  Cells, Apr 2026

• Targeted Gene and Genome-Editing Strategies for Epilepsy: Experimental Advances and Translational Challenges.

  Int J Mol Sci, Mar 2026

• Isogenic modeling of 1q21.1 reciprocal CNVs in human ES cells reveals divergent neurodevelopmental trajectories.

  Hum Mol Genet, Feb 2026

• Generation of a SV2A knockout human embryonic stem cell line by CRISPR/Cas9 system.

  Stem Cell Res, Feb 2026

• Engineering a human-based translational activator for targeted protein expression restoration.

  Nucleic Acids Res, Feb 2026

• A hit for base editing: treatment of developmental epilepsy in a mouse model.

  J Clin Invest, Feb 2026

See which targets of this disease your abstract mentions, and go to the people working on them.